DE3462252D1 - Compound - Google Patents

Compound

Info

Publication number
DE3462252D1
DE3462252D1 DE8484901128T DE3462252T DE3462252D1 DE 3462252 D1 DE3462252 D1 DE 3462252D1 DE 8484901128 T DE8484901128 T DE 8484901128T DE 3462252 T DE3462252 T DE 3462252T DE 3462252 D1 DE3462252 D1 DE 3462252D1
Authority
DE
Germany
Prior art keywords
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484901128T
Other languages
English (en)
Inventor
Heikki Mikola
Veli-Matti Mukkala
Ilkka Hemmila
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wallac Oy
Original Assignee
Wallac Oy
LKB Produkter AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallac Oy, LKB Produkter AB filed Critical Wallac Oy
Application granted granted Critical
Publication of DE3462252D1 publication Critical patent/DE3462252D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • C07F9/3817—Acids containing the structure (RX)2P(=X)-alk-N...P (X = O, S, Se)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/40—Rare earth chelates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE8484901128T 1983-03-15 1984-03-13 Compound Expired DE3462252D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8301395A SE8301395L (sv) 1983-03-15 1983-03-15 Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler
PCT/SE1984/000089 WO1984003698A1 (en) 1983-03-15 1984-03-13 Compound

Publications (1)

Publication Number Publication Date
DE3462252D1 true DE3462252D1 (en) 1987-03-05

Family

ID=20350368

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484901128T Expired DE3462252D1 (en) 1983-03-15 1984-03-13 Compound

Country Status (6)

Country Link
US (1) US4808541A (de)
EP (1) EP0139675B1 (de)
JP (1) JPS60500767A (de)
DE (1) DE3462252D1 (de)
SE (1) SE8301395L (de)
WO (1) WO1984003698A1 (de)

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US4831175A (en) * 1986-09-05 1989-05-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
US5099069A (en) * 1986-09-05 1992-03-24 Gansow Otto A Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
EP0529645B1 (de) * 1986-09-05 1996-10-23 GANSOW, Otto A. Verfahren zur Herstellung hauptkettenpolysubstituierter Chelate
SE454781B (sv) * 1986-10-17 1988-05-30 Wallac Oy Hybridiseringsforfarande for detektion av polynukleotidsekvens
US5006643A (en) * 1987-06-24 1991-04-09 The Dow Chemical Company Process for preparing isothiocyanato functionalized metal complexes
SE8703682L (sv) * 1987-09-24 1989-03-25 Wallac Oy Homogen bestaemningsmetod som utnyttjar affinitetsreaktioner
US4962045A (en) * 1988-05-02 1990-10-09 The Perkin-Elmer Corporation Time-resolved fluorimetric detection of lanthanide labeled nucleotides
ZA894792B (en) * 1988-06-24 1991-04-24 Dow Chemical Co Macrocyclic bifunctional chelants,complexes thereof and their antibody conjugates
HU219485B (hu) * 1988-06-24 2001-04-28 Dow Chemical Co. Eljárás 1,4,7,10-tetraaza-ciklododekán-származékok, ezek komplexei, valamint antitestekkel képzett konjugátumai, és ilyeneket tartalmazó gyógyszerkészítmények előállítására és a komplexeket, illetve konjugátumokat tartalmazó diagnosztikai készítmények
US5756065A (en) * 1988-06-24 1998-05-26 The Dow Chemical Company Macrocyclic tetraazacyclododecane conjugates and their use as diagnostic and therapeutic agents
IE980697A1 (en) 1988-10-31 2000-12-13 Dow Chemical Co Chelants possessing ortho ligating functionality and complexes thereof
JP2930708B2 (ja) * 1988-12-23 1999-08-03 ザ ダウ ケミカル カンパニー イソチオシアナト官能化金属錯体の製造方法
ATE128035T1 (de) * 1989-05-26 1995-10-15 Akzo Nobel Nv Chelatierungsmittel zur bindung von metallionen zu proteinen.
US5292868A (en) * 1989-05-26 1994-03-08 Akzo N.V. Chelating agents for attaching metal ions to proteins
US5808003A (en) * 1989-05-26 1998-09-15 Perimmune Holdings, Inc. Polyaminocarboxylate chelators
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EP0493745A1 (de) * 1990-12-21 1992-07-08 Dojindo Laboratories Fluoreszierende Verbindung, Komplex, Reagenz und spezifische Bindungtest
AU653012B2 (en) * 1991-02-14 1994-09-15 Microscan, Inc. Novel lanthanide chelate-conjugated oligonucleotides
FI88654C (fi) * 1991-03-15 1993-06-10 Datacity Center Oy Fluorescenshoejningsmetod
DE4136489A1 (de) * 1991-11-06 1993-05-13 Bayer Ag Neue diethylentriamin-derivate und deren verwendung zu diagnostischen und therapeutischen zwecken
CA2180662A1 (en) * 1994-01-07 1995-07-13 Ramaswamy Subramanian New polyaminocarboxylate chelators
DE19507820A1 (de) 1995-02-21 1996-08-22 Schering Ag Neuartig substituierte DTPA-Derivate, deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel
US7745142B2 (en) * 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US20050227294A1 (en) * 1997-09-15 2005-10-13 Molecular Devices Corporation Molecular modification assays involving lipids
US7632651B2 (en) * 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
US6030840A (en) * 1998-06-15 2000-02-29 Nen Life Sciences, Inc. Neutral enhancement of lanthanides for time resolved fluorescence
DE19954934A1 (de) * 1999-11-16 2001-05-17 Otto S Wolfbeis Verfahren zur Solubilisierung von optischen Markern
AU5871000A (en) * 1999-06-11 2001-01-02 Paul G. Abrams High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) * 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
US6440389B1 (en) * 2000-07-19 2002-08-27 The General Hospital Corporation Fluorescent agents for real-time measurement of organ function
JP2004536034A (ja) 2001-01-08 2004-12-02 ネオルクス コーポレイション 治療的および診断的化合物、組成物および方法
US20030215391A1 (en) * 2001-07-19 2003-11-20 Carlos Rabito Fluorescent agents for real-time measurement of organ function
US7211440B2 (en) 2002-03-08 2007-05-01 Wallac Oy Dissociative fluorescence enhancement assay
CN1910293B (zh) 2003-10-23 2011-04-13 伊洛默格生物科学公司 检测与抗病毒感染性有关的基因oas1中的突变的方法
DE102004022628A1 (de) * 2004-05-07 2005-12-15 Sensient Imaging Technologies Gmbh FRET-Bioassay
EP1805188A4 (de) * 2004-09-30 2010-03-03 Mds Analytical Technologies Us Lumineszente lanthanidkomplexe
US7482444B2 (en) 2006-03-13 2009-01-27 Wallac Oy Terminating substrates for DNA polymerases
US8778614B2 (en) 2010-08-24 2014-07-15 Enzo Life Sciences, Inc. Assays for detecting modified compounds
GB201018361D0 (en) 2010-11-01 2010-12-15 Thompson Edward J Fluorometry
CN107083319A (zh) 2012-03-16 2017-08-22 统计诊断与创新有限公司 具有集成传送模块的测试盒
FI125111B (en) * 2013-11-19 2015-06-15 Kemira Oyj A method for analyzing a sample comprising a first and a second crust inhibitor
FI125102B (en) * 2013-11-19 2015-06-15 Kemira Oyj Method for the determination of an antifouling agent in a sample
AU2017210215B2 (en) 2016-01-21 2022-09-08 SeLux Diagnostics, Inc. Methods for rapid antimicrobial susceptibility testing
US9834808B2 (en) 2016-01-21 2017-12-05 SeLux Diagnostics, Inc. Methods for rapid antibiotic susceptibility testing
CN110603333A (zh) 2016-12-23 2019-12-20 赛录科试诊断公司 用于改进的快速抗微生物剂敏感性测试的方法
AU2020340381A1 (en) 2019-08-27 2022-04-07 SeLux Diagnostics, Inc. Systems and methods for performing antimicrobial susceptibility testing

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Also Published As

Publication number Publication date
SE8301395D0 (sv) 1983-03-15
EP0139675B1 (de) 1987-01-28
US4808541A (en) 1989-02-28
JPS60500767A (ja) 1985-05-23
SE8301395L (sv) 1984-09-16
JPH0377463B2 (de) 1991-12-10
EP0139675A1 (de) 1985-05-08
WO1984003698A1 (en) 1984-09-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: WALLAC OY, TURKU, FI

8328 Change in the person/name/address of the agent

Free format text: PFENNING, J., DIPL.-ING., 10707 BERLIN MEINIG, K., DIPL.-PHYS., 80336 MUENCHEN BUTENSCHOEN, A., DIPL.-ING. DR.-ING., PAT.-ANWAELTE BERGMANN, J., DIPL.-ING., PAT.- U. RECHTSANW., 10707 BERLIN NOETH, H., DIPL.-PHYS., 80336 MUENCHEN HENGELHAUPT, J., DIPL.-ING., 01097 DRESDEN KRAUS, H., DIPL.-PHYS. REITZLE, H., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 80336 MUENCHEN