BR112015031509A2 - Polipeptídeo, molécula de ácido nucleico, vetor, e, composição - Google Patents
Polipeptídeo, molécula de ácido nucleico, vetor, e, composiçãoInfo
- Publication number
- BR112015031509A2 BR112015031509A2 BR112015031509A BR112015031509A BR112015031509A2 BR 112015031509 A2 BR112015031509 A2 BR 112015031509A2 BR 112015031509 A BR112015031509 A BR 112015031509A BR 112015031509 A BR112015031509 A BR 112015031509A BR 112015031509 A2 BR112015031509 A2 BR 112015031509A2
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- vector
- composition
- nucleic acid
- acid molecule
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 241000725643 Respiratory syncytial virus Species 0.000 abstract 2
- 206010061603 Respiratory syncytial virus infection Diseases 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/115—Paramyxoviridae, e.g. parainfluenza virus
- C07K14/135—Respiratory syncytial virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2999/00—Further aspects of viruses or vectors not covered by groups C12N2710/00 - C12N2796/00 or C12N2800/00
- C12N2999/002—Adverse teaching
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cosmetics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13172256.3 | 2013-06-17 | ||
EP13172256 | 2013-06-17 | ||
PCT/EP2014/062655 WO2014202570A1 (en) | 2013-06-17 | 2014-06-17 | Stabilized soluble pre-fusion rsv f polypeptides |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112015031509A2 true BR112015031509A2 (pt) | 2017-08-29 |
BR112015031509B1 BR112015031509B1 (pt) | 2023-05-09 |
Family
ID=48625910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015031509-7A BR112015031509B1 (pt) | 2013-06-17 | 2014-06-17 | Polipeptídeo de fusão (f) do vírus sincicial respiratório (rsv) pré- fusão recombinante e composição que o compreende |
Country Status (20)
Country | Link |
---|---|
US (1) | US10294279B2 (pt) |
EP (1) | EP3010931B1 (pt) |
JP (1) | JP6679475B2 (pt) |
KR (1) | KR102313153B1 (pt) |
CN (1) | CN105408348B (pt) |
AP (1) | AP2015008893A0 (pt) |
AU (1) | AU2014283334B2 (pt) |
BR (1) | BR112015031509B1 (pt) |
CA (1) | CA2914792C (pt) |
CL (1) | CL2015003655A1 (pt) |
EA (1) | EA034653B1 (pt) |
HK (1) | HK1223949A1 (pt) |
IL (1) | IL243053B (pt) |
MX (1) | MX362792B (pt) |
MY (1) | MY171210A (pt) |
PE (1) | PE20160045A1 (pt) |
PH (1) | PH12015502735A1 (pt) |
SG (1) | SG11201510216RA (pt) |
WO (1) | WO2014202570A1 (pt) |
ZA (1) | ZA201509140B (pt) |
Families Citing this family (31)
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AP2015008815A0 (en) | 2013-04-25 | 2015-10-31 | Crucell Holland Bv | Stabilized soluble prefusion rsv f polypeptides |
PE20160045A1 (es) | 2013-06-17 | 2016-02-18 | Crucell Holland Bv | Polipeptidos f de prefusion del virus sincicial respiratorio (rsv) solubles y estabilizados |
CN116059336A (zh) | 2015-07-07 | 2023-05-05 | 扬森疫苗与预防公司 | 针对rsv的疫苗 |
WO2017005848A1 (en) | 2015-07-07 | 2017-01-12 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion rsv f polypeptides |
RU2723039C2 (ru) | 2015-12-23 | 2020-06-08 | Пфайзер Инк. | Мутанты белка f rsv |
KR102401247B1 (ko) | 2016-04-05 | 2022-05-25 | 얀센 백신스 앤드 프리벤션 비.브이. | Rsv에 대한 백신 |
SI3439672T1 (sl) | 2016-04-05 | 2021-02-26 | Janssen Vaccines & Prevention B.V. | Stabiliziran topen pre-fuzijski F protein RSV za uporabo v profilaksi okužbe z RSV |
WO2017207477A1 (en) | 2016-05-30 | 2017-12-07 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv f proteins |
MX2018014699A (es) | 2016-05-30 | 2019-02-28 | Janssen Vaccines & Prevention Bv | Proteinas f de prefusion del vrs estabilizadas. |
EP3595713A4 (en) | 2017-03-15 | 2021-01-13 | ModernaTX, Inc. | RESPIRATORY SYNCYTIAL VIRUS VACCINE |
WO2018170347A1 (en) | 2017-03-17 | 2018-09-20 | Modernatx, Inc. | Zoonotic disease rna vaccines |
US11192926B2 (en) | 2017-04-04 | 2021-12-07 | University Of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus F proteins and their use |
CA3061678A1 (en) | 2017-05-15 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
CA3062549A1 (en) | 2017-05-15 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
WO2018210871A1 (en) * | 2017-05-17 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against rsv infection |
AU2018267971A1 (en) | 2017-05-17 | 2019-11-07 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against RSV infection |
EA202090738A1 (ru) * | 2017-09-15 | 2020-06-10 | Янссен Вэксинс Энд Превеншн Б.В. | Способ безопасного индуцирования иммунитета против rsv |
US11911453B2 (en) | 2018-01-29 | 2024-02-27 | Modernatx, Inc. | RSV RNA vaccines |
WO2020099383A1 (en) | 2018-11-13 | 2020-05-22 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv f proteins |
EP3969044A1 (en) | 2019-05-15 | 2022-03-23 | Janssen Vaccines & Prevention B.V. | Co-administration of seasonal influenza vaccine and an adenovirus based respiratory syncytial virus vaccine |
MX2021013947A (es) | 2019-05-15 | 2021-12-14 | Janssen Vaccines & Prevention Bv | Tratamiento profilactico de la infeccion por virus sincitial respiratorio con una vacuna basada en adenovirus. |
CN114502572A (zh) | 2019-09-04 | 2022-05-13 | 华盛顿大学 | 展示副粘病毒和/或肺炎病毒f蛋白的自组装蛋白纳米结构及其用途 |
AU2021250630A1 (en) | 2020-04-02 | 2022-10-20 | Janssen Vaccines & Prevention B.V. | Stabilized vaccine compositions |
JP2022060169A (ja) | 2020-10-02 | 2022-04-14 | ファイザー・インク | Rsv fタンパク質生産のための細胞培養工程 |
CN115161344A (zh) * | 2022-04-26 | 2022-10-11 | 北京智飞绿竹生物制药有限公司 | 一种针对呼吸道合胞病毒感染的疫苗的制备方法 |
WO2024067725A1 (zh) * | 2022-09-29 | 2024-04-04 | 北京百邑无忧科技发展有限公司 | 一种融合前构象的呼吸道合胞病毒重组融合蛋白、其制备方法及用途 |
WO2024067723A1 (zh) * | 2022-09-29 | 2024-04-04 | 北京百邑无忧科技发展有限公司 | 一种融合前构象的呼吸道合胞病毒重组融合蛋白、其制备方法及用途 |
WO2024069420A2 (en) | 2022-09-29 | 2024-04-04 | Pfizer Inc. | Immunogenic compositions comprising an rsv f protein trimer |
WO2024089634A1 (en) | 2022-10-27 | 2024-05-02 | Pfizer Inc. | Immunogenic compositions against influenza and rsv |
WO2024089633A1 (en) | 2022-10-27 | 2024-05-02 | Pfizer Inc. | Rna molecules encoding rsv-f and vaccines containing them |
CN117586358A (zh) * | 2024-01-19 | 2024-02-23 | 北京安百胜生物科技有限公司 | 一种具有免疫原性的呼吸道合胞病毒(rsv)多肽 |
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JP2013247240A (ja) | 2012-05-25 | 2013-12-09 | Gigaphoton Inc | レーザ装置 |
RU2761631C2 (ru) * | 2013-03-13 | 2021-12-13 | Дзе Юнайтед Стэйтс Оф Америка, Эс Репрезентед Бай Дзе Секретэри, Департмент Оф Хелт Энд Хьюман Сервисиз | Белки rsv в предшествующей слиянию конформации и их применение |
US9738689B2 (en) | 2013-03-13 | 2017-08-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Prefusion RSV F proteins and their use |
AU2014255865B2 (en) | 2013-04-15 | 2019-07-18 | Janssen Vaccines & Prevention B.V. | Human antibodies binding to RSV G proteins |
EP2986637A1 (en) | 2013-04-15 | 2016-02-24 | Crucell Holland B.V. | Human antibodies binding to rsv g protein |
AP2015008815A0 (en) | 2013-04-25 | 2015-10-31 | Crucell Holland Bv | Stabilized soluble prefusion rsv f polypeptides |
PE20160045A1 (es) | 2013-06-17 | 2016-02-18 | Crucell Holland Bv | Polipeptidos f de prefusion del virus sincicial respiratorio (rsv) solubles y estabilizados |
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JP2016522230A (ja) | 2016-07-28 |
NZ714594A (en) | 2021-07-30 |
EA201690031A1 (ru) | 2016-07-29 |
CN105408348B (zh) | 2021-07-06 |
WO2014202570A1 (en) | 2014-12-24 |
JP6679475B2 (ja) | 2020-04-15 |
MX362792B (es) | 2019-02-13 |
KR102313153B1 (ko) | 2021-10-15 |
AU2014283334A1 (en) | 2015-12-17 |
HK1223949A1 (zh) | 2017-08-11 |
AP2015008893A0 (en) | 2015-12-31 |
EP3010931B1 (en) | 2018-06-13 |
CL2015003655A1 (es) | 2016-06-03 |
MX2015017771A (es) | 2016-10-04 |
US20160176932A1 (en) | 2016-06-23 |
MY171210A (en) | 2019-10-02 |
BR112015031509B1 (pt) | 2023-05-09 |
EA034653B1 (ru) | 2020-03-03 |
US10294279B2 (en) | 2019-05-21 |
AU2014283334B2 (en) | 2018-10-18 |
PH12015502735B1 (en) | 2016-03-07 |
CN105408348A (zh) | 2016-03-16 |
IL243053B (en) | 2020-06-30 |
KR20160021196A (ko) | 2016-02-24 |
ZA201509140B (en) | 2022-03-30 |
CA2914792A1 (en) | 2014-12-24 |
PE20160045A1 (es) | 2016-02-18 |
EP3010931A1 (en) | 2016-04-27 |
SG11201510216RA (en) | 2016-01-28 |
PH12015502735A1 (en) | 2016-03-07 |
CA2914792C (en) | 2024-02-27 |
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