CA2496918A1 - Procedes chromatographiques de purification d'adenovirus - Google Patents

Procedes chromatographiques de purification d'adenovirus Download PDF

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Publication number
CA2496918A1
CA2496918A1 CA002496918A CA2496918A CA2496918A1 CA 2496918 A1 CA2496918 A1 CA 2496918A1 CA 002496918 A CA002496918 A CA 002496918A CA 2496918 A CA2496918 A CA 2496918A CA 2496918 A1 CA2496918 A1 CA 2496918A1
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CA
Canada
Prior art keywords
medium
adenovirus
media
cells
chromatographic medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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CA002496918A
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English (en)
Inventor
Joseph Senesac
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Introgen Therapeutics Inc
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2496918A1 publication Critical patent/CA2496918A1/fr
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne des procédés permettant de faire passer des préparations de particules d'adénovirus à travers un milieu chromatographique afin de fournir des particules d'adénovirus purifiées.
CA002496918A 2002-08-28 2003-08-27 Procedes chromatographiques de purification d'adenovirus Abandoned CA2496918A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40659102P 2002-08-28 2002-08-28
US60/406,591 2002-08-28
PCT/US2003/026831 WO2004020971A2 (fr) 2002-08-28 2003-08-27 Procedes chromatographiques de purification d'adenovirus

Publications (1)

Publication Number Publication Date
CA2496918A1 true CA2496918A1 (fr) 2004-03-11

Family

ID=31978321

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002496918A Abandoned CA2496918A1 (fr) 2002-08-28 2003-08-27 Procedes chromatographiques de purification d'adenovirus

Country Status (5)

Country Link
US (1) US20040106184A1 (fr)
EP (1) EP1585964A4 (fr)
AU (1) AU2003268210A1 (fr)
CA (1) CA2496918A1 (fr)
WO (1) WO2004020971A2 (fr)

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WO2007059473A2 (fr) * 2005-11-12 2007-05-24 Introgen Therapeutics, Inc. Procedes de production et de purification de vecteurs adenoviraux
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WO2009123657A1 (fr) * 2008-04-01 2009-10-08 University Of North Carolina At Charlotte Ensemble bioréacteur et procédés associés
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EP2988780B1 (fr) 2013-04-25 2018-12-26 Janssen Vaccines & Prevention B.V. Polypeptides préfusion rsv f solubles et stabilisée
CN105408348B (zh) 2013-06-17 2021-07-06 扬森疫苗与预防公司 稳定化的可溶性融合前rsv f多肽
EP3054007A1 (fr) * 2015-02-09 2016-08-10 Institut National De La Sante Et De La Recherche Medicale (Inserm) Purification de particules de virus adéno-associés de recombinaison comprenant une étape de purification par affinité immunologique
EP3054006A1 (fr) 2015-02-09 2016-08-10 Institut National De La Sante Et De La Recherche Medicale (Inserm) Purification de particule de virus adéno-associé recombinant avec une chromatographie à échange d'anions en plusieurs étapes
EP3283634B1 (fr) 2015-04-14 2019-05-22 Janssen Vaccines & Prevention B.V. Adénovirus recombinant exprimant deux transgènes comprenant un promoteur bidirectionnel
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JP2020519663A (ja) 2017-05-17 2020-07-02 ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． Ｒｓｖ感染に対する防御免疫を誘導するための方法及び組成物
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CN108593823B (zh) * 2018-04-04 2020-10-09 桂林理工大学 一种分离富集大体积水样中三嗪类农药的方法
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Also Published As

Publication number Publication date
EP1585964A2 (fr) 2005-10-19
WO2004020971A2 (fr) 2004-03-11
US20040106184A1 (en) 2004-06-03
WO2004020971A3 (fr) 2007-11-08
EP1585964A4 (fr) 2008-07-16
AU2003268210A8 (en) 2004-03-19
AU2003268210A1 (en) 2004-03-19

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