SG10201606540RA - Pens for biological micro-objects - Google Patents
Pens for biological micro-objectsInfo
- Publication number
- SG10201606540RA SG10201606540RA SG10201606540RA SG10201606540RA SG10201606540RA SG 10201606540R A SG10201606540R A SG 10201606540RA SG 10201606540R A SG10201606540R A SG 10201606540RA SG 10201606540R A SG10201606540R A SG 10201606540RA SG 10201606540R A SG10201606540R A SG 10201606540RA
- Authority
- SG
- Singapore
- Prior art keywords
- pens
- objects
- biological micro
- biological
- micro
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44791—Microapparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C5/00—Separating dispersed particles from liquids by electrostatic effect
- B03C5/02—Separators
- B03C5/022—Non-uniform field separators
- B03C5/026—Non-uniform field separators using open-gradient differential dielectric separation, i.e. using electrodes of special shapes for non-uniform field creation, e.g. Fluid Integrated Circuit [FIC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0668—Trapping microscopic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0877—Flow chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0424—Dielectrophoretic forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0454—Moving fluids with specific forces or mechanical means specific forces radiation pressure, optical tweezers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Electrochemistry (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Fluid Mechanics (AREA)
- Clinical Laboratory Science (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261720956P | 2012-10-31 | 2012-10-31 | |
US14/060,117 US9857333B2 (en) | 2012-10-31 | 2013-10-22 | Pens for biological micro-objects |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201606540RA true SG10201606540RA (en) | 2016-09-29 |
Family
ID=50545993
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201600580PA SG11201600580PA (en) | 2012-10-31 | 2013-10-30 | Pens for biological micro-objects |
SG10201606540RA SG10201606540RA (en) | 2012-10-31 | 2013-10-30 | Pens for biological micro-objects |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201600580PA SG11201600580PA (en) | 2012-10-31 | 2013-10-30 | Pens for biological micro-objects |
Country Status (12)
Country | Link |
---|---|
US (4) | US9857333B2 (fr) |
EP (2) | EP2914965B1 (fr) |
JP (3) | JP6529908B2 (fr) |
KR (3) | KR101998918B1 (fr) |
CN (2) | CN104838273B (fr) |
AU (3) | AU2013337937B2 (fr) |
CA (1) | CA2888810C (fr) |
DK (1) | DK2914965T3 (fr) |
HK (3) | HK1249131A1 (fr) |
IL (2) | IL272535B2 (fr) |
SG (2) | SG11201600580PA (fr) |
WO (1) | WO2014070873A1 (fr) |
Families Citing this family (66)
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US9889445B2 (en) * | 2013-10-22 | 2018-02-13 | Berkeley Lights, Inc. | Micro-fluidic devices for assaying biological activity |
KR102113377B1 (ko) * | 2013-10-22 | 2020-05-21 | 버클리 라잇츠, 인크. | 격리 펜을 갖는 미세유체 소자 및 이를 사용한 생물학적 미세 물체를 시험하는 방법 |
CN110437975B (zh) * | 2013-10-22 | 2023-06-09 | 伯克利之光生命科技公司 | 具有隔离围栏的微流体装置及用它测试生物微目标的方法 |
EP3060912B1 (fr) * | 2013-10-22 | 2020-07-15 | Berkeley Lights, Inc. | Procédé et dispositif microfluidique pour dosage d'activité biologique |
US20150166326A1 (en) | 2013-12-18 | 2015-06-18 | Berkeley Lights, Inc. | Capturing Specific Nucleic Acid Materials From Individual Biological Cells In A Micro-Fluidic Device |
US20150306599A1 (en) | 2014-04-25 | 2015-10-29 | Berkeley Lights, Inc. | Providing DEP Manipulation Devices And Controllable Electrowetting Devices In The Same Microfluidic Apparatus |
US11192107B2 (en) | 2014-04-25 | 2021-12-07 | Berkeley Lights, Inc. | DEP force control and electrowetting control in different sections of the same microfluidic apparatus |
US20150306598A1 (en) * | 2014-04-25 | 2015-10-29 | Berkeley Lights, Inc. | DEP Force Control And Electrowetting Control In Different Sections Of The Same Microfluidic Apparatus |
TWI698282B (zh) | 2014-12-05 | 2020-07-11 | 加州大學董事會 | 基板、微流體元件、移動微流體元件中的液滴之方法以及用於操控微流體元件中的液滴之程序 |
AU2015360849B2 (en) | 2014-12-08 | 2018-10-11 | Berkeley Lights, Inc. | Microfluidic device comprising lateral/vertical transistor structures and process of making and using same |
CN107249742B (zh) | 2014-12-08 | 2019-12-06 | 伯克利之光生命科技公司 | 微流体装置中定向流动的致动微流体结构及使用它的方法 |
EP3919892A1 (fr) * | 2014-12-09 | 2021-12-08 | Berkeley Lights, Inc. | Détection automatique et repositionnement de micro-objets dans des dispositifs microfluidiques |
EP3230718B1 (fr) * | 2014-12-09 | 2022-03-02 | Berkeley Lights, Inc. | Détection automatisée de zones d'analyse positives ou de quantités d'analytes dans des dispositifs microfluidiques |
WO2016094715A2 (fr) | 2014-12-10 | 2016-06-16 | Berkeley Lights, Inc. | Déplacement et sélection de micro-objets dans un appareil micro-fluidique |
JP2018508743A (ja) | 2014-12-10 | 2018-03-29 | バークレー ライツ,インコーポレイテッド | 界面動電装置を作動させるためのシステム |
EP3270801A4 (fr) * | 2015-03-04 | 2018-12-12 | Berkeley Lights, Inc. | Production et sélection d'embryons in vitro |
JP2018512116A (ja) * | 2015-03-04 | 2018-05-17 | バークレー ライツ,インコーポレイテッド | in vitroでの胚の作成及び選択 |
IL284235B (en) | 2015-04-22 | 2022-07-01 | Berkeley Lights Inc | Kits and methods for preparing a microfluidic device for cell culture |
TWI819383B (zh) * | 2015-04-22 | 2023-10-21 | 美商伯克利之光生命科技公司 | 微流體器件及在該微流體器件中培養生物細胞之方法 |
US10101250B2 (en) | 2015-04-22 | 2018-10-16 | Berkeley Lights, Inc. | Manipulation of cell nuclei in a micro-fluidic device |
CN107810059B (zh) * | 2015-04-22 | 2021-03-23 | 伯克利之光生命科技公司 | 在微流体装置上冷冻和存档细胞 |
US10751715B1 (en) | 2015-04-22 | 2020-08-25 | Berkeley Lights, Inc. | Microfluidic reporter cell assay methods and kits thereof |
US10799865B2 (en) | 2015-10-27 | 2020-10-13 | Berkeley Lights, Inc. | Microfluidic apparatus having an optimized electrowetting surface and related systems and methods |
TWI781484B (zh) * | 2015-10-27 | 2022-10-21 | 美商伯克利之光生命科技公司 | 具最佳化電濕潤表面之微流體裝置以及相關系統和方法 |
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CN108698814A (zh) * | 2015-12-30 | 2018-10-23 | 伯克利之光生命科技公司 | 用于光学驱动的对流和移位的微流体设备、试剂盒及其方法 |
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TWI756199B (zh) | 2016-01-15 | 2022-03-01 | 美商伯克利之光生命科技公司 | 製造患者專ㄧ性抗癌治療劑之方法及使用該治療劑之治療方法 |
WO2017160991A1 (fr) | 2016-03-16 | 2017-09-21 | Lavieu Gregory G | Procédés, systèmes et dispositifs pour la sélection et la génération de clones résultant d'une édition génomique |
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KR102421818B1 (ko) | 2016-04-15 | 2022-07-15 | 버클리 라잇츠, 인크. | 펜 내 분석들을 위한 방법들, 시스템들 및 키트들 |
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KR102551430B1 (ko) | 2016-12-01 | 2023-07-05 | 버클리 라잇츠, 인크. | 미세-객체들을 이미징하기 위한 장치들, 시스템들 및 방법들 |
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