CN105408348B - 稳定化的可溶性融合前rsv f多肽 - Google Patents

稳定化的可溶性融合前rsv f多肽 Download PDF

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CN105408348B
CN105408348B CN201480034307.1A CN201480034307A CN105408348B CN 105408348 B CN105408348 B CN 105408348B CN 201480034307 A CN201480034307 A CN 201480034307A CN 105408348 B CN105408348 B CN 105408348B
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CN105408348A (zh
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J·P·M·朗热戴克
A·克拉鲁普
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    • C07K2319/00Fusion polypeptide
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    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
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CN201480034307.1A 2013-06-17 2014-06-17 稳定化的可溶性融合前rsv f多肽 Active CN105408348B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13172256.3 2013-06-17
EP13172256 2013-06-17
PCT/EP2014/062655 WO2014202570A1 (fr) 2013-06-17 2014-06-17 Polypeptides f solubles et stabilisés du vrs en conformation pré-fusion

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CN105408348A CN105408348A (zh) 2016-03-16
CN105408348B true CN105408348B (zh) 2021-07-06

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US (1) US10294279B2 (fr)
EP (1) EP3010931B1 (fr)
JP (1) JP6679475B2 (fr)
KR (1) KR102313153B1 (fr)
CN (1) CN105408348B (fr)
AP (1) AP2015008893A0 (fr)
AU (1) AU2014283334B2 (fr)
BR (1) BR112015031509B1 (fr)
CA (1) CA2914792C (fr)
CL (1) CL2015003655A1 (fr)
EA (1) EA034653B1 (fr)
HK (1) HK1223949A1 (fr)
IL (1) IL243053B (fr)
MX (1) MX362792B (fr)
MY (1) MY171210A (fr)
PE (1) PE20160045A1 (fr)
PH (1) PH12015502735A1 (fr)
SG (1) SG11201510216RA (fr)
WO (1) WO2014202570A1 (fr)
ZA (1) ZA201509140B (fr)

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AP2015008815A0 (en) 2013-04-25 2015-10-31 Crucell Holland Bv Stabilized soluble prefusion rsv f polypeptides
PE20160045A1 (es) 2013-06-17 2016-02-18 Crucell Holland Bv Polipeptidos f de prefusion del virus sincicial respiratorio (rsv) solubles y estabilizados
CN116059336A (zh) 2015-07-07 2023-05-05 扬森疫苗与预防公司 针对rsv的疫苗
WO2017005848A1 (fr) 2015-07-07 2017-01-12 Janssen Vaccines & Prevention B.V. Polypeptides f du vrs de pré-fusion solubles stabilisés
RU2723039C2 (ru) 2015-12-23 2020-06-08 Пфайзер Инк. Мутанты белка f rsv
KR102401247B1 (ko) 2016-04-05 2022-05-25 얀센 백신스 앤드 프리벤션 비.브이. Rsv에 대한 백신
SI3439672T1 (sl) 2016-04-05 2021-02-26 Janssen Vaccines & Prevention B.V. Stabiliziran topen pre-fuzijski F protein RSV za uporabo v profilaksi okužbe z RSV
WO2017207477A1 (fr) 2016-05-30 2017-12-07 Janssen Vaccines & Prevention B.V. Protéines f du vrs de pré-fusion solubles stabilisées
MX2018014699A (es) 2016-05-30 2019-02-28 Janssen Vaccines & Prevention Bv Proteinas f de prefusion del vrs estabilizadas.
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CN114502572A (zh) 2019-09-04 2022-05-13 华盛顿大学 展示副粘病毒和/或肺炎病毒f蛋白的自组装蛋白纳米结构及其用途
AU2021250630A1 (en) 2020-04-02 2022-10-20 Janssen Vaccines & Prevention B.V. Stabilized vaccine compositions
JP2022060169A (ja) 2020-10-02 2022-04-14 ファイザー・インク Rsv fタンパク質生産のための細胞培養工程
CN115161344A (zh) * 2022-04-26 2022-10-11 北京智飞绿竹生物制药有限公司 一种针对呼吸道合胞病毒感染的疫苗的制备方法
WO2024067725A1 (fr) * 2022-09-29 2024-04-04 北京百邑无忧科技发展有限公司 Protéine de fusion recombinante du virus respiratoire syncytial à conformation de préfusion, son procédé de préparation et son utilisation
WO2024067723A1 (fr) * 2022-09-29 2024-04-04 北京百邑无忧科技发展有限公司 Protéine de fusion recombinante du virus respiratoire syncytial ayant une conformation de pré-fusion, son procédé de préparation et son utilisation
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