SE453916B - Nya aromatiska aminoalkoxiderivat, deras framstellningssett och lekemedel anvendbart som kalciumantagonist - Google Patents
Nya aromatiska aminoalkoxiderivat, deras framstellningssett och lekemedel anvendbart som kalciumantagonistInfo
- Publication number
- SE453916B SE453916B SE8207224A SE8207224A SE453916B SE 453916 B SE453916 B SE 453916B SE 8207224 A SE8207224 A SE 8207224A SE 8207224 A SE8207224 A SE 8207224A SE 453916 B SE453916 B SE 453916B
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- derivatives
- compounds
- radical
- carbon atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8124244A FR2518992A1 (fr) | 1981-12-24 | 1981-12-24 | Nouveaux derives aminoalcoxy aromatiques, leur procede de preparation et leur application en therapeutique |
FR8221053A FR2537970B1 (fr) | 1982-12-15 | 1982-12-15 | Nouveaux derives aminoalkoxy aromatiques, leur procede de preparation et leur application en therapeutique |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8207224D0 SE8207224D0 (sv) | 1982-12-17 |
SE8207224L SE8207224L (sv) | 1983-06-25 |
SE453916B true SE453916B (sv) | 1988-03-14 |
Family
ID=26222677
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8207224A SE453916B (sv) | 1981-12-24 | 1982-12-17 | Nya aromatiska aminoalkoxiderivat, deras framstellningssett och lekemedel anvendbart som kalciumantagonist |
SE8505219A SE8505219L (sv) | 1981-12-24 | 1985-11-06 | Aromatiska aminoalkoxiderivat och deras framstellningssett |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8505219A SE8505219L (sv) | 1981-12-24 | 1985-11-06 | Aromatiska aminoalkoxiderivat och deras framstellningssett |
Country Status (13)
Country | Link |
---|---|
US (3) | US4536500A (es) |
JP (1) | JPH04210944A (es) |
AU (1) | AU9193482A (es) |
CA (1) | CA1197243A (es) |
CH (2) | CH661509A5 (es) |
DE (1) | DE3247860A1 (es) |
ES (1) | ES8308864A1 (es) |
GB (2) | GB2113680B (es) |
GR (1) | GR78370B (es) |
IT (1) | IT1191152B (es) |
LU (1) | LU84548A1 (es) |
NL (1) | NL8204978A (es) |
SE (2) | SE453916B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5017572A (en) * | 1988-04-22 | 1991-05-21 | Delalande S.A. | Derivatives of 1-[3-(4-hydroxyphenyl) 1-hydroxy 1-propyl] benzene substituted in position 2 by an aminoalkyleneoxy chain, the method of preparing same and the application thereof to therapeutics |
US5270325A (en) * | 1988-07-28 | 1993-12-14 | Basf Aktiengesellschaft | P-hydroxy phenone derivatives used in the treatment of cardiac arrhythmia |
KR0139296B1 (ko) * | 1988-11-21 | 1998-05-15 | 가와무라 시게꾸니 | 칼콘 유도체 및 그 제조 방법 |
US4937235A (en) * | 1989-01-23 | 1990-06-26 | American Cyanamid Company | 3- or 4-substituted oxotremorine derivatives |
FR2646670A1 (fr) * | 1989-05-05 | 1990-11-09 | Delalande Sa | Utilisation de derives aminoalkoxy aromatiques pour le traitement des troubles du systeme cerebrovasculaire |
CA2020888A1 (en) * | 1989-07-27 | 1991-01-28 | Philippe Guerry | Substituted aminoalkoxybenzene derivatives |
US5214046A (en) * | 1989-07-27 | 1993-05-25 | Hoffmann-La Roche Inc. | Substituted aminoalkoxybenzene anti-fungicidal compositions and use |
US5356891A (en) * | 1989-09-22 | 1994-10-18 | Witiak Donald T | Phenylalkyl amine derivatives having anti-ischaemic activity |
WO1991007958A1 (en) * | 1989-12-06 | 1991-06-13 | Vsesojuzny Kardiologichesky Nauchny Tsentr | Pharmaceutical preparation-protector of myocardium under ischemia and reperfusion |
GB9321811D0 (en) * | 1993-10-22 | 1993-12-15 | Smithkline Beecham Plc | Pharmaceuticals |
FR2734831B1 (fr) * | 1995-05-29 | 1997-07-11 | Oreal | Composition solide expansee dont la matrice est constituee d'un reseau alveolaire amidonne et contenant des particules de polyamide spheroidales calibrees et utilisations en application topique |
US6509356B1 (en) | 1997-08-07 | 2003-01-21 | Eli Lilly And Company | 1-(4-(Substituted alkoxy)benzyl)naphthalene compounds having estrogen inhibitory activity |
US6054246A (en) * | 1998-07-01 | 2000-04-25 | Polaroid Corporation | Heat and radiation-sensitive imaging medium, and processes for use thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB377464A (en) * | 1930-08-28 | 1932-07-28 | Chem Ind Basel | Manufacture of substituted aromatic ketones |
GB730922A (en) * | 1952-04-24 | 1955-06-01 | Roche Products Ltd | Aromatic amino-ketones and acid addition salts thereof and a process for the manufacture of same |
US2668850A (en) * | 1952-04-24 | 1954-02-09 | Hoffmann La Roche | Phenyl-phenethyl ketones |
GB872997A (en) * | 1957-01-26 | 1961-07-19 | Pharmacia Ab | Substituted ún-aminoalkoxy-acyl benzenes and processes for their manufacture |
GB905903A (en) * | 1960-05-25 | 1962-09-12 | Guidotti & C Spa Labor | Dialkylaminoethoxyketones having a coronary-dilating action and methods of preparingthem |
US3077472A (en) * | 1961-03-21 | 1963-02-12 | Univ Kansas Res Foundation | 3-[4-(aminoalkoxy)-phenyl]-4-(4-oxyphenyl)-alkanes and alkenes |
GB1063744A (en) * | 1964-05-25 | 1967-03-30 | American Cyanamid Co | 4-substituted-4'-tertiary aminoalkoxy biphenyls |
GB1111338A (en) * | 1964-07-24 | 1968-04-24 | Fisons Pharmaceuticals Ltd | Aralkyl substituted resorcinols |
FR5733M (es) * | 1966-09-27 | 1968-01-22 | ||
GB1388088A (en) * | 1973-05-16 | 1975-03-19 | Inst Med Parazitologii I Tropi | N-b-2-acetyl-4-chloro-phenoxy-ethyl-n,n-dimethyl-n-benzyl- ammonium-p-chlorobenzene sulphonate method for preparing same and medicinal preparation based thereon |
-
1982
- 1982-04-13 GR GR70145A patent/GR78370B/el unknown
- 1982-12-17 SE SE8207224A patent/SE453916B/sv not_active IP Right Cessation
- 1982-12-20 CA CA000418154A patent/CA1197243A/en not_active Expired
- 1982-12-21 CH CH3696/85A patent/CH661509A5/fr not_active IP Right Cessation
- 1982-12-21 US US06/451,537 patent/US4536500A/en not_active Expired - Fee Related
- 1982-12-21 CH CH7473/82A patent/CH655313A5/fr not_active IP Right Cessation
- 1982-12-22 LU LU84548A patent/LU84548A1/fr unknown
- 1982-12-22 GB GB08236432A patent/GB2113680B/en not_active Expired
- 1982-12-23 NL NL8204978A patent/NL8204978A/nl not_active Application Discontinuation
- 1982-12-23 IT IT24964/82A patent/IT1191152B/it active
- 1982-12-23 DE DE19823247860 patent/DE3247860A1/de active Granted
- 1982-12-23 ES ES518518A patent/ES8308864A1/es not_active Expired
- 1982-12-24 AU AU91934/82A patent/AU9193482A/en not_active Abandoned
-
1985
- 1985-03-15 GB GB08506732A patent/GB2154587B/en not_active Expired
- 1985-06-26 US US06/748,862 patent/US4732896A/en not_active Expired - Fee Related
- 1985-11-06 SE SE8505219A patent/SE8505219L/xx not_active Application Discontinuation
-
1988
- 1988-01-22 US US07/147,268 patent/US4831051A/en not_active Expired - Fee Related
-
1991
- 1991-02-27 JP JP3033043A patent/JPH04210944A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU9193482A (en) | 1983-09-01 |
ES518518A0 (es) | 1983-10-01 |
DE3247860A1 (de) | 1983-07-28 |
GB2113680A (en) | 1983-08-10 |
CA1197243A (en) | 1985-11-26 |
SE8505219D0 (sv) | 1985-11-06 |
US4536500A (en) | 1985-08-20 |
GB2154587B (en) | 1986-08-20 |
CH661509A5 (fr) | 1987-07-31 |
JPH04210944A (ja) | 1992-08-03 |
IT8224964A0 (it) | 1982-12-23 |
LU84548A1 (fr) | 1984-10-22 |
GB2154587A (en) | 1985-09-11 |
DE3247860C2 (es) | 1993-08-05 |
GR78370B (es) | 1984-09-26 |
SE8207224L (sv) | 1983-06-25 |
GB2113680B (en) | 1986-08-13 |
IT1191152B (it) | 1988-02-24 |
US4732896A (en) | 1988-03-22 |
GB8506732D0 (en) | 1985-04-17 |
ES8308864A1 (es) | 1983-10-01 |
SE8207224D0 (sv) | 1982-12-17 |
NL8204978A (nl) | 1983-07-18 |
CH655313A5 (fr) | 1986-04-15 |
SE8505219L (sv) | 1985-11-06 |
US4831051A (en) | 1989-05-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE453916B (sv) | Nya aromatiska aminoalkoxiderivat, deras framstellningssett och lekemedel anvendbart som kalciumantagonist | |
Thomas et al. | Repetitive Diels-Alder reactions for the growth of linear polyacenequinoid derivatives | |
US4719055A (en) | Phenanthrene derivatives | |
JPH03178977A (ja) | ジテルペンラクトン化合物及びその製造方法 | |
JPH0217179A (ja) | 環置換2―アミノ―1,2,3,4―テトラヒドロナフタレン類 | |
Garratt et al. | Diastereomeric monocyclic diallenes. Synthesis and properties of the diastereomeric 3, 4, 9, 10-cyclododecatetraene-1, 7-diones and 3, 4, 10, 11-cyclotetradecatetraene-1, 8-diones | |
Piers et al. | Total synthesis, stereochemistry, and lithium–ammonia reduction of (±)-4-demethylaristolone and (±)-5-epi-4-demethylaristolone | |
Green et al. | Synthesis and pharmacological properties of a series of 2-substituted aminomethyl-1, 4-benzodioxanes | |
Jones et al. | Theoretical interpretations of some experimental observations in reactions of triazolopyridines and their quaternary salts | |
KOIKE et al. | Studies on the Alkaloids of Picrasma quassioides BENNET. VIII.: X-Ray Crystal Structure Analysis of Picrasidine-F | |
US4474967A (en) | 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione | |
Mitchell et al. | The synthesis of a cyclophane containing two bridged annulene units | |
US4716172A (en) | 4-substituted octahydroquinolizine analgesic compounds and octahydroquinolizinium intermediates | |
Matsumoto et al. | The total synthesis of (+)-totarol and (+)-podototarin. | |
Ando et al. | The total syntheses of chamaecynone, isochamaecynone, and dihydroisochamaecynone. | |
Turner et al. | Synthetic Intermediates Related to the Diterpene Alkaloids1, 2 | |
Stephanidou‐Stephanatou et al. | Oxidation of arylacetylhydrazones of carbonyl compounds with lead tetraacetate | |
US3041355A (en) | Products related to muscarine and the preparation of such products | |
Halton et al. | Studies in the cycloproparene series: Approaches to octahydrocyclopropa-[l] phenanthrenes | |
JPH09202781A (ja) | ラディシコール誘導体 | |
Jain et al. | Synthesis of isopentenylated chrystins | |
Sakakibara et al. | Photoreaction of methyl 4, 6-O-benzylidene-2, 3-dideoxy-3-nitro-β-d-erythro-hex-2-enopyranoside with 1, 3-dioxolane and tetrahydrofuran | |
US4642384A (en) | Process for the preparation of derivatives of pyrrolidine and piperidine | |
US4579950A (en) | Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine] compounds | |
US4808625A (en) | Phenanthrene derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
Ref document number: 8207224-0 Effective date: 19940710 Format of ref document f/p: F |