SG10201606540RA - Pens for biological micro-objects - Google Patents
Pens for biological micro-objectsInfo
- Publication number
- SG10201606540RA SG10201606540RA SG10201606540RA SG10201606540RA SG10201606540RA SG 10201606540R A SG10201606540R A SG 10201606540RA SG 10201606540R A SG10201606540R A SG 10201606540RA SG 10201606540R A SG10201606540R A SG 10201606540RA SG 10201606540R A SG10201606540R A SG 10201606540RA
- Authority
- SG
- Singapore
- Prior art keywords
- pens
- objects
- biological micro
- biological
- micro
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/02—Separators
- B03C5/022—Non-uniform field separators
- B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0668—Trapping microscopic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0877—Flow chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0424—Dielectrophoretic forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0454—Moving fluids with specific forces or mechanical means specific forces radiation pressure, optical tweezers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Electrochemistry (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Fluid Mechanics (AREA)
- Clinical Laboratory Science (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261720956P | 2012-10-31 | 2012-10-31 | |
US14/060,117 US9857333B2 (en) | 2012-10-31 | 2013-10-22 | Pens for biological micro-objects |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201606540RA true SG10201606540RA (en) | 2016-09-29 |
Family
ID=50545993
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201600580PA SG11201600580PA (en) | 2012-10-31 | 2013-10-30 | Pens for biological micro-objects |
SG10201606540RA SG10201606540RA (en) | 2012-10-31 | 2013-10-30 | Pens for biological micro-objects |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201600580PA SG11201600580PA (en) | 2012-10-31 | 2013-10-30 | Pens for biological micro-objects |
Country Status (12)
Country | Link |
---|---|
US (4) | US9857333B2 (fr) |
EP (2) | EP3885043A1 (fr) |
JP (3) | JP6529908B2 (fr) |
KR (3) | KR102340691B1 (fr) |
CN (2) | CN108070582B (fr) |
AU (3) | AU2013337937B2 (fr) |
CA (1) | CA2888810C (fr) |
DK (1) | DK2914965T3 (fr) |
HK (3) | HK1249131A1 (fr) |
IL (2) | IL272535B2 (fr) |
SG (2) | SG11201600580PA (fr) |
WO (1) | WO2014070873A1 (fr) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201602629RA (en) * | 2013-10-22 | 2016-05-30 | Berkeley Lights Inc | Microfluidic devices having isolation pens and methods of testing biological micro-objects with same |
CA2925326C (fr) * | 2013-10-22 | 2021-05-25 | Berkeley Lights, Inc. | Dispositifs microfluidiques pour dosage d'activite biologique |
DK3473700T3 (da) * | 2013-10-22 | 2020-07-13 | Berkeley Lights Inc | Mikrofluidanordninger med isoleringsaflukker og fremgangsmåder til test af biologiske mikroobjekter dermed |
US9889445B2 (en) | 2013-10-22 | 2018-02-13 | Berkeley Lights, Inc. | Micro-fluidic devices for assaying biological activity |
US20150166326A1 (en) | 2013-12-18 | 2015-06-18 | Berkeley Lights, Inc. | Capturing Specific Nucleic Acid Materials From Individual Biological Cells In A Micro-Fluidic Device |
US20150306599A1 (en) | 2014-04-25 | 2015-10-29 | Berkeley Lights, Inc. | Providing DEP Manipulation Devices And Controllable Electrowetting Devices In The Same Microfluidic Apparatus |
US11192107B2 (en) | 2014-04-25 | 2021-12-07 | Berkeley Lights, Inc. | DEP force control and electrowetting control in different sections of the same microfluidic apparatus |
US20150306598A1 (en) * | 2014-04-25 | 2015-10-29 | Berkeley Lights, Inc. | DEP Force Control And Electrowetting Control In Different Sections Of The Same Microfluidic Apparatus |
CN107257711B (zh) | 2014-12-05 | 2019-11-22 | 加利福尼亚大学董事会 | 具有集成网状地线的单面光致动微流体器件 |
CN110918142B (zh) | 2014-12-08 | 2022-10-25 | 伯克利之光生命科技公司 | 微流体装置中定向流动的致动微流体结构及使用它的方法 |
TWI721545B (zh) | 2014-12-08 | 2021-03-11 | 美商柏克萊燈光有限公司 | 側向式/垂直式電晶體結構及其製造與使用方法 |
CN107206377B (zh) * | 2014-12-09 | 2020-02-11 | 伯克利之光生命科技公司 | 微流体装置中测定阳性的区域的自动检测 |
CN113075113A (zh) * | 2014-12-09 | 2021-07-06 | 伯克利之光生命科技公司 | 微流体装置中微物体的自动检测和重新定位 |
SG10202102009QA (en) * | 2014-12-10 | 2021-04-29 | Berkeley Lights Inc | Systems for operating electrokinetic devices |
WO2016094715A2 (fr) | 2014-12-10 | 2016-06-16 | Berkeley Lights, Inc. | Déplacement et sélection de micro-objets dans un appareil micro-fluidique |
WO2016141343A1 (fr) * | 2015-03-04 | 2016-09-09 | Berkeley Lights, Inc. | Production et sélection d'embryons in vitro |
EP3270801A4 (fr) * | 2015-03-04 | 2018-12-12 | Berkeley Lights, Inc. | Production et sélection d'embryons in vitro |
CN107810059B (zh) | 2015-04-22 | 2021-03-23 | 伯克利之光生命科技公司 | 在微流体装置上冷冻和存档细胞 |
SG10202100281RA (en) | 2015-04-22 | 2021-02-25 | Berkeley Lights Inc | Microfluidic cell culture |
US10101250B2 (en) | 2015-04-22 | 2018-10-16 | Berkeley Lights, Inc. | Manipulation of cell nuclei in a micro-fluidic device |
US10751715B1 (en) | 2015-04-22 | 2020-08-25 | Berkeley Lights, Inc. | Microfluidic reporter cell assay methods and kits thereof |
CN114085730A (zh) * | 2015-04-22 | 2022-02-25 | 伯克利之光生命科技公司 | 微流体细胞培养 |
SG10202107069UA (en) * | 2015-10-27 | 2021-07-29 | Berkeley Lights Inc | Microfluidic electrowetting device apparatus having a covalently bound hydrophobic surface |
US10799865B2 (en) | 2015-10-27 | 2020-10-13 | Berkeley Lights, Inc. | Microfluidic apparatus having an optimized electrowetting surface and related systems and methods |
KR20180085783A (ko) * | 2015-11-23 | 2018-07-27 | 버클리 라잇츠, 인크. | 인 시츄-생성된 미세유체 격리 구조체들, 키트들, 및 그 이용 방법들 |
US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
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AU2016381833C1 (en) | 2015-12-30 | 2022-10-06 | Berkeley Lights, Inc. | Microfluidic devices for optically-driven convection and displacement, kits and methods thereof |
WO2017117521A1 (fr) | 2015-12-31 | 2017-07-06 | Berkeley Lights, Inc. | Cellules infiltrant les tumeurs, modifiées pour exprimer un polypeptide pro-inflammatoire |
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WO2017160991A1 (fr) | 2016-03-16 | 2017-09-21 | Lavieu Gregory G | Procédés, systèmes et dispositifs pour la sélection et la génération de clones résultant d'une édition génomique |
JP7287782B2 (ja) | 2016-03-17 | 2023-06-06 | バークレー ライツ,インコーポレイテッド | マイクロ流体デバイスにおけるtリンパ球の選択及びクローニング |
KR102451535B1 (ko) | 2016-03-31 | 2022-10-05 | 버클리 라잇츠, 인크. | 핵산 안정화 시약, 키트들, 및 그 이용 방법들 |
US10675625B2 (en) * | 2016-04-15 | 2020-06-09 | Berkeley Lights, Inc | Light sequencing and patterns for dielectrophoretic transport |
CA3020976A1 (fr) | 2016-04-15 | 2017-10-19 | Berkeley Lights, Inc. | Procedes, systemes et kits pour dosages in pen |
WO2017205830A1 (fr) | 2016-05-26 | 2017-11-30 | Berkeley Lights, Inc. | Surfaces modifiées par covalence, kits et procédés de préparation et d'utilisation |
ES2899107T3 (es) * | 2016-06-21 | 2022-03-10 | Quantumdx Group Ltd | Concentración de células diana mejorada mediante dielectroforesis (DEP) |
WO2018018017A1 (fr) | 2016-07-21 | 2018-01-25 | Berkeley Lights, Inc. | Tri de lymphocytes t dans un dispositif microfluidique |
KR102650753B1 (ko) | 2016-10-01 | 2024-03-26 | 버클리 라잇츠, 인크. | 미세유체 장치에서 인 시츄 식별을 위한 dna 바코드 조성물 및 방법 |
JP2019537157A (ja) | 2016-12-01 | 2019-12-19 | バークレー ライツ,インコーポレイテッド | マイクロ流体デバイスによる微小物体の自動検出及び再配置 |
WO2018102747A1 (fr) | 2016-12-01 | 2018-06-07 | Berkeley Lights, Inc. | Appareils, systèmes et méthodes pour l'imagerie de micro-objets |
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WO2019075476A2 (fr) | 2017-10-15 | 2019-04-18 | Berkeley Lights, Inc. | Procédés, systèmes et kits pour essais « en enclos » |
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DE102018203047A1 (de) * | 2018-03-01 | 2019-09-05 | Robert Bosch Gmbh | Mikrofluidische Vorrichtung |
US11041834B2 (en) | 2018-03-06 | 2021-06-22 | Waters Technologies Corporation | High surface area chromatographic device with low pressure drop |
WO2019232473A2 (fr) | 2018-05-31 | 2019-12-05 | Berkeley Lights, Inc. | Détection et caractérisation automatiques de micro-objets dans des dispositifs microfluidiques |
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CA3054046A1 (fr) * | 2018-09-04 | 2020-03-04 | The Governing Council Of The University Of Toronto | Brucelles optoelectroniques a motifs |
WO2020056339A1 (fr) * | 2018-09-14 | 2020-03-19 | Berkeley Lights, Inc. | Procédé pour analyser l'affinité d'une liaison |
TW202027761A (zh) | 2018-09-21 | 2020-08-01 | 美商柏克萊燈光有限公司 | 功能化孔盤、其製備方法及用途 |
AR116719A1 (es) * | 2018-10-10 | 2021-06-09 | Stamm Vegh Corp | Microbiorreactor de flujo continuo |
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CN110618095A (zh) * | 2019-11-08 | 2019-12-27 | 武汉大学深圳研究院 | 一种光流控水体溶解氧探测器 |
KR20220113683A (ko) | 2019-11-17 | 2022-08-16 | 버클리 라잇츠, 인크. | 생물학적 샘플의 분석을 위한 시스템 및 방법 |
EP4100198A4 (fr) | 2020-02-03 | 2024-02-21 | Stamm Vegh Corporation | Plateforme, systèmes et dispositifs pour l'impression en trois dimensions (3d) |
JP2023517583A (ja) * | 2020-03-09 | 2023-04-26 | バークレー ライツ,インコーポレイテッド | ペン内アッセイのための方法、システム及びキット |
US11479779B2 (en) | 2020-07-31 | 2022-10-25 | Zymergen Inc. | Systems and methods for high-throughput automated strain generation for non-sporulating fungi |
WO2023032827A1 (fr) | 2021-08-31 | 2023-03-09 | キヤノン株式会社 | Corps moulé non expansé contenant du polyuréthane |
EP4239333A1 (fr) | 2022-03-03 | 2023-09-06 | Lonza Biologics plc | Procédé de sélection de cellules clonales exprimant des molécules de liaison multispécifiques assemblées correctement |
WO2024076923A1 (fr) * | 2022-10-03 | 2024-04-11 | Bruker Cellular Analysis, Inc. | Déplacement de micro-objet dans un environnement microfluidique |
Family Cites Families (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0907889B1 (fr) | 1996-04-25 | 2007-07-04 | BioArray Solutions Ltd. | Assemblage electrocinetique de particules proches des surfaces regule par la lumiere |
US6294063B1 (en) | 1999-02-12 | 2001-09-25 | Board Of Regents, The University Of Texas System | Method and apparatus for programmable fluidic processing |
US6942776B2 (en) | 1999-05-18 | 2005-09-13 | Silicon Biosystems S.R.L. | Method and apparatus for the manipulation of particles by means of dielectrophoresis |
AU779988B2 (en) | 1999-06-28 | 2005-02-24 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
US20030007894A1 (en) | 2001-04-27 | 2003-01-09 | Genoptix | Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles |
ITTO20010411A1 (it) | 2001-05-02 | 2002-11-02 | Silicon Biosystems S R L | Metodo e dispositivo per l'esecuzione di test e saggi ad alta processivita' ed alto valore biologico su cellule e/o composti. |
US7075162B2 (en) * | 2001-08-30 | 2006-07-11 | Fluidigm Corporation | Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes |
CN1291035C (zh) * | 2001-10-09 | 2006-12-20 | 清华大学 | 用于样品制备和分析的集成式生物芯片系统 |
US7312085B2 (en) | 2002-04-01 | 2007-12-25 | Fluidigm Corporation | Microfluidic particle-analysis systems |
AU2003224817B2 (en) | 2002-04-01 | 2008-11-06 | Fluidigm Corporation | Microfluidic particle-analysis systems |
US6958132B2 (en) | 2002-05-31 | 2005-10-25 | The Regents Of The University Of California | Systems and methods for optical actuation of microfluidics based on opto-electrowetting |
US7790443B2 (en) | 2002-08-27 | 2010-09-07 | Vanderbilt University | Bioreactors with substance injection capacity |
WO2004065618A2 (fr) | 2003-01-16 | 2004-08-05 | Thermogenic Imaging | Procedes et dispositifs permettant de controler le metabolisme cellulaire dans des chambres de retenue de cellules |
EP2340890B1 (fr) | 2003-04-03 | 2016-10-19 | Fluidigm Corporation | Procédé pour réaliser PCR numérique |
WO2004103565A2 (fr) * | 2003-05-19 | 2004-12-02 | Hans-Knöll-Institut für Naturstoff-Forschung e.V. | Dispositif et procede de structuration de liquides et de dosage de liquides de reaction vers des compartiments a liquides noyes dans un fluide de separation |
JP4328168B2 (ja) | 2003-10-02 | 2009-09-09 | ソニー株式会社 | 毛細管現象を利用する物質間の相互作用検出部と該検出部を用いる方法及びバイオアッセイ用基板 |
WO2005072399A2 (fr) | 2004-01-29 | 2005-08-11 | Massachusetts Institute Of Technology | Cytometre permettant le triage a l'echelle microscopique |
WO2005100541A2 (fr) * | 2004-04-12 | 2005-10-27 | The Regents Of The University Of California | Pinces optoelectroniques pour la manipulation de microparticules et de cellules |
US20080257735A1 (en) | 2004-09-24 | 2008-10-23 | Regents Of The University Of California | Microfluidic Device for Enabling the Controlled Growth of Cells and Methods Relating to Same |
US20060091015A1 (en) | 2004-11-01 | 2006-05-04 | Applera Corporation | Surface modification for non-specific adsorption of biological material |
EP1851304A4 (fr) | 2005-02-23 | 2009-10-21 | Cook William A Australia | Dispositif de culture |
EP1904619A4 (fr) | 2005-07-07 | 2012-05-02 | Univ California | Methodes et dispositif pour reseau de culture cellulaire |
AU2006283518A1 (en) | 2005-08-19 | 2007-03-01 | The Regents Of The University Of California | Microfluidic methods for diagnostics and cellular analysis |
CN101548004A (zh) * | 2005-08-19 | 2009-09-30 | 加利福尼亚大学董事会 | 用于诊断学和细胞分析的微流体方法 |
EP1951742A4 (fr) | 2005-10-27 | 2011-06-01 | Life Technologies Corp | Separation optoelectronique de biomolecules |
US8124015B2 (en) | 2006-02-03 | 2012-02-28 | Institute For Systems Biology | Multiplexed, microfluidic molecular assay device and assay method |
US8157434B2 (en) | 2007-01-19 | 2012-04-17 | Fluidigm Corporation | High efficiency and high precision microfluidic devices and methods |
WO2008119066A1 (fr) | 2007-03-28 | 2008-10-02 | The Regents Of The University Of California | Brucelles optoélectroniques à champ latéral simple face et à base de phototransistor |
ATE554859T1 (de) | 2007-05-24 | 2012-05-15 | Univ California | Integrierte fluidische vorrichtungen mit magnetischer sortierung |
EP2078958A1 (fr) | 2007-10-25 | 2009-07-15 | Koninklijke Philips Electronics N.V. | Filtre microfluidique reconfigurable basé sur des champs électriques |
CN103353476B (zh) | 2008-04-03 | 2016-05-25 | 加利福尼亚大学董事会 | 分离并离析细胞、囊泡、纳米颗粒和生物标记的离体多维系统 |
JP2009273459A (ja) | 2008-04-15 | 2009-11-26 | Tosoh Corp | 細胞選別装置、およびそれを用いた細胞選別方法 |
WO2009130694A2 (fr) | 2008-04-21 | 2009-10-29 | Cell Kinetics Ltd. | Supports plats de cellules avec pièges à cellules |
JP5623399B2 (ja) | 2008-07-28 | 2014-11-12 | アギア システムズ エルエルシーAgere Systems LLC | 変量補償浮上量測定システムおよび方法 |
GB2464300A (en) | 2008-10-10 | 2010-04-14 | Univ Dublin City | Microfluidic multiplexed cellular and molecular analysis device and method |
EP2414539B1 (fr) | 2009-04-03 | 2020-12-16 | The Regents of The University of California | Dispositif et procédé pour trier des cellules et d'autres particules biologiques |
US20100273681A1 (en) | 2009-04-27 | 2010-10-28 | Wisconsin Alumni Research Foundation | Combinatorial chemistry reaction cell with optical tweezers |
GB0909923D0 (en) | 2009-06-09 | 2009-07-22 | Oxford Gene Tech Ip Ltd | Picowell capture devices for analysing single cells or other particles |
GB0910330D0 (en) * | 2009-06-16 | 2009-07-29 | Univ Leiden | A biological microfluidics chip and related methods |
JP2011000079A (ja) * | 2009-06-19 | 2011-01-06 | Univ Of Tokyo | 粒子を操作する方法及びマイクロ流体装置 |
CN201834907U (zh) * | 2010-04-15 | 2011-05-18 | 四川国兴盛生物科技有限公司 | 半封闭式围栏 |
WO2011149032A1 (fr) | 2010-05-26 | 2011-12-01 | 東ソー株式会社 | Dispositif de fixation d'échantillon biologique |
CN101947124B (zh) | 2010-06-25 | 2012-07-04 | 博奥生物有限公司 | 一种集成式微流控芯片装置及其使用方法 |
WO2012002515A1 (fr) | 2010-06-30 | 2012-01-05 | 東ソー株式会社 | Structure de fixation de particules et dispositif d'analyse de particules |
US10087408B2 (en) | 2010-07-07 | 2018-10-02 | The University Of British Columbia | System and method for microfluidic cell culture |
US9188593B2 (en) | 2010-07-16 | 2015-11-17 | The University Of British Columbia | Methods for assaying cellular binding interactions |
US9533306B2 (en) | 2010-08-02 | 2017-01-03 | The Regents Of The University Of California | Single sided continuous optoelectrowetting (SCEOW) device for droplet manipulation with light patterns |
JP5804620B2 (ja) * | 2010-08-09 | 2015-11-04 | 一般財団法人生産技術研究奨励会 | 電気的機能を持つマイクロチャンバーアレイ装置およびそれを用いた検査対象物解析方法 |
AU2011302302B2 (en) | 2010-09-14 | 2014-12-11 | The Regents Of The University Of California | Method and device for isolating cells from heterogeneous solution using microfluidic trapping vortices |
EP2646798B1 (fr) | 2010-12-03 | 2017-06-28 | Cellply S.R.L. | Microanalyse d'une fonction cellulaire |
WO2012072823A1 (fr) | 2010-12-03 | 2012-06-07 | Mindseeds Laboratories Srl | Criblage rapide d'anticorps monoclonaux |
CN102580794B (zh) * | 2011-01-13 | 2014-03-19 | 博奥生物有限公司 | 可定位细胞及生物体的微流控芯片及其应用 |
US9227200B2 (en) | 2011-06-03 | 2016-01-05 | The Regents Of The University Of California | Microfluidic devices with flexible optically transparent electrodes |
CA2842359A1 (fr) | 2011-08-01 | 2013-02-07 | Denovo Sciences | Systeme de capture de cellules et procede d'utilisation |
US10626435B2 (en) | 2012-03-28 | 2020-04-21 | Northeastern University | Nanofluidic device for isolating, growing, and characterizing microbial cells |
CN109342710A (zh) | 2013-03-28 | 2019-02-15 | 英属哥伦比亚大学 | 微流控装置及其在多细胞分泌检测中的使用方法 |
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