SG11201510216RA - Stabilized soluble pre-fusion rsv f polypeptides - Google Patents

Stabilized soluble pre-fusion rsv f polypeptides

Info

Publication number
SG11201510216RA
SG11201510216RA SG11201510216RA SG11201510216RA SG11201510216RA SG 11201510216R A SG11201510216R A SG 11201510216RA SG 11201510216R A SG11201510216R A SG 11201510216RA SG 11201510216R A SG11201510216R A SG 11201510216RA SG 11201510216R A SG11201510216R A SG 11201510216RA
Authority
SG
Singapore
Prior art keywords
polypeptides
fusion rsv
soluble pre
stabilized soluble
stabilized
Prior art date
Application number
SG11201510216RA
Inventor
Johannes Petrus Maria Langedijk
Anders Krarup
Original Assignee
Crucell Holland Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crucell Holland Bv filed Critical Crucell Holland Bv
Publication of SG11201510216RA publication Critical patent/SG11201510216RA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/115Paramyxoviridae, e.g. parainfluenza virus
    • C07K14/135Respiratory syncytial virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2999/00Further aspects of viruses or vectors not covered by groups C12N2710/00 - C12N2796/00 or C12N2800/00
    • C12N2999/002Adverse teaching

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
SG11201510216RA 2013-06-17 2014-06-17 Stabilized soluble pre-fusion rsv f polypeptides SG11201510216RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13172256 2013-06-17
PCT/EP2014/062655 WO2014202570A1 (en) 2013-06-17 2014-06-17 Stabilized soluble pre-fusion rsv f polypeptides

Publications (1)

Publication Number Publication Date
SG11201510216RA true SG11201510216RA (en) 2016-01-28

Family

ID=48625910

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201510216RA SG11201510216RA (en) 2013-06-17 2014-06-17 Stabilized soluble pre-fusion rsv f polypeptides

Country Status (20)

Country Link
US (1) US10294279B2 (en)
EP (1) EP3010931B1 (en)
JP (1) JP6679475B2 (en)
KR (1) KR102313153B1 (en)
CN (1) CN105408348B (en)
AP (1) AP2015008893A0 (en)
AU (1) AU2014283334B2 (en)
BR (1) BR112015031509B1 (en)
CA (1) CA2914792C (en)
CL (1) CL2015003655A1 (en)
EA (1) EA034653B1 (en)
HK (1) HK1223949A1 (en)
IL (1) IL243053B (en)
MX (1) MX362792B (en)
MY (1) MY171210A (en)
PE (1) PE20160045A1 (en)
PH (1) PH12015502735B1 (en)
SG (1) SG11201510216RA (en)
WO (1) WO2014202570A1 (en)
ZA (1) ZA201509140B (en)

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PE20160045A1 (en) 2013-06-17 2016-02-18 Crucell Holland Bv SOLUBLE AND STABILIZED RESPIRATORY SYNCITIAL VIRUS (RSV) PREFUSION POLYPEPTIDES F
WO2017005844A1 (en) 2015-07-07 2017-01-12 Janssen Vaccines & Prevention B.V. Vaccine against rsv
JP6840718B2 (en) 2015-07-07 2021-03-10 ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. Stabilized pre-soluble fusion RSV F polypeptide
PE20181354A1 (en) 2015-12-23 2018-08-22 Pfizer RSV PROTEIN F MUTANTS
AU2017248021B2 (en) * 2016-04-05 2021-08-12 Janssen Vaccines & Prevention B.V. Stabilized soluble pre-fusion RSV F proteins
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WO2017207477A1 (en) 2016-05-30 2017-12-07 Janssen Vaccines & Prevention B.V. Stabilized pre-fusion rsv f proteins
WO2017207480A1 (en) * 2016-05-30 2017-12-07 Janssen Vaccines & Prevention B.V. Stabilized pre-fusion rsv f proteins
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US20220306697A1 (en) 2019-09-04 2022-09-29 University Of Washington Self-Assembling Protein Nanostructures Displaying Paramyxovirus and/or Pneumovirus F Proteins and Their Use
JP2023519740A (en) 2020-04-02 2023-05-12 ヤンセン ファッシンズ アンド プリベンション ベーフェー Stabilized vaccine composition
JP2022060169A (en) 2020-10-02 2022-04-14 ファイザー・インク Cell culture process for rsv f protein production
CN115161344A (en) * 2022-04-26 2022-10-11 北京智飞绿竹生物制药有限公司 Preparation method of vaccine for respiratory syncytial virus infection
WO2024067725A1 (en) * 2022-09-29 2024-04-04 北京百邑无忧科技发展有限公司 Respiratory syncytial virus recombinant fusion protein with prefusion conformation, and preparation method therefor and use thereof
WO2024067723A1 (en) * 2022-09-29 2024-04-04 北京百邑无忧科技发展有限公司 Respiratory syncytial virus recombinant fusion protein having pre-fusion conformation, and preparation method therefor and use thereof
WO2024069420A2 (en) 2022-09-29 2024-04-04 Pfizer Inc. Immunogenic compositions comprising an rsv f protein trimer
WO2024089634A1 (en) 2022-10-27 2024-05-02 Pfizer Inc. Immunogenic compositions against influenza and rsv
WO2024089633A1 (en) 2022-10-27 2024-05-02 Pfizer Inc. Rna molecules encoding rsv-f and vaccines containing them
WO2024127181A1 (en) 2022-12-11 2024-06-20 Pfizer Inc. Immunogenic compositions against influenza and rsv
CN117736278A (en) * 2023-12-25 2024-03-22 英诺特(唐山)生物技术有限公司 Kit and detection method for detecting respiratory syncytial virus infection
CN117586358A (en) * 2024-01-19 2024-02-23 北京安百胜生物科技有限公司 Respiratory Syncytial Virus (RSV) polypeptides having immunogenicity

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Also Published As

Publication number Publication date
EP3010931A1 (en) 2016-04-27
MX2015017771A (en) 2016-10-04
BR112015031509B1 (en) 2023-05-09
AU2014283334B2 (en) 2018-10-18
EA201690031A1 (en) 2016-07-29
EA034653B1 (en) 2020-03-03
AU2014283334A1 (en) 2015-12-17
CN105408348A (en) 2016-03-16
WO2014202570A1 (en) 2014-12-24
IL243053B (en) 2020-06-30
CL2015003655A1 (en) 2016-06-03
AP2015008893A0 (en) 2015-12-31
JP2016522230A (en) 2016-07-28
JP6679475B2 (en) 2020-04-15
PH12015502735A1 (en) 2016-03-07
US20160176932A1 (en) 2016-06-23
CA2914792A1 (en) 2014-12-24
MX362792B (en) 2019-02-13
BR112015031509A2 (en) 2017-08-29
MY171210A (en) 2019-10-02
PH12015502735B1 (en) 2016-03-07
KR20160021196A (en) 2016-02-24
US10294279B2 (en) 2019-05-21
EP3010931B1 (en) 2018-06-13
ZA201509140B (en) 2022-03-30
CA2914792C (en) 2024-02-27
HK1223949A1 (en) 2017-08-11
CN105408348B (en) 2021-07-06
KR102313153B1 (en) 2021-10-15
PE20160045A1 (en) 2016-02-18
NZ714594A (en) 2021-07-30

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