SG10202113280XA - Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof - Google Patents
Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereofInfo
- Publication number
- SG10202113280XA SG10202113280XA SG10202113280XA SG10202113280XA SG10202113280XA SG 10202113280X A SG10202113280X A SG 10202113280XA SG 10202113280X A SG10202113280X A SG 10202113280XA SG 10202113280X A SG10202113280X A SG 10202113280XA SG 10202113280X A SG10202113280X A SG 10202113280XA
- Authority
- SG
- Singapore
- Prior art keywords
- beta
- dosage forms
- inhibitory activity
- aerosol dosage
- elastase inhibitory
- Prior art date
Links
- 239000000443 aerosol Substances 0.000 title 1
- 239000002552 dosage form Substances 0.000 title 1
- 230000002849 elastaseinhibitory effect Effects 0.000 title 1
- 239000000816 peptidomimetic Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16020210 | 2016-05-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202113280XA true SG10202113280XA (en) | 2021-12-30 |
Family
ID=56108445
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201810137UA SG11201810137UA (en) | 2016-05-31 | 2017-05-31 | Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof |
| SG10202113280XA SG10202113280XA (en) | 2016-05-31 | 2017-05-31 | Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof |
| SG11201810138XA SG11201810138XA (en) | 2016-05-31 | 2017-05-31 | Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201810137UA SG11201810137UA (en) | 2016-05-31 | 2017-05-31 | Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201810138XA SG11201810138XA (en) | 2016-05-31 | 2017-05-31 | Beta-hairpin peptidomimetic with elastase inhibitory activity and aerosol dosage forms thereof |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US11235024B2 (ko) |
| EP (2) | EP3463280B1 (ko) |
| JP (4) | JP7544466B2 (ko) |
| KR (2) | KR102480800B1 (ko) |
| CN (3) | CN116159024A (ko) |
| AU (2) | AU2017273507B2 (ko) |
| BR (2) | BR112018074551B1 (ko) |
| CA (2) | CA3024521C (ko) |
| CL (2) | CL2018003391A1 (ko) |
| DK (2) | DK3463281T3 (ko) |
| EA (2) | EA039603B1 (ko) |
| ES (2) | ES2928050T3 (ko) |
| HR (2) | HRP20221185T1 (ko) |
| HU (2) | HUE060119T2 (ko) |
| IL (2) | IL263114B2 (ko) |
| LT (2) | LT3463281T (ko) |
| MA (2) | MA45167A (ko) |
| MX (2) | MX2018014752A (ko) |
| PH (2) | PH12018502521A1 (ko) |
| PL (2) | PL3463280T3 (ko) |
| PT (2) | PT3463281T (ko) |
| RS (2) | RS63639B1 (ko) |
| SG (3) | SG11201810137UA (ko) |
| UA (2) | UA125900C2 (ko) |
| WO (2) | WO2017207117A1 (ko) |
| ZA (2) | ZA201807772B (ko) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA45167A (fr) * | 2016-05-31 | 2019-04-10 | Polyphor Ag | Peptidomimétique en épingle à cheveux bêta présentant une activité d'inhibition de l'élastase et formes pharmaceutiques aérosols correspondantes |
| MX2022002054A (es) * | 2019-08-23 | 2022-08-08 | Ph Pharma Co Ltd | Uso de un inhibidor de la elastasa de neutrofilo en la enfermedad pulmonar. |
| TW202139997A (zh) * | 2020-01-30 | 2021-11-01 | 美商維泰克斯製藥公司 | α－１抗胰蛋白酶缺乏之治療方法 |
| JP2023549971A (ja) * | 2020-11-23 | 2023-11-29 | スペクシス アーゲー | ベータヘアピン型ペプチド模倣物の組成物及びそのエアロゾル投与形態 |
| CN116421704A (zh) * | 2023-02-20 | 2023-07-14 | 成都佩德生物医药有限公司 | 多肽pd-dp-005在制备治疗肺部疾病药物中的应用及其药物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998019694A1 (en) | 1996-11-01 | 1998-05-14 | Xoma Corporation | Therapeutic uses of bpi protein products in cystic fibrosis patients |
| AU2006206272A1 (en) * | 2005-01-21 | 2006-07-27 | Alza Corporation | Therapeutic peptide formulations for coating microneedles with improved stabitity containing at least one counterion |
| NZ556747A (en) | 2005-02-17 | 2009-09-25 | Polyphor Ltd | Template-fixed beta-hairpin peptidomimetics with protease inhibitory acitivity |
| EP1712220A1 (en) * | 2005-04-15 | 2006-10-18 | PARI GmbH Spezialisten für effektive Inhalation | Pharmaceutical aerosol composition |
| WO2007091267A2 (en) | 2006-02-09 | 2007-08-16 | Kamada Ltd. | Pulmonary delivery of alpha-i proteinase inhibitor |
| CA2641827A1 (en) | 2006-02-10 | 2007-08-16 | Pari Pharma Gmbh | Nebulised antibiotics for inhalation therapy |
| WO2008025560A1 (en) * | 2006-09-01 | 2008-03-06 | Pari Pharma Gmbh | Methods for taste masking of nebulised compositions for nasal and pulmonary inhalation therapy |
| EP1927373B1 (en) | 2006-11-30 | 2012-08-22 | PARI Pharma GmbH | Inhalation nebulizer |
| PT2567691E (pt) | 2011-09-12 | 2015-04-09 | Pari Pharma Gmbh | Composições aquosas que compreendem arbecacina |
| WO2015096672A1 (zh) | 2013-12-23 | 2015-07-02 | 石家庄铁道大学 | 测试装置 |
| JP6431486B2 (ja) | 2013-12-26 | 2018-11-28 | 株式会社カネカ | 太陽電池のｉ‐ｖ測定方法、太陽電池のｉ‐ｖ測定装置、太陽電池の製造方法、太陽電池モジュールの製造方法、および太陽電池モジュール |
| HRP20221046T1 (hr) * | 2013-12-27 | 2023-01-20 | Spexis Ag | Beta-ukosni peptidomimetici kao selektivni inhibitori elastaze |
| EP3087087B1 (en) | 2013-12-27 | 2021-07-21 | Polyphor Ag | Beta-hairpin peptidomimetics as selective elastase inhibitors |
| MA45167A (fr) * | 2016-05-31 | 2019-04-10 | Polyphor Ag | Peptidomimétique en épingle à cheveux bêta présentant une activité d'inhibition de l'élastase et formes pharmaceutiques aérosols correspondantes |
-
2017
- 2017-05-31 MA MA045167A patent/MA45167A/fr unknown
- 2017-05-31 RS RS20220922A patent/RS63639B1/sr unknown
- 2017-05-31 EP EP17733737.5A patent/EP3463280B1/en active Active
- 2017-05-31 JP JP2018562549A patent/JP7544466B2/ja active Active
- 2017-05-31 LT LTEPPCT/EP2017/025157T patent/LT3463281T/lt unknown
- 2017-05-31 CA CA3024521A patent/CA3024521C/en active Active
- 2017-05-31 CN CN202211636345.7A patent/CN116159024A/zh active Pending
- 2017-05-31 DK DK17733738.3T patent/DK3463281T3/da active
- 2017-05-31 ES ES17733738T patent/ES2928050T3/es active Active
- 2017-05-31 KR KR1020187036054A patent/KR102480800B1/ko active IP Right Grant
- 2017-05-31 IL IL263114A patent/IL263114B2/en unknown
- 2017-05-31 PL PL17733737.5T patent/PL3463280T3/pl unknown
- 2017-05-31 WO PCT/EP2017/025156 patent/WO2017207117A1/en unknown
- 2017-05-31 PT PT177337383T patent/PT3463281T/pt unknown
- 2017-05-31 RS RS20220923A patent/RS63622B1/sr unknown
- 2017-05-31 EP EP17733738.3A patent/EP3463281B1/en active Active
- 2017-05-31 IL IL263112A patent/IL263112B2/en unknown
- 2017-05-31 AU AU2017273507A patent/AU2017273507B2/en active Active
- 2017-05-31 UA UAA201812930A patent/UA125900C2/uk unknown
- 2017-05-31 CN CN201780033188.1A patent/CN109310613A/zh active Pending
- 2017-05-31 US US16/305,714 patent/US11235024B2/en active Active
- 2017-05-31 MX MX2018014752A patent/MX2018014752A/es unknown
- 2017-05-31 MA MA045168A patent/MA45168A/fr unknown
- 2017-05-31 SG SG11201810137UA patent/SG11201810137UA/en unknown
- 2017-05-31 US US16/305,518 patent/US11235023B2/en active Active
- 2017-05-31 WO PCT/EP2017/025157 patent/WO2017207118A1/en unknown
- 2017-05-31 EA EA201892818A patent/EA039603B1/ru unknown
- 2017-05-31 PL PL17733738.3T patent/PL3463281T3/pl unknown
- 2017-05-31 ES ES17733737T patent/ES2927948T3/es active Active
- 2017-05-31 DK DK17733737.5T patent/DK3463280T3/da active
- 2017-05-31 HU HUE17733737A patent/HUE060119T2/hu unknown
- 2017-05-31 CN CN201780033187.7A patent/CN109195580A/zh active Pending
- 2017-05-31 BR BR112018074551-0A patent/BR112018074551B1/pt active IP Right Grant
- 2017-05-31 BR BR112018074532-4A patent/BR112018074532B1/pt active IP Right Grant
- 2017-05-31 EA EA201892819A patent/EA201892819A1/ru unknown
- 2017-05-31 LT LTEPPCT/EP2017/025156T patent/LT3463280T/lt unknown
- 2017-05-31 MX MX2018014425A patent/MX2018014425A/es unknown
- 2017-05-31 AU AU2017273508A patent/AU2017273508B2/en active Active
- 2017-05-31 PT PT177337375T patent/PT3463280T/pt unknown
- 2017-05-31 SG SG10202113280XA patent/SG10202113280XA/en unknown
- 2017-05-31 JP JP2018562561A patent/JP7286319B6/ja active Active
- 2017-05-31 CA CA3024522A patent/CA3024522C/en active Active
- 2017-05-31 KR KR1020187036055A patent/KR102511284B1/ko active IP Right Grant
- 2017-05-31 SG SG11201810138XA patent/SG11201810138XA/en unknown
- 2017-05-31 HU HUE17733738A patent/HUE060393T2/hu unknown
- 2017-05-31 UA UAA201812929A patent/UA125899C2/uk unknown
- 2017-05-31 HR HRP20221185TT patent/HRP20221185T1/hr unknown
- 2017-05-31 HR HRP20221194TT patent/HRP20221194T1/hr unknown
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2018
- 2018-11-19 ZA ZA2018/07772A patent/ZA201807772B/en unknown
- 2018-11-19 ZA ZA2018/07773A patent/ZA201807773B/en unknown
- 2018-11-28 CL CL2018003391A patent/CL2018003391A1/es unknown
- 2018-11-28 CL CL2018003390A patent/CL2018003390A1/es unknown
- 2018-11-29 PH PH12018502521A patent/PH12018502521A1/en unknown
- 2018-11-29 PH PH12018502522A patent/PH12018502522A1/en unknown
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2021
- 2021-10-06 US US17/495,137 patent/US11844823B2/en active Active
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2022
- 2022-01-04 JP JP2022000083A patent/JP2022078013A/ja active Pending
- 2022-10-20 JP JP2022168582A patent/JP2023017793A/ja not_active Withdrawn
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