SE8301395L - Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler - Google Patents
Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekylerInfo
- Publication number
- SE8301395L SE8301395L SE8301395A SE8301395A SE8301395L SE 8301395 L SE8301395 L SE 8301395L SE 8301395 A SE8301395 A SE 8301395A SE 8301395 A SE8301395 A SE 8301395A SE 8301395 L SE8301395 L SE 8301395L
- Authority
- SE
- Sweden
- Prior art keywords
- bio
- covalent coupling
- kelatizing
- compounds
- functional groups
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000008878 coupling Effects 0.000 title abstract 2
- 238000010168 coupling process Methods 0.000 title abstract 2
- 238000005859 coupling reaction Methods 0.000 title abstract 2
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C07F9/3817—Acids containing the structure (RX)2P(=X)-alk-N...P (X = O, S, Se)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/40—Rare earth chelates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8301395A SE8301395L (sv) | 1983-03-15 | 1983-03-15 | Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler |
DE8484901128T DE3462252D1 (en) | 1983-03-15 | 1984-03-13 | Compound |
JP59501184A JPS60500767A (ja) | 1983-03-15 | 1984-03-13 | 生特異的親和反応の定量方法 |
PCT/SE1984/000089 WO1984003698A1 (fr) | 1983-03-15 | 1984-03-13 | Compose |
EP84901128A EP0139675B1 (fr) | 1983-03-15 | 1984-03-13 | Compose |
US07/016,789 US4808541A (en) | 1983-03-15 | 1987-02-20 | Determination method utilizing reagents covalently labelled with essentially non-fluorescent lanthanide chelates in combination with time-resolved fluorescence spectroscopy and the reagents to be used in the method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8301395A SE8301395L (sv) | 1983-03-15 | 1983-03-15 | Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8301395D0 SE8301395D0 (sv) | 1983-03-15 |
SE8301395L true SE8301395L (sv) | 1984-09-16 |
Family
ID=20350368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8301395A SE8301395L (sv) | 1983-03-15 | 1983-03-15 | Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler |
Country Status (6)
Country | Link |
---|---|
US (1) | US4808541A (fr) |
EP (1) | EP0139675B1 (fr) |
JP (1) | JPS60500767A (fr) |
DE (1) | DE3462252D1 (fr) |
SE (1) | SE8301395L (fr) |
WO (1) | WO1984003698A1 (fr) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5064633A (en) * | 1984-06-04 | 1991-11-12 | The Dow Chemical Company | Macrocyclic aminophosphonic acid complexes, their formulations and use |
US5585279A (en) * | 1986-01-23 | 1996-12-17 | Davidson; Robert S. | Time-resolved luminescence binding assays using a fluorescent transition metal label other than ruthenium |
GB8601646D0 (en) * | 1986-01-23 | 1986-02-26 | Davidson R S | Binding assay & reagent |
IT1213029B (it) * | 1986-01-30 | 1989-12-07 | Bracco Ind Chimica Spa | Chelati di ioni metallici paramagnetici. |
EP0484989B1 (fr) * | 1986-09-05 | 1996-04-24 | GANSOW, Otto A. | Chélates de diéthylaminetriamine polysubstituée pour la formation d'une conjugaison métal-chélate-protein |
US4831175A (en) * | 1986-09-05 | 1989-05-16 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
US5099069A (en) * | 1986-09-05 | 1992-03-24 | Gansow Otto A | Backbone polysubstituted chelates for forming a metal chelate-protein conjugate |
SE454781B (sv) * | 1986-10-17 | 1988-05-30 | Wallac Oy | Hybridiseringsforfarande for detektion av polynukleotidsekvens |
US5006643A (en) * | 1987-06-24 | 1991-04-09 | The Dow Chemical Company | Process for preparing isothiocyanato functionalized metal complexes |
SE8703682L (sv) * | 1987-09-24 | 1989-03-25 | Wallac Oy | Homogen bestaemningsmetod som utnyttjar affinitetsreaktioner |
US4962045A (en) * | 1988-05-02 | 1990-10-09 | The Perkin-Elmer Corporation | Time-resolved fluorimetric detection of lanthanide labeled nucleotides |
CN1033030C (zh) * | 1988-06-24 | 1996-10-16 | 唐化学原料公司 | 大环双官能螯合剂及其配合物和抗体共轭物的制备方法 |
US5756065A (en) * | 1988-06-24 | 1998-05-26 | The Dow Chemical Company | Macrocyclic tetraazacyclododecane conjugates and their use as diagnostic and therapeutic agents |
DE353450T1 (de) * | 1988-06-24 | 1990-09-06 | The Dow Chemical Co., Midland, Mich. | Macrocyclische bifunktionelle chelatbildner, komplexe davon und ihre konjugierten antikoerper. |
NZ231180A (en) | 1988-10-31 | 1994-11-25 | Dow Chemical Co | Bifunctional chelants;complexes,conjugates and pharmaceutical compositions thereof |
BR8907282A (pt) * | 1988-12-23 | 1991-03-12 | Dow Chemical Co | Processo para preparar complexos de metal funcionalizados com isotiocianato |
ATE128035T1 (de) * | 1989-05-26 | 1995-10-15 | Akzo Nobel Nv | Chelatierungsmittel zur bindung von metallionen zu proteinen. |
US5808003A (en) * | 1989-05-26 | 1998-09-15 | Perimmune Holdings, Inc. | Polyaminocarboxylate chelators |
US5292868A (en) * | 1989-05-26 | 1994-03-08 | Akzo N.V. | Chelating agents for attaching metal ions to proteins |
GB8927503D0 (en) * | 1989-12-04 | 1990-02-07 | Kronem Systems Inc | Enzyme-amplified lanthanide chelate luminescence |
EP0493745A1 (fr) * | 1990-12-21 | 1992-07-08 | Dojindo Laboratories | Composé fluorescent, complexe, réactif et test de liaison spécifique |
ES2108109T3 (es) * | 1991-02-14 | 1997-12-16 | Dade Microscan Inc | Nuevos oligonucleotidos conjugados con quelatos de lantanidos. |
FI88654C (fi) * | 1991-03-15 | 1993-06-10 | Datacity Center Oy | Fluorescenshoejningsmetod |
DE4136489A1 (de) * | 1991-11-06 | 1993-05-13 | Bayer Ag | Neue diethylentriamin-derivate und deren verwendung zu diagnostischen und therapeutischen zwecken |
CA2180662A1 (fr) * | 1994-01-07 | 1995-07-13 | Ramaswamy Subramanian | Nouveaux chelateurs de polyaminocarboxylate |
DE19507820A1 (de) * | 1995-02-21 | 1996-08-22 | Schering Ag | Neuartig substituierte DTPA-Derivate, deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel |
US20050227294A1 (en) * | 1997-09-15 | 2005-10-13 | Molecular Devices Corporation | Molecular modification assays involving lipids |
US7745142B2 (en) * | 1997-09-15 | 2010-06-29 | Molecular Devices Corporation | Molecular modification assays |
US7070921B2 (en) | 2000-04-28 | 2006-07-04 | Molecular Devices Corporation | Molecular modification assays |
US7632651B2 (en) * | 1997-09-15 | 2009-12-15 | Mds Analytical Technologies (Us) Inc. | Molecular modification assays |
US6030840A (en) * | 1998-06-15 | 2000-02-29 | Nen Life Sciences, Inc. | Neutral enhancement of lanthanides for time resolved fluorescence |
DE19954934A1 (de) * | 1999-11-16 | 2001-05-17 | Otto S Wolfbeis | Verfahren zur Solubilisierung von optischen Markern |
EP1191948A2 (fr) * | 1999-06-11 | 2002-04-03 | Neorx Corporation | Complexe a forte dose de radionucleides destine a la suppression de la moelle osseuse |
US7094885B2 (en) * | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
US6440389B1 (en) | 2000-07-19 | 2002-08-27 | The General Hospital Corporation | Fluorescent agents for real-time measurement of organ function |
JP2004536034A (ja) | 2001-01-08 | 2004-12-02 | ネオルクス コーポレイション | 治療的および診断的化合物、組成物および方法 |
US20030215391A1 (en) * | 2001-07-19 | 2003-11-20 | Carlos Rabito | Fluorescent agents for real-time measurement of organ function |
US7211440B2 (en) | 2002-03-08 | 2007-05-01 | Wallac Oy | Dissociative fluorescence enhancement assay |
EP2267154A1 (fr) | 2003-10-23 | 2010-12-29 | Illumigen Biosciences, Inc. | Oligoadenylate synthétase |
DE102004022628A1 (de) * | 2004-05-07 | 2005-12-15 | Sensient Imaging Technologies Gmbh | FRET-Bioassay |
CA2581639C (fr) * | 2004-09-30 | 2016-07-26 | Molecular Devices Corporation | Complexes de lanthanides luminescents |
US7482444B2 (en) | 2006-03-13 | 2009-01-27 | Wallac Oy | Terminating substrates for DNA polymerases |
US8778614B2 (en) | 2010-08-24 | 2014-07-15 | Enzo Life Sciences, Inc. | Assays for detecting modified compounds |
GB201018361D0 (en) | 2010-11-01 | 2010-12-15 | Thompson Edward J | Fluorometry |
JP6153951B2 (ja) | 2012-03-16 | 2017-06-28 | スタット−ダイアグノスティカ アンド イノベーション, エス. エル. | 統合された移送モジュールを有する試験カートリッジ |
FI125102B (en) * | 2013-11-19 | 2015-06-15 | Kemira Oyj | Method for the determination of an antifouling agent in a sample |
FI125111B (en) * | 2013-11-19 | 2015-06-15 | Kemira Oyj | A method for analyzing a sample comprising a first and a second crust inhibitor |
US9834808B2 (en) | 2016-01-21 | 2017-12-05 | SeLux Diagnostics, Inc. | Methods for rapid antibiotic susceptibility testing |
CA3010895A1 (fr) | 2016-01-21 | 2017-07-27 | SeLux Diagnostics, Inc. | Procedes de test rapide de la sensibilite antimicrobienne |
JP7146765B2 (ja) | 2016-12-23 | 2022-10-04 | セルックス・ダイアグノスティクス・インコーポレイテッド | 改善された迅速な抗菌薬感受性試験のための方法 |
US11845976B2 (en) | 2019-08-27 | 2023-12-19 | SeLux Diagnostics, Inc. | Systems and methods for performing antimicrobial susceptibility testing |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB723316A (en) * | 1951-06-11 | 1955-02-09 | Frederick Charles Bersworth | Substituted alkylene polyamine acetic acid compounds |
DE2015022C3 (de) * | 1970-03-28 | 1979-03-29 | Joh. A. Benckiser Gmbh, 6700 Ludwigshafen | Mittel zum Stabilisieren der Wasserhärte, insbesondere in Reinigungslösungen |
CH572461A5 (fr) * | 1970-12-18 | 1976-02-13 | Basf Ag | |
DE2150994C3 (de) * | 1971-10-13 | 1980-06-04 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung reiner Alkalisalze von Aminopolycarbonsauren |
BE785964A (fr) * | 1971-07-07 | 1973-01-08 | Monsanto Co | Derives condenses de polyalkylenepolyamines |
CH575909A5 (fr) * | 1972-08-21 | 1976-05-31 | Ciba Geigy Ag | |
US3994966A (en) * | 1972-09-28 | 1976-11-30 | The Board Of Trustees Of The Leland Stanford Junior University | Chelating agents |
NL7404829A (fr) * | 1973-04-14 | 1974-10-16 | ||
DE2357278B2 (de) * | 1973-11-16 | 1978-09-07 | Hoechst Ag, 6000 Frankfurt | Ampholyte, Verfahren zu ihrer Herstellung und diese enthaltende Wasch-, Reinigungs- und Desinfektionsmittel |
US3974090A (en) * | 1975-03-20 | 1976-08-10 | Monsanto Company | Imino alkylimino phosphonates and method for preparing and using same |
DE2523209A1 (de) * | 1975-05-26 | 1976-12-16 | Noeller Hans Guenter Dr Med | Elektrooptische, substanzschonende erfassung von nicht zellgebundenen immunostoffen |
US4058732A (en) * | 1975-06-30 | 1977-11-15 | Analytical Radiation Corporation | Method and apparatus for improved analytical fluorescent spectroscopy |
US4341957A (en) * | 1975-11-26 | 1982-07-27 | Analytical Radiation Corporation | Fluorescent antibody composition for immunofluorometric assay |
US4228184A (en) * | 1976-05-10 | 1980-10-14 | E. R. Squibb & Sons, Inc. | Carboxyalkylacylamino acids |
US4144224A (en) * | 1976-11-26 | 1979-03-13 | Ciba-Geigy Corporation | Phosphonate stabilizers |
IT1088581B (it) * | 1977-12-02 | 1985-06-10 | Montedison Spa | Stabilizzanti per polimeri e composizioni polimeriche con essi stabilizzate |
GB1598610A (en) * | 1978-05-31 | 1981-09-23 | Rexolin Chem Ab | Aliphatic polyamino polycarboxylic acid and its salts and their use as chelating agents |
US4259313A (en) * | 1978-10-18 | 1981-03-31 | Eastman Kodak Company | Fluorescent labels |
SE428332B (sv) * | 1979-03-08 | 1983-06-20 | Wallac Oy | Forfarande for fluorescensspektroskopisk bestemning av biologiskt aktivt emne, sasom hapten, antikropp eller antigen |
US4352751A (en) * | 1979-09-10 | 1982-10-05 | Analytical Radiation Corporation | Species-linked diamine triacetic acids and their chelates |
FR2470820A1 (fr) * | 1979-11-30 | 1981-06-12 | Lafarge Sa | Procede de fabrication de charges minerales contenant du monocarboaluminate de calcium hydrate |
SE425439B (sv) * | 1981-04-30 | 1982-09-27 | Wallac Oy | Immunologisk analys med lantanidkelatkomplex som markor |
DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
SE9502789D0 (sv) * | 1995-08-09 | 1995-08-09 | Hans Tillander | Tryckinfusionsapparat |
ATE221539T1 (de) * | 1995-09-15 | 2002-08-15 | Organon Teknika Bv | Toxoplasma gondii glykokonjugate |
-
1983
- 1983-03-15 SE SE8301395A patent/SE8301395L/xx not_active Application Discontinuation
-
1984
- 1984-03-13 WO PCT/SE1984/000089 patent/WO1984003698A1/fr active IP Right Grant
- 1984-03-13 JP JP59501184A patent/JPS60500767A/ja active Granted
- 1984-03-13 EP EP84901128A patent/EP0139675B1/fr not_active Expired
- 1984-03-13 DE DE8484901128T patent/DE3462252D1/de not_active Expired
-
1987
- 1987-02-20 US US07/016,789 patent/US4808541A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0139675A1 (fr) | 1985-05-08 |
EP0139675B1 (fr) | 1987-01-28 |
US4808541A (en) | 1989-02-28 |
WO1984003698A1 (fr) | 1984-09-27 |
JPH0377463B2 (fr) | 1991-12-10 |
DE3462252D1 (en) | 1987-03-05 |
SE8301395D0 (sv) | 1983-03-15 |
JPS60500767A (ja) | 1985-05-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 8301395-3 Effective date: 19891109 |