SG11201811159SA - Methods for multi-resolution analysis of cell-free nucleic acids - Google Patents
Methods for multi-resolution analysis of cell-free nucleic acidsInfo
- Publication number
- SG11201811159SA SG11201811159SA SG11201811159SA SG11201811159SA SG11201811159SA SG 11201811159S A SG11201811159S A SG 11201811159SA SG 11201811159S A SG11201811159S A SG 11201811159SA SG 11201811159S A SG11201811159S A SG 11201811159SA SG 11201811159S A SG11201811159S A SG 11201811159SA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- cell
- genomic regions
- pct
- regions
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/30—Unsupervised data analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/159—Reduction of complexity, e.g. amplification of subsets, removing duplicated genomic regions
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Data Mining & Analysis (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Artificial Intelligence (AREA)
- Bioethics (AREA)
- Physiology (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Evolutionary Computation (AREA)
- Public Health (AREA)
- Software Systems (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662402940P | 2016-09-30 | 2016-09-30 | |
| US201762468201P | 2017-03-07 | 2017-03-07 | |
| US201762489391P | 2017-04-24 | 2017-04-24 | |
| PCT/US2017/054607 WO2018064629A1 (en) | 2016-09-30 | 2017-09-29 | Methods for multi-resolution analysis of cell-free nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201811159SA true SG11201811159SA (en) | 2019-01-30 |
Family
ID=61760169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201811159SA SG11201811159SA (en) | 2016-09-30 | 2017-09-29 | Methods for multi-resolution analysis of cell-free nucleic acids |
Country Status (10)
| Country | Link |
|---|---|
| US (7) | US20200013482A1 (ja) |
| EP (2) | EP3792922A1 (ja) |
| JP (5) | JP6560465B1 (ja) |
| KR (2) | KR20210158870A (ja) |
| CN (1) | CN109642250A (ja) |
| AU (2) | AU2017336153B2 (ja) |
| CA (2) | CA3027919C (ja) |
| ES (1) | ES2840003T3 (ja) |
| SG (1) | SG11201811159SA (ja) |
| WO (1) | WO2018064629A1 (ja) |
Families Citing this family (13)
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| PL2697397T3 (pl) | 2011-04-15 | 2017-08-31 | The Johns Hopkins University | System bezpiecznego sekwencjonowania |
| US11525163B2 (en) | 2012-10-29 | 2022-12-13 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| CN115044645A (zh) | 2015-11-11 | 2022-09-13 | 分析生物科学有限公司 | Dna文库的高效率构建 |
| WO2017181146A1 (en) | 2016-04-14 | 2017-10-19 | Guardant Health, Inc. | Methods for early detection of cancer |
| US20190287645A1 (en) * | 2016-07-06 | 2019-09-19 | Guardant Health, Inc. | Methods for fragmentome profiling of cell-free nucleic acids |
| RU2019108294A (ru) | 2016-08-25 | 2020-09-25 | Резолюшн Байосайенс, Инк. | Способы обнаружения изменений количества геномных копий в образцах днк |
| ES2840003T3 (es) | 2016-09-30 | 2021-07-06 | Guardant Health Inc | Métodos para análisis multi-resolución de ácidos nucleicos libres de células |
| JP7232476B2 (ja) | 2017-08-07 | 2023-03-08 | ザ ジョンズ ホプキンス ユニバーシティ | がんを評価及び治療するための方法及び物質 |
| US20210155992A1 (en) * | 2018-04-16 | 2021-05-27 | Memorial Sloan Kettering Cancer Center | SYSTEMS AND METHODS FOR DETECTING CANCER VIA cfDNA SCREENING |
| WO2023282916A1 (en) | 2021-07-09 | 2023-01-12 | Guardant Health, Inc. | Methods of detecting genomic rearrangements using cell free nucleic acids |
| EP4205126A1 (en) | 2020-08-25 | 2023-07-05 | Guardant Health, Inc. | Methods and systems for predicting an origin of a variant |
| CN117935921A (zh) * | 2024-03-21 | 2024-04-26 | 北京贝瑞和康生物技术有限公司 | 确定缺失/重复类型的方法、设备、介质和程序产品 |
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| US20170058332A1 (en) | 2015-09-02 | 2017-03-02 | Guardant Health, Inc. | Identification of somatic mutations versus germline variants for cell-free dna variant calling applications |
| JP6991134B2 (ja) | 2015-10-09 | 2022-01-12 | ガーダント ヘルス， インコーポレイテッド | 無細胞ｄｎａを使用する集団ベースの処置レコメンダ |
| EP3359695B1 (en) | 2015-10-10 | 2020-04-15 | Guardant Health, Inc. | Methods and applications of gene fusion detection in cell-free dna analysis |
| CN108603228B (zh) | 2015-12-17 | 2023-09-01 | 夸登特健康公司 | 通过分析无细胞dna确定肿瘤基因拷贝数的方法 |
| CA3013366A1 (en) | 2016-02-02 | 2017-08-10 | Guardant Health, Inc. | Cancer evolution detection and diagnostic |
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2017
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