GB723316A - Substituted alkylene polyamine acetic acid compounds - Google Patents
Substituted alkylene polyamine acetic acid compoundsInfo
- Publication number
- GB723316A GB723316A GB1380351A GB1380351A GB723316A GB 723316 A GB723316 A GB 723316A GB 1380351 A GB1380351 A GB 1380351A GB 1380351 A GB1380351 A GB 1380351A GB 723316 A GB723316 A GB 723316A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- alkylene
- amino
- alanine
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L21/00—Compositions of unspecified rubbers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention relates to alkylene polyamine polyacetic acid compounds having the general formula <FORM:0723316/IV (b)/1> wherein R is an alkyl or substituted alkyl group containing 1 to 18 carbon atoms, Alkylene represents -CH2.CH2-, CH3-CH-CH2-, <FORM:0723316/IV (b)/2> , n is 0, 1 or 2 and M is H, NH4, K, Na or an amine. They may be prepared by various methods. Thus, an appropriate a -amino-acid salt (2 mols.) may be reacted with 1 mol. of an alkylene dihalide X-alkylene-(NH-Alkylene)n-X, wherein X is a halogen and Alkylene and n have the above meanings and the product is then N-alkylated by means of an alkali-metal chloroacetate in alkaline solution or as described in Specification 600,629, forming the desired polyacetic derivative which may be isolated in the form of the free acid or above-specified salts. A second method comprises reacting a salt of an appropriate a -halo acid (2 mols.) with 1 mol. of a polyamine NH2-Alkylene-(NH-Alkylene)n-NH2, n and Alkylene having the above meanings and the product is then N-alkylated as before. A third method involves the use of an appropriate a -hydroxy acid salt in method (2). The products are chelating agents; the salts are surface tension reducing and foaming agents; the free acids may be used as anti-oxidants in fats, oils and fatty acids. Some may be used as plasticizers and co-polymerizing emulsants. In examples, (1) alanine sodium salt is reacted with ethylene dibromide in aqueous medium at pH 10 and the resulting ethylene diamine-di-alanine is recovered as free acid on acidification and is reacted with sodium chloracetate in aqueous solution yielding on acidification ethylene diamine-bis-alanine-N,N1-di-acetic acid; (2) ethylene bis-(a -amino caproic acid)-N : N1-di-acetic acid is obtained in like manner using a -amino caproic acid sodium or potassium salt in place of sodium alanine; leucine and iso-leucine may be used similarly; (3) a -amino undecanoic acid; and (4) an a -amino C9 branched chain acid are used as in (1); (5) an a -amino C10 branched chain acid is used as in (1) the first stage, however, being effected in n-butyl alcohol. The properties of the partial sodium and potassium salts of various of these products are discussed. Many other a -amino acid reactants are mentioned including a -amino butyric and a -amino valeric acids and serine, phenyl-alanine, tyrosine, valine, tryptophane, cysteine, cystine and methionine.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1380351A GB723316A (en) | 1951-06-11 | 1951-06-11 | Substituted alkylene polyamine acetic acid compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1380351A GB723316A (en) | 1951-06-11 | 1951-06-11 | Substituted alkylene polyamine acetic acid compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GB723316A true GB723316A (en) | 1955-02-09 |
Family
ID=10029675
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1380351A Expired GB723316A (en) | 1951-06-11 | 1951-06-11 | Substituted alkylene polyamine acetic acid compounds |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB723316A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984003698A1 (en) * | 1983-03-15 | 1984-09-27 | Lkb Produkter Ab | Compound |
WO1989010758A1 (en) * | 1988-05-02 | 1989-11-16 | Zynaxis Technologies, Inc. | Compounds, compositions and method for binding bio-affecting substances to surface membranes of bio-particles |
US4920195A (en) * | 1985-05-23 | 1990-04-24 | Jouko Kankare | Fluorescent lanthanide chelates |
US4980502A (en) * | 1986-01-30 | 1990-12-25 | Bracco Industria Chimica, S.P.A. | Paramagnetic chelates |
US5438057A (en) * | 1991-07-12 | 1995-08-01 | British Technology Group Limited | Pharmaceutical compositions |
-
1951
- 1951-06-11 GB GB1380351A patent/GB723316A/en not_active Expired
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984003698A1 (en) * | 1983-03-15 | 1984-09-27 | Lkb Produkter Ab | Compound |
US4808541A (en) * | 1983-03-15 | 1989-02-28 | Lkb Produkter Ab | Determination method utilizing reagents covalently labelled with essentially non-fluorescent lanthanide chelates in combination with time-resolved fluorescence spectroscopy and the reagents to be used in the method |
US4920195A (en) * | 1985-05-23 | 1990-04-24 | Jouko Kankare | Fluorescent lanthanide chelates |
US4980502A (en) * | 1986-01-30 | 1990-12-25 | Bracco Industria Chimica, S.P.A. | Paramagnetic chelates |
WO1989010758A1 (en) * | 1988-05-02 | 1989-11-16 | Zynaxis Technologies, Inc. | Compounds, compositions and method for binding bio-affecting substances to surface membranes of bio-particles |
US5665328A (en) * | 1988-05-02 | 1997-09-09 | Phanos Technologies, Inc. | Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles |
US5438057A (en) * | 1991-07-12 | 1995-08-01 | British Technology Group Limited | Pharmaceutical compositions |
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