SG11201510216RA - Stabilized soluble pre-fusion rsv f polypeptides - Google Patents
Stabilized soluble pre-fusion rsv f polypeptidesInfo
- Publication number
- SG11201510216RA SG11201510216RA SG11201510216RA SG11201510216RA SG11201510216RA SG 11201510216R A SG11201510216R A SG 11201510216RA SG 11201510216R A SG11201510216R A SG 11201510216RA SG 11201510216R A SG11201510216R A SG 11201510216RA SG 11201510216R A SG11201510216R A SG 11201510216RA
- Authority
- SG
- Singapore
- Prior art keywords
- polypeptides
- fusion rsv
- soluble pre
- stabilized soluble
- stabilized
- Prior art date
Links
- 230000004927 fusion Effects 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/115—Paramyxoviridae, e.g. parainfluenza virus
- C07K14/135—Respiratory syncytial virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2999/00—Further aspects of viruses or vectors not covered by groups C12N2710/00 - C12N2796/00 or C12N2800/00
- C12N2999/002—Adverse teaching
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cosmetics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13172256 | 2013-06-17 | ||
PCT/EP2014/062655 WO2014202570A1 (fr) | 2013-06-17 | 2014-06-17 | Polypeptides f solubles et stabilisés du vrs en conformation pré-fusion |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201510216RA true SG11201510216RA (en) | 2016-01-28 |
Family
ID=48625910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201510216RA SG11201510216RA (en) | 2013-06-17 | 2014-06-17 | Stabilized soluble pre-fusion rsv f polypeptides |
Country Status (20)
Country | Link |
---|---|
US (1) | US10294279B2 (fr) |
EP (1) | EP3010931B1 (fr) |
JP (1) | JP6679475B2 (fr) |
KR (1) | KR102313153B1 (fr) |
CN (1) | CN105408348B (fr) |
AP (1) | AP2015008893A0 (fr) |
AU (1) | AU2014283334B2 (fr) |
BR (1) | BR112015031509B1 (fr) |
CA (1) | CA2914792C (fr) |
CL (1) | CL2015003655A1 (fr) |
EA (1) | EA034653B1 (fr) |
HK (1) | HK1223949A1 (fr) |
IL (1) | IL243053B (fr) |
MX (1) | MX362792B (fr) |
MY (1) | MY171210A (fr) |
PE (1) | PE20160045A1 (fr) |
PH (1) | PH12015502735A1 (fr) |
SG (1) | SG11201510216RA (fr) |
WO (1) | WO2014202570A1 (fr) |
ZA (1) | ZA201509140B (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
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AP2015008815A0 (en) | 2013-04-25 | 2015-10-31 | Crucell Holland Bv | Stabilized soluble prefusion rsv f polypeptides |
PE20160045A1 (es) | 2013-06-17 | 2016-02-18 | Crucell Holland Bv | Polipeptidos f de prefusion del virus sincicial respiratorio (rsv) solubles y estabilizados |
CN116059336A (zh) | 2015-07-07 | 2023-05-05 | 扬森疫苗与预防公司 | 针对rsv的疫苗 |
WO2017005848A1 (fr) | 2015-07-07 | 2017-01-12 | Janssen Vaccines & Prevention B.V. | Polypeptides f du vrs de pré-fusion solubles stabilisés |
RU2723039C2 (ru) | 2015-12-23 | 2020-06-08 | Пфайзер Инк. | Мутанты белка f rsv |
KR102401247B1 (ko) | 2016-04-05 | 2022-05-25 | 얀센 백신스 앤드 프리벤션 비.브이. | Rsv에 대한 백신 |
SI3439672T1 (sl) | 2016-04-05 | 2021-02-26 | Janssen Vaccines & Prevention B.V. | Stabiliziran topen pre-fuzijski F protein RSV za uporabo v profilaksi okužbe z RSV |
WO2017207477A1 (fr) | 2016-05-30 | 2017-12-07 | Janssen Vaccines & Prevention B.V. | Protéines f du vrs de pré-fusion solubles stabilisées |
MX2018014699A (es) | 2016-05-30 | 2019-02-28 | Janssen Vaccines & Prevention Bv | Proteinas f de prefusion del vrs estabilizadas. |
EP3595713A4 (fr) | 2017-03-15 | 2021-01-13 | ModernaTX, Inc. | Vaccin contre le virus respiratoire syncytial |
WO2018170347A1 (fr) | 2017-03-17 | 2018-09-20 | Modernatx, Inc. | Vaccins à base d'arn contre des maladies zoonotiques |
US11192926B2 (en) | 2017-04-04 | 2021-12-07 | University Of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus F proteins and their use |
CA3061678A1 (fr) | 2017-05-15 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Composition contenant un virus stable |
CA3062549A1 (fr) | 2017-05-15 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Composition contenant un virus stable |
WO2018210871A1 (fr) * | 2017-05-17 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Procédés et compositions pour induire une immunité protectrice contre l'infection par le vrs |
AU2018267971A1 (en) | 2017-05-17 | 2019-11-07 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against RSV infection |
EA202090738A1 (ru) * | 2017-09-15 | 2020-06-10 | Янссен Вэксинс Энд Превеншн Б.В. | Способ безопасного индуцирования иммунитета против rsv |
US11911453B2 (en) | 2018-01-29 | 2024-02-27 | Modernatx, Inc. | RSV RNA vaccines |
WO2020099383A1 (fr) | 2018-11-13 | 2020-05-22 | Janssen Vaccines & Prevention B.V. | Protéines f du vrs sous forme pré-fusion stabilisées |
EP3969044A1 (fr) | 2019-05-15 | 2022-03-23 | Janssen Vaccines & Prevention B.V. | Co-administration d'un vaccin contre la grippe saisonnière et vaccin contre le virus respiratoire syncytial à base d'adénovirus |
MX2021013947A (es) | 2019-05-15 | 2021-12-14 | Janssen Vaccines & Prevention Bv | Tratamiento profilactico de la infeccion por virus sincitial respiratorio con una vacuna basada en adenovirus. |
CN114502572A (zh) | 2019-09-04 | 2022-05-13 | 华盛顿大学 | 展示副粘病毒和/或肺炎病毒f蛋白的自组装蛋白纳米结构及其用途 |
AU2021250630A1 (en) | 2020-04-02 | 2022-10-20 | Janssen Vaccines & Prevention B.V. | Stabilized vaccine compositions |
JP2022060169A (ja) | 2020-10-02 | 2022-04-14 | ファイザー・インク | Rsv fタンパク質生産のための細胞培養工程 |
CN115161344A (zh) * | 2022-04-26 | 2022-10-11 | 北京智飞绿竹生物制药有限公司 | 一种针对呼吸道合胞病毒感染的疫苗的制备方法 |
WO2024067725A1 (fr) * | 2022-09-29 | 2024-04-04 | 北京百邑无忧科技发展有限公司 | Protéine de fusion recombinante du virus respiratoire syncytial à conformation de préfusion, son procédé de préparation et son utilisation |
WO2024067723A1 (fr) * | 2022-09-29 | 2024-04-04 | 北京百邑无忧科技发展有限公司 | Protéine de fusion recombinante du virus respiratoire syncytial ayant une conformation de pré-fusion, son procédé de préparation et son utilisation |
WO2024069420A2 (fr) | 2022-09-29 | 2024-04-04 | Pfizer Inc. | Compositions immunogènes comprenant un trimère de protéine f rsv |
WO2024089634A1 (fr) | 2022-10-27 | 2024-05-02 | Pfizer Inc. | Compositions immunogènes contre la grippe et le vrs |
WO2024089633A1 (fr) | 2022-10-27 | 2024-05-02 | Pfizer Inc. | Molécules d'arn codant pour le vrs-f et vaccins les contenant |
CN117586358A (zh) * | 2024-01-19 | 2024-02-23 | 北京安百胜生物科技有限公司 | 一种具有免疫原性的呼吸道合胞病毒(rsv)多肽 |
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RU2761631C2 (ru) * | 2013-03-13 | 2021-12-13 | Дзе Юнайтед Стэйтс Оф Америка, Эс Репрезентед Бай Дзе Секретэри, Департмент Оф Хелт Энд Хьюман Сервисиз | Белки rsv в предшествующей слиянию конформации и их применение |
US9738689B2 (en) | 2013-03-13 | 2017-08-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Prefusion RSV F proteins and their use |
AU2014255865B2 (en) | 2013-04-15 | 2019-07-18 | Janssen Vaccines & Prevention B.V. | Human antibodies binding to RSV G proteins |
EP2986637A1 (fr) | 2013-04-15 | 2016-02-24 | Crucell Holland B.V. | Anticorps humains se liant à la protéine g du virus respiratoire syncytial (rsv) |
AP2015008815A0 (en) | 2013-04-25 | 2015-10-31 | Crucell Holland Bv | Stabilized soluble prefusion rsv f polypeptides |
PE20160045A1 (es) | 2013-06-17 | 2016-02-18 | Crucell Holland Bv | Polipeptidos f de prefusion del virus sincicial respiratorio (rsv) solubles y estabilizados |
-
2014
- 2014-06-17 PE PE2015002617A patent/PE20160045A1/es unknown
- 2014-06-17 MY MYPI2015704549A patent/MY171210A/en unknown
- 2014-06-17 EA EA201690031A patent/EA034653B1/ru not_active IP Right Cessation
- 2014-06-17 KR KR1020167000649A patent/KR102313153B1/ko active IP Right Grant
- 2014-06-17 JP JP2016520435A patent/JP6679475B2/ja active Active
- 2014-06-17 AU AU2014283334A patent/AU2014283334B2/en active Active
- 2014-06-17 EP EP14731940.4A patent/EP3010931B1/fr active Active
- 2014-06-17 US US14/899,531 patent/US10294279B2/en active Active
- 2014-06-17 SG SG11201510216RA patent/SG11201510216RA/en unknown
- 2014-06-17 AP AP2015008893A patent/AP2015008893A0/xx unknown
- 2014-06-17 BR BR112015031509-7A patent/BR112015031509B1/pt active IP Right Grant
- 2014-06-17 MX MX2015017771A patent/MX362792B/es active IP Right Grant
- 2014-06-17 WO PCT/EP2014/062655 patent/WO2014202570A1/fr active Application Filing
- 2014-06-17 CA CA2914792A patent/CA2914792C/fr active Active
- 2014-06-17 CN CN201480034307.1A patent/CN105408348B/zh active Active
-
2015
- 2015-12-07 PH PH12015502735A patent/PH12015502735A1/en unknown
- 2015-12-13 IL IL243053A patent/IL243053B/en active IP Right Grant
- 2015-12-15 ZA ZA2015/09140A patent/ZA201509140B/en unknown
- 2015-12-17 CL CL2015003655A patent/CL2015003655A1/es unknown
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2016
- 2016-10-24 HK HK16112203.0A patent/HK1223949A1/zh unknown
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Publication number | Publication date |
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JP2016522230A (ja) | 2016-07-28 |
NZ714594A (en) | 2021-07-30 |
EA201690031A1 (ru) | 2016-07-29 |
CN105408348B (zh) | 2021-07-06 |
WO2014202570A1 (fr) | 2014-12-24 |
JP6679475B2 (ja) | 2020-04-15 |
MX362792B (es) | 2019-02-13 |
KR102313153B1 (ko) | 2021-10-15 |
AU2014283334A1 (en) | 2015-12-17 |
HK1223949A1 (zh) | 2017-08-11 |
BR112015031509A2 (pt) | 2017-08-29 |
AP2015008893A0 (en) | 2015-12-31 |
EP3010931B1 (fr) | 2018-06-13 |
CL2015003655A1 (es) | 2016-06-03 |
MX2015017771A (es) | 2016-10-04 |
US20160176932A1 (en) | 2016-06-23 |
MY171210A (en) | 2019-10-02 |
BR112015031509B1 (pt) | 2023-05-09 |
EA034653B1 (ru) | 2020-03-03 |
US10294279B2 (en) | 2019-05-21 |
AU2014283334B2 (en) | 2018-10-18 |
PH12015502735B1 (en) | 2016-03-07 |
CN105408348A (zh) | 2016-03-16 |
IL243053B (en) | 2020-06-30 |
KR20160021196A (ko) | 2016-02-24 |
ZA201509140B (en) | 2022-03-30 |
CA2914792A1 (fr) | 2014-12-24 |
PE20160045A1 (es) | 2016-02-18 |
EP3010931A1 (fr) | 2016-04-27 |
PH12015502735A1 (en) | 2016-03-07 |
CA2914792C (fr) | 2024-02-27 |
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