SG11201901374WA - Antibiotic compounds - Google Patents

Antibiotic compounds

Info

Publication number
SG11201901374WA
SG11201901374WA SG11201901374WA SG11201901374WA SG11201901374WA SG 11201901374W A SG11201901374W A SG 11201901374WA SG 11201901374W A SG11201901374W A SG 11201901374WA SG 11201901374W A SG11201901374W A SG 11201901374WA SG 11201901374W A SG11201901374W A SG 11201901374WA
Authority
SG
Singapore
Prior art keywords
international
compounds
merrifield
lane
centre
Prior art date
Application number
SG11201901374WA
Other languages
English (en)
Inventor
Dr Paul Meo
Dr Nawaz Khan
Original Assignee
Discuva Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Discuva Ltd filed Critical Discuva Ltd
Publication of SG11201901374WA publication Critical patent/SG11201901374WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433Thidiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5355Non-condensed oxazines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201901374WA 2016-08-22 2017-08-22 Antibiotic compounds SG11201901374WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1614314.1A GB201614314D0 (en) 2016-08-22 2016-08-22 Antibiotic compounds
PCT/GB2017/052478 WO2018037223A1 (en) 2016-08-22 2017-08-22 Antibiotic compounds

Publications (1)

Publication Number Publication Date
SG11201901374WA true SG11201901374WA (en) 2019-03-28

Family

ID=57045563

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201901374WA SG11201901374WA (en) 2016-08-22 2017-08-22 Antibiotic compounds

Country Status (15)

Country Link
US (1) US20190194179A1 (https=)
EP (1) EP3500567A1 (https=)
JP (1) JP2019528291A (https=)
KR (1) KR20190046894A (https=)
CN (1) CN109923111A (https=)
AU (1) AU2017316742A1 (https=)
BR (1) BR112019003427A2 (https=)
CA (1) CA3034000A1 (https=)
CO (1) CO2019002624A2 (https=)
EA (1) EA201990551A1 (https=)
GB (1) GB201614314D0 (https=)
MX (1) MX2019001978A (https=)
PH (1) PH12019500360A1 (https=)
SG (1) SG11201901374WA (https=)
WO (1) WO2018037223A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7503051B2 (ja) 2018-10-11 2024-06-19 バイエル・アクチエンゲゼルシヤフト イミダゾール誘導体の製造方法
EP3636645A1 (de) 2018-10-11 2020-04-15 Bayer Aktiengesellschaft Verfahren zur herstellung schwefel-substituierter pyridinderivate
TWI841671B (zh) 2019-01-24 2024-05-11 日商第一三共股份有限公司 具有取代基之脲化合物
US20220125763A1 (en) 2019-02-22 2022-04-28 Anifera Limited Compositions providing enhanced antibacterial activity against gram-positive bacteria and use thereof
CN111808093B (zh) * 2019-04-12 2023-05-16 中国医学科学院医药生物技术研究所 一种新德里金属-β-内酰胺酶-1抑制剂
WO2020210339A1 (en) 2019-04-12 2020-10-15 Mitobridge, Inc. Hmox1 inducers
US12528798B2 (en) 2019-10-29 2026-01-20 Lg Chem, Ltd. Compound for crop protectant
WO2022108354A1 (ko) * 2020-11-19 2022-05-27 주식회사 에이엔제이사이언스 신규 화합물, 이의 제조방법 및 이를 포함하는 항생제 조성물
CN113185475A (zh) * 2021-04-29 2021-07-30 江苏永凯化学有限公司 一种高效低污染的精恶唑禾草灵生产工艺
CN117043141A (zh) * 2021-05-31 2023-11-10 江苏亚虹医药科技股份有限公司 7-硝基-8-羟基喹啉衍生物、其制备方法及其医药用途
KR102754999B1 (ko) * 2022-01-06 2025-01-21 충남대학교산학협력단 신규한 화합물 및 이를 포함하는 결핵균 또는 비결핵항산균 감염질환 치료용 약제학적 조성물
WO2023234970A1 (en) * 2022-06-01 2023-12-07 KUDA Therapeutics, Inc. Imidazopyridine and oxazolopyridine derivatives and analogs thereof, methods of preparation thereof, methods of hif-1/2a pathway inhibition, and induction of ferroptosis
WO2024130173A1 (en) * 2022-12-16 2024-06-20 Immvention Therapeutix Benzimidazole derivatives
KR102840252B1 (ko) * 2023-04-27 2025-07-30 한국화학연구원 시아노벤즈이미다졸 유도체, 약제학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 약제학적 조성물
CN117003710A (zh) * 2023-07-19 2023-11-07 镇江先锋植保科技有限公司 一种2-巯基-6-氯苯并恶唑的制备方法
CN121889378A (zh) * 2023-09-01 2026-04-17 英孚欣治疗生物技术公司 取代的苯并噁唑基氨基苯并噁唑

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8604217B2 (en) * 2009-11-12 2013-12-10 Selvita S.A. Compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent
JP5786402B2 (ja) * 2011-03-29 2015-09-30 コニカミノルタ株式会社 光学フィルム、及びそれを用いた偏光板、液晶表示装置
WO2016039939A1 (en) * 2014-09-09 2016-03-17 Ptc Therapeutics, Inc. Bicyclic and tricyclic substituted 2-pyridinone antibacterial compounds

Also Published As

Publication number Publication date
WO2018037223A1 (en) 2018-03-01
CA3034000A1 (en) 2018-03-01
EP3500567A1 (en) 2019-06-26
AU2017316742A1 (en) 2019-04-11
CO2019002624A2 (es) 2019-05-31
KR20190046894A (ko) 2019-05-07
JP2019528291A (ja) 2019-10-10
US20190194179A1 (en) 2019-06-27
MX2019001978A (es) 2019-08-01
BR112019003427A2 (pt) 2019-05-21
GB201614314D0 (en) 2016-10-05
PH12019500360A1 (en) 2019-11-11
CN109923111A (zh) 2019-06-21
EA201990551A1 (ru) 2019-12-30

Similar Documents

Publication Publication Date Title
SG11201901374WA (en) Antibiotic compounds
SG11201811431VA (en) Multispecific antibodies against cd40 and cd137
SG11201805940QA (en) Benzopyrazole compounds and analogues thereof
SG11202000266VA (en) Quinoline derivatives for treating infections with helminths
SG11201809344QA (en) Process for synthesizing 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)-pyridin-3-yl)methoxy)benzaldehyde
SG11201909960UA (en) Methods for improving memory and cognition and for treating memory and cognitive disorders
SG11201811432WA (en) Rna for cancer therapy
SG11201807437XA (en) Antibodies specific to human poliovirus receptor (pvr)
SG11201908919XA (en) Combination therapies targeting pd-1, tim-3, and lag-3
SG11201809470RA (en) Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseases in animals
SG11201811221XA (en) Imidazo[1,2-a]pyridine derivatives, methods for preparing the same and use thereof
SG11201809908TA (en) Stabilized glycopeptide antibiotic formulations
SG11201806868TA (en) Compositions and methods for protecting against airborne pathogens and irritants
SG11201811442UA (en) Formulation of a peptide vaccine
SG11201909841RA (en) Antitumoral compounds
SG11201906436VA (en) Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same
SG11201810965YA (en) 1h-pyrazolo[4,3-b]pyridines as pde1 inhibitors
SG11201809537VA (en) Urea motif containing compounds and derivatives thereof as antibacterial drugs
SG11201809875VA (en) Compositions and methods for treating spinal muscular atrophy
SG11201805649UA (en) Therapeutic anti-cd9 antibody
SG11201805149XA (en) Compositions comprising 15-hepe and methods of using the same
SG11201805001UA (en) Method of treating influenza a
SG11201811345TA (en) Combination of ceftibuten and clavulanic acid for use in the treatment of bacterial infections
SG11201803643TA (en) Virulence attenuated bacteria for treatment of malignant solid tumors
SG11201807963WA (en) Compositions useful in the prevention and/or treatment of disorders of the oral cavity, upper airways and esophagus