SG11201505462YA - Compounds and methods for treating bacterial infections - Google Patents

Compounds and methods for treating bacterial infections

Info

Publication number
SG11201505462YA
SG11201505462YA SG11201505462YA SG11201505462YA SG11201505462YA SG 11201505462Y A SG11201505462Y A SG 11201505462YA SG 11201505462Y A SG11201505462Y A SG 11201505462YA SG 11201505462Y A SG11201505462Y A SG 11201505462YA SG 11201505462Y A SG11201505462Y A SG 11201505462YA
Authority
SG
Singapore
Prior art keywords
compounds
methods
bacterial infections
treating bacterial
treating
Prior art date
Application number
SG11201505462YA
Other languages
English (en)
Inventor
Gregory Steven Basarab
Madhusudhan Reddy Gowravaram
Sheila Irene Hauck
Fei Zhou
Original Assignee
Entasis Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Entasis Therapeutics Ltd filed Critical Entasis Therapeutics Ltd
Publication of SG11201505462YA publication Critical patent/SG11201505462YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SG11201505462YA 2013-01-23 2014-01-22 Compounds and methods for treating bacterial infections SG11201505462YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361755537P 2013-01-23 2013-01-23
US201361859910P 2013-07-30 2013-07-30
PCT/GB2014/050164 WO2014114929A1 (en) 2013-01-23 2014-01-22 Compounds and methods for treating bacterial infections

Publications (1)

Publication Number Publication Date
SG11201505462YA true SG11201505462YA (en) 2015-08-28

Family

ID=50033593

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201505462YA SG11201505462YA (en) 2013-01-23 2014-01-22 Compounds and methods for treating bacterial infections

Country Status (31)

Country Link
US (4) US8889671B2 (es)
EP (1) EP2948461B1 (es)
JP (1) JP6285960B2 (es)
KR (1) KR102149567B1 (es)
CN (1) CN105229012B (es)
AR (1) AR094565A1 (es)
AU (1) AU2014208965B2 (es)
BR (1) BR112015017519B1 (es)
CA (1) CA2897887C (es)
CY (1) CY1122805T1 (es)
DK (1) DK2948461T3 (es)
EA (1) EA026901B1 (es)
ES (1) ES2780824T3 (es)
HK (1) HK1218293A1 (es)
HR (1) HRP20200401T1 (es)
HU (1) HUE048990T2 (es)
IL (1) IL239860A0 (es)
LT (1) LT2948461T (es)
ME (1) ME03676B (es)
MX (1) MX360650B (es)
MY (1) MY192765A (es)
NZ (1) NZ710091A (es)
PH (1) PH12015501588B1 (es)
PL (1) PL2948461T3 (es)
PT (1) PT2948461T (es)
RS (1) RS60078B1 (es)
SG (1) SG11201505462YA (es)
SI (1) SI2948461T1 (es)
TW (1) TWI603973B (es)
UY (1) UY35274A (es)
WO (1) WO2014114929A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9040528B2 (en) * 2008-10-14 2015-05-26 Astrazeneca Ab Chemical compounds 542
US8889671B2 (en) * 2013-01-23 2014-11-18 Astrazeneca Ab Compounds and methods for treating bacterial infections
SG10201906842WA (en) * 2014-05-29 2019-08-27 Entasis Therapeutics Ltd Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections
US10660933B2 (en) * 2015-10-29 2020-05-26 University Of Maryland, College Park Compositions and methods for inhibition of bacterial infections in human endocervix
CN106632298B (zh) 2015-11-03 2021-06-01 上海科胜药物研发有限公司 一种泰地唑胺的制备方法及其中间体
SI3630752T1 (sl) 2017-06-01 2021-10-29 Bristol Myers Squibb Co Spojine vsebujoče substituiran dušik
CN109111465B (zh) * 2017-06-22 2021-01-12 中国科学院上海药物研究所 噻唑烷酮螺嘧啶三酮类化合物及制备方法和用途
WO2018233670A1 (zh) * 2017-06-22 2018-12-27 中国科学院上海药物研究所 苯并异噁唑螺嘧啶三酮类化合物及制备方法和用途
CN109111466B (zh) * 2017-06-22 2022-08-02 中国科学院上海药物研究所 苯并异噁唑螺嘧啶三酮类化合物及制备方法和用途
CN108060207B (zh) * 2017-12-29 2021-10-15 河南科技大学 一种基于微量天然化合物的最小杀菌浓度测定方法
US11905286B2 (en) 2018-08-09 2024-02-20 Antabio Sas Diazabicyclooctanones as inhibitors of serine beta-lactamases
CN111559985A (zh) * 2020-05-13 2020-08-21 河南科技大学第一附属医院 具有杀菌作用的噁唑酮类化合物及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759570B2 (ja) 1986-05-06 1995-06-28 三井東圧化学株式会社 2−オキサゾリジノン類の製造方法
US7208490B2 (en) 2002-10-07 2007-04-24 Pharmacia & Upjohn Company Llc Tricyclic tetrahydroquinoline antibacterial agents
US7371757B2 (en) 2003-08-15 2008-05-13 Astrazeneca Ab Fused heterocycles as inhibitors of glutamate racemase(MURI)
WO2005066119A2 (en) 2003-12-31 2005-07-21 Schering-Plough Ltd. Antibacterial 1-(4-mono-and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoropropanols and preparation thereof
EP1888597A2 (en) 2005-05-09 2008-02-20 Warner-Lambert Company LLC Antibacterial agents
DOP2006000268A (es) 2005-12-22 2007-07-31 Pfizer Prod Inc Agentes antibacterianos
CL2007003332A1 (es) * 2006-11-24 2008-06-20 Actelion Pharmaceuticals Ltd Compuestos derivados de heterociclos condensados; compuestos intermediarios; composicion farmaceutica; y uso en la prevencion o tratamiento de infecciones bacterianas.
RU2010103101A (ru) 2007-07-02 2011-08-10 Астразенека Аб (Se) Химические соединения
US9040528B2 (en) 2008-10-14 2015-05-26 Astrazeneca Ab Chemical compounds 542
EP2350077B1 (en) * 2008-10-14 2016-01-27 Entasis Therapeutics Limited Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections
US8952149B2 (en) 2012-09-26 2015-02-10 Zoetis Llc Tricyclic tetrahydroquinoline antibacterial agents
US8889671B2 (en) * 2013-01-23 2014-11-18 Astrazeneca Ab Compounds and methods for treating bacterial infections

Also Published As

Publication number Publication date
PH12015501588A1 (en) 2015-10-05
US8889671B2 (en) 2014-11-18
IL239860A0 (en) 2015-08-31
US20170128458A1 (en) 2017-05-11
CA2897887C (en) 2021-09-07
HRP20200401T1 (hr) 2020-06-12
NZ710091A (en) 2019-08-30
CY1122805T1 (el) 2021-05-05
UY35274A (es) 2014-07-31
EA201591362A1 (ru) 2015-11-30
EP2948461A1 (en) 2015-12-02
WO2014114929A1 (en) 2014-07-31
EP2948461B1 (en) 2019-12-25
US9839641B2 (en) 2017-12-12
AR094565A1 (es) 2015-08-12
DK2948461T3 (en) 2020-02-17
PL2948461T3 (pl) 2020-09-07
HK1218293A1 (zh) 2017-02-10
CN105229012A (zh) 2016-01-06
TWI603973B (zh) 2017-11-01
BR112015017519B1 (pt) 2021-01-19
US9540394B2 (en) 2017-01-10
HUE048990T2 (hu) 2020-09-28
PT2948461T (pt) 2020-03-31
KR102149567B1 (ko) 2020-08-28
JP6285960B2 (ja) 2018-02-28
PH12015501588B1 (en) 2015-10-05
US9187495B2 (en) 2015-11-17
MY192765A (en) 2022-09-07
MX360650B (es) 2018-11-12
TW201443063A (zh) 2014-11-16
LT2948461T (lt) 2020-03-25
AU2014208965B2 (en) 2017-07-27
US20150203513A1 (en) 2015-07-23
AU2014208965A1 (en) 2015-07-30
ME03676B (me) 2020-10-20
MX2015009479A (es) 2016-03-04
CN105229012B (zh) 2017-07-18
BR112015017519A2 (pt) 2017-11-21
US20140206677A1 (en) 2014-07-24
SI2948461T1 (sl) 2020-06-30
CA2897887A1 (en) 2014-07-31
KR20150107875A (ko) 2015-09-23
US20160130281A1 (en) 2016-05-12
RS60078B1 (sr) 2020-05-29
EA026901B1 (ru) 2017-05-31
JP2016506922A (ja) 2016-03-07
ES2780824T3 (es) 2020-08-27

Similar Documents

Publication Publication Date Title
HK1225649A1 (zh) 用於治療細菌性感染的化合物和方法
EP2991638A4 (en) METHODS OF TREATING BACTERIAL INFECTIONS
HK1216389A1 (zh) 治療局部微生物感染的方法
IL246087A0 (en) Materials and methods for controlling inflammation
HK1218293A1 (zh) 治療細菌感染的化合物和方法
EP2991968A4 (en) Compounds and methods of treating infections
EP2953624A4 (en) METHOD FOR THE TREATMENT OF MICROBIAL INFECTIONS, INCLUDING MASTITIS
IL242770B (en) A therapeutic combination that includes oxazolidinone-quinolones for use in the treatment of bacterial infections
EP2994140A4 (en) Methods for treating hcv infection
HK1215164A1 (zh) 處理方法
EP3060216A4 (en) Methods for treating hcv
GB201212588D0 (en) Colicins for treating bacterial infections
HK1213268A1 (zh) 用於治療細菌感染的甘露糖衍生物
EP3065550A4 (en) Methods and compositions for treating sepsis
ZA201503474B (en) Compositions and methods for treating bacterial infections
EP2969003A4 (en) METHOD AND COMPOSITIONS FOR BACTERIAL INFECTIONS
EP2968497A4 (en) COMPOSITIONS AND METHODS FOR TREATING FUNGAL AND BACTERIAL PATHOGENIC AGENTS
EP2947462A4 (en) SAMPLE PROCESSING SYSTEM
IL249616A0 (en) Methods for treating inflammation
IL246185A0 (en) Methods and compositions for treating dysregulation in systems
EP3038615A4 (en) Methods for treating bacterial infections using oritavancin and polymyxins
GB201311984D0 (en) Methods and compounds for preventing or treating osteoarthritis
AU2013901517A0 (en) Methods of Treating Bacterial Infections
AU2013901516A0 (en) Compounds and Methods of Treating Infections
TH1501004125A (th) สารประกอบและวิธีการสำหรับการรักษาการติดเชื้อแบคทีเรีย