GB872997A - Substituted ún-aminoalkoxy-acyl benzenes and processes for their manufacture - Google Patents
Substituted ún-aminoalkoxy-acyl benzenes and processes for their manufactureInfo
- Publication number
- GB872997A GB872997A GB2265/58A GB226558A GB872997A GB 872997 A GB872997 A GB 872997A GB 2265/58 A GB2265/58 A GB 2265/58A GB 226558 A GB226558 A GB 226558A GB 872997 A GB872997 A GB 872997A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- substituted
- halogen
- aminoalkoxy
- benzenes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises compounds of the general formula <FORM:0872997/IV (b)/1> (wherein R represents a hydrocarbon radical which may be substituted, R1 a C1-C5 alkyl group or a halogen atom (preferably in position 4 or 5), B a C1-C6 alkylene group, and R2 a dialkylamino group in which each alkyl group contains up to 4 carbon atoms, or a morpholino, piperidino or pyrrolidino group) and their acid addition salts, and the preparation thereof by interaction of compounds of the general formulae <FORM:0872997/IV (b)/2> and YR2 (wherein either X represents a -B-halogen group and Y a hydrogen atom, or X represents a hydrogen or sodium atom and Y a halogen -B- group), followed, if desired, by reaction of the resulting amine with an acid. The products possess psychopharmacological activity and are also useful as local anaesthetitcs, analgesics and antihistamins.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE872997X | 1957-01-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB872997A true GB872997A (en) | 1961-07-19 |
Family
ID=20370825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2265/58A Expired GB872997A (en) | 1957-01-26 | 1958-01-23 | Substituted ún-aminoalkoxy-acyl benzenes and processes for their manufacture |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR1248417A (en) |
GB (1) | GB872997A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3261868A (en) * | 1963-03-14 | 1966-07-19 | Upjohn Co | Aminoalkoxy-hydroxyacetophenones |
US3335184A (en) * | 1963-07-26 | 1967-08-08 | Exploitations Chimi & Pharm | Ortho-diisopropylaminoethoxybutyrophenone and hydrochloride thereof |
GB2154587A (en) * | 1981-12-24 | 1985-09-11 | Delalande Sa | Aminoalkoxy-substituted aromatic ketones |
WO2021175971A1 (en) * | 2020-03-05 | 2021-09-10 | Givaudan Sa | Heterocyclic derivatives as trmp8 antagonists |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2537970B1 (en) * | 1982-12-15 | 1986-08-14 | Delalande Sa | NOVEL AMINOALKOXY AROMATIC DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS |
US4795758A (en) * | 1986-02-10 | 1989-01-03 | Societe A Responsabilite Limitee: Institut De Recherches Chimiques Et Biologiques Appliquees (I.R.C.E.B.A.) | 5-[2-(pyrrolidin-1-yl)ethoxy]-p-cymene derivatives, the process for the preparation of the said derivatives and drugs in which the said derivatives are present |
-
1958
- 1958-01-23 GB GB2265/58A patent/GB872997A/en not_active Expired
- 1958-01-24 FR FR756646A patent/FR1248417A/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3261868A (en) * | 1963-03-14 | 1966-07-19 | Upjohn Co | Aminoalkoxy-hydroxyacetophenones |
US3335184A (en) * | 1963-07-26 | 1967-08-08 | Exploitations Chimi & Pharm | Ortho-diisopropylaminoethoxybutyrophenone and hydrochloride thereof |
GB2154587A (en) * | 1981-12-24 | 1985-09-11 | Delalande Sa | Aminoalkoxy-substituted aromatic ketones |
WO2021175971A1 (en) * | 2020-03-05 | 2021-09-10 | Givaudan Sa | Heterocyclic derivatives as trmp8 antagonists |
CN115243764A (en) * | 2020-03-05 | 2022-10-25 | 奇华顿股份有限公司 | Heterocyclic derivatives as TRMP8 antagonists |
Also Published As
Publication number | Publication date |
---|---|
FR1248417A (en) | 1960-11-07 |
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