MX385213B - Ligadores de nucleótidos modificados. - Google Patents
Ligadores de nucleótidos modificados.Info
- Publication number
- MX385213B MX385213B MX2020009401A MX2020009401A MX385213B MX 385213 B MX385213 B MX 385213B MX 2020009401 A MX2020009401 A MX 2020009401A MX 2020009401 A MX2020009401 A MX 2020009401A MX 385213 B MX385213 B MX 385213B
- Authority
- MX
- Mexico
- Prior art keywords
- modified nucleotide
- linkets
- linkers
- nucleotide linkers
- sequencing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La presente invención se refiere a nuevos enlazadores de nucleótido modificados para incrementar la eficiencia de la incorporación de nucleótido en secuenciar mediante aplicaciones de síntesis. También se proporcionan métodos para preparar estos enlazadores de nucleótido modificados con los mismos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1414098.2A GB201414098D0 (en) | 2014-08-08 | 2014-08-08 | Modified nucleotide linkers |
| PCT/GB2015/052282 WO2016020691A1 (en) | 2014-08-08 | 2015-08-06 | Modified nucleotide linkers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2020009401A MX2020009401A (es) | 2021-08-09 |
| MX385213B true MX385213B (es) | 2025-03-14 |
Family
ID=51629525
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020009401A MX385213B (es) | 2014-08-08 | 2015-08-06 | Ligadores de nucleótidos modificados. |
| MX2017001694A MX377448B (es) | 2014-08-08 | 2015-08-06 | Ligadores de nucleotidos modificados. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017001694A MX377448B (es) | 2014-08-08 | 2015-08-06 | Ligadores de nucleotidos modificados. |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US10190157B2 (es) |
| EP (2) | EP3564252B1 (es) |
| JP (3) | JP6563482B2 (es) |
| KR (2) | KR102287718B1 (es) |
| CN (2) | CN106604926B (es) |
| AU (2) | AU2015298469B2 (es) |
| BR (2) | BR122020018717B1 (es) |
| CA (1) | CA2957382C (es) |
| DK (2) | DK3564252T3 (es) |
| ES (2) | ES2773438T3 (es) |
| GB (1) | GB201414098D0 (es) |
| IL (1) | IL250498B (es) |
| MX (2) | MX385213B (es) |
| MY (1) | MY195167A (es) |
| NZ (1) | NZ728810A (es) |
| RU (1) | RU2699993C2 (es) |
| SG (3) | SG10202000850XA (es) |
| WO (1) | WO2016020691A1 (es) |
| ZA (1) | ZA201700838B (es) |
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| WO2017058953A1 (en) | 2015-09-28 | 2017-04-06 | The Trustees Of Columbia University In The City Of New York | Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis |
| CN116656795A (zh) | 2016-05-23 | 2023-08-29 | 纽约哥伦比亚大学董事会 | 核苷酸衍生物及其使用方法 |
| MY203439A (en) * | 2016-12-22 | 2024-06-28 | Illumina Inc | Array including sequencing primer and non-sequencing entity |
| EP3596099B1 (en) | 2017-03-06 | 2024-07-24 | Singular Genomics Systems, Inc. | Nucleic acid sequencing-by-synthesis (sbs) methods that combine sbs cycle steps |
| CN119639879A (zh) | 2017-03-28 | 2025-03-18 | 哥伦比亚大学董事会 | 用于连接荧光标记与用于dna合成测序的碱基的具有不同可裂解连接子的3'-o-改性的核苷酸类似物 |
| CN110650968B (zh) * | 2017-10-11 | 2022-07-05 | 深圳华大智造科技股份有限公司 | 修饰的核苷或核苷酸 |
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| US12188086B2 (en) | 2018-03-15 | 2025-01-07 | The Trustees Of Columbia University In The City Of New York | Nucleotide analogues and use thereof for nucleic acid sequencing and analysis preliminary class |
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