SG11201903443QA - Composite particles including anionic polymer and cationic polymer or peptide, and method for producing composite particles - Google Patents

Composite particles including anionic polymer and cationic polymer or peptide, and method for producing composite particles

Info

Publication number
SG11201903443QA
SG11201903443QA SG11201903443QA SG11201903443QA SG11201903443QA SG 11201903443Q A SG11201903443Q A SG 11201903443QA SG 11201903443Q A SG11201903443Q A SG 11201903443QA SG 11201903443Q A SG11201903443Q A SG 11201903443QA SG 11201903443Q A SG11201903443Q A SG 11201903443QA
Authority
SG
Singapore
Prior art keywords
composite particles
peptide
polymer
anionic polymer
cationic polymer
Prior art date
Application number
SG11201903443QA
Other languages
English (en)
Inventor
Ryota Hayashi
Original Assignee
Pola Chem Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2016203809A external-priority patent/JP6901841B2/ja
Priority claimed from JP2016204693A external-priority patent/JP6956478B2/ja
Application filed by Pola Chem Ind Inc filed Critical Pola Chem Ind Inc
Publication of SG11201903443QA publication Critical patent/SG11201903443QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • A61K8/0283Matrix particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11Encapsulated compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88Polyamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5161Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00Manufacture or treatment of nanostructures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10General cosmetic use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mathematical Physics (AREA)
  • Medical Informatics (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cosmetics (AREA)
SG11201903443QA 2016-10-17 2017-10-04 Composite particles including anionic polymer and cationic polymer or peptide, and method for producing composite particles SG11201903443QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2016203809A JP6901841B2 (ja) 2016-10-17 2016-10-17 アニオン性ポリマー及びペプチドを含む複合粒子及びその製造方法
JP2016204693A JP6956478B2 (ja) 2016-10-18 2016-10-18 アニオン性ポリマー及びカチオン性ポリマーを含む複合粒子
PCT/JP2017/036146 WO2018074237A1 (ja) 2016-10-17 2017-10-04 アニオン性ポリマー及びカチオン性ポリマー若しくはペプチドを含む複合粒子並びにその製造方法

Publications (1)

Publication Number Publication Date
SG11201903443QA true SG11201903443QA (en) 2019-05-30

Family

ID=62019641

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201903443QA SG11201903443QA (en) 2016-10-17 2017-10-04 Composite particles including anionic polymer and cationic polymer or peptide, and method for producing composite particles

Country Status (9)

Country Link
US (2) US11707419B2 (de)
EP (2) EP3799858A1 (de)
KR (3) KR102215375B1 (de)
CN (3) CN113995731A (de)
ES (1) ES2971884T3 (de)
MY (1) MY192816A (de)
SG (1) SG11201903443QA (de)
TW (1) TWI784978B (de)
WO (1) WO2018074237A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3799858A1 (de) * 2016-10-17 2021-04-07 Pola Chemical Industries Inc. Verfahren zur herstellung von verbundteilchen
KR102099842B1 (ko) * 2019-09-26 2020-04-10 (주)리젠바이오참 조직재생용 하이드로겔 조성물 및 이를 이용하여 제조된 지지체
JP2021095361A (ja) * 2019-12-17 2021-06-24 ロレアル ヒアルロン酸系ポリイオンコンプレックス粒子を含む組成物
US20230149683A1 (en) * 2020-02-24 2023-05-18 B. G. Negev Technologies and Applications Itd., at Ben-Gurion university Methods for Enhancing Transdermal and Intradermal Delivery of Glycosaminoglycans (GAGs)
CN112063221B (zh) * 2020-09-18 2022-11-15 山东华熙海御生物医药有限公司 含透明质酸的着色助剂、制法及其应用
US20240033201A1 (en) * 2020-12-14 2024-02-01 L'oreal Composition comprising polyion complex particle and filler
FR3118700A1 (fr) * 2021-01-13 2022-07-15 L'oreal Composition comprenant une particule de complexe polyionique et une charge
CN114699335B (zh) * 2022-04-25 2023-11-03 广州创尔生物技术股份有限公司 一种稳定的胶原蛋白-透明质酸互溶体系及其制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7056338B2 (en) * 2003-03-28 2006-06-06 Conor Medsystems, Inc. Therapeutic agent delivery device with controlled therapeutic agent release rates
ES2226567B1 (es) * 2003-06-20 2006-07-01 Universidad De Santiago De Compostela Nanoparticulas de acido hialuronico.
JP4461727B2 (ja) * 2003-07-18 2010-05-12 チッソ株式会社 外用剤組成物
WO2005089106A2 (en) * 2004-02-27 2005-09-29 Molecular Therapeutics, Inc. Degradable nanoparticles
ES2259914B1 (es) 2005-03-14 2007-06-16 Advanced In Vitro Cell Technologies, S.L. Nanoparticulas de quitosano y polietilenglicol como sistema de administracion de moleculas biologicamente activas.
US20070110813A1 (en) * 2005-11-02 2007-05-17 Aeris Therapeutics, Inc. Polycation-polyanion complexes, compositions and methods of use thereof
CN101448939B (zh) 2006-05-17 2011-12-14 小山义之 用于导入核酸、寡核酸或其衍生物的冷冻干燥体
KR20090031861A (ko) 2006-05-24 2009-03-30 어드밴스드 인 비트로 셀 테크놀로지스, 에스.에이 활성분자의 투여를 위한 키토산 및 하이알루로난 나노입자
EP2166022B1 (de) * 2007-04-24 2016-09-21 Q.P. Corporation Kationisierte hyaluronsäure und/oder salz davon, herstellungsverfahren dafür und haarmodfizierungsmittel, mittel zur reparatur der kutikulaschicht, hautmodifizierungsmittel und kosmetische zubereitung mit diesen
JP5085976B2 (ja) * 2007-05-09 2012-11-28 株式会社 資生堂 球状複合ゲル粒子の製造方法
EP2152293B1 (de) 2007-05-11 2016-10-19 The Board of Regents of the University of Nebraska Zusammensetzungen zur proteinabgabe und verfahren zu deren verwendung
WO2009079066A2 (en) * 2007-09-26 2009-06-25 Aparna Biosciences Therapeutic and vaccine polyelectrolyte nanoparticle compositions
US8093365B2 (en) * 2008-03-03 2012-01-10 New York University Biocompatible materials containing stable complexes method of TSG-6 and hyaluronan and method of using same
EP2172193A1 (de) 2008-10-02 2010-04-07 Capsulution Nanoscience AG Verbesserte Nanopartikel-Zusammensetzungen schlecht löslicher Verbindungen
US20110256059A1 (en) * 2008-10-28 2011-10-20 Universidade De Santiago De Compostela Nanoparticulate systems prepared from anionic polymers
US9028797B2 (en) * 2010-02-26 2015-05-12 Nagasaki University Composite body for antigen or drug delivery
CN102210871A (zh) * 2010-07-16 2011-10-12 钟术光 缓释释药的药物载体
JP6292655B2 (ja) 2012-10-11 2018-03-14 ポーラ化成工業株式会社 キトサン及びヒアルロナンを含むナノ粒子
JP6162943B2 (ja) * 2012-11-02 2017-07-12 ポーラ化成工業株式会社 ヒアルロナンを含むナノ粒子
EP3024887B1 (de) * 2013-07-26 2023-11-22 The Penn State Research Foundation Verfahren zur herstellung von polymerzusammensetzungen und beschichtungen damit
EP3064213A4 (de) * 2013-10-28 2017-04-26 Terumo Kabushiki Kaisha Wässrige proteinsuspension
WO2015189387A1 (en) 2014-06-13 2015-12-17 Sanofi Nanocapsular formulation of active pharmaceutical ingredients
JP6602626B2 (ja) 2015-09-28 2019-11-06 嘉寛 徳留 ヒアルロナンを含む複合粒子を含有する乳化組成物
CN105726511A (zh) * 2016-03-10 2016-07-06 温州医科大学 一种自发组装的多聚赖氨酸接枝物纳米粒及其制备与应用
EP3799858A1 (de) * 2016-10-17 2021-04-07 Pola Chemical Industries Inc. Verfahren zur herstellung von verbundteilchen

Also Published As

Publication number Publication date
KR20190059303A (ko) 2019-05-30
KR102301456B1 (ko) 2021-09-10
ES2971884T3 (es) 2024-06-10
KR102301452B1 (ko) 2021-09-10
TWI784978B (zh) 2022-12-01
EP3527194A1 (de) 2019-08-21
US20190231655A1 (en) 2019-08-01
CN109862876A (zh) 2019-06-07
EP3799858A1 (de) 2021-04-07
EP3527194A4 (de) 2020-08-19
KR20200123274A (ko) 2020-10-28
CN115192468A (zh) 2022-10-18
EP3527194B1 (de) 2024-02-14
WO2018074237A1 (ja) 2018-04-26
US20200289380A1 (en) 2020-09-17
EP3527194C0 (de) 2024-02-14
MY192816A (en) 2022-09-09
CN115192468B (zh) 2024-02-13
TW201828916A (zh) 2018-08-16
US11707419B2 (en) 2023-07-25
US12029800B2 (en) 2024-07-09
KR102215375B1 (ko) 2021-02-15
CN109862876B (zh) 2022-07-22
CN113995731A (zh) 2022-02-01
KR20200122431A (ko) 2020-10-27

Similar Documents

Publication Publication Date Title
SG11201903443QA (en) Composite particles including anionic polymer and cationic polymer or peptide, and method for producing composite particles
WO2016196315A3 (en) Cell culture methods and systems
MX2016003740A (es) Particulas de dioxido de titanio y un proceso para su produccion.
MX2015017526A (es) Método para la fabricación de un producto perfilado de ácido hialurónico.
SA516380356B1 (ar) مشتتات مطلية من ثاني أكسيد التيتانيوم
PH12018502469A1 (en) Molecular modification of polyethylene resin
MX2017010882A (es) Un producto de concreto fotocatalitico y un metodo para generar un producto de concreto fotocatalitico.
WO2016193351A3 (en) Recombinant microorganism for improved production of fine chemicals
EP3590970A4 (de) Fasercellulose, fasercellulosehaltige zusammensetzung, flüssige dispersion von fasercellulose und verfahren zur herstellung von fasercellulose
WO2019023057A3 (en) TREATMENT OF MINERAL OR STERILE RESIDUES OF PHOSPHATES
MX2011007731A (es) Pigmentos formadores de pelicula y sistema de recubrimiento que incluye los mismos.
MY191789A (en) Production of glycolaldehyde by thermolytic fragmentation
EP3680290A4 (de) Cellulosenanofaserflüssigdispersion, cellulosenanofaserverbundharz und verfahren zur herstellung von dispersion und harz
MX2019008977A (es) Tratamiento de composiciones acuosas que incluyen finos.
BR112018076542A2 (pt) método para preparar partículas contendo celulose
EP3238548A4 (de) Verfahren zur herstellung von rohpillen aus fermentierten mineralien mit funktion zur verbesserung von darmverstopfung und erholung von erschöpfungszuständen sowie damit hergestellte rohpillen aus fermentierten mineralien
EP3275919A4 (de) Wässrige dispersion aus gelpartikeln, verfahren zur herstellung davon und bilderzeugungsverfahren
WO2009041275A1 (ja) 樹脂微粒子水分散体の製造方法及びこの製造方法にて得られた樹脂微粒子水分散体、樹脂微粒子
MX2015003203A (es) Proceso para mejorar las propiedades reologicas de una dispersion acuosa.
WO2019095024A3 (en) Method for production of microcrystalline cellulose
WO2019018370A3 (en) TREATMENT OF BITUMINOUS SAND RESIDUES
SE1751603A1 (en) Improved process for manufacturing composite product
EP3222667A4 (de) Sphärische monodispersible wässrige polyesterharzdispersion, verfahren zur herstellung davon, sphärischer monodispersibler polyesterharzpartikel und kosmetikprodukt
WO2018110846A3 (ko) 기능화된 그래핀의 제조 방법
MX2015011383A (es) Particulas opacificantes con hueco interno y metodos para la fabricacion de las mismas.