SG10201709400VA - Abiraterone acetate formulation - Google Patents

Abiraterone acetate formulation

Info

Publication number
SG10201709400VA
SG10201709400VA SG10201709400VA SG10201709400VA SG10201709400VA SG 10201709400V A SG10201709400V A SG 10201709400VA SG 10201709400V A SG10201709400V A SG 10201709400VA SG 10201709400V A SG10201709400V A SG 10201709400VA SG 10201709400V A SG10201709400V A SG 10201709400VA
Authority
SG
Singapore
Prior art keywords
abiraterone acetate
acetate formulation
formulation
abiraterone
acetate
Prior art date
Application number
SG10201709400VA
Other languages
English (en)
Inventor
H William Bosch
Marck Norret
Paul Nemeth
Matt Callahan
Original Assignee
Iceutica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iceutica Inc filed Critical Iceutica Inc
Publication of SG10201709400VA publication Critical patent/SG10201709400VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5123Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28Antiandrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00Other disintegrating devices or methods
    • B02C19/16Mills provided with vibrators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG10201709400VA 2013-03-15 2014-03-17 Abiraterone acetate formulation SG10201709400VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361789141P 2013-03-15 2013-03-15
US201361883941P 2013-09-27 2013-09-27

Publications (1)

Publication Number Publication Date
SG10201709400VA true SG10201709400VA (en) 2018-01-30

Family

ID=51538105

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201709400VA SG10201709400VA (en) 2013-03-15 2014-03-17 Abiraterone acetate formulation
SG11201507681PA SG11201507681PA (en) 2013-03-15 2014-03-17 Abiraterone acetate formulation

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201507681PA SG11201507681PA (en) 2013-03-15 2014-03-17 Abiraterone acetate formulation

Country Status (20)

Country Link
US (3) US20140287039A1 (fr)
EP (2) EP2969227B1 (fr)
JP (4) JP2016514707A (fr)
KR (3) KR102121404B1 (fr)
CN (2) CN110604721B (fr)
AU (2) AU2014232508C1 (fr)
BR (1) BR112015023629A8 (fr)
CA (1) CA2907415C (fr)
CL (1) CL2015002787A1 (fr)
ES (1) ES2741800T3 (fr)
HK (2) HK1219457A1 (fr)
IL (1) IL241612B (fr)
MX (1) MX2015013247A (fr)
NZ (1) NZ712350A (fr)
PL (1) PL2969227T3 (fr)
RU (1) RU2732136C2 (fr)
SG (2) SG10201709400VA (fr)
TW (2) TWI686212B (fr)
WO (1) WO2014145813A1 (fr)
ZA (1) ZA201507209B (fr)

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US20150157646A1 (en) 2013-09-27 2015-06-11 Iceutica Inc. Abiraterone Steroid Formulation
EP3080141A1 (fr) * 2013-12-12 2016-10-19 Basf Se Forme solide d'acétate d'abiratérone
WO2015114314A1 (fr) * 2014-01-28 2015-08-06 Cipla Limited Composition pharmaceutique contenant de l'abiratérone
WO2016044701A1 (fr) * 2014-09-18 2016-03-24 Iceutica Inc. Formulation d'acétate d'abiratérone et ses procédés d'utilisation
CN105616364B (zh) * 2014-11-07 2018-11-02 深圳万乐药业有限公司 醋酸阿比特龙片及其制备方法
DK3226843T3 (da) 2014-12-05 2021-08-16 Aragon Pharmaceuticals Inc Anticancersammensætninger
HUP1500055A1 (hu) 2015-02-09 2016-08-29 Druggability Technologies Ip Holdco Ltd Abirateron acetát komplexei, eljárás elõállításukra, és az azokat tartalmazó gyógyászati készítmények
WO2016162229A1 (fr) * 2015-04-10 2016-10-13 Capsugel Belgium N.V. Formulations lipidiques d'acétate d'abiratérone
CN108697700B (zh) 2016-02-04 2021-08-17 辛多美制药有限公司 氘代多潘立酮组合物和用于治疗病症的方法
MX2018009866A (es) 2016-02-16 2018-11-09 Gx Tech Canada Ltd Depresor de aleta sustentadora de cinta.
SG11201809680QA (en) * 2016-06-03 2018-11-29 Aragon Pharmaceuticals Inc Anticancer compositions
US11311493B2 (en) * 2017-04-07 2022-04-26 Maa Laboratories, Inc. Methods of improving the solubility and bioavailability of therapeutic agents
US11364226B2 (en) 2017-06-30 2022-06-21 Cinrx Pharma, Llc Deuterated domperidone compositions, methods, and preparation
WO2019060525A1 (fr) * 2017-09-22 2019-03-28 Dispersol Technologies, Llc Formulations pharmaceutiques d'oligomère cyclique et d'abiratérone et procédés de formation et d'administration de celles-ci
US20210008081A1 (en) * 2018-03-29 2021-01-14 Leiutis Pharmaceuticals Pvt, Ltd Oral liquid formulations of abiraterone
WO2020023017A1 (fr) * 2018-07-24 2020-01-30 Camx Power, L.L.C. Additif et procédé de broyage à sec
JP2021533194A (ja) 2018-07-31 2021-12-02 マイクロビオン コーポレーション ビスマス・チオール組成物及び創傷を治療する方法
HU231297B1 (hu) * 2018-07-31 2022-09-28 Richter Gedeon Nyrt Stabil gyógyszerkészítmények és eljárás az előállításukra
EP3863918A4 (fr) 2018-10-09 2022-07-20 GX Technology Canada Ltd. Système de foils modulaire pour réseau marin remorqué
EP3914234A4 (fr) * 2019-01-25 2022-09-14 Shenzhen Pharmacin Co., Ltd. Compositions pharmaceutiques
US10792292B2 (en) 2019-03-06 2020-10-06 Propella Therapeutics, Inc. Abiraterone prodrugs
CN113133983B (zh) * 2020-01-20 2023-12-12 鲁南制药集团股份有限公司 一种治疗前列腺癌的药物组合物
EP3944860A1 (fr) 2020-07-30 2022-02-02 Galenicum Health S.L.U. Abiratérone pour utilisation dans un procédé de traitement du cancer
CN112933053B (zh) * 2021-01-29 2022-11-25 中国药科大学 一种醋酸阿比特龙的纳米晶体及其制剂和制备方法
CN117120034A (zh) 2021-02-15 2023-11-24 普洛佩拉治疗公司 阿比特龙前药
US11801252B2 (en) * 2021-03-05 2023-10-31 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Pharmaceutical composition
EP4197541A1 (fr) 2021-12-15 2023-06-21 Hunan Huize Biopharma S&T Co., Ltd Composition contenant de l'acétate d'abiratérone et son application
KR20240010280A (ko) 2022-07-15 2024-01-23 한미약품 주식회사 아비라테론 아세테이트 또는 이의 약제학적으로 허용 가능한 염을 포함하는 약제학적 조성물

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Also Published As

Publication number Publication date
JP2023103410A (ja) 2023-07-26
ZA201507209B (en) 2016-12-21
CA2907415C (fr) 2022-04-05
BR112015023629A2 (pt) 2017-07-18
KR20180021932A (ko) 2018-03-05
CN105246598B (zh) 2019-09-13
TW201943408A (zh) 2019-11-16
AU2014232508A1 (en) 2015-10-08
JP2021008521A (ja) 2021-01-28
KR20160023641A (ko) 2016-03-03
KR20190141270A (ko) 2019-12-23
JP2016514707A (ja) 2016-05-23
US20170354665A1 (en) 2017-12-14
TWI686212B (zh) 2020-03-01
IL241612B (en) 2020-03-31
RU2732136C2 (ru) 2020-09-11
CA2907415A1 (fr) 2014-09-18
AU2014232508B2 (en) 2018-07-12
AU2014232508C1 (en) 2023-01-19
HK1220162A1 (zh) 2017-04-28
HK1219457A1 (zh) 2017-04-07
US20140287039A1 (en) 2014-09-25
SG11201507681PA (en) 2015-10-29
NZ712350A (en) 2020-08-28
EP2969227B1 (fr) 2019-05-08
RU2015144285A (ru) 2017-04-24
JP2018135351A (ja) 2018-08-30
ES2741800T3 (es) 2020-02-12
MX2015013247A (es) 2016-11-25
CN110604721A (zh) 2019-12-24
JP7320485B2 (ja) 2023-08-03
BR112015023629A8 (pt) 2023-04-11
TW201513896A (zh) 2015-04-16
EP3578266B1 (fr) 2024-06-19
AU2018241103B2 (en) 2020-08-13
WO2014145813A1 (fr) 2014-09-18
EP3578266A1 (fr) 2019-12-11
US20160067265A1 (en) 2016-03-10
TWI731321B (zh) 2021-06-21
CN105246598A (zh) 2016-01-13
EP2969227A4 (fr) 2016-12-07
CN110604721B (zh) 2022-02-08
KR102121404B1 (ko) 2020-06-11
EP2969227A1 (fr) 2016-01-20
PL2969227T3 (pl) 2019-12-31
AU2018241103A1 (en) 2018-10-25
CL2015002787A1 (es) 2016-05-13

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