SE527896C2 - Optisk testanordning för biologiska prover, samt en microarray till anordningen och metoden för dess användning - Google Patents
Optisk testanordning för biologiska prover, samt en microarray till anordningen och metoden för dess användningInfo
- Publication number
- SE527896C2 SE527896C2 SE0301470A SE0301470A SE527896C2 SE 527896 C2 SE527896 C2 SE 527896C2 SE 0301470 A SE0301470 A SE 0301470A SE 0301470 A SE0301470 A SE 0301470A SE 527896 C2 SE527896 C2 SE 527896C2
- Authority
- SE
- Sweden
- Prior art keywords
- support plate
- grooves
- microarray
- polymeric
- focal length
- Prior art date
Links
- 238000002493 microarray Methods 0.000 title claims abstract description 53
- 230000003287 optical effect Effects 0.000 title claims abstract description 46
- 238000000034 method Methods 0.000 title claims description 6
- 239000012472 biological sample Substances 0.000 title 1
- 238000002310 reflectometry Methods 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 7
- 239000000049 pigment Substances 0.000 claims description 3
- 201000008009 Early infantile epileptic encephalopathy Diseases 0.000 claims 1
- 230000006978 adaptation Effects 0.000 claims 1
- 210000000436 anus Anatomy 0.000 claims 1
- 208000013257 developmental and epileptic encephalopathy Diseases 0.000 claims 1
- 238000003556 assay Methods 0.000 abstract description 2
- 230000023077 detection of light stimulus Effects 0.000 abstract description 2
- 239000000758 substrate Substances 0.000 description 12
- 229920000642 polymer Polymers 0.000 description 7
- 230000008901 benefit Effects 0.000 description 5
- 239000011521 glass Substances 0.000 description 5
- 239000000523 sample Substances 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 238000005520 cutting process Methods 0.000 description 3
- 239000003989 dielectric material Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 239000004065 semiconductor Substances 0.000 description 3
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000027455 binding Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 241000976924 Inca Species 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003667 anti-reflective effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000001312 dry etching Methods 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000609 electron-beam lithography Methods 0.000 description 1
- 238000004049 embossing Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000001459 lithography Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 238000012775 microarray technology Methods 0.000 description 1
- 230000009871 nonspecific binding Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 229920002120 photoresistant polymer Polymers 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 238000000159 protein binding assay Methods 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 125000005372 silanol group Chemical group 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 238000001039 wet etching Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5088—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Optical Measuring Cells (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0301470A SE527896C2 (sv) | 2003-05-20 | 2003-05-20 | Optisk testanordning för biologiska prover, samt en microarray till anordningen och metoden för dess användning |
| EP04733713A EP1625396A1 (en) | 2003-05-20 | 2004-05-18 | Polymeric microarray support, method of forming microfeatures and on optical assay arrangement |
| BRPI0410782A BRPI0410782B1 (pt) | 2003-05-20 | 2004-05-18 | suporte de micro arranjo polimérico, método de formação de micro características e uma disposição de ensaio ótico |
| JP2006532195A JP2007500358A (ja) | 2003-05-20 | 2004-05-18 | 高分子のマイクロアレイ支持体、微細特徴の形成方法、及び、光学分析装置 |
| PCT/SE2004/000761 WO2004104585A1 (en) | 2003-05-20 | 2004-05-18 | Polymeric microarray support, method of forming microfeatures and on optical assay arrangement |
| CNB2004800135554A CN100449314C (zh) | 2003-05-20 | 2004-05-18 | 聚合物微阵列支持体、形成微特征的方法及一种光学检定装置 |
| AU2004241519A AU2004241519B2 (en) | 2003-05-20 | 2004-05-18 | Polymeric microarray support, method of forming microfeatures and on optical assay arrangement |
| US10/556,961 US8000001B2 (en) | 2003-05-20 | 2004-05-18 | Method of forming polymeric microarray support |
| US13/179,143 US20110306519A1 (en) | 2003-05-20 | 2011-07-08 | Method of forming polymeric microarray support |
| JP2011197011A JP2011242411A (ja) | 2003-05-20 | 2011-09-09 | マイクロアレイ支持体とプローブ分子との組み合わせおよびマイクロアレイ支持体形成方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0301470A SE527896C2 (sv) | 2003-05-20 | 2003-05-20 | Optisk testanordning för biologiska prover, samt en microarray till anordningen och metoden för dess användning |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE0301470D0 SE0301470D0 (sv) | 2003-05-20 |
| SE0301470L SE0301470L (sv) | 2004-11-21 |
| SE527896C2 true SE527896C2 (sv) | 2006-07-04 |
Family
ID=20291357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0301470A SE527896C2 (sv) | 2003-05-20 | 2003-05-20 | Optisk testanordning för biologiska prover, samt en microarray till anordningen och metoden för dess användning |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8000001B2 (enExample) |
| EP (1) | EP1625396A1 (enExample) |
| JP (2) | JP2007500358A (enExample) |
| CN (1) | CN100449314C (enExample) |
| AU (1) | AU2004241519B2 (enExample) |
| BR (1) | BRPI0410782B1 (enExample) |
| SE (1) | SE527896C2 (enExample) |
| WO (1) | WO2004104585A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7814456B2 (en) * | 2004-11-22 | 2010-10-12 | Tela Innovations, Inc. | Method and system for topography-aware reticle enhancement |
| WO2006075965A1 (en) | 2005-01-17 | 2006-07-20 | Gyros Patent Ab | A method for detecting an at least bivalent analyte using two affinity reactants |
| SE529254C2 (sv) * | 2005-06-17 | 2007-06-12 | Aamic Ab | Optiskt testsystem |
| WO2007072418A2 (en) * | 2005-12-22 | 2007-06-28 | Koninklijke Philips Electronics N.V. | Increasing energy density in sub-wavelength wire-grids |
| CN102939526A (zh) * | 2010-06-02 | 2013-02-20 | 皇家飞利浦电子股份有限公司 | 具有光折射结构的样品载体 |
| US20170274374A1 (en) * | 2016-03-28 | 2017-09-28 | Ilumina, Inc. | Multi-plane microarrays |
| GB201610426D0 (en) | 2016-06-15 | 2016-07-27 | Q-Linea Ab | Sample holder for image based analysis of samples |
| KR102459968B1 (ko) * | 2022-01-21 | 2022-10-27 | 주식회사 큐어팜텍 | 기능성 약물이 함유된 생분해성 수지 제조방법 및 이에 의해 제조된 생분해성 수지 |
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| JPS58102157A (ja) * | 1981-12-15 | 1983-06-17 | Olympus Optical Co Ltd | 粒子凝集パタ−ン判定方法 |
| US5354695A (en) * | 1992-04-08 | 1994-10-11 | Leedy Glenn J | Membrane dielectric isolation IC fabrication |
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US6143576A (en) * | 1992-05-21 | 2000-11-07 | Biosite Diagnostics, Inc. | Non-porous diagnostic devices for the controlled movement of reagents |
| US6905882B2 (en) * | 1992-05-21 | 2005-06-14 | Biosite, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US6767510B1 (en) * | 1992-05-21 | 2004-07-27 | Biosite, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| US6156270A (en) * | 1992-05-21 | 2000-12-05 | Biosite Diagnostics, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
| GB9314991D0 (en) * | 1993-07-20 | 1993-09-01 | Sandoz Ltd | Mechanical device |
| JP3029524B2 (ja) | 1993-10-06 | 2000-04-04 | シャープ株式会社 | 回折格子の製造方法 |
| US5575962A (en) | 1994-12-02 | 1996-11-19 | Lucent Technologies Inc. | Method for fabricating optical quality molds with precision microfeatures |
| EP2259070A3 (en) * | 1995-07-31 | 2011-03-30 | Precision System Science Co., Ltd. | Container |
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| US20020177144A1 (en) * | 1997-12-30 | 2002-11-28 | Jose Remacle | Detection and/or quantification method of a target molecule by a binding with a capture molecule fixed on the surface of a disc |
| DE19919092A1 (de) * | 1999-04-27 | 2000-11-02 | Zeiss Carl Jena Gmbh | Anordnung zur optischen Auswertung eines Gegenstandsarrays |
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| JP3551860B2 (ja) | 1999-10-05 | 2004-08-11 | 株式会社日立製作所 | Dna検査方法及びdna検査装置 |
| CN1263161A (zh) * | 1999-12-29 | 2000-08-16 | 中国科学院上海冶金研究所 | 一种cDNA微阵列芯片、制作方法及其应用 |
| JP2001208974A (ja) * | 2000-01-24 | 2001-08-03 | Nikon Corp | 共焦点型顕微鏡及び一括照明型顕微鏡 |
| CA2395318C (en) * | 2000-02-16 | 2007-05-01 | Wisconsin Alumni Research Foundation | Method and apparatus for detection of microscopic pathogens |
| JP2001238674A (ja) * | 2000-02-29 | 2001-09-04 | Nikon Corp | Dnaアレイ、dnaアレイ読み取り装置、及びdnaアレイ製造装置 |
| US20020012953A1 (en) * | 2000-03-14 | 2002-01-31 | Jauho Eva Irene Stenbaek | Methods for separation and isolation of subpopulations of cells in biological samples |
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-
2003
- 2003-05-20 SE SE0301470A patent/SE527896C2/sv not_active IP Right Cessation
-
2004
- 2004-05-18 CN CNB2004800135554A patent/CN100449314C/zh not_active Expired - Fee Related
- 2004-05-18 US US10/556,961 patent/US8000001B2/en not_active Expired - Fee Related
- 2004-05-18 BR BRPI0410782A patent/BRPI0410782B1/pt not_active IP Right Cessation
- 2004-05-18 AU AU2004241519A patent/AU2004241519B2/en not_active Ceased
- 2004-05-18 WO PCT/SE2004/000761 patent/WO2004104585A1/en not_active Ceased
- 2004-05-18 JP JP2006532195A patent/JP2007500358A/ja active Pending
- 2004-05-18 EP EP04733713A patent/EP1625396A1/en not_active Withdrawn
-
2011
- 2011-07-08 US US13/179,143 patent/US20110306519A1/en not_active Abandoned
- 2011-09-09 JP JP2011197011A patent/JP2011242411A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004241519B2 (en) | 2009-05-07 |
| US20070065935A1 (en) | 2007-03-22 |
| JP2011242411A (ja) | 2011-12-01 |
| CN100449314C (zh) | 2009-01-07 |
| US8000001B2 (en) | 2011-08-16 |
| JP2007500358A (ja) | 2007-01-11 |
| AU2004241519A1 (en) | 2004-12-02 |
| EP1625396A1 (en) | 2006-02-15 |
| BRPI0410782B1 (pt) | 2016-03-01 |
| CN1791798A (zh) | 2006-06-21 |
| WO2004104585A1 (en) | 2004-12-02 |
| US20110306519A1 (en) | 2011-12-15 |
| BRPI0410782A (pt) | 2006-06-20 |
| SE0301470D0 (sv) | 2003-05-20 |
| SE0301470L (sv) | 2004-11-21 |
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| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |