SG11201903254PA - Undifferentiated stem cell-removing agent, and method for removing undifferentiated stem cells - Google Patents

Undifferentiated stem cell-removing agent, and method for removing undifferentiated stem cells

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Publication number
SG11201903254PA
SG11201903254PA SG11201903254PA SG11201903254PA SG11201903254PA SG 11201903254P A SG11201903254P A SG 11201903254PA SG 11201903254P A SG11201903254P A SG 11201903254PA SG 11201903254P A SG11201903254P A SG 11201903254PA SG 11201903254P A SG11201903254P A SG 11201903254PA
Authority
SG
Singapore
Prior art keywords
undifferentiated stem
cell
undifferentiated
removing agent
stem cell
Prior art date
Application number
SG11201903254PA
Other languages
English (en)
Inventor
Shugo Tohyama
Keiichi Fukuda
Jun Fujita
Sho Tanosaki
Original Assignee
Univ Keio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Keio filed Critical Univ Keio
Publication of SG11201903254PA publication Critical patent/SG11201903254PA/en

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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  • Molecular Biology (AREA)
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  • Virology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Heart & Thoracic Surgery (AREA)
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SG11201903254PA 2016-10-17 2017-10-17 Undifferentiated stem cell-removing agent, and method for removing undifferentiated stem cells SG11201903254PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016203839 2016-10-17
PCT/JP2017/037495 WO2018074457A1 (ja) 2016-10-17 2017-10-17 未分化幹細胞除去剤、及び未分化幹細胞除去方法

Publications (1)

Publication Number Publication Date
SG11201903254PA true SG11201903254PA (en) 2019-05-30

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SG11201903254PA SG11201903254PA (en) 2016-10-17 2017-10-17 Undifferentiated stem cell-removing agent, and method for removing undifferentiated stem cells

Country Status (11)

Country Link
US (1) US20190300857A1 (zh)
EP (1) EP3527657A4 (zh)
JP (1) JP6811489B2 (zh)
KR (1) KR102218042B1 (zh)
CN (1) CN110050060A (zh)
AU (1) AU2017346898B2 (zh)
CA (1) CA3040637C (zh)
IL (1) IL265980A (zh)
RU (1) RU2735247C1 (zh)
SG (1) SG11201903254PA (zh)
WO (1) WO2018074457A1 (zh)

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US20190300857A1 (en) * 2016-10-17 2019-10-03 Keio University Undifferentiated stem cell-removing agent, and method for removing undifferentiated stem cells
CN111117951A (zh) * 2018-10-30 2020-05-08 澳门大学 通过IGF/胰岛素通路调节hPSC分化方向的方法及应用
WO2020139914A1 (en) * 2018-12-26 2020-07-02 Academia Sinica Methods for regulating potency of pluripotent stem cells and applications thereof
KR102262557B1 (ko) * 2020-01-10 2021-06-09 주식회사 히에라바이오 심장 줄기세포의 기능성을 강화하는 방법
CN111979175A (zh) * 2020-08-28 2020-11-24 安徽惠恩生物科技股份有限公司 一种清除干细胞分化体系中残留的多能干细胞的方法

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JP6744084B2 (ja) * 2014-11-11 2020-08-19 キリンホールディングス株式会社 幹細胞由来の分化細胞用培地、幹細胞からの分化細胞の製造及び該分化細胞を含む細胞医薬組成物の製造のための方法
RU2588666C1 (ru) * 2015-03-23 2016-07-10 Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский и технологический институт биологической промышленности" Компонент питательной среды для культивирования клеток млекопитающих
US20190300857A1 (en) * 2016-10-17 2019-10-03 Keio University Undifferentiated stem cell-removing agent, and method for removing undifferentiated stem cells

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AU2017346898A1 (en) 2019-05-02
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KR20190052096A (ko) 2019-05-15
AU2017346898B2 (en) 2021-04-01
WO2018074457A1 (ja) 2018-04-26
IL265980A (en) 2019-06-30
RU2735247C1 (ru) 2020-10-29
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