SE7803860L - Forfarande for framstellning av 7-d-(-)-alfa-amino-alfa(p-hydroxifenylacetamido)desacetoxicefalosporansyra - Google Patents

Forfarande for framstellning av 7-d-(-)-alfa-amino-alfa(p-hydroxifenylacetamido)desacetoxicefalosporansyra

Info

Publication number
SE7803860L
SE7803860L SE7803860A SE7803860A SE7803860L SE 7803860 L SE7803860 L SE 7803860L SE 7803860 A SE7803860 A SE 7803860A SE 7803860 A SE7803860 A SE 7803860A SE 7803860 L SE7803860 L SE 7803860L
Authority
SE
Sweden
Prior art keywords
alfa
hydroxifenylacetamido
desacetoxic
amino
procedure
Prior art date
Application number
SE7803860A
Other languages
English (en)
Other versions
SE434840B (sv
Inventor
D Bouzard
A Weber
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE7803860L publication Critical patent/SE7803860L/sv
Publication of SE434840B publication Critical patent/SE434840B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SE7803860A 1974-06-05 1978-04-05 Forfarande for framstellning av 7-d-(-)-alfa-amino-alfa(p-hydroxifenylacetamido)desacetoxicefalosporansyra SE434840B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2484874A GB1476981A (en) 1974-06-05 1974-06-05 Substituted penicillanic acids

Publications (2)

Publication Number Publication Date
SE7803860L true SE7803860L (sv) 1978-04-05
SE434840B SE434840B (sv) 1984-08-20

Family

ID=10218206

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7506294A SE426171B (sv) 1974-06-05 1975-06-02 Forfarande for framstellning av d-(-)-alfa-amino-alfa-(p-acyloxifenyl) acetamidocefalosporansyror
SE7803860A SE434840B (sv) 1974-06-05 1978-04-05 Forfarande for framstellning av 7-d-(-)-alfa-amino-alfa(p-hydroxifenylacetamido)desacetoxicefalosporansyra

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7506294A SE426171B (sv) 1974-06-05 1975-06-02 Forfarande for framstellning av d-(-)-alfa-amino-alfa-(p-acyloxifenyl) acetamidocefalosporansyror

Country Status (25)

Country Link
US (1) US4012382A (sv)
JP (4) JPS6150955B2 (sv)
AR (2) AR210855A1 (sv)
AT (1) AT339480B (sv)
AU (1) AU496892B2 (sv)
BE (2) BE828686A (sv)
CA (1) CA1051799A (sv)
CH (1) CH617202A5 (sv)
CS (1) CS189709B2 (sv)
DD (3) DD127730A5 (sv)
DE (1) DE2524320C2 (sv)
DK (2) DK155943C (sv)
ES (2) ES438179A1 (sv)
FI (1) FI60867C (sv)
FR (2) FR2273546A1 (sv)
GB (1) GB1476981A (sv)
HU (3) HU174102B (sv)
IE (1) IE43052B1 (sv)
IL (2) IL47360A (sv)
IN (1) IN142267B (sv)
LU (1) LU72618A1 (sv)
SE (2) SE426171B (sv)
SU (3) SU828968A3 (sv)
YU (3) YU40121B (sv)
ZA (2) ZA752504B (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4286089A (en) * 1974-12-27 1981-08-25 Smithkline Corporation 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins
US3989694A (en) * 1974-12-27 1976-11-02 Smithkline Corporation 7-Acyl-3-(substituted triazolyl thiomethyl)cephalosporins
FI66005C (fi) * 1975-02-04 1984-08-10 Fujisawa Pharmaceutical Co Foerfarande foer framstaellning av antibakteriellt verkande 7-alfa alfa-disubstituerad-acetamido)-3-substituerad-3-cefe m--karboxylsyras syn-isomer
US4093723A (en) * 1976-05-19 1978-06-06 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
US4107440A (en) * 1975-12-15 1978-08-15 Smithkline Corporation Intermediates for preparing substituted phenylglycylcephalosporins
IL51651A0 (en) * 1976-03-19 1977-05-31 Merck Patent Gmbh Cephem derivatives and processes for their preparation
GB1532682A (en) 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
US4034092A (en) * 1976-05-03 1977-07-05 Smithkline Corporation 7-Acyl-3-(carboxyalkyl and carbamoylalkyl substituted oxadiazolylthiomethyl) cephalosporins
AU2550077A (en) * 1976-06-14 1978-11-30 Merck Patent Gmbh Penicillins and cephalosporins
JPS5346995A (en) * 1976-10-12 1978-04-27 Sangyo Kagaku Kenkyu Kyokai Antibacterial agents
US4160863A (en) 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
US4236002A (en) * 1977-12-23 1980-11-25 Yeda Research & Development Co., Ltd. Cephalosporin derivatives
DE2852067A1 (de) * 1978-11-29 1980-06-12 Schering Ag Verfahren zur herstellung von 5-mercapto-1,2,3-triazolen
DE2920939A1 (de) * 1979-05-21 1980-11-27 Schering Ag Verfahren zur herstellung von 5-mercapto-1,2,3-triazolen
JPS58122471U (ja) * 1982-02-15 1983-08-20 株式会社ほくさん クライオスタツトのスペ−サ−
JPS59152757U (ja) * 1983-03-31 1984-10-13 株式会社ほくさん クライオスタツトのスペ−サ
JPS6019776A (ja) * 1983-07-12 1985-01-31 Ube Ind Ltd 安定化された５―メルカプト―１，２，３―チアジアゾール類組成物
JPS6041271A (ja) * 1984-07-09 1985-03-04 Hitachi Ltd 超電導装置
GB9216759D0 (en) * 1992-08-07 1992-09-23 Finpael Spa Process for the production of 7-amino thiazolyl cephalosporins
US6550343B2 (en) * 2001-07-13 2003-04-22 Westinghouse Air Brake Technologies Corporation Method and apparatus for testing shear strength of rubber bonded to metal insert

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1461320A (fr) 1961-04-10 1966-02-25 Nat Res Dev Procédé de production de dérivés de désacétylation de la céphalosporine c
GB1082943A (en) * 1963-03-27 1967-09-13 Glaxo Lab Ltd Derivatives of 7-aminocephalosporanic acid
GB1082962A (en) * 1963-05-28 1967-09-13 Glaxo Lab Ltd Derivatives of 7-aminocephalosporanic acid
DE1445639B2 (de) 1963-11-19 1976-09-09 Ciba-Geigy Ag, Basel (Schweiz) Verfahren zur herstellung von desacetyl-7-aminocephalosporansaeure
FR1460131A (fr) * 1964-10-30 1966-06-17 Glaxo Lab Ltd Procédé de préparation de produits de dégradation de la céphalosporine c et de ses dérivés
US3453263A (en) * 1965-03-01 1969-07-01 American Home Prod Method of preparing penicillins
GB1241656A (en) * 1967-08-21 1971-08-04 Glaxo Lab Ltd Improvements in or relating to cephalosporin compounds
CY773A (en) * 1967-09-05 1975-03-01 Bristol Myers Co Antibacterial agents and a process for the preparation thereof
GB1277415A (en) * 1968-06-14 1972-06-14 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
US3579514A (en) * 1969-01-24 1971-05-18 Bristol Myers Co 7 - (alpha-(3 - guanyl-1-ureido)aryl-acetamido) cephalosporanic acids and derivatives thereof
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
GB1326531A (en) * 1969-08-26 1973-08-15 Glaxo Lab Ltd Cephalosporin compounds
US3753977A (en) * 1969-11-27 1973-08-21 Ciba Geigy Corp Process for the cleavage of esters of 7-amino-cephem-4-carboxylic acid compounds
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
GB1334382A (en) * 1970-03-26 1973-10-17 Glaxo Lab Ltd Antibiotics
US3701775A (en) * 1970-11-25 1972-10-31 Smith Kline French Lab Esters of mandeloylaminocephalosporanic acids
US3855213A (en) * 1971-02-18 1974-12-17 Smith Kline French Lab 3-heterocyclic thiomethyl-cephalosporins
US3867380A (en) * 1971-02-18 1975-02-18 Smithkline Corp 3-Heterocyclic thiomethylcephalosporins
IL38099A (en) * 1970-12-17 1976-01-30 Smith Kline French Lab 3-heterocyclyl thiomethylcephalosporins
GB1319173A (en) * 1971-06-17 1973-06-06 Fujisawa Pharmaceutical Co 7-acylated-3-substituted cephalosporin compounds
JPS5442997B2 (sv) * 1971-10-18 1979-12-17
JPS4868588A (sv) * 1971-12-22 1973-09-18
US3813388A (en) * 1972-01-31 1974-05-28 L Crast 7-(d-(alpha-amino-alpha-phenyl-,2-thienyl-and 3-thienyl-acetamido))-3-(s-(2-methyl-1,2,3-triazole-4-yl)thiomethyl)-3-cephem-4-carboxylic acids
CA1076560A (en) * 1972-06-14 1980-04-29 Smith Kline And French Canada Ltd. 3-heterocyclic thiomethylcephalosporins
US3868369A (en) * 1972-11-14 1975-02-25 Smithkline Corp 3-heterocyclicthiomethylcephalosporins
US3943129A (en) * 1972-11-14 1976-03-09 Smithkline Corporation 7-Amino-3-(1,3,4-thiadiazolinylthio-methyl) cephalosporins
US3953439A (en) * 1973-08-01 1976-04-27 Smithkline Corporation Substituted phenylglycylcephalosporins
US3931160A (en) * 1974-05-15 1976-01-06 Smithkline Corporation α-Amino-α-(acylamidophenyl)acetamidocephalosporins

Also Published As

Publication number Publication date
GB1476981A (en) 1977-06-16
SU828968A3 (ru) 1981-05-07
SE426171B (sv) 1982-12-13
ZA753387B (en) 1976-04-28
DK156272C (da) 1989-12-18
US4012382A (en) 1977-03-15
DD127730A5 (de) 1977-10-12
ZA752504B (en) 1976-03-31
JPS5111785A (sv) 1976-01-30
FR2296639B1 (sv) 1978-10-06
FR2273546A1 (fr) 1976-01-02
YU143775A (en) 1982-02-28
AR208111A1 (es) 1976-11-30
FI60867B (fi) 1981-12-31
HU172448B (hu) 1978-09-28
DK236275A (da) 1975-12-06
IE43052L (en) 1975-12-05
YU199881A (en) 1983-12-31
JPS6219160B2 (sv) 1987-04-27
IL47360A0 (en) 1975-11-25
FI751595A (sv) 1975-12-06
ES438179A1 (es) 1977-05-16
YU43130B (en) 1989-04-30
YU45103B (en) 1992-03-10
DD127731A5 (de) 1977-10-12
DK155943C (da) 1989-10-16
JPS6150955B2 (sv) 1986-11-06
JPS60259198A (ja) 1985-12-21
CS189709B2 (en) 1979-04-30
CH617202A5 (sv) 1980-05-14
DK155943B (da) 1989-06-05
YU199781A (en) 1983-12-31
ATA429375A (de) 1977-02-15
IN142267B (sv) 1977-06-18
BE829758A (fr) 1975-12-01
DE2524320C2 (de) 1985-01-24
CA1051799A (en) 1979-04-03
JPS6260079B2 (sv) 1987-12-14
JPS60260585A (ja) 1985-12-23
SU629880A3 (ru) 1978-10-25
FI60867C (fi) 1982-04-13
IE43052B1 (en) 1980-12-17
AU8152975A (en) 1976-12-02
JPS60166688A (ja) 1985-08-29
YU40121B (en) 1985-08-31
ES454964A1 (es) 1978-01-16
SE7506294L (sv) 1975-12-08
HU173040B (hu) 1979-02-28
AR210855A1 (es) 1977-09-30
IL53407A0 (en) 1978-01-31
HU174102B (hu) 1979-11-28
SE434840B (sv) 1984-08-20
DE2524320A1 (de) 1975-12-18
LU72618A1 (sv) 1976-03-17
AT339480B (de) 1977-10-25
DK559588D0 (da) 1988-10-06
DK559588A (da) 1988-10-06
DD122094A5 (sv) 1976-09-12
FR2296639A1 (fr) 1976-07-30
BE828686A (fr) 1975-09-01
SU654171A3 (ru) 1979-03-25
IL47360A (en) 1978-12-17
AU496892B2 (en) 1978-11-09
DK156272B (da) 1989-07-24

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