EA201990551A1 - Антибиотические соединения - Google Patents
Антибиотические соединенияInfo
- Publication number
- EA201990551A1 EA201990551A1 EA201990551A EA201990551A EA201990551A1 EA 201990551 A1 EA201990551 A1 EA 201990551A1 EA 201990551 A EA201990551 A EA 201990551A EA 201990551 A EA201990551 A EA 201990551A EA 201990551 A1 EA201990551 A1 EA 201990551A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- compounds
- antibiotic compounds
- gram
- infection
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Изобретение относится к антибиотическим соединениям формулы (I), к композициям, содержащим данные соединения, и способам лечения бактериальных заболеваний и инфекций. Соединения находят применение в лечении инфекции и заболевания, вызванного грамположительными и/или грамотрицательными бактериями, и, в частности, в лечении инфекции и заболевания, вызванного Neisseria gonorrhoeae.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1614314.1A GB201614314D0 (en) | 2016-08-22 | 2016-08-22 | Antibiotic compounds |
PCT/GB2017/052478 WO2018037223A1 (en) | 2016-08-22 | 2017-08-22 | Antibiotic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201990551A1 true EA201990551A1 (ru) | 2019-12-30 |
Family
ID=57045563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201990551A EA201990551A1 (ru) | 2016-08-22 | 2017-08-22 | Антибиотические соединения |
Country Status (15)
Country | Link |
---|---|
US (1) | US20190194179A1 (ru) |
EP (1) | EP3500567A1 (ru) |
JP (1) | JP2019528291A (ru) |
KR (1) | KR20190046894A (ru) |
CN (1) | CN109923111A (ru) |
AU (1) | AU2017316742A1 (ru) |
BR (1) | BR112019003427A2 (ru) |
CA (1) | CA3034000A1 (ru) |
CO (1) | CO2019002624A2 (ru) |
EA (1) | EA201990551A1 (ru) |
GB (1) | GB201614314D0 (ru) |
MX (1) | MX2019001978A (ru) |
PH (1) | PH12019500360A1 (ru) |
SG (1) | SG11201901374WA (ru) |
WO (1) | WO2018037223A1 (ru) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI820232B (zh) | 2018-10-11 | 2023-11-01 | 德商拜耳廠股份有限公司 | 用於製備咪唑衍生物之方法 |
EP3636645A1 (de) | 2018-10-11 | 2020-04-15 | Bayer Aktiengesellschaft | Verfahren zur herstellung schwefel-substituierter pyridinderivate |
BR112021014539A2 (pt) | 2019-01-24 | 2021-10-13 | Daiichi Sankyo Company, Limited | Composto, ativador sirt6, composição farmacêutica, método para tratar e/ou prevenir uma doença inflamatória periférica e uso do composto |
JP2022521339A (ja) * | 2019-02-22 | 2022-04-06 | アニフェラ・リミテッド | グラム陽性菌に対して向上された抗菌活性を提供する組成物およびその使用 |
EP3952990A1 (en) * | 2019-04-12 | 2022-02-16 | Mitobridge, Inc. | Hmox1 inducers |
CN111808093B (zh) * | 2019-04-12 | 2023-05-16 | 中国医学科学院医药生物技术研究所 | 一种新德里金属-β-内酰胺酶-1抑制剂 |
CN113185475A (zh) * | 2021-04-29 | 2021-07-30 | 江苏永凯化学有限公司 | 一种高效低污染的精恶唑禾草灵生产工艺 |
WO2023234970A1 (en) * | 2022-06-01 | 2023-12-07 | KUDA Therapeutics, Inc. | Imidazopyridine and oxazolopyridine derivatives and analogs thereof, methods of preparation thereof, methods of hif-1/2a pathway inhibition, and induction of ferroptosis |
CN117003710A (zh) * | 2023-07-19 | 2023-11-07 | 镇江先锋植保科技有限公司 | 一种2-巯基-6-氯苯并恶唑的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8604217B2 (en) * | 2009-11-12 | 2013-12-10 | Selvita S.A. | Compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent |
JP5786402B2 (ja) * | 2011-03-29 | 2015-09-30 | コニカミノルタ株式会社 | 光学フィルム、及びそれを用いた偏光板、液晶表示装置 |
WO2016039939A1 (en) * | 2014-09-09 | 2016-03-17 | Ptc Therapeutics, Inc. | Bicyclic and tricyclic substituted 2-pyridinone antibacterial compounds |
-
2016
- 2016-08-22 GB GBGB1614314.1A patent/GB201614314D0/en not_active Ceased
-
2017
- 2017-08-22 EA EA201990551A patent/EA201990551A1/ru unknown
- 2017-08-22 US US16/327,286 patent/US20190194179A1/en not_active Abandoned
- 2017-08-22 BR BR112019003427-7A patent/BR112019003427A2/pt not_active Application Discontinuation
- 2017-08-22 CN CN201780063473.8A patent/CN109923111A/zh active Pending
- 2017-08-22 CA CA3034000A patent/CA3034000A1/en not_active Abandoned
- 2017-08-22 MX MX2019001978A patent/MX2019001978A/es unknown
- 2017-08-22 SG SG11201901374WA patent/SG11201901374WA/en unknown
- 2017-08-22 WO PCT/GB2017/052478 patent/WO2018037223A1/en unknown
- 2017-08-22 JP JP2019510688A patent/JP2019528291A/ja not_active Withdrawn
- 2017-08-22 EP EP17761308.0A patent/EP3500567A1/en not_active Withdrawn
- 2017-08-22 KR KR1020197008269A patent/KR20190046894A/ko not_active Application Discontinuation
- 2017-08-22 AU AU2017316742A patent/AU2017316742A1/en not_active Withdrawn
-
2019
- 2019-02-20 PH PH12019500360A patent/PH12019500360A1/en unknown
- 2019-03-21 CO CONC2019/0002624A patent/CO2019002624A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
CN109923111A (zh) | 2019-06-21 |
SG11201901374WA (en) | 2019-03-28 |
EP3500567A1 (en) | 2019-06-26 |
BR112019003427A2 (pt) | 2019-05-21 |
CO2019002624A2 (es) | 2019-05-31 |
WO2018037223A1 (en) | 2018-03-01 |
US20190194179A1 (en) | 2019-06-27 |
AU2017316742A1 (en) | 2019-04-11 |
GB201614314D0 (en) | 2016-10-05 |
JP2019528291A (ja) | 2019-10-10 |
PH12019500360A1 (en) | 2019-11-11 |
MX2019001978A (es) | 2019-08-01 |
CA3034000A1 (en) | 2018-03-01 |
KR20190046894A (ko) | 2019-05-07 |
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