SG11201609209YA - Naphthyridinedione derivatives - Google Patents
Naphthyridinedione derivativesInfo
- Publication number
- SG11201609209YA SG11201609209YA SG11201609209YA SG11201609209YA SG11201609209YA SG 11201609209Y A SG11201609209Y A SG 11201609209YA SG 11201609209Y A SG11201609209Y A SG 11201609209YA SG 11201609209Y A SG11201609209Y A SG 11201609209YA SG 11201609209Y A SG11201609209Y A SG 11201609209YA
- Authority
- SG
- Singapore
- Prior art keywords
- naphthyridinedione
- derivatives
- naphthyridinedione derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14170976 | 2014-06-03 | ||
| PCT/IB2015/054174 WO2015186063A1 (fr) | 2014-06-03 | 2015-06-02 | Dérivés de naphthyridinédione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201609209YA true SG11201609209YA (en) | 2016-12-29 |
Family
ID=50841689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201609209YA SG11201609209YA (en) | 2014-06-03 | 2015-06-02 | Naphthyridinedione derivatives |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US10138232B2 (fr) |
| EP (1) | EP3152209B1 (fr) |
| JP (2) | JP6343034B2 (fr) |
| KR (1) | KR101905295B1 (fr) |
| CN (1) | CN106459043B (fr) |
| AP (1) | AP2016009545A0 (fr) |
| AR (1) | AR100706A1 (fr) |
| AU (2) | AU2015270125B2 (fr) |
| BR (1) | BR112016027383A8 (fr) |
| CA (1) | CA2950724A1 (fr) |
| CL (1) | CL2016003081A1 (fr) |
| CR (1) | CR20160565A (fr) |
| CU (1) | CU24438B1 (fr) |
| EA (1) | EA030374B1 (fr) |
| EC (1) | ECSP16096831A (fr) |
| ES (1) | ES2731802T3 (fr) |
| GT (1) | GT201600252A (fr) |
| IL (1) | IL248773B (fr) |
| MX (1) | MX2016015856A (fr) |
| MY (1) | MY178379A (fr) |
| PE (1) | PE20170086A1 (fr) |
| PH (2) | PH12016502293A1 (fr) |
| SG (1) | SG11201609209YA (fr) |
| SV (1) | SV2016005331A (fr) |
| TN (1) | TN2016000490A1 (fr) |
| TW (1) | TWI688565B (fr) |
| UY (1) | UY36150A (fr) |
| WO (1) | WO2015186063A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015186062A1 (fr) | 2014-06-03 | 2015-12-10 | Novartis Ag | Dérivés de pyrimido [4,5-b] quinoline -4,5 (3h,10h)-dione |
| PE20170086A1 (es) | 2014-06-03 | 2017-03-17 | Novartis Ag | Derivados de naftiridinadiona |
| JP6526064B2 (ja) * | 2014-06-03 | 2019-06-05 | ノバルティス アーゲー | ピリドピリミジンジオン誘導体 |
| WO2019225625A1 (fr) * | 2018-05-23 | 2019-11-28 | 京都薬品工業株式会社 | Inducteur de translecture et utilisation pharmaceutique associée |
| TWI840389B (zh) | 2018-07-24 | 2024-05-01 | 日商索尼半導體解決方案公司 | 半導體裝置 |
| WO2024161623A1 (fr) * | 2023-02-03 | 2024-08-08 | 株式会社 RINAT Imaging | Médicament de translecture, utilisation d'une sonde d'acide nucléique et agent de combinaison de translecture |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2884170B2 (ja) | 1989-08-24 | 1999-04-19 | 株式会社フジモト・ブラザーズ | ５−デアザフラビン系化合物を有効成分とする制癌剤 |
| JP2989871B2 (ja) * | 1989-08-30 | 1999-12-13 | 大日本製薬株式会社 | 三環式化合物 |
| DE4035479A1 (de) | 1990-11-08 | 1992-05-14 | Basf Ag | Substituierte pyrido (2,3-d)pyrimidin-2,4(1h,3h)-dione |
| WO1996028444A1 (fr) | 1995-03-15 | 1996-09-19 | Pfizer Inc. | INHIBITEURS DES TYROSINES KINASES, A BASE DE 5,10-DIHYDROPYRIMIDO[4,5-b]QUINOLINE-4(1H)-ONE |
| US6016875A (en) * | 1998-02-10 | 2000-01-25 | Case Corporation | Gain adaptation control for hydraulic systems |
| US6468990B1 (en) | 1999-05-17 | 2002-10-22 | Queen's University At Kingston | Method of inhibiting binding of nerve growth factor to p75 NTR receptor |
| WO2004006906A2 (fr) | 2002-07-15 | 2004-01-22 | Combinatorx, Incorporated | Methodes de traitement de neoplasmes |
| JP2007524596A (ja) | 2003-02-28 | 2007-08-30 | トランスフォーム・ファーマシューティカルズ・インコーポレイテッド | 共結晶医薬組成物 |
| SI3345895T1 (sl) | 2003-04-11 | 2020-03-31 | Ptc Therapeutics, Inc. | Spojina 1,2,4-oksadiazol benzojske kisline in njena uporaba za supresijo nesmiselne in zdravljenje bolezni |
| US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| BR122018075478B8 (pt) | 2004-06-24 | 2023-10-31 | Vertex Pharma | moduladores de transportadores de cassete de ligação de atp |
| CN101076332A (zh) * | 2004-10-13 | 2007-11-21 | Ptc医疗公司 | 吡唑或三唑化合物及其用于制备治疗体细胞突变相关疾病的药物的用途 |
| EP2007783B1 (fr) | 2006-04-03 | 2018-07-11 | Technion Research & Development Foundation Ltd. | Nouveaux aminoglycosides et leurs utilisations dans le traitement de troubles génétiques |
| WO2008024433A2 (fr) | 2006-08-23 | 2008-02-28 | Neurogen Corporation | Dérivés de la pyrimidinone substitués par un halogénoalkyle |
| ES2548292T3 (es) | 2007-05-25 | 2015-10-15 | Vertex Pharmaceuticals Incorporated | Moduladores del regulador de la conductancia transmembrana de la fibrosis quística |
| WO2009086303A2 (fr) | 2007-12-21 | 2009-07-09 | University Of Rochester | Procédé permettant de modifier la durée de vie d'organismes eucaryotes |
| EP2422817A1 (fr) | 2010-07-29 | 2012-02-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Conjugués flavine-ligand d'acide nucléique |
| WO2012016930A1 (fr) | 2010-08-05 | 2012-02-09 | Universite De Droit Et Sante De Lille | Composé utile pour le traitement de maladies médiées par une mutation non-sens et composition pharmaceutique comprenant ledit composé |
| CA2890692A1 (fr) | 2012-12-13 | 2014-06-19 | Novartis Ag | Pyrimido [4,5-b]quinoline-4,5 (3h,10h)-diones utilises en tant que suppresseurs de mutation non-sens |
| JP6526064B2 (ja) | 2014-06-03 | 2019-06-05 | ノバルティス アーゲー | ピリドピリミジンジオン誘導体 |
| PE20170086A1 (es) | 2014-06-03 | 2017-03-17 | Novartis Ag | Derivados de naftiridinadiona |
| WO2015186062A1 (fr) | 2014-06-03 | 2015-12-10 | Novartis Ag | Dérivés de pyrimido [4,5-b] quinoline -4,5 (3h,10h)-dione |
-
2015
- 2015-06-02 PE PE2016002514A patent/PE20170086A1/es unknown
- 2015-06-02 CU CU2016000182A patent/CU24438B1/es unknown
- 2015-06-02 US US14/728,613 patent/US10138232B2/en active Active
- 2015-06-02 TW TW104117848A patent/TWI688565B/zh not_active IP Right Cessation
- 2015-06-02 CA CA2950724A patent/CA2950724A1/fr not_active Abandoned
- 2015-06-02 AR ARP150101737A patent/AR100706A1/es unknown
- 2015-06-02 MX MX2016015856A patent/MX2016015856A/es active IP Right Grant
- 2015-06-02 BR BR112016027383A patent/BR112016027383A8/pt active Search and Examination
- 2015-06-02 CR CR20160565A patent/CR20160565A/es unknown
- 2015-06-02 WO PCT/IB2015/054174 patent/WO2015186063A1/fr active Application Filing
- 2015-06-02 TN TN2016000490A patent/TN2016000490A1/en unknown
- 2015-06-02 AU AU2015270125A patent/AU2015270125B2/en not_active Ceased
- 2015-06-02 EA EA201692270A patent/EA030374B1/ru not_active IP Right Cessation
- 2015-06-02 JP JP2016570886A patent/JP6343034B2/ja not_active Expired - Fee Related
- 2015-06-02 EP EP15731121.8A patent/EP3152209B1/fr active Active
- 2015-06-02 CN CN201580029417.3A patent/CN106459043B/zh not_active Expired - Fee Related
- 2015-06-02 SG SG11201609209YA patent/SG11201609209YA/en unknown
- 2015-06-02 KR KR1020167033550A patent/KR101905295B1/ko active IP Right Grant
- 2015-06-02 MY MYPI2016704068A patent/MY178379A/en unknown
- 2015-06-02 AP AP2016009545A patent/AP2016009545A0/en unknown
- 2015-06-02 ES ES15731121T patent/ES2731802T3/es active Active
- 2015-06-03 UY UY0001036150A patent/UY36150A/es not_active Application Discontinuation
-
2016
- 2016-11-06 IL IL248773A patent/IL248773B/en active IP Right Grant
- 2016-11-17 PH PH12016502293A patent/PH12016502293A1/en unknown
- 2016-11-30 CL CL2016003081A patent/CL2016003081A1/es unknown
- 2016-12-02 GT GT201600252A patent/GT201600252A/es unknown
- 2016-12-02 SV SV2016005331A patent/SV2016005331A/es unknown
- 2016-12-28 EC ECIEPI201696831A patent/ECSP16096831A/es unknown
-
2018
- 2018-01-18 AU AU2018200421A patent/AU2018200421A1/en not_active Withdrawn
- 2018-05-17 JP JP2018095248A patent/JP2018138609A/ja active Pending
- 2018-08-13 PH PH12018501709A patent/PH12018501709A1/en unknown
- 2018-10-10 US US16/156,447 patent/US20190248784A1/en not_active Abandoned
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