SE7501317L - - Google Patents
Info
- Publication number
- SE7501317L SE7501317L SE7501317A SE7501317A SE7501317L SE 7501317 L SE7501317 L SE 7501317L SE 7501317 A SE7501317 A SE 7501317A SE 7501317 A SE7501317 A SE 7501317A SE 7501317 L SE7501317 L SE 7501317L
- Authority
- SE
- Sweden
- Prior art keywords
- protecting group
- group
- ceph
- feb
- compounds
- Prior art date
Links
- 125000006239 protecting group Chemical group 0.000 abstract 3
- FZEVMBJWXHDLDB-ZCFIWIBFSA-N (6r)-5-thia-1-azabicyclo[4.2.0]oct-2-en-8-one Chemical class S1CC=CN2C(=O)C[C@H]21 FZEVMBJWXHDLDB-ZCFIWIBFSA-N 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C313/02—Sulfinic acids; Derivatives thereof
- C07C313/04—Sulfinic acids; Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH269374A CH601310A5 (en) | 1974-02-26 | 1974-02-26 | 7-Amino-3-hydroxy-2(or 3)-cephem-4-carboxylic acid derivs prepn |
| CH776674A CH610584A5 (en) | 1974-02-26 | 1974-06-05 | Process for the preparation of 2-(3-amino-2-oxo-4-sulphonylthio-1- azetidinyl)-3-methylenebutyric acid derivatives |
| CH1100074 | 1974-08-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7501317L true SE7501317L (enrdf_load_stackoverflow) | 1975-08-27 |
| SE431652B SE431652B (sv) | 1984-02-20 |
Family
ID=27173851
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7501317A SE431652B (sv) | 1974-02-26 | 1975-02-06 | Forfarande for framstellning av 7beta-amino-3cefem-3ol-4-karboxylsyraderivat |
| SE7807810A SE438854B (sv) | 1974-02-26 | 1978-07-13 | 3-metylensmorsyraderivat till anvendning sasom mellanprodukt vid syntesen av 3-cefemforeningar |
| SE7807811A SE438855B (sv) | 1974-02-26 | 1978-07-13 | 3-hydroxikrotonsyraderivat till anvendning sasom mellanprodukt vid syntesen av 3-cefemforeningar |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7807810A SE438854B (sv) | 1974-02-26 | 1978-07-13 | 3-metylensmorsyraderivat till anvendning sasom mellanprodukt vid syntesen av 3-cefemforeningar |
| SE7807811A SE438855B (sv) | 1974-02-26 | 1978-07-13 | 3-hydroxikrotonsyraderivat till anvendning sasom mellanprodukt vid syntesen av 3-cefemforeningar |
Country Status (21)
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1044247B (it) * | 1974-08-02 | 1980-03-20 | Farmaceutici Italia | Intermedi per la sintesi di derivati b lattamici e procedimento per la loro preparazone |
| CA1136132A (en) * | 1975-02-17 | 1982-11-23 | Teruji Tsuji | Cyclization to form cephem ring and intermediates therefor |
| JPS5198265A (enrdf_load_stackoverflow) * | 1975-02-17 | 1976-08-30 | ||
| AT342197B (de) * | 1975-02-20 | 1978-03-28 | Ciba Geigy Ag | Neues verfahren zur herstellung von 3-cephemverbindungen |
| US4029645A (en) * | 1975-11-17 | 1977-06-14 | E. R. Squibb & Sons, Inc. | Mercury intermediates useful in the preparation of 2-alkoxy cephalosporins |
| US4301279A (en) | 1979-02-23 | 1981-11-17 | Ciba-Geigy Corporation | Process for the production of 3-hydroxy compounds |
| JPH0639474B2 (ja) * | 1983-03-04 | 1994-05-25 | 大塚化学株式会社 | セファロスポリン化合物の製造法 |
| JPS59228854A (ja) * | 1983-06-08 | 1984-12-22 | 真井 康博 | 薬液収納兼即効注出器 |
| JPS60115562A (ja) * | 1983-11-28 | 1985-06-22 | Otsuka Chem Co Ltd | アゼチジノン誘導体の製造法 |
| GB2152497B (en) * | 1983-11-28 | 1987-08-05 | Otsuka Kagaku Kk | Process for the preparation of azetidinone derivatives |
| JPS60126263A (ja) * | 1983-12-12 | 1985-07-05 | Otsuka Chem Co Ltd | アゼチジノン誘導体の製造法 |
| JPS60237061A (ja) * | 1984-05-08 | 1985-11-25 | Otsuka Chem Co Ltd | アゼチジノン誘導体の製造法 |
| JPS61178961A (ja) * | 1985-02-01 | 1986-08-11 | Otsuka Chem Co Ltd | アゼチジノン誘導体の製造法 |
| DE3725375A1 (de) * | 1987-07-31 | 1989-02-09 | Bayer Ag | Stabile oxapenem-3-carbonsaeuren |
| JP3195959B2 (ja) * | 1991-03-13 | 2001-08-06 | 大塚化学株式会社 | ３−ヒドロキシセフェム誘導体の製造法 |
| JP2006507289A (ja) * | 2002-11-01 | 2006-03-02 | オーキッド ケミカルズ アンド ファーマシューティカルズ リミテッド | 改良されたクロロメチルセフェム誘導体調製方法 |
| RS56212B1 (sr) | 2011-12-20 | 2017-11-30 | Riboscience Llc | 2',4'-difluoro-2'-metilom supstituisani nukleozidni derivati kao inhibitori replikacije rna hcv-a |
| CN108409820A (zh) | 2011-12-20 | 2018-08-17 | 里博科学有限责任公司 | 作为hcv rna复制抑制剂的4′-叠氮基，3′-氟取代的核苷衍生物 |
| KR20160039154A (ko) | 2013-05-16 | 2016-04-08 | 리보사이언스 엘엘씨 | 4''-아자이도-3''-데옥시-3''-플루오로 치환된 뉴클레오시드 유도체 |
| MY186547A (en) | 2013-05-16 | 2021-07-26 | Riboscience Llc | 4?-fluoro-2?-methyl substituted nucleoside derivatives |
| US20180200280A1 (en) | 2013-05-16 | 2018-07-19 | Riboscience Llc | 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication |
| JP7299897B2 (ja) | 2017-09-21 | 2023-06-28 | リボサイエンス リミティド ライアビリティ カンパニー | Ｈｃｖのｒｎａ複製阻害剤としての４’－フルオロ－２’－メチル置換ヌクレオシド誘導体 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2230372A1 (de) * | 1972-06-21 | 1973-01-11 | Fujisawa Pharmaceutical Co | Verfahren zur herstellung von oxidierten penam-derivaten |
| AR206201A1 (es) * | 1972-06-29 | 1976-07-07 | Ciba Geigy Ag | Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos |
| SE428022B (sv) * | 1972-06-29 | 1983-05-30 | Ciba Geigy Ag | 7beta-amino-cefam-3-on-4-karboxylsyraforeningar till anvendning for framstellning av cefalosporinderivat |
-
1974
- 1974-02-24 AU AU78498/75A patent/AU498131B2/en not_active Expired
-
1975
- 1975-02-06 SE SE7501317A patent/SE431652B/xx not_active IP Right Cessation
- 1975-02-12 NZ NZ176623A patent/NZ176623A/xx unknown
- 1975-02-13 AT AT108275A patent/AT337362B/de not_active IP Right Cessation
- 1975-02-14 DE DE19752506330 patent/DE2506330A1/de not_active Ceased
- 1975-02-21 FI FI750503A patent/FI66389C/fi not_active IP Right Cessation
- 1975-02-24 GB GB7625/75A patent/GB1503581A/en not_active Expired
- 1975-02-24 FR FR7505654A patent/FR2261761B1/fr not_active Expired
- 1975-02-24 BG BG029066A patent/BG26201A3/xx unknown
- 1975-02-24 NO NO750625A patent/NO750625L/no unknown
- 1975-02-24 DD DD184382A patent/DD117074A5/xx unknown
- 1975-02-25 IL IL46699A patent/IL46699A/en unknown
- 1975-02-25 IE IE401/75A patent/IE40695B1/xx unknown
- 1975-02-25 HU HU75CI1550A patent/HU175212B/hu unknown
- 1975-02-25 BE BE153680A patent/BE825919A/xx not_active IP Right Cessation
- 1975-02-25 DK DK73475*#A patent/DK73475A/da not_active Application Discontinuation
- 1975-02-25 CA CA220,745A patent/CA1059988A/en not_active Expired
- 1975-02-26 AR AR257777A patent/AR208538A1/es active
- 1975-02-26 JP JP50023775A patent/JPS625919B2/ja not_active Expired
- 1975-02-26 ES ES435110A patent/ES435110A1/es not_active Expired
- 1975-02-26 NL NL7502292A patent/NL7502292A/xx not_active Application Discontinuation
-
1976
- 1976-11-02 ES ES452915A patent/ES452915A1/es not_active Expired
-
1978
- 1978-01-16 AT AT28178A patent/AT350068B/de not_active IP Right Cessation
- 1978-07-13 SE SE7807810A patent/SE438854B/sv not_active IP Right Cessation
- 1978-07-13 SE SE7807811A patent/SE438855B/sv not_active IP Right Cessation
- 1978-08-07 DK DK348678A patent/DK348678A/da not_active Application Discontinuation
-
1979
- 1979-04-06 CA CA325,019A patent/CA1080713A/en not_active Expired
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE7501317L (enrdf_load_stackoverflow) | ||
| GB1432576A (en) | Substituted phenylacetic acids | |
| GB1418822A (en) | Imidazo-and pyrimido-2,1-b-quinazolin-2-ones and a process for the preparation thereof | |
| GB1451999A (en) | Quinone derivatives | |
| GB1480772A (en) | Antibiotic derivatives | |
| GB1301973A (enrdf_load_stackoverflow) | ||
| IE44069L (en) | Noroxymorphones | |
| GB1409648A (en) | Substituted pyrrolidinemethanol compounds and pharmaceutical compositions thereof | |
| GB1503640A (en) | Process for the manufacture of 3-substitutedhydrody-crotonic and isocrotonic acid derivatives | |
| GB1325770A (en) | Pyrimidopyridazine derivatives | |
| GB1242160A (en) | Isoquinolines | |
| GB1529403A (en) | Isoxazole derivative | |
| GB1352245A (en) | Azabicyclo-3.3.1-nonan-3-ol ester derivatives | |
| GB1509454A (en) | 2-amino-tetralins | |
| JPS51136676A (en) | Process for preparation of carbostyril derivatives | |
| SE7403907L (enrdf_load_stackoverflow) | ||
| GB1378964A (en) | Pyridine derivatives | |
| JPS543090A (en) | Novel derivative of cephalosporin compound and its preparation | |
| IE56365B1 (en) | Treatment of migraine with n-alkyl-piperidinyl benzoate derivatives | |
| GB1321361A (en) | Preparation of pyrimidylmethyl-pyridinium derivatives | |
| IE34081L (en) | Butanolamines | |
| GB1471371A (en) | Cyclopenteno-b-pyridine derivative | |
| GB1367678A (en) | Substituted phenyl aminoethanols | |
| GB1432387A (en) | 2-alkoxy-4-m-dithian-2-yl-cyclopenta-b-furans | |
| GB1420728A (en) | Cephalosporins |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
Ref document number: 7501317-7 Effective date: 19910117 Format of ref document f/p: F |