SE7908126L - Forfarande for framstellning av prostaglandiner - Google Patents

Forfarande for framstellning av prostaglandiner

Info

Publication number
SE7908126L
SE7908126L SE7908126A SE7908126A SE7908126L SE 7908126 L SE7908126 L SE 7908126L SE 7908126 A SE7908126 A SE 7908126A SE 7908126 A SE7908126 A SE 7908126A SE 7908126 L SE7908126 L SE 7908126L
Authority
SE
Sweden
Prior art keywords
prostaglandins
procedure
production
series
attached
Prior art date
Application number
SE7908126A
Other languages
English (en)
Inventor
T K Schaaf
E J Corey
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SE7908126L publication Critical patent/SE7908126L/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)

Claims (1)

1. Nya cyklopentanderivat anvAndbara a8som mellanprodukt for framst811ning av prostaglandinanaloger, kannetecknade av formeln Picture V. van i R3 betecknar tetrahydropyranyl, tetrahydrofuranyl elder dimetylieopropyleily1 och R4 och R3 vardera betecknar alkyl med 1-8 kolatomer, fenylalkyl med upp till 3 kolatomer i alkyldelen, fenyl, tolyl, bifenyl, fluorenyl ellera(- eller/l-naftyl.
SE7908126A 1972-04-17 1979-10-01 Forfarande for framstellning av prostaglandiner SE7908126L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US244882A US3887587A (en) 1972-04-17 1972-04-17 Synthesis of prostaglandins of the one-series

Publications (1)

Publication Number Publication Date
SE7908126L true SE7908126L (sv) 1979-10-01

Family

ID=22924496

Family Applications (4)

Application Number Title Priority Date Filing Date
SE7304635A SE416543B (sv) 1972-04-17 1973-04-02 Sibstituerat cyklopentanderivat till anvendning som mellanprodukt vid framstellning av farmaceutiskt aktiva prostaglandinanaloger
SE7609048A SE7609048L (sv) 1972-04-17 1976-08-12 Forfarande for framstellning av prostaglandiner
SE7908126A SE7908126L (sv) 1972-04-17 1979-10-01 Forfarande for framstellning av prostaglandiner
SE7908125A SE7908125L (sv) 1972-04-17 1979-10-01 Forfarande for framstellning av prostaglandiner

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7304635A SE416543B (sv) 1972-04-17 1973-04-02 Sibstituerat cyklopentanderivat till anvendning som mellanprodukt vid framstellning av farmaceutiskt aktiva prostaglandinanaloger
SE7609048A SE7609048L (sv) 1972-04-17 1976-08-12 Forfarande for framstellning av prostaglandiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7908125A SE7908125L (sv) 1972-04-17 1979-10-01 Forfarande for framstellning av prostaglandiner

Country Status (19)

Country Link
US (1) US3887587A (sv)
JP (1) JPS5710104B2 (sv)
AR (2) AR197135A1 (sv)
AT (1) AT336809B (sv)
AU (1) AU470252B2 (sv)
BE (1) BE798316A (sv)
CA (1) CA999579A (sv)
CH (2) CH578497A5 (sv)
DE (1) DE2319017C3 (sv)
ES (2) ES413786A1 (sv)
FR (3) FR2183711B1 (sv)
GB (4) GB1424416A (sv)
IE (2) IE37495B1 (sv)
NL (1) NL160250C (sv)
PL (2) PL103097B1 (sv)
SE (4) SE416543B (sv)
SU (1) SU580834A3 (sv)
YU (1) YU36924B (sv)
ZA (1) ZA732385B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4243595A (en) * 1972-07-13 1981-01-06 Pfizer Inc. 15-Substituted-omega-pentanorprostaglandins
GB1432950A (en) * 1972-11-10 1976-04-22 Ici Ltd Cyclopentane aldehydes as chemical intermediates
US4737590A (en) * 1973-04-27 1988-04-12 American Cyanamid Company Novel 2-substituted-3,4-epoxycyclopentan-1-ones, 2-substituted-3,4-epoxycyclopentan-1-ols, and various 2-substituted-cyclopentenones
US4012431A (en) * 1973-05-21 1977-03-15 The Upjohn Company Process for preparing 5-oxa PGF1.sub.α -type compounds
US4060540A (en) * 1975-09-18 1977-11-29 American Cyanamid Company Novel 3-triphenylmethoxy-1-alkynes, 3-triphenyl-methoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates
US4039574A (en) * 1975-09-25 1977-08-02 American Cyanamid Company 13-Hydroxy-15-deoxy-prostaglandins
US4219483A (en) * 1978-09-11 1980-08-26 Pfizer Inc. 4-Pyrone prostaglandin antagonists
JPH0964603A (ja) * 1995-08-26 1997-03-07 Nec Corp 温度補償型位相遅延回路
CN103570599B (zh) * 2013-11-11 2015-05-06 陕西大生制药科技有限公司 前列腺素a1的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA959485A (en) * 1970-05-04 1974-12-17 Gordon L. Bundy 15-alkyl prostaglandins
US3736335A (en) * 1970-06-22 1973-05-29 Merck & Co Inc Prostaglandins and methods of making same
DE2166721A1 (de) * 1970-09-11 1975-05-15 Upjohn Co Prostansaeurederivate und deren herstellung
CA951723A (en) * 1970-09-19 1974-07-23 Takashi Yusa Prostaglandin derivatives and process for the preparation thereof
GB1356581A (en) * 1970-10-09 1974-06-12 Ici Ltd Cyclopentane derivatives

Also Published As

Publication number Publication date
AT336809B (de) 1977-05-25
SE7609048L (sv) 1976-08-12
AR204713A1 (es) 1976-02-27
CH578497A5 (sv) 1976-08-13
AR197135A1 (es) 1974-03-15
ES413786A1 (es) 1977-05-01
FR2183711B1 (sv) 1978-06-30
AU470252B2 (en) 1976-03-11
GB1424415A (en) 1976-02-11
ZA732385B (en) 1974-01-30
JPS4914446A (sv) 1974-02-07
PL103097B1 (pl) 1979-05-31
FR2275453B1 (sv) 1978-06-30
GB1424417A (en) 1976-02-11
DE2319017B2 (de) 1978-06-08
PL196152A1 (pl) 1978-01-02
CA999579A (en) 1976-11-09
DE2319017A1 (de) 1973-10-31
PL99374B1 (pl) 1978-07-31
IE37496B1 (en) 1977-08-03
GB1424414A (en) 1976-02-11
IE37495B1 (en) 1977-08-03
BE798316A (fr) 1973-10-17
IE37495L (en) 1973-10-17
DE2319017C3 (de) 1979-02-01
SU580834A3 (ru) 1977-11-15
NL160250B (nl) 1979-05-15
JPS5710104B2 (sv) 1982-02-24
FR2275473B1 (sv) 1979-06-15
ATA341273A (de) 1976-09-15
FR2275453A1 (fr) 1976-01-16
NL160250C (nl) 1979-10-15
CH568264A5 (sv) 1975-10-31
NL7305292A (sv) 1973-10-19
FR2275473A1 (fr) 1976-01-16
AU5428273A (en) 1974-10-10
ES444110A1 (es) 1977-04-16
SE7908125L (sv) 1979-10-01
FR2183711A1 (sv) 1973-12-21
US3887587A (en) 1975-06-03
YU36924B (en) 1984-08-31
YU103373A (en) 1982-06-18
SE416543B (sv) 1981-01-19
GB1424416A (en) 1976-02-11

Similar Documents

Publication Publication Date Title
GB1452182A (en) Crown compounds and processes for their preparation
SE7908126L (sv) Forfarande for framstellning av prostaglandiner
RO72872B (ro) Procedeu pentru prepararea derivatilor acidului aminocarbonil tiobarbituric
ES418924A1 (es) Procedimiento para la obtencion de 13, 14-dihidroprosta- glandinas.
BE829999A (fr) Procede de synthese de l'ether-oxyde de bis (2-n,n-dimethylam ino)ethyle)
JPS5271456A (en) Synthesis of 1alpha-hydroxysteroid derivatives
SE7706245L (sv) Forfarande for framstellning av prostacyklinderivat
GB1421555A (en) Process for the stereoselective production of intermediates in the synthesis of pge1 and derivatives
ES402263A1 (es) Un metodo para sintetizar nuevos analogos de prostaglandi- na.
CH612179A5 (en) Process for the preparation of new prostaglandin analogues
FR2445337A1 (fr) Procede et composes intermediaires pour la preparation de derives de la prostaglandine
FR2372820A1 (fr) Procede de preparation de derives d'alcenyl-6 oxa-2 bicyclo (3-3-0) octanones-3, intermediaires pour la preparation de prostaglandines
SE7701666L (sv) Nya bicykliska laktonderivat for anvendning som mellan produkt vid syntes av prostaglandiner jemte sett for framstellning av nemnda laktonderivat
SE7509674L (sv) Forfarande for framstellning av 11beta-hydroxi-18-alkyl-ostranforeningar
GB1341204A (en) Process for the manufacture of triarylmethane compounds
SE7706083L (sv) Bicykliska laktondiolderivat jemte sett for deras framstellning
ES394667A1 (es) Procedimiento de preparacion de derivados del acido prosta-noico.
GB1498764A (en) Preparation of prostaglandin intermediates
ES441003A1 (es) Un procedimiento para preparar productos intermedios utiles en la sintesis de prosglandinas.
SE7611702L (sv) Sett att framstella nya cyklopentanonderivat och anvendning derav for syntes av prostaglandiner
JPS5283436A (en) Preparation of intermediates for synthesis of prostaglandin
JPS5242855A (en) Process for preparation of 7_(2-alkoxycarbonylcyclopentyl+)-5-heptenoi c acid
GB1396042A (en) Derivatives of 1-2-thienyl-2-amino-ethanol and their preparation
GB1482047A (en) Bicyclohexane derivatives for use in the synthesis of prostaglandins
GB1349048A (en) Esters and process for preparing same

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 7908126-1

Format of ref document f/p: F