SG11201908319WA - Methods and systems for printing biological material - Google Patents

Methods and systems for printing biological material

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Publication number
SG11201908319WA
SG11201908319WA SG11201908319WA SG11201908319WA SG 11201908319W A SG11201908319W A SG 11201908319WA SG 11201908319W A SG11201908319W A SG 11201908319WA SG 11201908319W A SG11201908319W A SG 11201908319WA
Authority
SG
Singapore
Prior art keywords
international
biological material
printing
rule
california
Prior art date
Application number
Inventor
Melanie P Matheu
Original Assignee
Prellis Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prellis Biologics Inc filed Critical Prellis Biologics Inc
Publication of SG11201908319WA publication Critical patent/SG11201908319WA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B29C64/264Arrangements for irradiation
    • B29C64/268Arrangements for irradiation using laser beams; using electron beams [EB]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B29C64/264Arrangements for irradiation
    • B29C64/277Arrangements for irradiation using multiple radiation means, e.g. micromirrors or multiple light-emitting diodes [LED]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30Auxiliary operations or equipment
    • B29C64/386Data acquisition or data processing for additive manufacturing
    • B29C64/393Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00Data acquisition or data processing for additive manufacturing
    • B33Y50/02Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062General methods for three-dimensional culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698Skin equivalents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2529/00Culture process characterised by the use of electromagnetic stimulation
    • C12N2529/10Stimulation by light

Abstract

International Patent Classification: (71) Applicant: PRELLIS BIOLOGICS, INC. [US/US]; 953 B29C 64/393 (2017.01) Cl 2M 1/26 (2006.01) Indiana Street, San Francisco, California 94107 (US). B29C 64/268 (2017.01) Cl 2M 1/36 (2006.01) B29C 64/277 (2017.01) Cl 2N 5/00 (2006.01) (72) Inventor: MATHEU, Melanie P.; 953 Indiana Street, San C12M 3/00 (2006.01) B33Y 80/00 (2015.01) Francisco, California 94107 (US). C12M 1/12 (2006.01) B33Y 50/02 (2015.01) (74) Agent: ALMEDA, Dariela; WILSON SONSINI (21) International Application Number: PCT/US2018/021850 (22) International Filing Date: 09 March 2018 (09.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/469,948 10 March 2017 (10.03.2017) US GOODRICH & ROSATI, 650 Page Mill Road, Palo Alto, California 94304 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, FIG, 44 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 13 September 2018 (13.09.2018) WIP0 I PCT 0111111010 0111 °nolo mu Kim offiniou oimIE (10) International Publication Number WO 2018/165613 Al (54) Title: METHODS AND SYSTEMS FOR PRINTING BIOLOGICAL MATERIAL (57) : The present disclosure provides methods and systems for printing a three-dimensional (3D) material. In some examples, a method for printing a 3D biological material comprises providing a media chamber comprising a medium comprising (i) a plurality of cells and (ii) one or more polymer precursors. Next, at least one energy beam may be directed to the medium in the media chamber along at least one energy beam path that is patterned into a 3D projection wherein the x, y, and z dimensions may be simultaneously accessed in accordance with computer instructions for printing the 3D biological material in computer memory, to form at least a portion of the 3D biological material comprising (i) at least a subset of the plurality of cells, and (ii) a polymer formed from the one or more polymer precursors. [Continued on next page] WO 2018/165613 Al MIDEDIMOMOIDEIREEMOMMEMERMOMMOVOIS SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(11)) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))
SG11201908319W 2017-03-10 2018-03-09 Methods and systems for printing biological material SG11201908319WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762469948P 2017-03-10 2017-03-10
PCT/US2018/021850 WO2018165613A1 (en) 2017-03-10 2018-03-09 Methods and systems for printing biological material

Publications (1)

Publication Number Publication Date
SG11201908319WA true SG11201908319WA (en) 2019-10-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201908319W SG11201908319WA (en) 2017-03-10 2018-03-09 Methods and systems for printing biological material

Country Status (10)

Country Link
EP (1) EP3592535A4 (en)
JP (1) JP7401311B2 (en)
CN (1) CN110612194A (en)
AU (1) AU2018231122B2 (en)
BR (1) BR112019018778A2 (en)
CA (1) CA3055927A1 (en)
GB (2) GB2576985B (en)
MX (1) MX2019010716A (en)
SG (1) SG11201908319WA (en)
WO (1) WO2018165613A1 (en)

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US10933579B2 (en) 2017-03-10 2021-03-02 Prellis Biologics, Inc. Methods and systems for printing biological material
US11085018B2 (en) 2017-03-10 2021-08-10 Prellis Biologics, Inc. Three-dimensional printed organs, devices, and matrices
JP2020524483A (en) 2017-05-25 2020-08-20 プレリス バイオロジクス,インク. Three-dimensional printed organs, devices, and matrices
CN112955306B (en) * 2018-07-31 2023-12-22 普瑞利思生物制品公司 Three-dimensional printing method and system
US20220088872A1 (en) * 2019-01-14 2022-03-24 Arizona Board Of Regents On Behalf Of The University Of Arizona High resolution, high throughput additive manufacturing
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US20220243171A1 (en) * 2019-07-01 2022-08-04 University Of Florida Research Foundation, Inc. Systems and methods relating to three-dimensional (3d) cell manufacturing
WO2021007359A1 (en) * 2019-07-08 2021-01-14 Meatech 3D, Ltd. Cultured edible meat fabrication using bio-printing
US20210041853A1 (en) * 2019-08-06 2021-02-11 Emory University Systems, Devices, and Methods for Generating a Model of a Vascular Network, and for Analyzing and/or Treatment Planning Related to Thereof
GB202211759D0 (en) * 2020-01-14 2022-09-28 Prellis Biologics Inc Methods and systems for model generation
JP2021137792A (en) * 2020-03-09 2021-09-16 株式会社リコー Liquid droplet discharging method, method for manufacturing container including tissue body, and liquid droplet discharging apparatus
AU2021243961A1 (en) * 2020-03-22 2022-11-24 Collplant Ltd. Collagen-based formulations usable as soft tissue fillers and/or implants
US11153556B1 (en) 2020-03-31 2021-10-19 Toyota Motor Engineering & Manufacturing North America, Inc. Volumetric accessing of a volumetric display
CN112172144A (en) * 2020-10-10 2021-01-05 西南医科大学 Biological 3D printing device with clean sterilization and temperature control functions
CN112519223B (en) * 2020-11-17 2022-12-23 天津滨海雷克斯激光科技发展有限公司 Intelligent adjustment laser processing head of additive manufacturing equipment
CN112893764B (en) * 2021-01-21 2022-04-12 大连理工大学 3D printing coated silica sand for optical fiber laser processing and preparation method thereof
CN113334763A (en) * 2021-05-24 2021-09-03 上海大学 Biological tissue micro-unit forming system and method
CN113655026B (en) * 2021-08-05 2024-01-23 中国科学院苏州生物医学工程技术研究所 Elliptic hemispherical surface large-view high-flux two-photon microscope
CN114851550A (en) * 2022-04-19 2022-08-05 广州医科大学 Volume three-dimensional biological printing device and printing method
WO2023235758A1 (en) * 2022-06-01 2023-12-07 Brian Hachtmann Methods and systems for three-dimensional printing

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Also Published As

Publication number Publication date
GB2602614A (en) 2022-07-06
AU2018231122B2 (en) 2023-12-21
WO2018165613A1 (en) 2018-09-13
JP7401311B2 (en) 2023-12-19
GB201913615D0 (en) 2019-11-06
EP3592535A4 (en) 2020-12-30
EP3592535A1 (en) 2020-01-15
BR112019018778A2 (en) 2020-04-07
CA3055927A1 (en) 2018-09-13
CN110612194A (en) 2019-12-24
JP2020511158A (en) 2020-04-16
AU2018231122A1 (en) 2019-10-10
GB2576985B (en) 2023-01-18
MX2019010716A (en) 2020-02-12
GB2576985A (en) 2020-03-11
GB2602614B (en) 2023-02-15

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