SG11201508186XA - Phosphoketolases for improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precursors, and isoprenoids - Google Patents
Phosphoketolases for improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precursors, and isoprenoidsInfo
- Publication number
- SG11201508186XA SG11201508186XA SG11201508186XA SG11201508186XA SG11201508186XA SG 11201508186X A SG11201508186X A SG 11201508186XA SG 11201508186X A SG11201508186X A SG 11201508186XA SG 11201508186X A SG11201508186X A SG 11201508186XA SG 11201508186X A SG11201508186X A SG 11201508186XA
- Authority
- SG
- Singapore
- Prior art keywords
- phosphoketolases
- isoprenoids
- isoprene
- improved production
- acetyl coenzyme
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/02—Aldehyde-lyases (4.1.2)
- C12Y401/02009—Phosphoketolase (4.1.2.9)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361810696P | 2013-04-10 | 2013-04-10 | |
US201361834359P | 2013-06-12 | 2013-06-12 | |
PCT/US2014/033688 WO2014169144A2 (en) | 2013-04-10 | 2014-04-10 | Phosphoketolases foe improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precurosors, and isoprenoids |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201508186XA true SG11201508186XA (en) | 2015-11-27 |
Family
ID=50877659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201508186XA SG11201508186XA (en) | 2013-04-10 | 2014-04-10 | Phosphoketolases for improved production of acetyl coenzyme a-derived metabolites, isoprene, isoprenoid precursors, and isoprenoids |
Country Status (8)
Country | Link |
---|---|
US (3) | US10246694B2 (zh) |
EP (2) | EP3425049A1 (zh) |
JP (2) | JP6530375B2 (zh) |
CN (1) | CN105555952A (zh) |
BR (1) | BR112015025489A2 (zh) |
ES (1) | ES2735331T3 (zh) |
SG (1) | SG11201508186XA (zh) |
WO (1) | WO2014169144A2 (zh) |
Families Citing this family (12)
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US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
ES2735331T3 (es) | 2013-04-10 | 2019-12-18 | Goodyear Tire & Rubber | Fosfocetolasas para mejorar la producción de metabolitos derivados de acetil-coenzima A, isopreno, precursores de isoprenoides e isoprenoides |
DK3194604T3 (da) * | 2014-09-18 | 2020-05-25 | Genomatica Inc | Ikke-naturlig mikrobielle organismer med forbedret energisk effektivitet |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US20200377559A1 (en) * | 2017-03-24 | 2020-12-03 | Danisco Us Inc | Reduction of acetate and glycerol in modified yeast having an exogenous ethanol-producing pathway |
CN107841523A (zh) * | 2017-10-19 | 2018-03-27 | 浙江大学 | 利用群体感应分子诱导从桦褐孔菌中提取三萜类物质方法 |
JP2021505154A (ja) | 2017-12-07 | 2021-02-18 | ザイマージェン インコーポレイテッド | 発酵によって(6e)−8−ヒドロキシゲラニオールを生産するための設計された生合成経路 |
EP3728212A1 (en) | 2017-12-21 | 2020-10-28 | Zymergen Inc. | Nepetalactol oxidoreductases, nepetalactol synthases, and microbes capable of producing nepetalactone |
WO2019166647A1 (en) * | 2018-03-01 | 2019-09-06 | Total Raffinage Chimie | Metabolic pathways with increased carbon yield |
CN109929883A (zh) * | 2019-04-02 | 2019-06-25 | 烟台华康荣赞生物科技有限公司 | 重组酵母、构建方法和其在制备酪醇及衍生物中的应用 |
WO2021063958A1 (en) * | 2019-09-30 | 2021-04-08 | Global Bioenergies | Improved means and methods for increasing the yield of acetyl-coa from glucose |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
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FR669447A (fr) | 1929-02-09 | 1929-11-15 | Dispositif pour arrêter automatiquement un moteur d'automobile après une période de temps prédéterminée | |
DE19629568C1 (de) | 1996-07-15 | 1998-01-08 | Fraunhofer Ges Forschung | Verfahren zur Herstellung von Isopren |
US7172886B2 (en) | 2001-12-06 | 2007-02-06 | The Regents Of The University Of California | Biosynthesis of isopentenyl pyrophosphate |
WO2003095651A1 (fr) | 2002-05-10 | 2003-11-20 | Kyowa Hakko Kogyo Co., Ltd. | Procede de production d'acide mevalonique |
KR101148255B1 (ko) | 2002-10-04 | 2012-08-08 | 다니스코 유에스 인크. | 고수율을 갖는 1,3-프로판디올의 생물학적 제조 방법 |
RU2004124226A (ru) * | 2004-08-10 | 2006-01-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | Использование фосфокетолазы для продукции полезных метаболитов |
ES2341264T3 (es) * | 2004-08-10 | 2010-06-17 | Ajinomoto Co., Inc. | El uso de fosfocetolasa para producir metabolitos utiles. |
MY146612A (en) | 2006-05-26 | 2012-09-14 | Amyris Inc | Production of isoprenoids |
JP4986547B2 (ja) | 2006-09-04 | 2012-07-25 | 株式会社Adeka | 新規なアセトアセチルCoA合成酵素、それをコードするDNA配列、当該酵素の製造方法および当該酵素を利用したメバロン酸の製造方法 |
WO2009005704A1 (en) * | 2007-07-03 | 2009-01-08 | The Regents Of The University Of California | Methods of increasing isoprenoid or isoprenoid precursor production |
SG162265A1 (en) | 2007-12-13 | 2010-07-29 | Danisco Us Inc | Compositions and methods for producing isoprene |
WO2009100231A2 (en) | 2008-02-06 | 2009-08-13 | The Regents Of The University Of California | Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi |
US8173410B2 (en) | 2008-04-23 | 2012-05-08 | Danisco Us Inc. | Isoprene synthase variants for improved microbial production of isoprene |
US7632995B2 (en) | 2008-05-09 | 2009-12-15 | Monsanto Technology Llc | Plants and seeds of hybrid corn variety CH852179 |
MY156256A (en) | 2008-07-02 | 2016-01-29 | Danisco Us Inc | Compositions and methods for producing isoprene free of c5 hydrocarbons under decoupling conditions and/or safe operating ranges |
HU3516U (en) | 2008-07-31 | 2008-11-28 | Zoltan Kuthi | Anti-theft protection of draining for fuel tanks |
SG169640A1 (en) | 2008-09-15 | 2011-04-29 | Danisco Us Inc | Increased isoprene production using mevalonate kinase and isoprene synthase |
WO2010031068A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Reduction of carbon dioxide emission during isoprene production by fermentation |
BRPI0918453A2 (pt) | 2008-09-15 | 2019-12-17 | Danisco Us Inc | sistemas usando cultura de células para a produção de isopreno |
WO2010031062A1 (en) | 2008-09-15 | 2010-03-18 | Danisco Us Inc. | Increased isoprene production using the archaeal lower mevalonate pathway |
CA2737195A1 (en) | 2008-09-15 | 2010-03-18 | The Goodyear Tire & Rubber Company | Conversion of prenyl derivatives to isoprene |
CA2748887A1 (en) | 2008-12-30 | 2010-07-08 | Danisco Us Inc. | Methods of producing isoprene and a co-product |
US8324442B2 (en) | 2009-03-03 | 2012-12-04 | Amyris, Inc. | Microbial derived isoprene and methods for making the same |
US20100297749A1 (en) | 2009-04-21 | 2010-11-25 | Sapphire Energy, Inc. | Methods and systems for biofuel production |
WO2010124146A2 (en) | 2009-04-23 | 2010-10-28 | Danisco Us Inc. | Three-dimensional structure of isoprene synthase and its use thereof for generating variants |
JP4760951B2 (ja) | 2009-05-08 | 2011-08-31 | トヨタ自動車株式会社 | ブタノール生産能を有する組換え微生物及びブタノールの製造方法 |
TW201412988A (zh) | 2009-06-17 | 2014-04-01 | Danisco Us Inc | 使用dxp及mva途徑之改良之異戊二烯製造 |
TWI434921B (zh) | 2009-06-17 | 2014-04-21 | Danisco Us Inc | 從生物異戊二烯組合物製造燃料成分之方法及系統 |
IN2012DN01694A (zh) | 2009-09-15 | 2015-06-05 | Sapphire Energy Inc | |
JP5643838B2 (ja) | 2009-12-18 | 2014-12-17 | ダニスコ・ユーエス・インク | 再生可能資源からのイソプレンの精製 |
WO2011079314A2 (en) | 2009-12-23 | 2011-06-30 | Danisco Us Inc. | Compositions and methods of pgl for the increased production of isoprene |
US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
CN103443271A (zh) | 2010-10-27 | 2013-12-11 | 丹尼斯科美国公司 | 用于增加异戊二烯产量的异戊二烯合酶变体 |
ES2699747T3 (es) * | 2011-04-29 | 2019-02-12 | Danisco Us Inc | Microorganismos recombinantes para la producción potenciada de mevalonato, isopreno e isoprenoides |
JP2014519811A (ja) * | 2011-04-29 | 2014-08-21 | ダニスコ・ユーエス・インク | チオラーゼ、HMG−CoA合成酵素及びHMG−CoA還元酵素活性を有するポリペプチドをコードしている遺伝子を使用するメバロン酸、イソプレン、及びイソプレノイドの生産 |
RU2658770C2 (ru) | 2011-07-12 | 2018-06-22 | Сайентист Оф Фортчун С.А. | Рекомбинантный микроорганизм для получения полезных метаболитов |
DK2764084T4 (da) | 2011-10-07 | 2021-12-06 | Danisco Us Inc | Anvendelse af phosphoketolase i fremstillingen af mevalonat, isoprenoid-udgangsstoffer, og isopren |
US8415136B1 (en) * | 2011-11-09 | 2013-04-09 | Amyris, Inc. | Production of acetyl-coenzyme a derived isoprenoids |
JP2015516173A (ja) | 2012-05-16 | 2015-06-11 | グリコス バイオテクノロジーズ インコーポレイテッドGlycos Biotechnologies, Inc. | イソプレン生産用微生物およびプロセス |
ES2735331T3 (es) | 2013-04-10 | 2019-12-18 | Goodyear Tire & Rubber | Fosfocetolasas para mejorar la producción de metabolitos derivados de acetil-coenzima A, isopreno, precursores de isoprenoides e isoprenoides |
-
2014
- 2014-04-10 ES ES14727659T patent/ES2735331T3/es active Active
- 2014-04-10 CN CN201480032280.2A patent/CN105555952A/zh active Pending
- 2014-04-10 SG SG11201508186XA patent/SG11201508186XA/en unknown
- 2014-04-10 EP EP18175724.6A patent/EP3425049A1/en not_active Withdrawn
- 2014-04-10 EP EP14727659.6A patent/EP2984105B1/en active Active
- 2014-04-10 WO PCT/US2014/033688 patent/WO2014169144A2/en active Application Filing
- 2014-04-10 JP JP2016507665A patent/JP6530375B2/ja active Active
- 2014-04-10 US US14/783,391 patent/US10246694B2/en active Active
- 2014-04-10 BR BR112015025489A patent/BR112015025489A2/pt not_active Application Discontinuation
-
2019
- 2019-02-14 US US16/276,558 patent/US10988750B2/en active Active
- 2019-05-16 JP JP2019093057A patent/JP2019162130A/ja active Pending
-
2020
- 2020-09-24 US US16/948,592 patent/US11371035B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2984105A2 (en) | 2016-02-17 |
BR112015025489A2 (pt) | 2017-10-10 |
EP2984105B1 (en) | 2019-05-22 |
EP3425049A1 (en) | 2019-01-09 |
WO2014169144A2 (en) | 2014-10-16 |
JP2019162130A (ja) | 2019-09-26 |
WO2014169144A3 (en) | 2014-12-04 |
US10246694B2 (en) | 2019-04-02 |
JP6530375B2 (ja) | 2019-06-12 |
JP2016519577A (ja) | 2016-07-07 |
US10988750B2 (en) | 2021-04-27 |
ES2735331T3 (es) | 2019-12-18 |
CN105555952A (zh) | 2016-05-04 |
US20190367896A1 (en) | 2019-12-05 |
US20160068831A1 (en) | 2016-03-10 |
US11371035B2 (en) | 2022-06-28 |
WO2014169144A8 (en) | 2015-10-15 |
US20210139878A1 (en) | 2021-05-13 |
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