SG11201404789XA - Sequence symmetric modified igg4 bispecific antibodies - Google Patents

Sequence symmetric modified igg4 bispecific antibodies

Info

Publication number
SG11201404789XA
SG11201404789XA SG11201404789XA SG11201404789XA SG11201404789XA SG 11201404789X A SG11201404789X A SG 11201404789XA SG 11201404789X A SG11201404789X A SG 11201404789XA SG 11201404789X A SG11201404789X A SG 11201404789XA SG 11201404789X A SG11201404789X A SG 11201404789XA
Authority
SG
Singapore
Prior art keywords
bispecific antibodies
modified igg4
igg4 bispecific
symmetric modified
sequence symmetric
Prior art date
Application number
SG11201404789XA
Other languages
English (en)
Inventor
David Paul Humphreys
Shirley Jane Peters
Original Assignee
Ucb Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Pharma Sa filed Critical Ucb Pharma Sa
Publication of SG11201404789XA publication Critical patent/SG11201404789XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/522—CH1 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/53—Hinge

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201404789XA 2012-02-22 2013-02-22 Sequence symmetric modified igg4 bispecific antibodies SG11201404789XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1203051.6A GB201203051D0 (en) 2012-02-22 2012-02-22 Biological products
PCT/EP2013/053614 WO2013124450A1 (en) 2012-02-22 2013-02-22 Sequence symmetric modified igg4 bispecific antibodies

Publications (1)

Publication Number Publication Date
SG11201404789XA true SG11201404789XA (en) 2014-09-26

Family

ID=45940018

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201404789XA SG11201404789XA (en) 2012-02-22 2013-02-22 Sequence symmetric modified igg4 bispecific antibodies

Country Status (16)

Country Link
US (2) US10221251B2 (zh)
EP (2) EP2817332B1 (zh)
JP (2) JP6308952B2 (zh)
KR (2) KR20200018706A (zh)
CN (2) CN104321341B (zh)
AU (2) AU2013224003B2 (zh)
CA (1) CA2864439C (zh)
DK (2) DK3156416T3 (zh)
EA (1) EA035050B1 (zh)
ES (2) ES2599503T3 (zh)
GB (1) GB201203051D0 (zh)
HK (1) HK1202563A1 (zh)
IL (1) IL234102B (zh)
MX (1) MX356288B (zh)
SG (1) SG11201404789XA (zh)
WO (1) WO2013124450A1 (zh)

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Also Published As

Publication number Publication date
CN108586615A (zh) 2018-09-28
EP3156416A1 (en) 2017-04-19
JP6308952B2 (ja) 2018-04-11
KR20200018706A (ko) 2020-02-19
KR102077331B1 (ko) 2020-02-17
IL234102B (en) 2018-06-28
MX356288B (es) 2018-05-22
EP2817332A1 (en) 2014-12-31
ES2599503T3 (es) 2017-02-02
AU2018201232B2 (en) 2019-04-18
JP2015513537A (ja) 2015-05-14
GB201203051D0 (en) 2012-04-04
WO2013124450A1 (en) 2013-08-29
EP3156416B1 (en) 2019-11-20
AU2013224003A1 (en) 2014-09-18
CN108586615B (zh) 2022-03-08
US20190202937A1 (en) 2019-07-04
MX2014010018A (es) 2014-09-12
IL234102A0 (en) 2014-09-30
JP6814761B2 (ja) 2021-01-20
US10221251B2 (en) 2019-03-05
CA2864439A1 (en) 2013-08-29
HK1202563A1 (zh) 2015-10-02
CA2864439C (en) 2023-09-05
EP2817332B1 (en) 2016-07-20
ES2768780T3 (es) 2020-06-23
EA201491569A1 (ru) 2015-01-30
US11059911B2 (en) 2021-07-13
AU2013224003B2 (en) 2017-11-23
US20150018529A1 (en) 2015-01-15
AU2018201232A1 (en) 2018-03-15
KR20140127890A (ko) 2014-11-04
DK2817332T3 (en) 2016-11-07
CN104321341A (zh) 2015-01-28
CN104321341B (zh) 2018-05-22
EA035050B1 (ru) 2020-04-22
BR112014020627A2 (pt) 2020-10-27
JP2018117627A (ja) 2018-08-02
DK3156416T3 (da) 2020-02-24

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