DE69331499T2 - Neue oligopeptide mit affinität für opioidrezeptoren - Google Patents

Neue oligopeptide mit affinität für opioidrezeptoren

Info

Publication number
DE69331499T2
DE69331499T2 DE69331499T DE69331499T DE69331499T2 DE 69331499 T2 DE69331499 T2 DE 69331499T2 DE 69331499 T DE69331499 T DE 69331499T DE 69331499 T DE69331499 T DE 69331499T DE 69331499 T2 DE69331499 T2 DE 69331499T2
Authority
DE
Germany
Prior art keywords
glu
gln
seq
pct
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69331499T
Other languages
English (en)
Other versions
DE69331499D1 (de
Inventor
Ingeborg Fhoelenhag
Linda Fryklund
Christer Larsson
Jarl Nyberg
Elisabeth Westin-Sjoedahl
Ronny Lundin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia AB filed Critical Pharmacia AB
Publication of DE69331499D1 publication Critical patent/DE69331499D1/de
Application granted granted Critical
Publication of DE69331499T2 publication Critical patent/DE69331499T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormones [GH] (Somatotropin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69331499T 1992-11-20 1993-11-18 Neue oligopeptide mit affinität für opioidrezeptoren Expired - Fee Related DE69331499T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9203496A SE9203496D0 (sv) 1992-11-20 1992-11-20 New oligopeptides
PCT/SE1993/000986 WO1994012532A1 (en) 1992-11-20 1993-11-18 New oligopeptides with affinity to opioid receptors

Publications (2)

Publication Number Publication Date
DE69331499D1 DE69331499D1 (de) 2002-03-14
DE69331499T2 true DE69331499T2 (de) 2002-08-08

Family

ID=20387887

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331499T Expired - Fee Related DE69331499T2 (de) 1992-11-20 1993-11-18 Neue oligopeptide mit affinität für opioidrezeptoren

Country Status (16)

Country Link
US (1) US5872097A (de)
EP (1) EP0745093B1 (de)
JP (1) JP3470136B2 (de)
AT (1) ATE212357T1 (de)
AU (1) AU684481B2 (de)
CA (1) CA2149899A1 (de)
DE (1) DE69331499T2 (de)
DK (1) DK0745093T3 (de)
ES (1) ES2171445T3 (de)
FI (1) FI952455A (de)
NO (1) NO313098B1 (de)
NZ (1) NZ258260A (de)
PT (1) PT745093E (de)
RU (1) RU2131438C1 (de)
SE (1) SE9203496D0 (de)
WO (1) WO1994012532A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1623801A (en) * 1999-11-19 2001-05-30 Palatin Technologies, Inc. Opioid metallopeptide compositions and methods
CA2580694A1 (en) * 2004-09-23 2006-03-30 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
US20080045610A1 (en) * 2004-09-23 2008-02-21 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
US7454406B2 (en) * 2005-04-29 2008-11-18 Adaptec, Inc. System and method of handling file metadata
HUE033875T2 (en) * 2010-07-09 2018-01-29 The Administrators Of The Tulane Educational Fund Anal opioid receptor agonist analogues of endomorphins
US20160176930A1 (en) 2010-07-09 2016-06-23 The Administrators Of The Tulane Educational Fund Mu opioid receptor agonist analogs of the endomorphins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005121A (nl) * 1979-09-20 1981-03-24 Erba Farmitalia Biologisch actieve peptiden.
US4254024A (en) * 1979-10-16 1981-03-03 Pennwalt Corporation Tetrapeptides and derivatives having opiate activity
US4699897A (en) * 1983-06-04 1987-10-13 Amgen Biologically active peptides structurally related to regions within growth hormones

Also Published As

Publication number Publication date
FI952455A0 (fi) 1995-05-19
RU95113498A (ru) 1997-03-20
PT745093E (pt) 2002-07-31
US5872097A (en) 1999-02-16
EP0745093B1 (de) 2002-01-23
EP0745093A1 (de) 1996-12-04
FI952455A (fi) 1995-05-19
CA2149899A1 (en) 1994-06-09
ES2171445T3 (es) 2002-09-16
NO313098B1 (no) 2002-08-12
NZ258260A (en) 1996-06-25
DE69331499D1 (de) 2002-03-14
RU2131438C1 (ru) 1999-06-10
NO951990D0 (no) 1995-05-19
JP3470136B2 (ja) 2003-11-25
AU684481B2 (en) 1997-12-18
NO951990L (no) 1995-05-19
WO1994012532A1 (en) 1994-06-09
SE9203496D0 (sv) 1992-11-20
JPH08507748A (ja) 1996-08-20
ATE212357T1 (de) 2002-02-15
AU5581694A (en) 1994-06-22
DK0745093T3 (da) 2002-05-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee