SE9802454D0 - Production of peptides - Google Patents
Production of peptidesInfo
- Publication number
- SE9802454D0 SE9802454D0 SE9802454A SE9802454A SE9802454D0 SE 9802454 D0 SE9802454 D0 SE 9802454D0 SE 9802454 A SE9802454 A SE 9802454A SE 9802454 A SE9802454 A SE 9802454A SE 9802454 D0 SE9802454 D0 SE 9802454D0
- Authority
- SE
- Sweden
- Prior art keywords
- recombinant
- production
- peptide
- peptides
- cells
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 102000018997 Growth Hormone Human genes 0.000 abstract 1
- 108010051696 Growth Hormone Proteins 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9802454A SE9802454D0 (sv) | 1998-07-08 | 1998-07-08 | Production of peptides |
AU49496/99A AU755083B2 (en) | 1998-07-08 | 1999-07-05 | Method for the production of recombinant peptides with a low amount of trisulfides |
US09/743,023 US7232894B1 (en) | 1998-07-08 | 1999-07-05 | Method for the production of recombinant peptides with a low amount of trisulfides |
AT99933442T ATE248855T1 (de) | 1998-07-08 | 1999-07-05 | Methoden zur herstellung von rekombinanten peptiden mit einer geringen menge von trisulfiden |
CA2344506A CA2344506C (en) | 1998-07-08 | 1999-07-05 | Method for the production of recombinant peptides with a low amount of trisulfides |
EP99933442A EP1095055B1 (en) | 1998-07-08 | 1999-07-05 | Method for the production of recombinant peptides with a low amount of trisulfides |
ES99933442T ES2207255T3 (es) | 1998-07-08 | 1999-07-05 | Procedimiento para la produccion de peptidos recombinantes con un bajo contenido en trisulfuros. |
NZ509179A NZ509179A (en) | 1998-07-08 | 1999-07-05 | Method for reducing the amount of trisulphides in the production of recombinant peptides using an alkali metal or alkaline earth metal salt |
IL14066899A IL140668A0 (en) | 1998-07-08 | 1999-07-05 | Method for the production of recombinant peptides with a low amount of trisulfides |
DK99933442T DK1095055T3 (da) | 1998-07-08 | 1999-07-05 | Fremgangsmåde til fremstilling af rekombinante peptider med en lav trisulfidmængde |
DE69911024T DE69911024T2 (de) | 1998-07-08 | 1999-07-05 | Methoden zur herstellung von rekombinanten peptiden mit einer geringen menge von trisulfiden |
PCT/SE1999/001222 WO2000002900A1 (en) | 1998-07-08 | 1999-07-05 | Method for the production of recombinant peptides with a low amount of trisulfides |
JP2000559129A JP2002520332A (ja) | 1998-07-08 | 1999-07-05 | 少量のトリスルフィドを有する組換えペプチドの製造法 |
PT99933442T PT1095055E (pt) | 1998-07-08 | 1999-07-05 | Metodo para a producao de peptideos recombinantes com baixo teor de trissulfuretos |
US11/750,692 US20070232792A1 (en) | 1998-07-08 | 2007-05-18 | Method for the Production of Recombinant Peptides with a Low Amount of Trisulfides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9802454A SE9802454D0 (sv) | 1998-07-08 | 1998-07-08 | Production of peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9802454D0 true SE9802454D0 (sv) | 1998-07-08 |
Family
ID=20412012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9802454A SE9802454D0 (sv) | 1998-07-08 | 1998-07-08 | Production of peptides |
Country Status (14)
Country | Link |
---|---|
US (2) | US7232894B1 (sv) |
EP (1) | EP1095055B1 (sv) |
JP (1) | JP2002520332A (sv) |
AT (1) | ATE248855T1 (sv) |
AU (1) | AU755083B2 (sv) |
CA (1) | CA2344506C (sv) |
DE (1) | DE69911024T2 (sv) |
DK (1) | DK1095055T3 (sv) |
ES (1) | ES2207255T3 (sv) |
IL (1) | IL140668A0 (sv) |
NZ (1) | NZ509179A (sv) |
PT (1) | PT1095055E (sv) |
SE (1) | SE9802454D0 (sv) |
WO (1) | WO2000002900A1 (sv) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE443074T1 (de) | 1999-03-02 | 2009-10-15 | Life Technologies Corp | Zubereitungen und methoden zur verwendung in rekombinatorischem klonen von nukleinsäuren |
EP2339003A3 (en) | 1999-06-28 | 2011-10-19 | Genentech, Inc. | Apo-2 ligand substitutional variants |
ZA200501841B (en) * | 2002-08-28 | 2007-06-27 | Pharmacia Corp | Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof |
US20040048315A1 (en) | 2002-08-28 | 2004-03-11 | Pharmacia Corporation | Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof |
DE60330787D1 (de) * | 2002-09-20 | 2010-02-11 | Pharmacia Corp | Verfahren zur verringerung der aggregatmengen des pegylierten proteins |
EP1697534B1 (en) | 2003-12-01 | 2010-06-02 | Life Technologies Corporation | Nucleic acid molecules containing recombination sites and methods of using the same |
DE602005020505D1 (de) | 2004-12-29 | 2010-05-20 | Novo Nordisk Healthcare Ag | Verfahren zur verhinderung der bildung von trisulfidderivaten von polypeptiden |
DK2483289T3 (da) | 2009-10-02 | 2019-06-11 | Biogen Ma Inc | Fremgangsmåder til forebyggelse og fjernelse af trisulfidbindinger |
EP2707383B1 (en) | 2011-05-13 | 2018-04-18 | Biogen MA Inc. | Methods of preventing and removing trisulfide bonds |
SG11201700365TA (en) | 2014-07-24 | 2017-02-27 | Genentech Inc | Methods of conjugating an agent to a thiol moiety in a protein that contains at least one trisulfide bond |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5256546A (en) * | 1983-07-15 | 1993-10-26 | Bio-Technology General Corp. | Bacterial expression of porcine growth hormone |
US4985544A (en) * | 1987-08-04 | 1991-01-15 | Kyowa Hakko Kogyo Co., Ltd. | Process for renaturing fish growth hormone |
DK44593D0 (da) * | 1993-04-20 | 1993-04-20 | Novo Nordisk As | Fremgangsmaade til fremstilling af et polypeptid |
US5663304A (en) * | 1993-08-20 | 1997-09-02 | Genentech, Inc. | Refolding of misfolded insulin-like growth factor-I |
ZA955789B (en) * | 1994-07-15 | 1996-03-11 | Novo Nordisk As | A method of converting a hydrophobic derivative of a polypeptide into the native form |
-
1998
- 1998-07-08 SE SE9802454A patent/SE9802454D0/sv unknown
-
1999
- 1999-07-05 DK DK99933442T patent/DK1095055T3/da active
- 1999-07-05 ES ES99933442T patent/ES2207255T3/es not_active Expired - Lifetime
- 1999-07-05 DE DE69911024T patent/DE69911024T2/de not_active Expired - Lifetime
- 1999-07-05 AT AT99933442T patent/ATE248855T1/de not_active IP Right Cessation
- 1999-07-05 CA CA2344506A patent/CA2344506C/en not_active Expired - Fee Related
- 1999-07-05 US US09/743,023 patent/US7232894B1/en not_active Expired - Fee Related
- 1999-07-05 WO PCT/SE1999/001222 patent/WO2000002900A1/en active IP Right Grant
- 1999-07-05 NZ NZ509179A patent/NZ509179A/xx unknown
- 1999-07-05 JP JP2000559129A patent/JP2002520332A/ja active Pending
- 1999-07-05 AU AU49496/99A patent/AU755083B2/en not_active Ceased
- 1999-07-05 PT PT99933442T patent/PT1095055E/pt unknown
- 1999-07-05 EP EP99933442A patent/EP1095055B1/en not_active Revoked
- 1999-07-05 IL IL14066899A patent/IL140668A0/xx unknown
-
2007
- 2007-05-18 US US11/750,692 patent/US20070232792A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU4949699A (en) | 2000-02-01 |
US20070232792A1 (en) | 2007-10-04 |
NZ509179A (en) | 2003-01-31 |
DK1095055T3 (da) | 2003-12-22 |
PT1095055E (pt) | 2003-12-31 |
US7232894B1 (en) | 2007-06-19 |
ES2207255T3 (es) | 2004-05-16 |
IL140668A0 (en) | 2002-02-10 |
EP1095055A1 (en) | 2001-05-02 |
CA2344506C (en) | 2010-05-11 |
ATE248855T1 (de) | 2003-09-15 |
WO2000002900A1 (en) | 2000-01-20 |
DE69911024T2 (de) | 2004-04-01 |
DE69911024D1 (de) | 2003-10-09 |
EP1095055B1 (en) | 2003-09-03 |
JP2002520332A (ja) | 2002-07-09 |
AU755083B2 (en) | 2002-12-05 |
CA2344506A1 (en) | 2000-01-20 |
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