SE463074B - Anvaendning av aromatashaemmare och antiandrogener foer framstaellning av laekemedel foer profylax och terapi av benign prostatahyperplasi - Google Patents

Anvaendning av aromatashaemmare och antiandrogener foer framstaellning av laekemedel foer profylax och terapi av benign prostatahyperplasi

Info

Publication number
SE463074B
SE463074B SE8104624A SE8104624A SE463074B SE 463074 B SE463074 B SE 463074B SE 8104624 A SE8104624 A SE 8104624A SE 8104624 A SE8104624 A SE 8104624A SE 463074 B SE463074 B SE 463074B
Authority
SE
Sweden
Prior art keywords
manufacture
antiandrogen
aromatase inhibitor
testolactone
carbon atoms
Prior art date
Application number
SE8104624A
Other languages
English (en)
Swedish (sv)
Other versions
SE8104624L (sv
Inventor
H-U Schweikert
U Tunn
T Senge
F Neumann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of SE8104624L publication Critical patent/SE8104624L/xx
Publication of SE463074B publication Critical patent/SE463074B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE8104624A 1981-05-22 1981-07-31 Anvaendning av aromatashaemmare och antiandrogener foer framstaellning av laekemedel foer profylax och terapi av benign prostatahyperplasi SE463074B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813121152 DE3121152A1 (de) 1981-05-22 1981-05-22 "verwendung der kombination eines aromatase-hemmers mit einem antiandrogen zur prophylaxe und therapie der prostatahyperplasie"

Publications (2)

Publication Number Publication Date
SE8104624L SE8104624L (sv) 1982-11-23
SE463074B true SE463074B (sv) 1990-10-08

Family

ID=6133382

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8104624A SE463074B (sv) 1981-05-22 1981-07-31 Anvaendning av aromatashaemmare och antiandrogener foer framstaellning av laekemedel foer profylax och terapi av benign prostatahyperplasi

Country Status (15)

Country Link
US (1) US4598072A (de)
JP (1) JPS57193412A (de)
AU (1) AU563785B2 (de)
BE (1) BE890522A (de)
CA (1) CA1186998A (de)
CH (1) CH648211A5 (de)
DE (1) DE3121152A1 (de)
DK (1) DK354881A (de)
FR (1) FR2506158B1 (de)
GB (1) GB2102287B (de)
IT (1) IT1139175B (de)
LU (1) LU83545A1 (de)
NL (1) NL8103875A (de)
SE (1) SE463074B (de)
ZA (1) ZA823501B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3607651A1 (de) * 1986-03-06 1987-09-10 Schering Ag Kombination von aromatasehemmer und testosteron-5(alpha)-reduktase-hemmer
US4895715A (en) * 1988-04-14 1990-01-23 Schering Corporation Method of treating gynecomastia
US5364847A (en) * 1989-03-10 1994-11-15 Endorecherche Inhibitors of sex steroid biosynthesis and methods for their production and use
US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
US5595985A (en) 1989-03-10 1997-01-21 Endorecherche Inc. Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia
WO1991000733A1 (en) * 1989-07-07 1991-01-24 Endorecherche Inc. Method of treatment of androgen-related diseases
JP3332377B2 (ja) * 1989-07-07 2002-10-07 アンドルシェルシュ・インコーポレイテッド 良性前立腺過形成の予防および／または治療のための組合せ療法
DE4001060A1 (de) * 1990-01-16 1991-07-18 Kanoldt Arzneimittel Gmbh Verwendung einer ungesaettigten fettsaeure oder ihrer derivate in der human- und veterinaermedizin und zur herstellung einer arzneimittelzubereitung
CZ286894A3 (en) * 1992-05-21 1995-09-13 Endorecherche Inc Pharmaceutical preparation
GB2278054A (en) * 1993-05-18 1994-11-23 Zeneca Ltd Compounds for the treatment of urinary incontinence
WO1999046279A2 (en) 1998-03-11 1999-09-16 Endorecherche, Inc. INHIBITORS OF TYPE 5 AND TYPE 3 17β-HYDROXYSTEROID DEHYDROGENASE AND METHODS FOR THEIR USE
DE19825591A1 (de) * 1998-06-09 1999-12-23 Jenapharm Gmbh Pharmazeutische Kombinationen zum Ausgleich eines Testosteron-Defizits beim Mann mit gleichzeitigem Schutz der Prostata
GB9930839D0 (en) * 1999-12-30 2000-02-16 Pharmacia & Upjohn Spa Process for treating gynecomastia
GB0012293D0 (en) * 2000-05-23 2000-07-12 Astrazeneca Ab Pharmaceutical combination
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US7001911B2 (en) * 2000-06-28 2006-02-21 Bristol-Myers Squibb Company Fused cyclic modulators of nuclear hormone receptor function
EP1299094A2 (de) * 2000-06-28 2003-04-09 Bristol-Myers Squibb Company Selektive androgenrezeptormodulatoren und methoden zu deren identifizierung, entwurf und verwendung
WO2002002112A1 (en) * 2000-07-05 2002-01-10 Astrazeneca Ab Pharmaceutical combination of an anti-androgen and anastrozole for providing an antiandrogenic effect and aromatase inhibition
WO2002002113A1 (en) * 2000-07-05 2002-01-10 Astrazeneca Ab Pharmaceutical combination of an anti-androgen and letrozole for providing an anit-androgenic effect and aromatase inhibition
GB0016426D0 (en) * 2000-07-05 2000-08-23 Astrazeneca Ab Pharmaceutical combination
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
EP1854798A3 (de) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Kondensierte heterozyklische Succinimid-Verbindungen und Analoga daraus, Modulatoren der nuklearen Hormonrezeptorfunktion
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6607755B2 (en) * 2001-06-21 2003-08-19 Michael Donald Farley Anti-aromatase pharmaceutical composition for controlling testosterone/estrone ratios
SE0103839D0 (sv) * 2001-11-16 2001-11-16 Astrazeneca Ab Pharmaceutical formulation & product
WO2003053358A2 (en) * 2001-12-19 2003-07-03 Bristol-Myers Squibb Company Fused heterocyclic compounds and analogs thereof: modulators of nuclear hormone receptor function
WO2004058234A2 (en) 2002-12-27 2004-07-15 Schering Aktiengesellschaft Pharmaceutical combinations of phthalazine vegf inhibitors and benzamide hdac inhibitors
DK2500062T3 (en) * 2007-11-13 2015-09-21 Curadis Gmbh C-19 steroids to specific therapeutic applications,
EP2387401A1 (de) * 2009-01-14 2011-11-23 Boehringer Ingelheim International GmbH Verfahren zur behandlung von kolorektalkarzinom
PT2965759T (pt) 2012-02-06 2020-02-07 Innovative Med Concepts Llc Composto antiviral e inibidor e terapia de combinação do inibidor de cox-2 para fibromialgia
EP2762135A1 (de) * 2013-02-04 2014-08-06 Sanofi Verfahren zur Verringerung des Risikos auf einer schädlichen Teriflunomid- und Rosuvastatininteraktion bei Patienten mit Multipler Sklerose
EP3129015B1 (de) * 2014-04-08 2021-07-14 The Methodist Hospital Inos-hemmende zusammensetzungen und deren verwendung als brustkrebs-therapeutika

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3423507A (en) * 1966-02-25 1969-01-21 Schering Corp Method of treating benign prostratic hypertrophy
US3449494A (en) * 1966-09-29 1969-06-10 Squibb & Sons Inc Anti-inflammatory compositions containing a corticoidal steroid and a testololactone
US4055641A (en) * 1976-05-10 1977-10-25 Richardson-Merrell Inc. Method of treating benign prostatic hypertrophy
DE2817157A1 (de) * 1978-04-17 1979-10-25 Schering Ag Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie
US4235893A (en) * 1978-05-08 1980-11-25 Brodie Angela M Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
EP0100566B1 (de) * 1982-07-14 1986-02-19 Akzo N.V. 19-Thioandrostan-Derivate

Also Published As

Publication number Publication date
DK354881A (da) 1982-11-23
IT8123988A0 (it) 1981-09-16
AU8407582A (en) 1982-11-25
US4598072A (en) 1986-07-01
IT1139175B (it) 1986-09-24
GB2102287A (en) 1983-02-02
BE890522A (fr) 1982-03-29
FR2506158A1 (fr) 1982-11-26
JPS57193412A (en) 1982-11-27
DE3121152C2 (de) 1991-02-07
CA1186998A (en) 1985-05-14
JPH0150207B2 (de) 1989-10-27
CH648211A5 (de) 1985-03-15
LU83545A1 (de) 1981-12-01
NL8103875A (nl) 1982-12-16
DE3121152A1 (de) 1982-12-09
AU563785B2 (en) 1987-07-23
FR2506158B1 (fr) 1986-05-09
ZA823501B (en) 1983-03-30
GB2102287B (en) 1985-02-27
SE8104624L (sv) 1982-11-23

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