MX377448B - Ligadores de nucleotidos modificados. - Google Patents
Ligadores de nucleotidos modificados.Info
- Publication number
- MX377448B MX377448B MX2017001694A MX2017001694A MX377448B MX 377448 B MX377448 B MX 377448B MX 2017001694 A MX2017001694 A MX 2017001694A MX 2017001694 A MX2017001694 A MX 2017001694A MX 377448 B MX377448 B MX 377448B
- Authority
- MX
- Mexico
- Prior art keywords
- modified nucleotide
- nucleotide linkers
- linkers
- preparing
- increasing
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 238000012163 sequencing technique Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Algunas modalidades de la presente solicitud se refieren a nuevos enlazadores de nucleótido modificados para incrementar la eficiencia de la incorporación de nucleótido en secuenciar mediante aplicaciones de síntesis. También se proporcionan métodos para preparar estos enlazadores de nucleótido modificados con los mismos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1414098.2A GB201414098D0 (en) | 2014-08-08 | 2014-08-08 | Modified nucleotide linkers |
| PCT/GB2015/052282 WO2016020691A1 (en) | 2014-08-08 | 2015-08-06 | Modified nucleotide linkers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2017001694A MX2017001694A (es) | 2017-04-27 |
| MX377448B true MX377448B (es) | 2025-03-10 |
Family
ID=51629525
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020009401A MX385213B (es) | 2014-08-08 | 2015-08-06 | Ligadores de nucleótidos modificados. |
| MX2017001694A MX377448B (es) | 2014-08-08 | 2015-08-06 | Ligadores de nucleotidos modificados. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2020009401A MX385213B (es) | 2014-08-08 | 2015-08-06 | Ligadores de nucleótidos modificados. |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US10190157B2 (es) |
| EP (2) | EP3564252B1 (es) |
| JP (3) | JP6563482B2 (es) |
| KR (2) | KR102287718B1 (es) |
| CN (2) | CN111704643A (es) |
| AU (2) | AU2015298469B2 (es) |
| BR (2) | BR112017002251B1 (es) |
| CA (1) | CA2957382C (es) |
| DK (2) | DK3564252T3 (es) |
| ES (2) | ES2773438T3 (es) |
| GB (1) | GB201414098D0 (es) |
| IL (1) | IL250498B (es) |
| MX (2) | MX385213B (es) |
| MY (1) | MY195167A (es) |
| NZ (2) | NZ728810A (es) |
| RU (1) | RU2699993C2 (es) |
| SG (3) | SG10201900948PA (es) |
| WO (1) | WO2016020691A1 (es) |
| ZA (1) | ZA201700838B (es) |
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| WO2017058953A1 (en) | 2015-09-28 | 2017-04-06 | The Trustees Of Columbia University In The City Of New York | Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis |
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| KR102586847B1 (ko) * | 2016-12-22 | 2023-10-10 | 일루미나, 인코포레이티드 | 시퀀싱 프라이머 및 비-시퀀싱 존재물을 포함하는 어레이 |
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| CN110650968B (zh) * | 2017-10-11 | 2022-07-05 | 深圳华大智造科技股份有限公司 | 修饰的核苷或核苷酸 |
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