SG11201700880RA - Modified nucleotide linkers - Google Patents
Modified nucleotide linkersInfo
- Publication number
- SG11201700880RA SG11201700880RA SG11201700880RA SG11201700880RA SG11201700880RA SG 11201700880R A SG11201700880R A SG 11201700880RA SG 11201700880R A SG11201700880R A SG 11201700880RA SG 11201700880R A SG11201700880R A SG 11201700880RA SG 11201700880R A SG11201700880R A SG 11201700880RA
- Authority
- SG
- Singapore
- Prior art keywords
- modified nucleotide
- nucleotide linkers
- linkers
- modified
- nucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1414098.2A GB201414098D0 (en) | 2014-08-08 | 2014-08-08 | Modified nucleotide linkers |
| PCT/GB2015/052282 WO2016020691A1 (en) | 2014-08-08 | 2015-08-06 | Modified nucleotide linkers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201700880RA true SG11201700880RA (en) | 2017-03-30 |
Family
ID=51629525
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201700880RA SG11201700880RA (en) | 2014-08-08 | 2015-08-06 | Modified nucleotide linkers |
| SG10201900948PA SG10201900948PA (en) | 2014-08-08 | 2015-08-06 | Modified nucleotide linkers |
| SG10202000850XA SG10202000850XA (en) | 2014-08-08 | 2015-08-06 | Modified nucleotide linkers |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201900948PA SG10201900948PA (en) | 2014-08-08 | 2015-08-06 | Modified nucleotide linkers |
| SG10202000850XA SG10202000850XA (en) | 2014-08-08 | 2015-08-06 | Modified nucleotide linkers |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US10190157B2 (enExample) |
| EP (2) | EP3564252B1 (enExample) |
| JP (3) | JP6563482B2 (enExample) |
| KR (2) | KR102287718B1 (enExample) |
| CN (2) | CN106604926B (enExample) |
| AU (2) | AU2015298469B2 (enExample) |
| BR (2) | BR122020018717B1 (enExample) |
| CA (1) | CA2957382C (enExample) |
| DK (2) | DK3564252T3 (enExample) |
| ES (2) | ES2773438T3 (enExample) |
| GB (1) | GB201414098D0 (enExample) |
| IL (1) | IL250498B (enExample) |
| MX (2) | MX385213B (enExample) |
| MY (1) | MY195167A (enExample) |
| NZ (2) | NZ728810A (enExample) |
| RU (1) | RU2699993C2 (enExample) |
| SG (3) | SG11201700880RA (enExample) |
| WO (1) | WO2016020691A1 (enExample) |
| ZA (1) | ZA201700838B (enExample) |
Families Citing this family (51)
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|---|---|---|---|---|
| GB201414098D0 (en) | 2014-08-08 | 2014-09-24 | Illumina Cambridge Ltd | Modified nucleotide linkers |
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| CN108779138B (zh) | 2015-09-28 | 2022-06-17 | 哥伦比亚大学董事会 | 用作dna合成测序的可逆终止物的基于新的二硫键接头的核苷酸的设计与合成 |
| CN109661232B (zh) | 2016-05-23 | 2023-03-03 | 纽约哥伦比亚大学董事会 | 核苷酸衍生物及其使用方法 |
| MY203439A (en) * | 2016-12-22 | 2024-06-28 | Illumina Inc | Array including sequencing primer and non-sequencing entity |
| US11591647B2 (en) | 2017-03-06 | 2023-02-28 | Singular Genomics Systems, Inc. | Nucleic acid sequencing-by-synthesis (SBS) methods that combine SBS cycle steps |
| EP3600339A4 (en) | 2017-03-28 | 2021-05-19 | The Trustees of Columbia University in the City of New York | 3'-O-MODIFIED NUCLEOTIDE ANALOGUE WITH DIFFERENT FITTING LINKS TO FIX FLUORESCENT MARKERS TO THE BASE FOR DNA SEQUENCING BY SYNTHESIS |
| CN110650968B (zh) * | 2017-10-11 | 2022-07-05 | 深圳华大智造科技股份有限公司 | 修饰的核苷或核苷酸 |
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| WO2019178393A1 (en) | 2018-03-15 | 2019-09-19 | The Trustees Of Columbia University In The City Of New York | Nucleotide analogues and use thereof for nucleic acid sequencing and analysis |
| CN113039191B (zh) | 2018-10-25 | 2024-07-16 | 奇异基因组学系统公司 | 核苷酸类似物 |
| AU2019400090B2 (en) * | 2018-12-14 | 2025-11-27 | Illumina Cambridge Limited | Decreasing phasing with unlabeled nucleotides during sequencing |
| US11293061B2 (en) | 2018-12-26 | 2022-04-05 | Illumina Cambridge Limited | Sequencing methods using nucleotides with 3′ AOM blocking group |
| US11970735B2 (en) | 2019-01-08 | 2024-04-30 | Singular Genomics Systems, Inc. | Nucleotide cleavable linkers and uses thereof |
| BR112020026669A2 (pt) | 2019-03-01 | 2021-09-08 | Illumina Cambridge Limited | Composto de cumarina substituído com amina terciária, nucleotídeos ou oligonucleotídeos, kit, uso dos mesmos, método de sequenciamento e método para sintetizar um composto |
| WO2020178231A1 (en) | 2019-03-01 | 2020-09-10 | Illumina, Inc. | Multiplexed fluorescent detection of analytes |
| NL2023327B1 (en) | 2019-03-01 | 2020-09-17 | Illumina Inc | Multiplexed fluorescent detection of analytes |
| IL279674B2 (en) | 2019-03-01 | 2025-04-01 | Illumina Cambridge Ltd | Amine-modified exocyclic coumarins and their use as fluorescent tags |
| US11421271B2 (en) | 2019-03-28 | 2022-08-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing using photoswitchable labels |
| MX2022005327A (es) | 2019-11-27 | 2022-08-04 | Illumina Cambridge Ltd | Tintes y composiciones que contienen ciclooctatetraeno.. |
| JP7287299B2 (ja) | 2020-01-31 | 2023-06-06 | トヨタ自動車株式会社 | 車両および車両制御インターフェース |
| US11787831B2 (en) | 2020-06-22 | 2023-10-17 | Illumina Cambridge Limited | Nucleosides and nucleotides with 3′ acetal blocking group |
| US11981964B2 (en) | 2020-07-28 | 2024-05-14 | Illumina Cambridge Limited | Substituted coumarin dyes and uses as fluorescent labels |
| US20220195196A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Alkylpyridinium coumarin dyes and uses in sequencing applications |
| US20220195517A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Long stokes shift chromenoquinoline dyes and uses in sequencing applications |
| US20220195516A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Methods, systems and compositions for nucleic acid sequencing |
| US20220195518A1 (en) | 2020-12-22 | 2022-06-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing |
| KR102884006B1 (ko) | 2021-05-05 | 2025-11-10 | 일루미나 케임브리지 리미티드 | 비스-붕소 융합 헤테로사이클을 함유하는 형광 염료 및 서열분석에서의 용도 |
| BR112023024130A2 (pt) | 2021-05-20 | 2024-01-30 | Illumina Cambridge Ltd | Composições e métodos para sequenciamento por síntese |
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