SE9404080L - Förfarande för framställning av en optiskt ren enantiomer av formoterol - Google Patents

Förfarande för framställning av en optiskt ren enantiomer av formoterol

Info

Publication number
SE9404080L
SE9404080L SE9404080A SE9404080A SE9404080L SE 9404080 L SE9404080 L SE 9404080L SE 9404080 A SE9404080 A SE 9404080A SE 9404080 A SE9404080 A SE 9404080A SE 9404080 L SE9404080 L SE 9404080L
Authority
SE
Sweden
Prior art keywords
formoterol
pct
preparing
optically pure
pure enantiomer
Prior art date
Application number
SE9404080A
Other languages
English (en)
Swedish (sv)
Other versions
SE9404080D0 (sv
Inventor
Eric Francotte
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SE9404080D0 publication Critical patent/SE9404080D0/xx
Publication of SE9404080L publication Critical patent/SE9404080L/

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/42Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/43Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/16Preparation of optical isomers
    • C07C231/20Preparation of optical isomers by separation of optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
SE9404080A 1993-12-28 1994-11-24 Förfarande för framställning av en optiskt ren enantiomer av formoterol SE9404080L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH387593 1993-12-28

Publications (2)

Publication Number Publication Date
SE9404080D0 SE9404080D0 (sv) 1994-11-24
SE9404080L true SE9404080L (sv) 1995-06-29

Family

ID=4265367

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9404080A SE9404080L (sv) 1993-12-28 1994-11-24 Förfarande för framställning av en optiskt ren enantiomer av formoterol

Country Status (19)

Country Link
US (1) US5684199A ( )
EP (1) EP0737182A1 ( )
JP (1) JPH09502736A ( )
AU (1) AU678878B2 ( )
BE (1) BE1008713A3 ( )
CA (1) CA2179057A1 ( )
DE (1) DE4446348A1 ( )
DK (1) DK171231B1 ( )
ES (1) ES2141632B1 ( )
FR (1) FR2714377B1 ( )
GB (1) GB2285257A ( )
IE (1) IE941004A1 ( )
IT (1) IT1274784B ( )
LU (1) LU88570A1 ( )
NL (1) NL9402221A ( )
NZ (1) NZ277797A ( )
PT (1) PT101626B ( )
SE (1) SE9404080L ( )
WO (1) WO1995018094A1 ( )

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0979081A4 (en) * 1997-04-30 2003-05-02 Bridge Pharma Inc COMPOSITION AND METHODS USING EUTOMER
SE9703407D0 (sv) * 1997-09-19 1997-09-19 Astra Ab New use
SE9802073D0 (sv) * 1998-06-11 1998-06-11 Astra Ab New use
GB9928311D0 (en) 1999-11-30 2000-01-26 Novartis Ag Organic compounds
GB0012261D0 (en) * 2000-05-19 2000-07-12 Astrazeneca Ab Novel process
GB0219512D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Inhalation compositions with high drug ratios
US8273331B2 (en) * 2002-08-21 2012-09-25 Norton Healthcare Ltd. Inhalation compositions
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
US20050026884A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20050113318A1 (en) * 2003-07-31 2005-05-26 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20090285900A1 (en) * 2003-07-31 2009-11-19 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a beta-agonist bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
JP2011501204A (ja) * 2007-10-29 2011-01-06 ジェネリクス・(ユーケー)・リミテッド 新規なクロマトグラフィー方法
CN101531602B (zh) * 2008-03-10 2014-08-27 北京德众万全医药科技有限公司 一种hplc法分析分离酒石酸福莫特罗中间体的方法
AU2009253877B2 (en) 2008-06-02 2013-09-12 Cipla Limited Process for the synthesis of arformoterol
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
LT2435025T (lt) 2009-05-29 2016-09-26 Pearl Therapeutics, Inc. Veikliosios medžiagos tiekimas per kvėpavimo takus
CN101921200B (zh) * 2009-06-16 2014-01-15 上海医药工业研究院 一种n-苄基-1-(4-甲氧基苯基)-2-丙胺的制备方法
JP6454323B2 (ja) 2013-03-15 2019-01-16 パール セラピューティクス,インコーポレイテッド 粒子状結晶性材料のコンディショニングのための方法及びシステム
BR112015028964A2 (pt) 2013-05-22 2017-07-25 Pearl Therapeutics Inc composição de suspensão, e, método para tratar uma doença ou um distúrbio pulmonar
AU2020287832A1 (en) * 2019-05-07 2022-02-03 Wen Tan Prevention and treatment of pulmonary inflammation and inflammatory remodeling using R-enantiomer beta-2-agonists for reduced adverse effects
CN110376313B (zh) * 2019-08-20 2022-06-07 广州健康元呼吸药物工程技术有限公司 一种检测富马酸福莫特罗或其相关制剂中杂质的方法
WO2023283438A1 (en) 2021-07-09 2023-01-12 Astrazeneca Pharmaceuticals Lp Compositions, methods and systems for aerosol drug delivery
WO2023119093A1 (en) 2021-12-20 2023-06-29 Astrazeneca Ab Compositions, methods and systems for aerosol drug delivery
CN116165319B (zh) * 2022-05-30 2023-11-17 上海奥科达医药科技股份有限公司 富马酸福莫特罗吸入溶液中非对映异构体的检测方法
CN114924020B (zh) * 2022-05-30 2023-04-14 上海奥科达医药科技股份有限公司 酒石酸阿福特罗吸入溶液中非对映异构体的质量控制方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5209186A (en) * 1984-11-30 1986-06-18 Clare Graeme John Tocodynamometers
US4683341A (en) * 1984-12-19 1987-07-28 Daicel Chemical Industries, Ltd. Optical resolution of oxycyclopentenone
SE9003057D0 (sv) * 1990-09-26 1990-09-26 Astra Ab New process

Also Published As

Publication number Publication date
SE9404080D0 (sv) 1994-11-24
DK144694A (da) 1995-06-29
US5684199A (en) 1997-11-04
IT1274784B (it) 1997-07-24
PT101626B (pt) 1996-11-29
AU1315795A (en) 1995-07-17
GB2285257A (en) 1995-07-05
ITRM940808A0 (it) 1994-12-15
EP0737182A1 (en) 1996-10-16
NZ277797A (en) 1996-11-26
DE4446348A1 (de) 1995-06-29
LU88570A1 (de) 1996-02-01
FR2714377B1 (fr) 1996-09-13
ES2141632A1 (es) 2000-03-16
ES2141632B1 (es) 2000-11-16
GB9425568D0 (en) 1995-02-15
NL9402221A (nl) 1995-07-17
BE1008713A3 (fr) 1996-07-02
WO1995018094A1 (en) 1995-07-06
DK171231B1 (da) 1996-08-05
CA2179057A1 (en) 1995-07-06
IE941004A1 (en) 1995-06-28
PT101626A (pt) 1995-07-06
AU678878B2 (en) 1997-06-12
ITRM940808A1 (it) 1996-06-15
FR2714377A1 (fr) 1995-06-30
JPH09502736A (ja) 1997-03-18

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