IT8123988A0 - Impiego della combinazione di un inibitore della aromatasi con un antiandrogeno per la profilassi ela terapia dell'iperplasia della prostata. - Google Patents

Impiego della combinazione di un inibitore della aromatasi con un antiandrogeno per la profilassi ela terapia dell'iperplasia della prostata.

Info

Publication number
IT8123988A0
IT8123988A0 IT8123988A IT2398881A IT8123988A0 IT 8123988 A0 IT8123988 A0 IT 8123988A0 IT 8123988 A IT8123988 A IT 8123988A IT 2398881 A IT2398881 A IT 2398881A IT 8123988 A0 IT8123988 A0 IT 8123988A0
Authority
IT
Italy
Prior art keywords
antiandrogen
prophylaxis
therapy
combination
aromatase inhibitor
Prior art date
Application number
IT8123988A
Other languages
English (en)
Other versions
IT1139175B (it
Inventor
Hans Udo Schweikert
Ulf Tunn
Theodor Senge
Friedmund Neumann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IT8123988A0 publication Critical patent/IT8123988A0/it
Application granted granted Critical
Publication of IT1139175B publication Critical patent/IT1139175B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT23988/81A 1981-05-22 1981-09-16 Impiego della combinazione di un inibitore della aromatasi con un antiandrogeno per la profilassi e la terapia dell iperplasia della prostata IT1139175B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813121152 DE3121152A1 (de) 1981-05-22 1981-05-22 "verwendung der kombination eines aromatase-hemmers mit einem antiandrogen zur prophylaxe und therapie der prostatahyperplasie"

Publications (2)

Publication Number Publication Date
IT8123988A0 true IT8123988A0 (it) 1981-09-16
IT1139175B IT1139175B (it) 1986-09-24

Family

ID=6133382

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23988/81A IT1139175B (it) 1981-05-22 1981-09-16 Impiego della combinazione di un inibitore della aromatasi con un antiandrogeno per la profilassi e la terapia dell iperplasia della prostata

Country Status (15)

Country Link
US (1) US4598072A (it)
JP (1) JPS57193412A (it)
AU (1) AU563785B2 (it)
BE (1) BE890522A (it)
CA (1) CA1186998A (it)
CH (1) CH648211A5 (it)
DE (1) DE3121152A1 (it)
DK (1) DK354881A (it)
FR (1) FR2506158B1 (it)
GB (1) GB2102287B (it)
IT (1) IT1139175B (it)
LU (1) LU83545A1 (it)
NL (1) NL8103875A (it)
SE (1) SE463074B (it)
ZA (1) ZA823501B (it)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3607651A1 (de) * 1986-03-06 1987-09-10 Schering Ag Kombination von aromatasehemmer und testosteron-5(alpha)-reduktase-hemmer
US4895715A (en) * 1988-04-14 1990-01-23 Schering Corporation Method of treating gynecomastia
US5364847A (en) * 1989-03-10 1994-11-15 Endorecherche Inhibitors of sex steroid biosynthesis and methods for their production and use
US5595985A (en) * 1989-03-10 1997-01-21 Endorecherche Inc. Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia
US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
ATE230994T1 (de) * 1989-07-07 2003-02-15 Endorech Inc Methode zur behandlung androgenbedingter krankheiten
DK0480950T3 (da) * 1989-07-07 1999-10-11 Endorecherche Inc Kombinationsterapi til profylakse for og/eller behandling af godartet prostatahypertrofi
DE4001060A1 (de) * 1990-01-16 1991-07-18 Kanoldt Arzneimittel Gmbh Verwendung einer ungesaettigten fettsaeure oder ihrer derivate in der human- und veterinaermedizin und zur herstellung einer arzneimittelzubereitung
CZ286894A3 (en) * 1992-05-21 1995-09-13 Endorecherche Inc Pharmaceutical preparation
GB2278054A (en) * 1993-05-18 1994-11-23 Zeneca Ltd Compounds for the treatment of urinary incontinence
CN1429104A (zh) 1998-03-11 2003-07-09 内部研究股份有限公司 5型和3型17β－羟基类固醇脱氢酶的抑制剂及其用法
DE19825591A1 (de) * 1998-06-09 1999-12-23 Jenapharm Gmbh Pharmazeutische Kombinationen zum Ausgleich eines Testosteron-Defizits beim Mann mit gleichzeitigem Schutz der Prostata
GB9930839D0 (en) * 1999-12-30 2000-02-16 Pharmacia & Upjohn Spa Process for treating gynecomastia
GB0012293D0 (en) * 2000-05-23 2000-07-12 Astrazeneca Ab Pharmaceutical combination
US7001911B2 (en) * 2000-06-28 2006-02-21 Bristol-Myers Squibb Company Fused cyclic modulators of nuclear hormone receptor function
KR20030016310A (ko) * 2000-06-28 2003-02-26 브리스톨-마이어스스퀴브컴파니 선택적 안드로겐 수용체 조절제, 및 그의 확인, 고안 및사용 방법
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
WO2002002113A1 (en) * 2000-07-05 2002-01-10 Astrazeneca Ab Pharmaceutical combination of an anti-androgen and letrozole for providing an anit-androgenic effect and aromatase inhibition
GB0016426D0 (en) * 2000-07-05 2000-08-23 Astrazeneca Ab Pharmaceutical combination
WO2002002112A1 (en) * 2000-07-05 2002-01-10 Astrazeneca Ab Pharmaceutical combination of an anti-androgen and anastrozole for providing an antiandrogenic effect and aromatase inhibition
EP1854798A3 (en) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6607755B2 (en) * 2001-06-21 2003-08-19 Michael Donald Farley Anti-aromatase pharmaceutical composition for controlling testosterone/estrone ratios
SE0103839D0 (sv) * 2001-11-16 2001-11-16 Astrazeneca Ab Pharmaceutical formulation & product
JP4434740B2 (ja) * 2001-12-19 2010-03-17 ブリストル−マイヤーズ スクイブ カンパニー 核ホルモン受容体機能の調節剤である、縮合ヘテロ環化合物およびその類似体
JP2006514991A (ja) 2002-12-27 2006-05-18 シエーリング アクチエンゲゼルシャフト 新規医薬組合せ
ES2539800T3 (es) * 2007-11-13 2015-07-06 Curadis Gmbh Esteroides C-19 para usos terapéuticos
US20120157472A1 (en) * 2009-01-14 2012-06-21 Boehringer Ingelheim International Gmbh Method for treating colorectal cancer
KR101485748B1 (ko) 2012-02-06 2015-01-22 윌리엄 엘. 프리드젠 팜시클로비어 및 셀레콕시브를 포함한, 기능성 신체 증후군에 대한 항바이러스 화합물 및 cox-2 억제제 조합 치료법
EP2762135A1 (en) * 2013-02-04 2014-08-06 Sanofi Methods for reducing the risk of an adverse teriflunomide and rosuvastatin interaction in multiple sclerosis patients
SG11201607795UA (en) * 2014-04-08 2016-10-28 Methodist Hospital Inos-inhibitory compositions and their use as breast cancer therapeutics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3423507A (en) * 1966-02-25 1969-01-21 Schering Corp Method of treating benign prostratic hypertrophy
US3449494A (en) * 1966-09-29 1969-06-10 Squibb & Sons Inc Anti-inflammatory compositions containing a corticoidal steroid and a testololactone
US4055641A (en) * 1976-05-10 1977-10-25 Richardson-Merrell Inc. Method of treating benign prostatic hypertrophy
DE2817157A1 (de) * 1978-04-17 1979-10-25 Schering Ag Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie
US4235893A (en) * 1978-05-08 1980-11-25 Brodie Angela M Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
DE3362176D1 (en) * 1982-07-14 1986-03-27 Akzo Nv Novel 19-thio-androstane derivatives

Also Published As

Publication number Publication date
GB2102287A (en) 1983-02-02
AU8407582A (en) 1982-11-25
AU563785B2 (en) 1987-07-23
US4598072A (en) 1986-07-01
FR2506158A1 (fr) 1982-11-26
CH648211A5 (de) 1985-03-15
IT1139175B (it) 1986-09-24
BE890522A (fr) 1982-03-29
SE8104624L (sv) 1982-11-23
JPS57193412A (en) 1982-11-27
CA1186998A (en) 1985-05-14
GB2102287B (en) 1985-02-27
FR2506158B1 (fr) 1986-05-09
NL8103875A (nl) 1982-12-16
SE463074B (sv) 1990-10-08
DE3121152A1 (de) 1982-12-09
LU83545A1 (de) 1981-12-01
DK354881A (da) 1982-11-23
ZA823501B (en) 1983-03-30
DE3121152C2 (it) 1991-02-07
JPH0150207B2 (it) 1989-10-27

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