SG10201704665QA - Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof - Google Patents

Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof

Info

Publication number
SG10201704665QA
SG10201704665QA SG10201704665QA SG10201704665QA SG10201704665QA SG 10201704665Q A SG10201704665Q A SG 10201704665QA SG 10201704665Q A SG10201704665Q A SG 10201704665QA SG 10201704665Q A SG10201704665Q A SG 10201704665QA SG 10201704665Q A SG10201704665Q A SG 10201704665QA
Authority
SG
Singapore
Prior art keywords
methods
benzimidazole derivatives
parasiticidal compositions
parasiticidal
compositions
Prior art date
Application number
SG10201704665QA
Other languages
English (en)
Inventor
Charles Q Meng
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc filed Critical Merial Inc
Publication of SG10201704665QA publication Critical patent/SG10201704665QA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG10201704665QA 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof SG10201704665QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261635961P 2012-04-20 2012-04-20

Publications (1)

Publication Number Publication Date
SG10201704665QA true SG10201704665QA (en) 2017-07-28

Family

ID=48225136

Family Applications (3)

Application Number Title Priority Date Filing Date
SG11201406730RA SG11201406730RA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
SG10201700291VA SG10201700291VA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
SG10201704665QA SG10201704665QA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SG11201406730RA SG11201406730RA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
SG10201700291VA SG10201700291VA (en) 2012-04-20 2013-04-18 Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof

Country Status (24)

Country Link
US (3) US9000187B2 (es)
EP (3) EP3763706A1 (es)
JP (4) JP6161173B2 (es)
KR (3) KR102160836B1 (es)
CN (4) CN107353254A (es)
AR (1) AR090766A1 (es)
AU (2) AU2013249217B2 (es)
BR (3) BR112014026184B1 (es)
CA (2) CA2870956C (es)
CL (3) CL2014002831A1 (es)
CO (1) CO7151497A2 (es)
EA (1) EA028430B1 (es)
ES (1) ES2703535T3 (es)
HK (1) HK1211580A1 (es)
IL (3) IL235107A (es)
MX (3) MX351636B (es)
NZ (3) NZ711847A (es)
PH (1) PH12014502345A1 (es)
PT (1) PT2895465T (es)
SG (3) SG11201406730RA (es)
UA (1) UA115981C2 (es)
UY (1) UY34761A (es)
WO (1) WO2013158894A1 (es)
ZA (1) ZA201407605B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106536481B (zh) 2014-06-19 2019-11-22 勃林格殷格翰动物保健美国公司 包含吲哚衍生物的杀寄生物的组合物、其用法和用途
US10342219B2 (en) 2016-03-31 2019-07-09 Boehringer Ingelheim Animal Health USA Inc. Single or dual technology animal tags and system and method of using the same
CN106496037A (zh) * 2016-10-20 2017-03-15 上海毕得医药科技有限公司 一种1,4‑二碘‑2‑甲氧基‑5‑硝基苯的合成方法
KR102147235B1 (ko) * 2018-05-18 2020-08-24 연세대학교 산학협력단 발광성, 강유전성 및 압전성을 나타내는 헤테로아릴 화합물 및 이를 포함하는 전자소자
GB201811695D0 (en) 2018-07-17 2018-08-29 Salvensis Compounds for use in the treatment of fascioliasis
WO2024026359A1 (en) * 2022-07-26 2024-02-01 The Board Of Trustees Of The University Of Illinois Compounds and methods for the treatment of diseases associated with parasitic worms

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB955961A (en) * 1959-09-24 1964-04-22 Gevaert Photo Prod Nv Benzimidazole derivatives
NL277327A (es) * 1961-04-24
IL22272A (en) * 1963-11-06 1969-02-27 Merck & Co Inc 2-heteroaryl-5(or 6)-aryl substituted benzazoles
US3578675A (en) * 1969-06-09 1971-05-11 Merck & Co Inc 2-(3'-fluoro-2'-naphthyl)-benzimidazoles
US3749789A (en) * 1970-02-27 1973-07-31 Merck & Co Inc Anthelmintic compositions containing benzimidazoles and method of use
DE2016622A1 (en) * 1970-04-08 1971-10-21 Farbenfabriken Bayer Ag, 5090 Leverkusen Anthelmintic benzimidazole deriv
NL160809C (nl) 1970-05-15 1979-12-17 Duphar Int Res Werkwijze ter bereiding van benzoylureumverbindingen, alsmede werkwijze ter bereiding van insekticide prepara- ten op basis van benzoylureumverbindingen.
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
JPS4914624A (es) 1972-06-08 1974-02-08
US3818047A (en) 1972-08-07 1974-06-18 C Henrick Substituted pyrones
US3815047A (en) 1973-02-14 1974-06-04 Bell Telephone Labor Inc Transversely-excited waveguide gas laser
US4336262A (en) 1973-02-23 1982-06-22 Fisons Ltd. Pour-on veterinary anthelmintic
DK645374A (es) * 1974-01-22 1975-09-29 Ciba Geigy Ag
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
CH604517A5 (es) 1976-08-19 1978-09-15 Ciba Geigy Ag
US4134973A (en) 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
CH634307A5 (de) 1977-04-12 1983-01-31 Ciba Geigy Ag Anthelmintisch wirkende benzimidazolderivate, verfahren zu ihrer herstellung und mittel enthaltend diese wirkstoffe.
CH634306A5 (de) * 1977-04-12 1983-01-31 Ciba Geigy Ag Benzimidazolderivate, verfahren zu ihrer herstellung und anthelmintische mittel enthaltend diese verbindungen als wirkstoffe.
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4144352A (en) 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
US4203976A (en) 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
DE2840927A1 (de) * 1978-09-20 1980-04-10 Bayer Ag 3,4-dihydroisochinoline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
CH642359A5 (en) * 1978-10-02 1984-04-13 Ciba Geigy Ag Benzimidazole derivatives
JPS57139012A (en) 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
JPS59199673A (ja) 1983-04-25 1984-11-12 Sumitomo Chem Co Ltd 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤
DE3580444D1 (en) 1984-10-18 1990-12-13 Ciba Geigy Ag Benzoylphenylharnstoffe.
EP0192060B1 (de) 1985-02-04 1991-09-18 Nihon Bayer Agrochem K.K. Heterocyclische Verbindungen
EP0237482A1 (de) 1986-03-06 1987-09-16 Ciba-Geigy Ag C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen
DE3767560D1 (de) 1986-03-25 1991-02-28 Sankyo Co Makrolide verbindungen, ihre herstellung und verwendung.
EP0252879B1 (de) 1986-07-02 1992-05-06 Ciba-Geigy Ag Pestizide
US4855317A (en) 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4871719A (en) 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
US4874749A (en) 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
JPS6435773A (en) 1987-07-31 1989-02-06 Nippon Denki Home Electronics Signal frequency discriminating device
DE3888936T2 (de) 1987-11-03 1994-07-21 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.
JP2695419B2 (ja) * 1987-11-20 1997-12-24 工業技術院長 ２−（ポリフルオロアルキル）ハロゲノベンズイミダゾール類、その製造法およびそれを有効成分とする殺虫、殺ダニ剤
NZ232422A (en) 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
NZ232785A (en) * 1989-03-15 1991-03-26 Janssen Pharmaceutica Nv 5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions
IE904606A1 (en) 1989-12-21 1991-07-03 Beecham Group Plc Novel products
NZ247278A (en) 1991-02-12 1995-03-28 Ancare Distributors Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
WO1992022555A1 (en) 1991-06-17 1992-12-23 Beecham Group Plc Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents
US5278181A (en) * 1992-05-12 1994-01-11 Board Of Regents Acting On Behalf Of The University Of Michigan Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate anthelmintics
US5345377A (en) 1992-10-30 1994-09-06 Electric Power Research Institute, Inc. Harmonic controller for an active power line conditioner
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
US5399582A (en) 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
AUPM969994A0 (en) 1994-11-28 1994-12-22 Virbac S.A. Equine anthelmintic formulations
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
US5962499A (en) 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
TW334436B (en) 1995-07-21 1998-06-21 Upjohn Co Antiparasitic marcfortines and paraherquamides
IE80657B1 (en) 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
US6207647B1 (en) 1997-07-18 2001-03-27 Smithkline Beecham Corporation RatA
JPH1135773A (ja) * 1997-07-23 1999-02-09 Nippon Synthetic Chem Ind Co Ltd:The エチレン−酢酸ビニル系共重合体ケン化物組成物及び その成形物
PE20011289A1 (es) 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
US6399786B1 (en) 2000-07-14 2002-06-04 Merck & Co., Inc. Nonacyclic nodulisporic acid derivatives
TW200300140A (en) * 2001-11-14 2003-05-16 Novartis Ag Organic compounds
AR042420A1 (es) 2002-09-11 2005-06-22 Novartis Ag Benzotriazolil- aminoacetonitril compuestos, proceso para su preparacion, metodo y uso de los mismos en el control de endo- y ecto-parasitos dentro y sobre ganado productor de sangre caliente y animales domesticos y plantas, y en la preparacion de una composicion farmaceutica
US7396819B2 (en) 2003-08-08 2008-07-08 Virbac Corporation Anthelmintic formulations
DK1731512T3 (en) 2004-03-05 2015-01-05 Nissan Chemical Ind Ltd Isoxazoline-substituted benzamide AND INSTRUMENTS FOR COMBATING HARMFUL ORGANISMS
WO2006050148A2 (en) * 2004-10-29 2006-05-11 Teva Pharmaceutical Industries, Ltd. Propargyl trifluoromethoxy aminobenzimidazole derivatives
WO2006088246A1 (ja) * 2005-02-18 2006-08-24 Takeda Pharmaceutical Company Limited Ｇｐｒ３４受容体機能調節剤
BRPI0620668A2 (pt) 2005-12-14 2011-11-22 Du Pont composto da fórmula 1, composição que compreende composto, composição de controle de pragas invertebradas, composição de pulverização, composição de isca, dispositivo de armadilha, métodos de controle de pragas invertebradas, método de controle de baratas, formigas ou cupins e método de proteção de sementes contra pragas invertebradas
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
PL2035390T3 (pl) * 2006-07-05 2016-06-30 Merial Inc Związki będące pochodnymi 1-arylo-5-alkilopirazolu, sposoby ich wytwarzania i zastosowania
JP2009023986A (ja) * 2006-11-08 2009-02-05 Pharma Ip 抗癌剤としてのビアリール誘導体
MX2009010071A (es) 2007-04-10 2009-10-16 Bayer Cropscience Ag Derivados de aril isoxazolina insecticidas.
SI3428148T1 (sl) 2007-05-15 2021-04-30 Boehringer Ingelheim Animal Health USA Inc. Ariloazol-2-il cianoetilamino spojine, postopek njihove izdelave in postopek njihove uporabe
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
HUE037127T2 (hu) 2007-06-27 2018-08-28 Du Pont Állati károkozó irtására szolgáló eljárás
EP2170321B1 (en) 2007-06-29 2013-05-22 Ah Usa 42 Llc Anthelmintic combination
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TW201111358A (en) * 2009-06-18 2011-04-01 Intervet Int Bv Anthelmintic agents and their use

Also Published As

Publication number Publication date
WO2013158894A1 (en) 2013-10-24
JP6161173B2 (ja) 2017-07-12
IL242980A (en) 2017-08-31
EA028430B1 (ru) 2017-11-30
EP3763706A1 (en) 2021-01-13
NZ701185A (en) 2015-08-28
SG10201700291VA (en) 2017-03-30
CN107353254A (zh) 2017-11-17
CL2014002831A1 (es) 2014-12-12
JP6213852B2 (ja) 2017-10-18
KR102114598B1 (ko) 2020-05-25
EP3453702A2 (en) 2019-03-13
UY34761A (es) 2013-11-29
KR20150002853A (ko) 2015-01-07
CN105732511A (zh) 2016-07-06
CL2017001239A1 (es) 2017-12-11
BR112014026184B1 (pt) 2019-04-24
BR122015032741A2 (pt) 2019-08-27
US20150166485A1 (en) 2015-06-18
IL251177A0 (en) 2017-05-29
BR122015032742A2 (pt) 2018-12-11
BR122015032741B1 (pt) 2019-11-26
JP2016106154A (ja) 2016-06-16
KR20200000470A (ko) 2020-01-02
NZ709589A (en) 2015-10-30
UA115981C2 (uk) 2018-01-25
CN104395295A (zh) 2015-03-04
JP6124321B2 (ja) 2017-05-10
EP2895465B1 (en) 2018-10-03
NZ711847A (en) 2015-11-27
JP6246405B2 (ja) 2017-12-13
MX345971B (es) 2017-02-28
PT2895465T (pt) 2019-01-16
EA201401160A1 (ru) 2015-04-30
JP2015516977A (ja) 2015-06-18
IL235107A (en) 2017-09-28
AU2017202719A1 (en) 2017-05-18
CA2870956C (en) 2020-03-31
PH12014502345B1 (en) 2014-12-22
IL251177B (en) 2018-03-29
CN104395295B (zh) 2018-03-06
MX2014012713A (es) 2015-01-19
KR20190114002A (ko) 2019-10-08
CN105884693A (zh) 2016-08-24
CL2018003596A1 (es) 2019-01-25
US20130281392A1 (en) 2013-10-24
EP2895465A1 (en) 2015-07-22
ES2703535T3 (es) 2019-03-11
AU2013249217A1 (en) 2014-11-06
CO7151497A2 (es) 2014-12-29
EP3453702A3 (en) 2019-05-15
CA2870956A1 (en) 2013-10-24
MX367536B (es) 2019-08-26
US9695129B2 (en) 2017-07-04
AU2013249217B2 (en) 2017-04-27
BR122015032742B1 (pt) 2020-04-07
PH12014502345A1 (en) 2014-12-22
BR112014026184A2 (pt) 2017-06-27
MX351636B (es) 2017-10-23
US9000187B2 (en) 2015-04-07
KR102160889B1 (ko) 2020-09-28
JP2016155837A (ja) 2016-09-01
JP2017119716A (ja) 2017-07-06
CN105884693B (zh) 2019-11-01
HK1211580A1 (en) 2016-05-27
CN105732511B (zh) 2018-08-17
ZA201407605B (en) 2015-11-25
US9359305B2 (en) 2016-06-07
US20160251317A1 (en) 2016-09-01
KR102160836B1 (ko) 2020-09-28
CA3059936A1 (en) 2013-10-24
AR090766A1 (es) 2014-12-03
SG11201406730RA (en) 2014-11-27

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