SE465367B - Heterocykliska foereningar och deras framstaellning och farmaceutiska formuleringar - Google Patents

Heterocykliska foereningar och deras framstaellning och farmaceutiska formuleringar

Info

Publication number
SE465367B
SE465367B SE8603517A SE8603517A SE465367B SE 465367 B SE465367 B SE 465367B SE 8603517 A SE8603517 A SE 8603517A SE 8603517 A SE8603517 A SE 8603517A SE 465367 B SE465367 B SE 465367B
Authority
SE
Sweden
Prior art keywords
methyl
alkyl
phenyl
group
formula
Prior art date
Application number
SE8603517A
Other languages
English (en)
Swedish (sv)
Other versions
SE8603517D0 (sv
SE8603517L (sv
Inventor
C Semeraro
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT21958/85A external-priority patent/IT1201455B/it
Priority claimed from IT19480/86A external-priority patent/IT1204458B/it
Application filed by Glaxo Spa filed Critical Glaxo Spa
Publication of SE8603517D0 publication Critical patent/SE8603517D0/xx
Publication of SE8603517L publication Critical patent/SE8603517L/xx
Publication of SE465367B publication Critical patent/SE465367B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE8603517A 1985-08-21 1986-08-20 Heterocykliska foereningar och deras framstaellning och farmaceutiska formuleringar SE465367B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21958/85A IT1201455B (it) 1985-08-21 1985-08-21 Derivati piridinici sostituiti
IT19480/86A IT1204458B (it) 1986-02-20 1986-02-20 Derivati eterociclici

Publications (3)

Publication Number Publication Date
SE8603517D0 SE8603517D0 (sv) 1986-08-20
SE8603517L SE8603517L (sv) 1987-02-22
SE465367B true SE465367B (sv) 1991-09-02

Family

ID=26327180

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8603517A SE465367B (sv) 1985-08-21 1986-08-20 Heterocykliska foereningar och deras framstaellning och farmaceutiska formuleringar

Country Status (18)

Country Link
US (1) US5162345A (ja)
JP (1) JPH0696552B2 (ja)
AT (1) AT394043B (ja)
AU (1) AU588352B2 (ja)
BE (1) BE905297A (ja)
CA (1) CA1337295C (ja)
CH (1) CH669788A5 (ja)
CY (1) CY1554A (ja)
DE (1) DE3628215C2 (ja)
DK (1) DK397686A (ja)
ES (1) ES2001104A6 (ja)
FR (1) FR2586417B1 (ja)
GB (1) GB2181127B (ja)
IE (1) IE59632B1 (ja)
NL (1) NL192385C (ja)
NZ (1) NZ217282A (ja)
SE (1) SE465367B (ja)
SG (1) SG40890G (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405833D0 (en) * 1994-03-24 1994-05-11 Pfizer Ltd Separation of the enantiomers of amlodipine
AU761467B2 (en) * 1998-06-09 2003-06-05 Ajinomoto Co., Inc. Novel enzyme-treated protein-containing food, and methods for producing the same
FR2892412B1 (fr) * 2005-10-26 2008-05-16 Galderma Res & Dev Composes biaromatiques modulateurs des ppars

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455945A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines
DE2228363A1 (de) * 1972-06-10 1974-01-03 Bayer Ag 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
DE2740080A1 (de) * 1977-09-06 1979-03-15 Bayer Ag 2-alkylenaminodihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2753946A1 (de) * 1977-12-03 1979-06-13 Bayer Ag 1-n-aryl-1,4-dihydropyridine und ihre verwendung als arzneimittel
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
CS228917B2 (en) * 1981-03-14 1984-05-14 Pfizer Method of preparing substituted derivatives of 1,4-dihydropyridine
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
AU561213B2 (en) * 1983-06-02 1987-04-30 Teijin Limited 1, 4-dihydropyridine derivative
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
IT1204462B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
DE3607821A1 (de) * 1986-03-08 1987-09-10 Bayer Ag Aminoester-dihydropyridine, verfahren zur herstellung und ihre verwendung
US4814455A (en) * 1986-04-16 1989-03-21 Bristol-Myers Company Dihydro-3,5-dicarboxylates

Also Published As

Publication number Publication date
DE3628215C2 (de) 1996-09-19
SG40890G (en) 1990-08-03
GB2181127A (en) 1987-04-15
NL8602117A (nl) 1987-03-16
IE59632B1 (en) 1994-03-09
CH669788A5 (ja) 1989-04-14
IE862227L (en) 1987-02-21
GB2181127B (en) 1989-08-02
CA1337295C (en) 1995-10-10
NZ217282A (en) 1989-01-27
SE8603517D0 (sv) 1986-08-20
JPS6296467A (ja) 1987-05-02
AU588352B2 (en) 1989-09-14
DK397686D0 (da) 1986-08-20
SE8603517L (sv) 1987-02-22
DE3628215A1 (de) 1987-02-26
US5162345A (en) 1992-11-10
FR2586417B1 (fr) 1991-08-30
NL192385B (nl) 1997-03-03
JPH0696552B2 (ja) 1994-11-30
BE905297A (fr) 1987-02-20
ES2001104A6 (es) 1988-04-16
GB8620217D0 (en) 1986-10-01
FR2586417A1 (fr) 1987-02-27
NL192385C (nl) 1997-07-04
CY1554A (en) 1991-03-22
DK397686A (da) 1987-02-22
AU6166886A (en) 1987-02-26
AT394043B (de) 1992-01-27
ATA223986A (de) 1991-07-15

Similar Documents

Publication Publication Date Title
US6001836A (en) Dihydropyridine NPY antagonists: cyanoguanidine derivatives
HU187868B (en) Process for producing dihydropyridine derivatives
CZ219895A3 (en) The use of substituted derivatives of 4-phenyl-6-aminonicotinic acid as medicaments
EP0097821B1 (en) Dihydropyridines with an antagonistic activity to calcium, process for their preparation, and pharmaceutical compositions containing them
US6057332A (en) Substituted 1,4-dihydropyrimidine-5-carboxylate compounds, their preparation and uses
EP0215250B1 (en) 2-substituted-1,4-dihydropyridines, method for their preparation and pharmaceutical compositions containing them
SE465367B (sv) Heterocykliska foereningar och deras framstaellning och farmaceutiska formuleringar
CA1208639A (en) 1,4-dihydropropyridine derivatives, in optically active or in racemate form and their production and pharmaceutical compositions
CZ217495A3 (en) 2,3-cyclically condensed 1,4-dihydropyridines, process of their preparation, medicaments in which said substances are comprised and their use
EP0245919B1 (en) 1,4-dihydropyridine derivatives
EP0245918B1 (en) 1,4-dihydropyridine derivatives
US4491582A (en) N-(substituted piperazino)-1,4-dihydropyridine-3,5-carboxylic acid
CA1323876C (en) Dihydropyridine derivatives and pharmaceutical composition thereof
KR950011410B1 (ko) 헤테로사이클릭 화합물의 제조방법
EP0238211B1 (en) Dihydropyridines, process for their preparation and their use as medicaments
JPH0240383A (ja) １，４−ジヒドロピリジン誘導体
SK158095A3 (en) Application of 1,2-bridged 1,4-dihydropyridines, 1,2-bridged 1,4-dihydropyridines, manufacturing process thereof and pharmaceutical compositions containing them
EP0242950B1 (en) Dihydropyridines, process for their preparation and their use as therapeutics
RU1816282C (ru) Способ получени производных 2-аминоалкилтиометил-1,4-дигидропиридина или их энантиомеров
NO174419B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser
HU198907B (en) Process for producing dihydropyridine derivatives and pharmaceutical compositions containing them as active components
US5652251A (en) 6-amino-1,4-dihydropyridine compounds as medicaments for treatment of the central nervous system, and processes for their preparation
EP0479665A2 (en) 1,4-Dihydropyridine derivatives, method for preparing the same and use thereof
古林隆司 et al. Novel 2-Amino-1, 4-dihydropyridine Calcium Antagonists. II. Synthesis and Antihypertensive Effects of 2-Amino-1, 4-dihydropyridine Derivatives Having N, N-Dialkylaminoalkoxycarbonyl Groups at 3-and/or 5-Position.

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8603517-7

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8603517-7

Format of ref document f/p: F