SE9904508D0 - New compounds - Google Patents
New compoundsInfo
- Publication number
- SE9904508D0 SE9904508D0 SE9904508A SE9904508A SE9904508D0 SE 9904508 D0 SE9904508 D0 SE 9904508D0 SE 9904508 A SE9904508 A SE 9904508A SE 9904508 A SE9904508 A SE 9904508A SE 9904508 D0 SE9904508 D0 SE 9904508D0
- Authority
- SE
- Sweden
- Prior art keywords
- new compounds
- active compounds
- compounds
- solvates
- stereoisomers
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/48—Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof
- C07F9/4808—Phosphonous acids [RP(OH)2] including [RHP(=O)(OH)]; Thiophosphonous acids including [RP(SH)2], [RHP(=S)(SH)]; Derivatives thereof the acid moiety containing a substituent or structure which is considered as characteristic
- C07F9/4816—Acyclic saturated acids or derivatices which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Nutrition Science (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (42)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9904508A SE9904508D0 (sv) | 1999-12-09 | 1999-12-09 | New compounds |
| UA2002064507A UA71649C2 (en) | 1999-12-09 | 2000-04-12 | Aminopropylphosphinic acids and pharmaceutical composition based thereon |
| TW089125135A TWI228510B (en) | 1999-12-09 | 2000-11-27 | New aminopropylphosphonous acids |
| AU20364/01A AU780459B2 (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphinic acids |
| EP04021533A EP1484333A1 (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphonous acids |
| CA2397583A CA2397583C (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphinic acids |
| RU2002113909/04A RU2260595C2 (ru) | 1999-12-09 | 2000-12-04 | Новые аминопропилфосфиновые кислоты |
| PT00983634T PT1240172E (pt) | 1999-12-09 | 2000-12-04 | Novos acidos aminopropilfosfinicos |
| SI200030561T SI1240172T1 (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphinic acids |
| KR1020027007355A KR100689144B1 (ko) | 1999-12-09 | 2000-12-04 | 신규 아미노프로필포스핀산 |
| EEP200200286A EE05067B1 (et) | 1999-12-09 | 2000-12-04 | Aminoproplfosfiinhapped ning nende kasutamine meditsiinis |
| PL364795A PL201789B1 (pl) | 1999-12-09 | 2000-12-04 | Kwasy aminopropylofosfinowe, ich zastosowanie i środek farmaceutyczny |
| HK03100457.3A HK1048321B (en) | 1999-12-09 | 2000-12-04 | New aminopropyl phosphinic acid |
| MXPA02005536A MXPA02005536A (es) | 1999-12-09 | 2000-12-04 | Acidos aminopropilfosfinicos novedosos. |
| SK764-2002A SK286904B6 (sk) | 1999-12-09 | 2000-12-04 | Aminopropylfosfínové kyseliny, ich použitie a farmaceutické prípravky s ich obsahom |
| HK03105473.2A HK1053125B (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphinic acids |
| ARP000106418A AR030541A1 (es) | 1999-12-09 | 2000-12-04 | Acidos aminopropilfosfinicos, su utilizacion para la manufactura de medicamentos, y formulacion farmaceutica |
| DE60015796T DE60015796T2 (de) | 1999-12-09 | 2000-12-04 | Neue aminopropylphosphinsäuren |
| EP00983634A EP1240172B1 (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphinic acids |
| BR0016253-1A BR0016253A (pt) | 1999-12-09 | 2000-12-04 | Composto, uso de um composto, métodos para a inibição dos relaxamentos do esfìncter esofágico inferior transientes para o tratamento da doença do refluxo gastroesofágico, da regurgitação em bebês, de nocicepção, êmese. dispepsia, ibs, soluções, adicção em cocaìna, dor, tosse, eructação, asma relacionados ou não com gord, formulação farmacêutica, e, processo para a preparação de um composto |
| NZ519376A NZ519376A (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphinic acids |
| CZ20021983A CZ20021983A3 (cs) | 1999-12-09 | 2000-12-04 | Nové aminopropylfosfinové kyseliny |
| CNB008168989A CN1198832C (zh) | 1999-12-09 | 2000-12-04 | 新的氨基丙基次膦酸 |
| JP2001543550A JP3914435B2 (ja) | 1999-12-09 | 2000-12-04 | 新規なアミノプロピルホスフィン酸 |
| ES00983634T ES2230174T3 (es) | 1999-12-09 | 2000-12-04 | Nuevos acidos aminopropilfosfinicos. |
| AT00983634T ATE282043T1 (de) | 1999-12-09 | 2000-12-04 | Neue aminopropylphosphinsäuren |
| HU0300301A HUP0300301A3 (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphinic acids |
| US09/786,219 US6576626B2 (en) | 1999-12-09 | 2000-12-04 | Aminopropylphosphinic acids |
| IL14984000A IL149840A0 (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphinic acids |
| DK00983634T DK1240172T3 (da) | 1999-12-09 | 2000-12-04 | Nye aminopropylphosphinsyrer |
| PCT/SE2000/002426 WO2001042252A1 (en) | 1999-12-09 | 2000-12-04 | New aminopropylphosphinic acids |
| MYPI20005746A MY125414A (en) | 1999-12-09 | 2000-12-07 | Aminopropylphosphinic acids |
| ZA200204127A ZA200204127B (en) | 1999-12-09 | 2002-05-23 | New aminopropylphosphinic acids. |
| IS6408A IS2231B (is) | 1999-12-09 | 2002-06-06 | Nýjar amínóprópýlfosfínsýrur |
| NO20022728A NO329595B1 (no) | 1999-12-09 | 2002-06-07 | Nye aminopropylfosfinsyrer, farmasoytiske formuleringer inneholdende slike, samt mellomprodukter til fremstilling av slike |
| US10/406,838 US6841698B2 (en) | 1999-12-09 | 2003-04-04 | Aminopropylphosphinic acids |
| IL149840A IL149840A (en) | 1999-12-09 | 2004-01-01 | Aminopropylphosphinic acids |
| US11/016,543 US7034176B2 (en) | 1999-12-09 | 2004-12-16 | Aminopropylphosphinic acids |
| US11/300,195 US7319095B2 (en) | 1999-12-09 | 2005-12-13 | Use of GABAB receptor agonists |
| US11/400,021 US7807658B2 (en) | 1999-12-09 | 2006-04-07 | Use of GabaB receptor agonists |
| JP2006175983A JP2006306885A (ja) | 1999-12-09 | 2006-06-27 | 新規なアミノプロピルホスフィン酸 |
| US11/776,648 US20080146836A1 (en) | 1999-12-09 | 2007-07-12 | New Aminopropylphosphinic acids |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9904508A SE9904508D0 (sv) | 1999-12-09 | 1999-12-09 | New compounds |
| SE0003640A SE0003640D0 (sv) | 2000-10-09 | 2000-10-09 | New compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9904508D0 true SE9904508D0 (sv) | 1999-12-09 |
Family
ID=26655259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9904508A SE9904508D0 (sv) | 1999-12-09 | 1999-12-09 | New compounds |
Country Status (33)
| Country | Link |
|---|---|
| US (5) | US6576626B2 (OSRAM) |
| EP (2) | EP1240172B1 (OSRAM) |
| JP (2) | JP3914435B2 (OSRAM) |
| KR (1) | KR100689144B1 (OSRAM) |
| CN (1) | CN1198832C (OSRAM) |
| AR (1) | AR030541A1 (OSRAM) |
| AT (1) | ATE282043T1 (OSRAM) |
| AU (1) | AU780459B2 (OSRAM) |
| BR (1) | BR0016253A (OSRAM) |
| CA (1) | CA2397583C (OSRAM) |
| CZ (1) | CZ20021983A3 (OSRAM) |
| DE (1) | DE60015796T2 (OSRAM) |
| DK (1) | DK1240172T3 (OSRAM) |
| EE (1) | EE05067B1 (OSRAM) |
| ES (1) | ES2230174T3 (OSRAM) |
| HK (1) | HK1048321B (OSRAM) |
| HU (1) | HUP0300301A3 (OSRAM) |
| IL (2) | IL149840A0 (OSRAM) |
| IS (1) | IS2231B (OSRAM) |
| MX (1) | MXPA02005536A (OSRAM) |
| MY (1) | MY125414A (OSRAM) |
| NO (1) | NO329595B1 (OSRAM) |
| NZ (1) | NZ519376A (OSRAM) |
| PL (1) | PL201789B1 (OSRAM) |
| PT (1) | PT1240172E (OSRAM) |
| RU (1) | RU2260595C2 (OSRAM) |
| SE (1) | SE9904508D0 (OSRAM) |
| SI (1) | SI1240172T1 (OSRAM) |
| SK (1) | SK286904B6 (OSRAM) |
| TW (1) | TWI228510B (OSRAM) |
| UA (1) | UA71649C2 (OSRAM) |
| WO (1) | WO2001042252A1 (OSRAM) |
| ZA (1) | ZA200204127B (OSRAM) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9904508D0 (sv) * | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
| US7319095B2 (en) * | 1999-12-09 | 2008-01-15 | Astrazeneca Ab | Use of GABAB receptor agonists |
| US20040063684A1 (en) * | 2001-02-05 | 2004-04-01 | Kamm Michael A. | Treatment of oesophageal motility disorders and gastro-oesophageal reflux disease |
| AR033779A1 (es) * | 2001-06-08 | 2004-01-07 | Astrazeneca Ab | Compuestos utiles en la enfermedad de reflujo |
| SE0201939D0 (sv) * | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | New combination |
| SE0201940D0 (sv) * | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | New combination II |
| SE0401653D0 (sv) | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | New compounds |
| SE0402462D0 (sv) * | 2004-10-08 | 2004-10-08 | Astrazeneca Ab | New process |
| WO2006050471A2 (en) | 2004-11-03 | 2006-05-11 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use |
| WO2006050472A2 (en) * | 2004-11-03 | 2006-05-11 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids |
| US20060160777A1 (en) * | 2004-12-27 | 2006-07-20 | Anders Lehmann | New use of GABAbeta receptor agonists |
| JP2009521430A (ja) | 2005-12-23 | 2009-06-04 | アストラゼネカ・アクチエボラーグ | Gaba−b受容体モジュレーター |
| EP1966154A4 (en) | 2005-12-23 | 2011-01-26 | Astrazeneca Ab | IMIDAZOLE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS |
| US7585996B2 (en) | 2006-09-15 | 2009-09-08 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use |
| ES2373255T3 (es) * | 2007-05-04 | 2012-02-01 | Astrazeneca Ab | Proceso para s�?ntesis de �?cidos alquilfosf�?nicos mediante iniciación de una amina y un aminóxido. |
| JP2010534239A (ja) * | 2007-07-25 | 2010-11-04 | アストラゼネカ・アクチエボラーグ | Nerdの治療のための(3−アミノ−2−フルオロプロピル)ホスフィン酸の使用 |
| WO2009082344A1 (en) * | 2007-12-21 | 2009-07-02 | Astrazeneca Ab | Novel process for making (2r)-(3-amino-2-fluoropropyl)phosphinic acid form a |
| EP2235027A4 (en) * | 2007-12-21 | 2011-06-22 | Astrazeneca Ab | NEW CRYSTALLINE FORM OF (2R) - (3-AMINO-2-FLUOROPROPYL) PHOSPHINIC ACID |
| WO2009082348A1 (en) * | 2007-12-21 | 2009-07-02 | Astrazeneca Ab | Novel crystalline form c of (2r)-(3-amino-2-fluoropropyl)phosphinic acid |
| WO2009145716A1 (en) * | 2008-05-28 | 2009-12-03 | Astrazeneca Ab | New pharmaceutical formulation useful in gerd therapy |
| CN102177164B (zh) | 2008-11-05 | 2015-02-11 | 科莱恩金融(Bvi)有限公司 | 利用烯丙醇/丙烯醛制备二烷基次膦酸、二烷基次膦酸酯和二烷基次膦酸盐的方法,以及它们的用途 |
| EP2352740B1 (de) | 2008-11-07 | 2014-09-24 | Clariant Finance (BVI) Limited | Verfahren zur herstellung von dialkylphosphinsäuren, -estern und -salzen mittels acrylsäurederivaten und ihre verwendung |
| DE102008056341A1 (de) | 2008-11-07 | 2010-05-12 | Clariant International Limited | Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung |
| JP5743219B2 (ja) | 2008-11-11 | 2015-07-01 | クラリアント・ファイナンス・(ビーブイアイ)・リミテッド | アリル化合物を用いる、モノアリル官能性ジアルキルホスフィン酸、それらの塩およびエステルの製造方法およびそれらの使用 |
| DE102008060035A1 (de) | 2008-12-02 | 2010-06-10 | Clariant International Limited | Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung |
| DE102008060535A1 (de) | 2008-12-04 | 2010-06-10 | Clariant International Limited | Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylether und ihre Verwendung |
| DE102008063668A1 (de) | 2008-12-18 | 2010-07-01 | Clariant International Limited | Verfahren zur Herstellung von Alkylphosponsäuren, -estern und -salzen mittels Oxidation von Alkylphosphonigsäuren und ihre Verwendung |
| KR101697948B1 (ko) | 2008-12-18 | 2017-01-19 | 클라리언트 파이넌스 (비브이아이)리미티드 | 아세틸렌을 사용하는 에틸렌디알킬포스핀산, 에틸렌디알킬포스핀산 에스테르 및 에틸렌디알킬포스핀산 염의 제조방법 및 이의 용도 |
| DE102008063642A1 (de) | 2008-12-18 | 2010-06-24 | Clariant International Limited | Verfahren zur Herstellung von monocarboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Alkylenoxiden und ihre Verwendung |
| DE102008063627A1 (de) * | 2008-12-18 | 2010-06-24 | Clariant International Limited | Verfahren zur Herstellung von monohydroxyfunktionalisierten Dialkylphosphinsäuren,-estern und -salzen mittels Ethylenoxid und ihre Verwendung |
| DE102008064003A1 (de) | 2008-12-19 | 2010-06-24 | Clariant International Limited | Verfahren zur Herstellung von mono-funktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung |
| WO2011113904A1 (en) | 2010-03-17 | 2011-09-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration |
| US20120016021A1 (en) | 2010-07-15 | 2012-01-19 | Xenoport, Inc. | Methods of treating fragile x syndrome, down's syndrome, autism and related disorders |
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|---|---|---|---|---|
| CH449046A (de) | 1963-07-09 | 1967-12-31 | Ciba Geigy | Verfahren zur Herstellung neuer Aminosäuren |
| GB8425872D0 (en) * | 1984-10-12 | 1984-11-21 | Ciba Geigy Ag | Chemical compounds |
| WO1987004077A1 (en) | 1986-01-03 | 1987-07-16 | The University Of Melbourne | Gastro-oesophageal reflux composition |
| US4740332A (en) * | 1986-05-12 | 1988-04-26 | E. R. Squibb & Sons, Inc. | Process for preparing phosphonous acids |
| GB8820266D0 (en) * | 1988-08-26 | 1988-09-28 | Smith Kline French Lab | Compounds |
| US5281747A (en) | 1989-05-13 | 1994-01-25 | Ciba-Geigy Corporation | Substituted aminoalkylphosphinic acids |
| GB8911017D0 (en) | 1989-05-13 | 1989-06-28 | Ciba Geigy Ag | Substituted aminoalkylphosphinic acids |
| US5567840A (en) | 1989-05-13 | 1996-10-22 | Ciba-Geigy Corporation | Substituted aminoalkylphosphinic acids |
| US5006560A (en) | 1989-12-20 | 1991-04-09 | Schering Corporation | Use of GABA-B selective agonists as anti-tussive agents |
| IL114631A (en) * | 1990-06-22 | 1998-12-06 | Novartis Ag | Anti-epileptic compositions containing gabab- antagonistic compounds |
| FR2663934B1 (fr) | 1990-06-27 | 1994-06-03 | Adir | Nouveaux derives de l'acide 4 - amino butyrique, leur procede de preparation et les preparations pharmaceutiques qui les contiennent. |
| GB9125615D0 (en) * | 1991-12-02 | 1992-01-29 | Wyeth John & Brother Ltd | Amines |
| AU662404B2 (en) * | 1992-05-08 | 1995-08-31 | Novartis Ag | Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids |
| FR2722192A1 (fr) | 1994-07-06 | 1996-01-12 | Adir | Nouveaux derives de l'acide 4-amino butyrique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| GB9420784D0 (en) | 1994-10-14 | 1994-11-30 | Glaxo Group Ltd | Medicaments |
| SE9603408D0 (sv) | 1996-09-18 | 1996-09-18 | Astra Ab | Medical use |
| SE9904507D0 (sv) * | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
| US7319095B2 (en) * | 1999-12-09 | 2008-01-15 | Astrazeneca Ab | Use of GABAB receptor agonists |
| SE9904508D0 (sv) * | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
-
1999
- 1999-12-09 SE SE9904508A patent/SE9904508D0/xx unknown
-
2000
- 2000-04-12 UA UA2002064507A patent/UA71649C2/uk unknown
- 2000-11-27 TW TW089125135A patent/TWI228510B/zh not_active IP Right Cessation
- 2000-12-04 AT AT00983634T patent/ATE282043T1/de active
- 2000-12-04 JP JP2001543550A patent/JP3914435B2/ja not_active Expired - Fee Related
- 2000-12-04 EE EEP200200286A patent/EE05067B1/xx not_active IP Right Cessation
- 2000-12-04 IL IL14984000A patent/IL149840A0/xx active IP Right Grant
- 2000-12-04 HK HK03100457.3A patent/HK1048321B/en not_active IP Right Cessation
- 2000-12-04 MX MXPA02005536A patent/MXPA02005536A/es active IP Right Grant
- 2000-12-04 NZ NZ519376A patent/NZ519376A/en not_active IP Right Cessation
- 2000-12-04 HU HU0300301A patent/HUP0300301A3/hu unknown
- 2000-12-04 CZ CZ20021983A patent/CZ20021983A3/cs unknown
- 2000-12-04 KR KR1020027007355A patent/KR100689144B1/ko not_active Expired - Fee Related
- 2000-12-04 CA CA2397583A patent/CA2397583C/en not_active Expired - Fee Related
- 2000-12-04 PL PL364795A patent/PL201789B1/pl not_active IP Right Cessation
- 2000-12-04 AU AU20364/01A patent/AU780459B2/en not_active Ceased
- 2000-12-04 DK DK00983634T patent/DK1240172T3/da active
- 2000-12-04 EP EP00983634A patent/EP1240172B1/en not_active Expired - Lifetime
- 2000-12-04 US US09/786,219 patent/US6576626B2/en not_active Expired - Fee Related
- 2000-12-04 PT PT00983634T patent/PT1240172E/pt unknown
- 2000-12-04 ES ES00983634T patent/ES2230174T3/es not_active Expired - Lifetime
- 2000-12-04 DE DE60015796T patent/DE60015796T2/de not_active Expired - Lifetime
- 2000-12-04 SK SK764-2002A patent/SK286904B6/sk not_active IP Right Cessation
- 2000-12-04 CN CNB008168989A patent/CN1198832C/zh not_active Expired - Fee Related
- 2000-12-04 WO PCT/SE2000/002426 patent/WO2001042252A1/en not_active Ceased
- 2000-12-04 AR ARP000106418A patent/AR030541A1/es active IP Right Grant
- 2000-12-04 RU RU2002113909/04A patent/RU2260595C2/ru not_active IP Right Cessation
- 2000-12-04 BR BR0016253-1A patent/BR0016253A/pt not_active IP Right Cessation
- 2000-12-04 EP EP04021533A patent/EP1484333A1/en not_active Withdrawn
- 2000-12-04 SI SI200030561T patent/SI1240172T1/xx unknown
- 2000-12-07 MY MYPI20005746A patent/MY125414A/en unknown
-
2002
- 2002-05-23 ZA ZA200204127A patent/ZA200204127B/xx unknown
- 2002-06-06 IS IS6408A patent/IS2231B/is unknown
- 2002-06-07 NO NO20022728A patent/NO329595B1/no not_active IP Right Cessation
-
2003
- 2003-04-04 US US10/406,838 patent/US6841698B2/en not_active Expired - Fee Related
-
2004
- 2004-01-01 IL IL149840A patent/IL149840A/en not_active IP Right Cessation
- 2004-12-16 US US11/016,543 patent/US7034176B2/en not_active Expired - Fee Related
-
2006
- 2006-04-07 US US11/400,021 patent/US7807658B2/en not_active Expired - Fee Related
- 2006-06-27 JP JP2006175983A patent/JP2006306885A/ja active Pending
-
2007
- 2007-07-12 US US11/776,648 patent/US20080146836A1/en not_active Abandoned
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