SG11201502149YA - Coumarin derivative - Google Patents

Coumarin derivative

Info

Publication number
SG11201502149YA
SG11201502149YA SG11201502149YA SG11201502149YA SG11201502149YA SG 11201502149Y A SG11201502149Y A SG 11201502149YA SG 11201502149Y A SG11201502149Y A SG 11201502149YA SG 11201502149Y A SG11201502149Y A SG 11201502149YA SG 11201502149Y A SG11201502149Y A SG 11201502149YA
Authority
SG
Singapore
Prior art keywords
coumarin derivative
coumarin
derivative
Prior art date
Application number
SG11201502149YA
Other languages
English (en)
Inventor
Mitsuru Naiki
Tomoyuki Okada
Kazuyoshi Sawada
Takashi Ogino
Original Assignee
Nippon Zoki Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Zoki Pharmaceutical Co filed Critical Nippon Zoki Pharmaceutical Co
Publication of SG11201502149YA publication Critical patent/SG11201502149YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/12Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
SG11201502149YA 2012-09-21 2013-09-20 Coumarin derivative SG11201502149YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012208656 2012-09-21
PCT/JP2013/075414 WO2014046224A1 (ja) 2012-09-21 2013-09-20 クマリン誘導体

Publications (1)

Publication Number Publication Date
SG11201502149YA true SG11201502149YA (en) 2015-05-28

Family

ID=50341526

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201502149YA SG11201502149YA (en) 2012-09-21 2013-09-20 Coumarin derivative

Country Status (15)

Country Link
US (1) US9365533B2 (ko)
EP (1) EP2899187B1 (ko)
JP (1) JP6091016B2 (ko)
KR (1) KR20150056544A (ko)
CN (1) CN104640849B (ko)
AU (1) AU2013318962B2 (ko)
BR (1) BR112015005973A2 (ko)
CA (1) CA2885262A1 (ko)
ES (1) ES2630068T3 (ko)
HK (1) HK1211918A1 (ko)
IL (1) IL237823A (ko)
RU (1) RU2646756C2 (ko)
SG (1) SG11201502149YA (ko)
TW (1) TWI583677B (ko)
WO (1) WO2014046224A1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160127749A (ko) 2014-03-20 2016-11-04 니폰 조키 세야쿠 가부시키가이샤 쿠마린 유도체를 유효 성분으로서 함유하는 치료·예방제
JP6089055B2 (ja) * 2014-03-20 2017-03-01 日本臓器製薬株式会社 クマリン誘導体を含有する医薬

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1523317A (fr) * 1967-03-20 1968-05-03 Lipha Nouveaux dérivés hydroxylés de la coumarine et leurs procédés de préparation
FR2543140B1 (fr) * 1983-03-24 1985-06-21 Cortial Nouveaux acides flavone-carboxyliques-4', leur methode de preparation et leur application en therapeutique
RU2036917C1 (ru) * 1989-11-28 1995-06-09 Санкио Компани Лимитед Производные кумарина или их фармацевтически приемлемая соль
DK0550493T3 (da) * 1990-09-28 1996-03-11 Upjohn Co Anthelmintiske og anticoccidiske 3-carbamoyl-4-hydroxycoumariner, fremgangsmåde til deres anvendelse og sammensætninger
CA2159192C (en) 1993-04-09 2006-07-25 Keiichi Tanaka Immunomodulator cell adhesion inhibitor, and agent for treating and preventing autoimmune diseases
AU711986B2 (en) * 1996-05-15 1999-10-28 Hoechst Aktiengesellschaft Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them
US6191164B1 (en) * 1996-05-15 2001-02-20 Hoechst Aktiengesellschaft Sulfonamide-substituted chromans, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them
JP4658512B2 (ja) * 2004-04-27 2011-03-23 日本臓器製薬株式会社 クマリン誘導体及び該誘導体を含有するメイラード反応阻害剤
DE102004063910B4 (de) * 2004-07-05 2006-12-28 Bioplanta Arzneimittel Gmbh Trisubstituierte Benzopyranone sowie diese enthaltende Pflanzenextrakte und Mittel
KR101511396B1 (ko) 2007-07-20 2015-04-13 추가이 세이야쿠 가부시키가이샤 p27 단백질 유도제

Also Published As

Publication number Publication date
ES2630068T3 (es) 2017-08-17
CN104640849A (zh) 2015-05-20
RU2015114480A (ru) 2016-11-10
TWI583677B (zh) 2017-05-21
CA2885262A1 (en) 2014-03-27
TW201418239A (zh) 2014-05-16
US9365533B2 (en) 2016-06-14
AU2013318962A1 (en) 2015-04-16
US20150232440A1 (en) 2015-08-20
JP6091016B2 (ja) 2017-03-08
JPWO2014046224A1 (ja) 2016-08-18
EP2899187B1 (en) 2017-04-19
IL237823A (en) 2017-05-29
WO2014046224A1 (ja) 2014-03-27
CN104640849B (zh) 2016-10-26
AU2013318962B2 (en) 2017-03-02
EP2899187A4 (en) 2016-06-29
EP2899187A1 (en) 2015-07-29
HK1211918A1 (en) 2016-06-03
RU2646756C2 (ru) 2018-03-07
BR112015005973A2 (pt) 2017-07-04
KR20150056544A (ko) 2015-05-26

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