SG11201900947RA - Tlr7/8 antagonists and uses thereof - Google Patents

Tlr7/8 antagonists and uses thereof

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Publication number
SG11201900947RA
SG11201900947RA SG11201900947RA SG11201900947RA SG11201900947RA SG 11201900947R A SG11201900947R A SG 11201900947RA SG 11201900947R A SG11201900947R A SG 11201900947RA SG 11201900947R A SG11201900947R A SG 11201900947RA SG 11201900947R A SG11201900947R A SG 11201900947RA
Authority
SG
Singapore
Prior art keywords
international
massachusetts
pct
tlr7
antagonists
Prior art date
Application number
SG11201900947RA
Other languages
English (en)
Inventor
Brian A Sherer
Xiaoling Chen
Esther Cleary
Nadia Brugger
Original Assignee
Merck Patent Gmbh
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Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SG11201900947RA publication Critical patent/SG11201900947RA/en

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    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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    • A61K31/53751,4-Oxazines, e.g. morpholine
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US201662371917P 2016-08-08 2016-08-08
PCT/US2017/045671 WO2018031434A1 (en) 2016-08-08 2017-08-07 Tlr7/8 antagonists and uses thereof

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