SE9203496D0 - New oligopeptides - Google Patents
New oligopeptidesInfo
- Publication number
- SE9203496D0 SE9203496D0 SE9203496A SE9203496A SE9203496D0 SE 9203496 D0 SE9203496 D0 SE 9203496D0 SE 9203496 A SE9203496 A SE 9203496A SE 9203496 A SE9203496 A SE 9203496A SE 9203496 D0 SE9203496 D0 SE 9203496D0
- Authority
- SE
- Sweden
- Prior art keywords
- glu
- gln
- seq
- pct
- group
- Prior art date
Links
- 102000015636 Oligopeptides Human genes 0.000 title 1
- 108010038807 Oligopeptides Proteins 0.000 title 1
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 abstract 4
- 150000001412 amines Chemical class 0.000 abstract 3
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- OGNSCSPNOLGXSM-UHFFFAOYSA-N (+/-)-DABA Natural products NCCC(N)C(O)=O OGNSCSPNOLGXSM-UHFFFAOYSA-N 0.000 abstract 1
- XUJNEKJLAYXESH-UWTATZPHSA-N D-Cysteine Chemical compound SC[C@@H](N)C(O)=O XUJNEKJLAYXESH-UWTATZPHSA-N 0.000 abstract 1
- QNAYBMKLOCPYGJ-UWTATZPHSA-N D-alanine Chemical group C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 abstract 1
- 229930195710 D‐cysteine Natural products 0.000 abstract 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical group NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 1
- OGNSCSPNOLGXSM-VKHMYHEASA-N L-2,4-diaminobutyric acid Chemical compound NCC[C@H](N)C(O)=O OGNSCSPNOLGXSM-VKHMYHEASA-N 0.000 abstract 1
- 235000013878 L-cysteine Nutrition 0.000 abstract 1
- 239000004201 L-cysteine Substances 0.000 abstract 1
- 125000000174 L-prolyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(*)=O 0.000 abstract 1
- 125000000773 L-serino group Chemical group [H]OC(=O)[C@@]([H])(N([H])*)C([H])([H])O[H] 0.000 abstract 1
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 abstract 1
- 101100244562 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) oprD gene Proteins 0.000 abstract 1
- GYDJEQRTZSCIOI-UHFFFAOYSA-N Tranexamic acid Chemical group NCC1CCC(C(O)=O)CC1 GYDJEQRTZSCIOI-UHFFFAOYSA-N 0.000 abstract 1
- 108700023159 delta Opioid Receptors Proteins 0.000 abstract 1
- 102000048124 delta Opioid Receptors Human genes 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 102000051367 mu Opioid Receptors Human genes 0.000 abstract 1
- 229960003104 ornithine Drugs 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 abstract 1
- 108020001612 μ-opioid receptors Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9203496A SE9203496D0 (sv) | 1992-11-20 | 1992-11-20 | New oligopeptides |
| US08/433,401 US5872097A (en) | 1992-11-20 | 1993-11-08 | Oligopeptides with affinity to opioid receptors |
| PT94901120T PT745093E (pt) | 1992-11-20 | 1993-11-18 | Oligopeptidos novos com afinidade para receptores opioides |
| DK94901120T DK0745093T3 (da) | 1992-11-20 | 1993-11-18 | Hidtil ukendte oligopeptoder med affinitet til opioidreceptorer |
| JP51303594A JP3470136B2 (ja) | 1992-11-20 | 1993-11-18 | オピオイド受容体に対する親和力を有するオリゴペプチド |
| ES94901120T ES2171445T3 (es) | 1992-11-20 | 1993-11-18 | Nuevos oligopeptidos con afinidad para receptores opioides. |
| RU95113498A RU2131438C1 (ru) | 1992-11-20 | 1993-11-18 | Линейные или циклические олигопептиды, обладающие сродством к опиатным рецепторам, фармацевтическая композиция |
| NZ258260A NZ258260A (en) | 1992-11-20 | 1993-11-18 | Oligopeptide with opioid receptor affinity |
| EP94901120A EP0745093B1 (en) | 1992-11-20 | 1993-11-18 | New oligopeptides with affinity to opioid receptors |
| PCT/SE1993/000986 WO1994012532A1 (en) | 1992-11-20 | 1993-11-18 | New oligopeptides with affinity to opioid receptors |
| AT94901120T ATE212357T1 (de) | 1992-11-20 | 1993-11-18 | Neue oligopeptide mit affinität für opioidrezeptoren |
| AU55816/94A AU684481B2 (en) | 1992-11-20 | 1993-11-18 | New oligopeptides with affinity to opioid receptors |
| DE69331499T DE69331499T2 (de) | 1992-11-20 | 1993-11-18 | Neue oligopeptide mit affinität für opioidrezeptoren |
| CA002149899A CA2149899A1 (en) | 1992-11-20 | 1993-11-18 | New oligopeptides with affinity to opioid receptors |
| FI952455A FI952455A0 (fi) | 1992-11-20 | 1995-05-19 | Uusia oligopeptidejä, joilla on affiniteetti opioidireseptoreihin |
| NO19951990A NO313098B1 (no) | 1992-11-20 | 1995-05-19 | Rettkjedete eller sykliske oligopeptider med affinitet for opioidreseptorer, samt farmasöytisk preparat og anvendelse avpeptidene |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9203496A SE9203496D0 (sv) | 1992-11-20 | 1992-11-20 | New oligopeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9203496D0 true SE9203496D0 (sv) | 1992-11-20 |
Family
ID=20387887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9203496A SE9203496D0 (sv) | 1992-11-20 | 1992-11-20 | New oligopeptides |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5872097A (xx) |
| EP (1) | EP0745093B1 (xx) |
| JP (1) | JP3470136B2 (xx) |
| AT (1) | ATE212357T1 (xx) |
| AU (1) | AU684481B2 (xx) |
| CA (1) | CA2149899A1 (xx) |
| DE (1) | DE69331499T2 (xx) |
| DK (1) | DK0745093T3 (xx) |
| ES (1) | ES2171445T3 (xx) |
| FI (1) | FI952455A0 (xx) |
| NO (1) | NO313098B1 (xx) |
| NZ (1) | NZ258260A (xx) |
| PT (1) | PT745093E (xx) |
| RU (1) | RU2131438C1 (xx) |
| SE (1) | SE9203496D0 (xx) |
| WO (1) | WO1994012532A1 (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001036006A1 (en) * | 1999-11-19 | 2001-05-25 | Palatin Technologies, Inc. | Opioid metallopeptide compositions and methods |
| US20080045610A1 (en) * | 2004-09-23 | 2008-02-21 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| AU2005286733B2 (en) * | 2004-09-23 | 2009-11-05 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| US7454406B2 (en) * | 2005-04-29 | 2008-11-18 | Adaptec, Inc. | System and method of handling file metadata |
| PT2590992T (pt) * | 2010-07-09 | 2017-07-26 | United States Dept Of Veterans Affairs | Análogos agonistas do recetor de opioides mu das endomorfinas |
| US20160176930A1 (en) | 2010-07-09 | 2016-06-23 | The Administrators Of The Tulane Educational Fund | Mu opioid receptor agonist analogs of the endomorphins |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8005121A (nl) * | 1979-09-20 | 1981-03-24 | Erba Farmitalia | Biologisch actieve peptiden. |
| US4254024A (en) * | 1979-10-16 | 1981-03-03 | Pennwalt Corporation | Tetrapeptides and derivatives having opiate activity |
| US4699897A (en) * | 1983-06-04 | 1987-10-13 | Amgen | Biologically active peptides structurally related to regions within growth hormones |
-
1992
- 1992-11-20 SE SE9203496A patent/SE9203496D0/xx unknown
-
1993
- 1993-11-08 US US08/433,401 patent/US5872097A/en not_active Expired - Fee Related
- 1993-11-18 WO PCT/SE1993/000986 patent/WO1994012532A1/en active IP Right Grant
- 1993-11-18 EP EP94901120A patent/EP0745093B1/en not_active Expired - Lifetime
- 1993-11-18 RU RU95113498A patent/RU2131438C1/ru not_active IP Right Cessation
- 1993-11-18 NZ NZ258260A patent/NZ258260A/en unknown
- 1993-11-18 ES ES94901120T patent/ES2171445T3/es not_active Expired - Lifetime
- 1993-11-18 DK DK94901120T patent/DK0745093T3/da active
- 1993-11-18 PT PT94901120T patent/PT745093E/pt unknown
- 1993-11-18 JP JP51303594A patent/JP3470136B2/ja not_active Expired - Fee Related
- 1993-11-18 CA CA002149899A patent/CA2149899A1/en not_active Abandoned
- 1993-11-18 DE DE69331499T patent/DE69331499T2/de not_active Expired - Fee Related
- 1993-11-18 AT AT94901120T patent/ATE212357T1/de not_active IP Right Cessation
- 1993-11-18 AU AU55816/94A patent/AU684481B2/en not_active Ceased
-
1995
- 1995-05-19 FI FI952455A patent/FI952455A0/fi not_active IP Right Cessation
- 1995-05-19 NO NO19951990A patent/NO313098B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE212357T1 (de) | 2002-02-15 |
| RU95113498A (ru) | 1997-03-20 |
| NO951990D0 (no) | 1995-05-19 |
| ES2171445T3 (es) | 2002-09-16 |
| FI952455A (fi) | 1995-05-19 |
| DK0745093T3 (da) | 2002-05-13 |
| DE69331499D1 (de) | 2002-03-14 |
| WO1994012532A1 (en) | 1994-06-09 |
| NZ258260A (en) | 1996-06-25 |
| US5872097A (en) | 1999-02-16 |
| JP3470136B2 (ja) | 2003-11-25 |
| JPH08507748A (ja) | 1996-08-20 |
| NO951990L (no) | 1995-05-19 |
| EP0745093B1 (en) | 2002-01-23 |
| CA2149899A1 (en) | 1994-06-09 |
| NO313098B1 (no) | 2002-08-12 |
| PT745093E (pt) | 2002-07-31 |
| AU5581694A (en) | 1994-06-22 |
| RU2131438C1 (ru) | 1999-06-10 |
| AU684481B2 (en) | 1997-12-18 |
| EP0745093A1 (en) | 1996-12-04 |
| FI952455A0 (fi) | 1995-05-19 |
| DE69331499T2 (de) | 2002-08-08 |
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