MA45168A - Peptidomimétique en épingle à cheveux bêta ayant une activité inhibitrice à l'encontre de l'élastase, et ses formes posologiques en aérosol - Google Patents

Peptidomimétique en épingle à cheveux bêta ayant une activité inhibitrice à l'encontre de l'élastase, et ses formes posologiques en aérosol

Info

Publication number
MA45168A
MA45168A MA045168A MA45168A MA45168A MA 45168 A MA45168 A MA 45168A MA 045168 A MA045168 A MA 045168A MA 45168 A MA45168 A MA 45168A MA 45168 A MA45168 A MA 45168A
Authority
MA
Morocco
Prior art keywords
inhibitoring
peptidomimetic
elastase
activity
dosage forms
Prior art date
Application number
MA045168A
Other languages
English (en)
Inventor
Philip Barth
Piet Bruijnzeel
Eric Chevalier
Manfred Keller
Christian Ludin
Johann Zimmermann
Original Assignee
Polyphor Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polyphor Ag filed Critical Polyphor Ag
Publication of MA45168A publication Critical patent/MA45168A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
MA045168A 2016-05-31 2017-05-31 Peptidomimétique en épingle à cheveux bêta ayant une activité inhibitrice à l'encontre de l'élastase, et ses formes posologiques en aérosol MA45168A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16020210 2016-05-31

Publications (1)

Publication Number Publication Date
MA45168A true MA45168A (fr) 2019-04-10

Family

ID=56108445

Family Applications (2)

Application Number Title Priority Date Filing Date
MA045168A MA45168A (fr) 2016-05-31 2017-05-31 Peptidomimétique en épingle à cheveux bêta ayant une activité inhibitrice à l'encontre de l'élastase, et ses formes posologiques en aérosol
MA045167A MA45167A (fr) 2016-05-31 2017-05-31 Peptidomimétique en épingle à cheveux bêta présentant une activité d'inhibition de l'élastase et formes pharmaceutiques aérosols correspondantes

Family Applications After (1)

Application Number Title Priority Date Filing Date
MA045167A MA45167A (fr) 2016-05-31 2017-05-31 Peptidomimétique en épingle à cheveux bêta présentant une activité d'inhibition de l'élastase et formes pharmaceutiques aérosols correspondantes

Country Status (26)

Country Link
US (3) US11235023B2 (fr)
EP (2) EP3463281B1 (fr)
JP (4) JP7286319B6 (fr)
KR (2) KR102511284B1 (fr)
CN (3) CN109310613A (fr)
AU (2) AU2017273508B2 (fr)
BR (2) BR112018074532B1 (fr)
CA (2) CA3024522A1 (fr)
CL (2) CL2018003391A1 (fr)
DK (2) DK3463281T3 (fr)
EA (2) EA039603B1 (fr)
ES (2) ES2928050T3 (fr)
HR (2) HRP20221185T1 (fr)
HU (2) HUE060393T2 (fr)
IL (2) IL263112B2 (fr)
LT (2) LT3463280T (fr)
MA (2) MA45168A (fr)
MX (2) MX2018014752A (fr)
PH (2) PH12018502522A1 (fr)
PL (2) PL3463281T3 (fr)
PT (2) PT3463281T (fr)
RS (2) RS63622B1 (fr)
SG (3) SG11201810137UA (fr)
UA (2) UA125899C2 (fr)
WO (2) WO2017207118A1 (fr)
ZA (2) ZA201807772B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE060393T2 (hu) * 2016-05-31 2023-02-28 Spexis Ag Béta-hairpin peptidomimetikum elasztáz gátló hatással és annak aeroszolos adagolási formái
BR112022014861A2 (pt) * 2020-01-30 2022-09-20 Vertex Pharma Métodos de tratamento para deficiência de alfa-1 antittripsina
MX2023005982A (es) * 2020-11-23 2023-08-15 Spexis Ag Composiciones de un peptidomimetico de horquilla beta y formas de dosificacion en aerosol del mismo.

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69718047T2 (de) * 1996-11-01 2003-11-13 Xoma Technology Ltd Therapeutische verwendung von bpi proteineprodukten bei patienten mit zystischer fibrose
AU2006206272A1 (en) * 2005-01-21 2006-07-27 Alza Corporation Therapeutic peptide formulations for coating microneedles with improved stabitity containing at least one counterion
KR101420198B1 (ko) * 2005-02-17 2014-08-13 폴리포 리미티드 프로테아제 저해 활성을 가지는 주형-고정된 β-헤어핀 구조의 펩티드모방체
EP1712220A1 (fr) * 2005-04-15 2006-10-18 PARI GmbH Spezialisten für effektive Inhalation Composition d'aérosol pharmaceutique
DK1981572T3 (da) 2006-02-09 2013-03-04 Pari Pharma Gmbh Pulmonal afgivelse af alfa-1-proteinaseinhibitor
LT1991201T (lt) * 2006-02-10 2018-07-25 Pari Pharma Gmbh Puškiami antibiotikai inhaliaciniam gydymui
WO2008025560A1 (fr) 2006-09-01 2008-03-06 Pari Pharma Gmbh Procédés servant à masquer le goût de compositions nébulisées pour thérapie par inhalation nasale et pulmonaire
EP1927373B1 (fr) * 2006-11-30 2012-08-22 PARI Pharma GmbH Nebuliseur d'inhalation
ES2532667T3 (es) 2011-09-12 2015-03-30 Meiji Seika Pharma Co., Ltd. Composiciones acuosas que contienen arbekacina
WO2015096672A1 (fr) 2013-12-23 2015-07-02 石家庄铁道大学 Dispositif de détection
JP6431486B2 (ja) 2013-12-26 2018-11-28 株式会社カネカ 太陽電池のi‐v測定方法、太陽電池のi‐v測定装置、太陽電池の製造方法、太陽電池モジュールの製造方法、および太陽電池モジュール
SI3087094T1 (sl) * 2013-12-27 2022-11-30 Spexis Ag BETA-lasnični peptidomimetiki kot selektivni zaviralci elastaze
EA034910B1 (ru) 2013-12-27 2020-04-06 Полифор Аг Бета-шпилечные пептидомиметики в качестве селективных ингибиторов эластазы
HUE060393T2 (hu) * 2016-05-31 2023-02-28 Spexis Ag Béta-hairpin peptidomimetikum elasztáz gátló hatással és annak aeroszolos adagolási formái

Also Published As

Publication number Publication date
KR20190015309A (ko) 2019-02-13
US11235023B2 (en) 2022-02-01
RS63639B1 (sr) 2022-10-31
EA201892819A1 (ru) 2019-05-31
BR112018074532A2 (pt) 2019-03-19
LT3463281T (lt) 2022-09-26
US11235024B2 (en) 2022-02-01
UA125900C2 (uk) 2022-07-06
EP3463280B1 (fr) 2022-07-06
EA039603B1 (ru) 2022-02-16
EP3463281B1 (fr) 2022-07-06
HRP20221185T1 (hr) 2022-12-09
CN109310613A (zh) 2019-02-05
CA3024521C (fr) 2023-06-20
US11844823B2 (en) 2023-12-19
JP2023017793A (ja) 2023-02-07
CL2018003390A1 (es) 2019-05-03
IL263114A (en) 2018-12-31
KR102511284B1 (ko) 2023-03-16
MX2018014425A (es) 2019-03-28
PH12018502521A1 (en) 2019-10-21
US20200230203A1 (en) 2020-07-23
HUE060119T2 (hu) 2023-02-28
CL2018003391A1 (es) 2019-05-03
MX2018014752A (es) 2019-04-25
SG10202113280XA (en) 2021-12-30
CA3024522A1 (fr) 2017-12-07
SG11201810137UA (en) 2018-12-28
UA125899C2 (uk) 2022-07-06
MA45167A (fr) 2019-04-10
EA201892818A1 (ru) 2019-05-31
HRP20221194T1 (hr) 2022-12-09
AU2017273507A1 (en) 2018-12-13
EP3463281A1 (fr) 2019-04-10
KR20190011750A (ko) 2019-02-07
WO2017207118A1 (fr) 2017-12-07
BR112018074532B1 (pt) 2022-02-08
RS63622B1 (sr) 2022-10-31
CN116159024A (zh) 2023-05-26
DK3463280T3 (da) 2022-09-26
JP2019523763A (ja) 2019-08-29
AU2017273507B2 (en) 2022-03-17
US20200230202A1 (en) 2020-07-23
WO2017207117A1 (fr) 2017-12-07
PL3463280T3 (pl) 2022-11-07
JP7286319B6 (ja) 2023-06-16
HUE060393T2 (hu) 2023-02-28
IL263114B2 (en) 2023-12-01
EP3463280A1 (fr) 2019-04-10
PT3463280T (pt) 2022-10-07
PT3463281T (pt) 2022-10-07
JP7286319B2 (ja) 2023-06-05
CA3024521A1 (fr) 2017-12-07
ES2927948T3 (es) 2022-11-14
AU2017273508B2 (en) 2022-07-28
IL263112B1 (en) 2023-06-01
SG11201810138XA (en) 2018-12-28
IL263114B1 (en) 2023-08-01
BR112018074551A2 (pt) 2019-03-06
IL263112A (en) 2018-12-31
PH12018502522A1 (en) 2019-10-21
JP2022078013A (ja) 2022-05-24
LT3463280T (lt) 2022-09-26
ZA201807772B (en) 2022-10-26
US20220023379A1 (en) 2022-01-27
AU2017273508A1 (en) 2018-12-13
CN109195580A (zh) 2019-01-11
KR102480800B1 (ko) 2022-12-22
BR112018074551B1 (pt) 2022-02-08
PL3463281T3 (pl) 2022-11-07
ES2928050T3 (es) 2022-11-15
DK3463281T3 (da) 2022-09-26
IL263112B2 (en) 2023-10-01
JP2019523222A (ja) 2019-08-22
ZA201807773B (en) 2022-07-27

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