SE455162B - Antitumorkomposition i form av ett oralt farmaceutiskt preparat eller ett suppositorium, innehallande en ester av 1-beta-d-arabinofuranosylcytosin-5'-fosfat - Google Patents
Antitumorkomposition i form av ett oralt farmaceutiskt preparat eller ett suppositorium, innehallande en ester av 1-beta-d-arabinofuranosylcytosin-5'-fosfatInfo
- Publication number
- SE455162B SE455162B SE7905375A SE7905375A SE455162B SE 455162 B SE455162 B SE 455162B SE 7905375 A SE7905375 A SE 7905375A SE 7905375 A SE7905375 A SE 7905375A SE 455162 B SE455162 B SE 455162B
- Authority
- SE
- Sweden
- Prior art keywords
- ester
- ara
- cmp
- arabinofuranosylcytosine
- phosphate
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7369878A JPS552601A (en) | 1978-06-20 | 1978-06-20 | Anti-tumor agent for non-injection use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7905375L SE7905375L (sv) | 1979-12-21 |
| SE455162B true SE455162B (sv) | 1988-06-27 |
Family
ID=13525685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7905375A SE455162B (sv) | 1978-06-20 | 1979-06-19 | Antitumorkomposition i form av ett oralt farmaceutiskt preparat eller ett suppositorium, innehallande en ester av 1-beta-d-arabinofuranosylcytosin-5'-fosfat |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4542021A (cs) |
| JP (1) | JPS552601A (cs) |
| CH (1) | CH638982A5 (cs) |
| DE (1) | DE2924691A1 (cs) |
| FR (1) | FR2429019A1 (cs) |
| GB (1) | GB2023422B (cs) |
| IT (1) | IT1206968B (cs) |
| NL (1) | NL190955C (cs) |
| SE (1) | SE455162B (cs) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS552602A (en) * | 1978-06-20 | 1980-01-10 | Yamasa Shoyu Co Ltd | 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester |
| DE3263939D1 (en) * | 1981-12-09 | 1985-07-04 | Teijin Ltd | 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof |
| JPS58225097A (ja) * | 1982-06-23 | 1983-12-27 | Yamasa Shoyu Co Ltd | ヌクレオシド５′−アルキルもしくはアルケニルりん酸 |
| JPS5925327A (ja) * | 1982-07-31 | 1984-02-09 | Hidematsu Hirai | 抗腫瘍性複合体の製造方法 |
| ES2031462T3 (es) * | 1986-03-24 | 1992-12-16 | Nippon Kayaku Kabushiki Kaisha | Procedimiento para producir 1-b-d-arabinofuranosilcitosina-5'-estearilfosfato monosodico y monohidrato de la misma, y compuesto farmaceutico que contiene esta ultima. |
| EP0563697B1 (en) * | 1992-04-03 | 2001-07-04 | Nippon Kayaku Kabushiki Kaisha | Cytarabine ocfosfate hard capsule |
| DE4402492A1 (de) * | 1994-01-28 | 1995-08-03 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern |
| GB2389788B (en) * | 2000-12-23 | 2005-07-20 | Univ Creighton | Methods for inducing apoptosis and inhibiting proliferation in cancer cells |
| US20040072902A1 (en) * | 2001-12-24 | 2004-04-15 | Adrian Thomas E. | Methods for inducing apoptosis and inhibiting proliferation in cancer cells |
| US7524831B2 (en) * | 2005-03-02 | 2009-04-28 | Schering Corporation | Treatments for Flaviviridae virus infection |
| CN102115485A (zh) * | 2009-12-30 | 2011-07-06 | 济南圣鲁金药物技术开发有限公司 | 基于阿糖胞苷结构的前药及其合成方法及应用 |
| TW201524990A (zh) | 2013-10-11 | 2015-07-01 | Alios Biopharma Inc | 經取代之核苷、核苷酸及其類似物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1792447C3 (de) * | 1968-09-04 | 1978-05-11 | Fa. Heinrich Mack Nachf., 7919 Au | Oral anwendbares, cytostatisches Mittel |
| DE2438322C3 (de) * | 1974-08-09 | 1979-02-08 | Chemische Werke Huels Ag, 4370 Marl | Verfahren zur Herstellung von Polymerisaten mit breiter Molekulargewichtsverteilung |
| US4086417A (en) * | 1974-10-15 | 1978-04-25 | Asahi Kasei Kogyo Kabushiki Kaisha | Cytidine nucleotide derivatives |
| JPS5289681A (en) * | 1976-01-22 | 1977-07-27 | Yamasa Shoyu Co Ltd | Preparation of aracytidine -5# phosphoric acid ester derivatives |
| JPS552602A (en) * | 1978-06-20 | 1980-01-10 | Yamasa Shoyu Co Ltd | 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester |
-
1978
- 1978-06-20 JP JP7369878A patent/JPS552601A/ja active Granted
-
1979
- 1979-06-15 CH CH561979A patent/CH638982A5/fr not_active IP Right Cessation
- 1979-06-18 IT IT7949442A patent/IT1206968B/it active
- 1979-06-18 GB GB7921147A patent/GB2023422B/en not_active Expired
- 1979-06-18 FR FR7915500A patent/FR2429019A1/fr active Granted
- 1979-06-19 DE DE19792924691 patent/DE2924691A1/de active Granted
- 1979-06-19 SE SE7905375A patent/SE455162B/sv unknown
- 1979-06-19 NL NL7904771A patent/NL190955C/xx not_active IP Right Cessation
-
1980
- 1980-11-10 US US06/205,592 patent/US4542021A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IT7949442A0 (it) | 1979-06-18 |
| GB2023422B (en) | 1983-01-06 |
| DE2924691A1 (de) | 1980-01-17 |
| GB2023422A (en) | 1980-01-03 |
| JPS5748091B2 (cs) | 1982-10-14 |
| FR2429019B1 (cs) | 1982-11-05 |
| US4542021A (en) | 1985-09-17 |
| NL7904771A (nl) | 1979-12-27 |
| IT1206968B (it) | 1989-05-17 |
| CH638982A5 (fr) | 1983-10-31 |
| NL190955B (nl) | 1994-06-16 |
| JPS552601A (en) | 1980-01-10 |
| FR2429019A1 (fr) | 1980-01-18 |
| SE7905375L (sv) | 1979-12-21 |
| DE2924691C2 (cs) | 1991-10-10 |
| NL190955C (nl) | 1994-11-16 |
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| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
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