SG11201602061YA - Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom - Google Patents
Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefromInfo
- Publication number
- SG11201602061YA SG11201602061YA SG11201602061YA SG11201602061YA SG11201602061YA SG 11201602061Y A SG11201602061Y A SG 11201602061YA SG 11201602061Y A SG11201602061Y A SG 11201602061YA SG 11201602061Y A SG11201602061Y A SG 11201602061YA SG 11201602061Y A SG11201602061Y A SG 11201602061YA
- Authority
- SG
- Singapore
- Prior art keywords
- antibody
- purification method
- obtained therefrom
- novel
- antibody obtained
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/626—Diabody or triabody
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013192378 | 2013-09-17 | ||
JP2013192379 | 2013-09-17 | ||
PCT/JP2014/074452 WO2015041218A1 (fr) | 2013-09-17 | 2014-09-16 | Nouveau procédé de purification d'anticorps et anticorps obtenu au moyen de ce procédé, nouveau procédé de purification d'anticorps à l'aide d'un échangeur de cations et anticorps obtenu au moyen de ce procédé |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201602061YA true SG11201602061YA (en) | 2016-04-28 |
Family
ID=52688867
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201602061YA SG11201602061YA (en) | 2013-09-17 | 2014-09-16 | Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom |
Country Status (7)
Country | Link |
---|---|
US (1) | US10519195B2 (fr) |
EP (1) | EP3048109A4 (fr) |
JP (2) | JPWO2015041218A1 (fr) |
KR (1) | KR20160054597A (fr) |
CN (1) | CN105555795A (fr) |
SG (1) | SG11201602061YA (fr) |
WO (1) | WO2015041218A1 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016121701A1 (fr) | 2015-01-26 | 2016-08-04 | 株式会社カネカ | Matrice pour séparation par affinité destinée à la purification de protéines contenant la région variable de la chaîne kappa des immunoglobulines |
CN108064286A (zh) | 2015-01-26 | 2018-05-22 | 株式会社钟化 | 突变型免疫球蛋白κ链可变区结合性肽 |
JP6709024B2 (ja) * | 2015-07-03 | 2020-06-10 | 国立研究開発法人医薬基盤・健康・栄養研究所 | ペプチド又はタンパク質の分画方法 |
JP7084301B2 (ja) * | 2015-08-21 | 2022-06-14 | エフ.ホフマン-ラ ロシュ アーゲー | 低伝導率洗浄緩衝液を用いたアフィニティークロマトグラフィー精製方法 |
CA3000965A1 (fr) * | 2015-10-23 | 2017-04-27 | Fujifilm Corporation | Porteur de chromatographie d'affinite et methode de purification de substance biologique |
JP6737579B2 (ja) * | 2015-10-30 | 2020-08-12 | Jsr株式会社 | アフィニティークロマトグラフィー用担体、クロマトグラフィーカラム、精製方法、及び該方法で精製された標的物質 |
WO2017191747A1 (fr) * | 2016-05-06 | 2017-11-09 | 株式会社カネカ | Procédé de production d'une protéine comprenant une région variable de chaîne κ |
WO2017195638A1 (fr) | 2016-05-09 | 2017-11-16 | 株式会社カネカ | Procédé de purification d'un anticorps ou d'un fragment d'anticorps comportant une région variable de chaîne κ |
US20200360894A1 (en) | 2017-08-23 | 2020-11-19 | Jsr Corporation | Chromatography carrier, ligand-immobilizing carrier, chromatography column, target substance purification method, and chromatography carrier production method |
CN117920163A (zh) | 2018-11-06 | 2024-04-26 | Jsr株式会社 | 有机硫化合物的制造方法 |
JP7154414B2 (ja) * | 2019-07-02 | 2022-10-17 | 日本メジフィジックス株式会社 | 226Ra含有溶液の精製方法、226Raターゲットの製造方法および225Acの製造方法 |
WO2022202467A1 (fr) | 2021-03-25 | 2022-09-29 | Jsr株式会社 | Procédé de production de support pour une utilisation chromatographique, procédé de production de colonne de chromatographie, et support pour une utilisation chromatographique |
WO2022202466A1 (fr) | 2021-03-25 | 2022-09-29 | Jsr株式会社 | Procédé de production d'un vecteur chromatographique, procédé de production d'une colonne de chromatographie et vecteur chromatographique |
WO2023058409A1 (fr) | 2021-10-05 | 2023-04-13 | Jsr株式会社 | Procédé de remplissage de colonne avec un support de chromatographie, procédé de stockage de suspension épaisse, et suspension épaisse |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3932557A (en) | 1972-12-19 | 1976-01-13 | Gulf Research & Development Company | Reactive hydrophilic epoxy containing polymer |
US4145366A (en) * | 1974-11-18 | 1979-03-20 | Teijin Limited | Process for isomerizing one of the geometric isomers of an α,β-unsaturated aldehyde to its corresponding other geometric isomer |
US4210723A (en) | 1976-07-23 | 1980-07-01 | The Dow Chemical Company | Method of coupling a protein to an epoxylated latex |
US4772653A (en) | 1985-11-08 | 1988-09-20 | Amoco Corporation | Stain resistant cookware from blends comprising an interpolymer of an unsaturated dicarboxylic acid compound |
US5260373A (en) | 1987-03-13 | 1993-11-09 | Repligen Corporation | Immobilized immunoglobulin-binding proteins |
SE467308B (sv) | 1990-10-22 | 1992-06-29 | Berol Nobel Ab | Fast yta belagd med ett hydrofilt ytterskikt med kovalent bundna biopolymerer, saett att framstaella en saadan yta och ett konjugat daerfoer |
JPH05202098A (ja) | 1992-01-29 | 1993-08-10 | Snow Brand Milk Prod Co Ltd | 乳質原料から生理活性物質の製造法 |
JPH06228200A (ja) | 1993-01-29 | 1994-08-16 | Snow Brand Milk Prod Co Ltd | 補体C3cの製造法 |
SE9503925D0 (sv) | 1995-11-07 | 1995-11-07 | Pharmacia Biotech Ab | Separationsmedium för IgG |
US5874165A (en) | 1996-06-03 | 1999-02-23 | Gore Enterprise Holdings, Inc. | Materials and method for the immobilization of bioactive species onto polymeric subtrates |
ATE370961T1 (de) * | 1998-05-06 | 2007-09-15 | Genentech Inc | Reinigung von antikörpern durch ionenaustauschchromatographie |
EP1105731B1 (fr) | 1998-08-12 | 2006-10-18 | Zycos Inc. | Etablissement de profil et catalogage de marqueurs de proteines exprimees |
US20040224338A1 (en) | 1998-08-12 | 2004-11-11 | Zycos Inc., A Delaware Corporation | Profiling and cataloging expressed protein tags |
SE0200943D0 (sv) | 2002-03-25 | 2002-03-25 | Amersham Biosciences Ab | Mutant protein |
US7709209B2 (en) | 2002-03-25 | 2010-05-04 | Ge Healthcare Bio-Sciences Ab | Protein ligands |
ITMI20020729A1 (it) | 2002-04-08 | 2003-10-08 | Resindion S R L | Supporti per l'immobilizzazione covalente di enzimi |
ES2214136B1 (es) | 2003-02-21 | 2007-05-16 | Consejo Sup. De Invest. Cientificas. | Nuevo metodo de inmovilizacion de enzimas y otras bio-macromoleculas sobre soportes activados con grupos epoxido conteniendo grupos ionizados en el brazo espaciador que une cada grupo epoxido a la superficie del soporte. |
GB0304576D0 (en) * | 2003-02-28 | 2003-04-02 | Lonza Biologics Plc | Protein a chromatography |
SE0400501D0 (sv) | 2004-02-27 | 2004-02-27 | Amersham Biosciences Ab | Antibody purification |
CA2552639C (fr) | 2004-02-27 | 2012-05-01 | Ge Healthcare Bio-Sciences Ab | Procede de purification d'anticorps |
SE0400886D0 (sv) * | 2004-04-02 | 2004-04-02 | Amersham Biosciences Ab | Process of purification |
KR101248642B1 (ko) | 2004-06-09 | 2013-03-28 | 페써겐 리무벌 앤드 다이어그너스틱 테크널라지스 인코포레이티드 | 샘플로부터 목적 약물을 제거하기 위한 다공성 기질 내함침된 입자들 |
RU2389552C2 (ru) | 2004-10-21 | 2010-05-20 | Джи-И Хелткер Байо-Сайенсиз АБ | Способ очистки антител |
US9266041B2 (en) | 2004-10-21 | 2016-02-23 | Ge Healthcare Bio-Sciences Ab | Chromatography ligand |
CA2604877A1 (fr) | 2005-04-11 | 2006-10-19 | J.P. Sercel Associates Inc. | Purification des proteines |
TWI391399B (zh) * | 2005-05-25 | 2013-04-01 | Hoffmann La Roche | 測定溶離多肽之鹽濃度之方法 |
WO2007081851A2 (fr) | 2006-01-06 | 2007-07-19 | Millipore Corporation | Matrices de chromatographie d'affinite et procedes de fabrication et d'utilisation correspondants |
WO2009017491A1 (fr) | 2006-06-14 | 2009-02-05 | Smithkline Beecham Corporation | Procédés de purification d'anticorps à l'aide de céramique d'hydroxyapatite |
JP5448825B2 (ja) | 2006-10-19 | 2014-03-19 | ヤンセン バイオテツク,インコーポレーテツド | 非凝集抗体Fcドメインの製造方法 |
US20080167450A1 (en) | 2007-01-05 | 2008-07-10 | Hai Pan | Methods of purifying proteins |
US7999085B2 (en) | 2007-01-09 | 2011-08-16 | Bio-Rad Laboratories, Inc. | Enhanced capacity and purification of protein by mixed mode chromatography in the presence of aqueous-soluble nonionic organic polymers |
US7691980B2 (en) | 2007-01-09 | 2010-04-06 | Bio-Rad Laboratories, Inc. | Enhanced capacity and purification of antibodies by mixed mode chromatography in the presence of aqueous-soluble nonionic organic polymers |
US9433922B2 (en) | 2007-08-14 | 2016-09-06 | Emd Millipore Corporation | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
WO2009058769A1 (fr) | 2007-10-30 | 2009-05-07 | Schering Corporation | Purification d'anticorps contenant des variants hydrophobes |
CA2720615C (fr) | 2008-04-08 | 2016-06-07 | Bio-Rad Laboratories, Inc. | Purification d'anticorps par chromatographie |
EP2281000A2 (fr) * | 2008-05-15 | 2011-02-09 | Novo Nordisk A/S | Procédé de purification d'anticorps |
EP2321338A1 (fr) | 2008-08-14 | 2011-05-18 | Merck Sharp & Dohme Corp. | Procédés de purification d'anticorps à l'aide d'une chromatographie d'affinité sur protéine a |
CA2932207A1 (fr) | 2008-10-20 | 2010-12-09 | Abbvie Inc. | Isolation et purification d'anticorps au moyen de chromatographie d'affinite de proteine a |
JP2010133734A (ja) | 2008-12-02 | 2010-06-17 | Tosoh Corp | アフィニティークロマトグラフィー用カルボキシル化担体、及びそれを用いたアフィニティークロマトグラフィー用分離剤 |
JP2010133733A (ja) | 2008-12-02 | 2010-06-17 | Tosoh Corp | カチオン交換体、その製造方法及びその用途 |
WO2010071208A1 (fr) | 2008-12-19 | 2010-06-24 | 武田薬品工業株式会社 | Méthode de purification d'anticorps |
US9676845B2 (en) * | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
CN107188960A (zh) * | 2009-08-07 | 2017-09-22 | Emd密理博公司 | 从样品的一或多种杂质中纯化靶蛋白的方法 |
US9527010B2 (en) * | 2009-09-25 | 2016-12-27 | Ge Healthcare Bio-Sciences Corp. | Separation system and method |
ES2813398T3 (es) | 2009-10-20 | 2021-03-23 | Abbvie Inc | Aislamiento y purificación de anticuerpos anti-IL-13 usando cromatografía de afinidad a Proteína A |
US8277649B2 (en) | 2009-12-14 | 2012-10-02 | General Electric Company | Membranes and associated methods for purification of antibodies |
SG184184A1 (en) | 2010-03-24 | 2012-10-30 | Kaneka Corp | Protein capable of binding specifically to immunoglobulin, and immunoglobulin-binding affinity ligand |
EP2649016B1 (fr) * | 2010-12-06 | 2020-06-10 | Pall Corporation | Procédés de traitement continu pour produits biologiques |
JP6335785B2 (ja) | 2012-09-03 | 2018-05-30 | 株式会社カネカ | ミックスモード抗体アフィニティー分離マトリックスとそれを用いた精製方法および標的分子 |
CN116003579A (zh) * | 2013-05-06 | 2023-04-25 | 赛诺菲 | 用于纯化抗体的连续多步骤方法 |
-
2014
- 2014-09-16 WO PCT/JP2014/074452 patent/WO2015041218A1/fr active Application Filing
- 2014-09-16 CN CN201480051360.2A patent/CN105555795A/zh active Pending
- 2014-09-16 SG SG11201602061YA patent/SG11201602061YA/en unknown
- 2014-09-16 EP EP14846521.4A patent/EP3048109A4/fr not_active Withdrawn
- 2014-09-16 US US15/022,890 patent/US10519195B2/en active Active
- 2014-09-16 JP JP2015537927A patent/JPWO2015041218A1/ja active Pending
- 2014-09-16 KR KR1020167009648A patent/KR20160054597A/ko not_active Application Discontinuation
-
2018
- 2018-11-06 JP JP2018209021A patent/JP2019034963A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CN105555795A (zh) | 2016-05-04 |
KR20160054597A (ko) | 2016-05-16 |
US10519195B2 (en) | 2019-12-31 |
JPWO2015041218A1 (ja) | 2017-03-02 |
JP2019034963A (ja) | 2019-03-07 |
US20160237113A1 (en) | 2016-08-18 |
EP3048109A1 (fr) | 2016-07-27 |
WO2015041218A1 (fr) | 2015-03-26 |
EP3048109A4 (fr) | 2017-04-19 |
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