GB905903A - Dialkylaminoethoxyketones having a coronary-dilating action and methods of preparingthem - Google Patents

Dialkylaminoethoxyketones having a coronary-dilating action and methods of preparingthem

Info

Publication number
GB905903A
GB905903A GB18575/60A GB1857560A GB905903A GB 905903 A GB905903 A GB 905903A GB 18575/60 A GB18575/60 A GB 18575/60A GB 1857560 A GB1857560 A GB 1857560A GB 905903 A GB905903 A GB 905903A
Authority
GB
United Kingdom
Prior art keywords
halide
methyl
hydrogen
coronary
stands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB18575/60A
Inventor
Gianfranco Di Paco
Celesio Sonnino Tauro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio Guidotti SpA
Original Assignee
Laboratorio Guidotti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Guidotti SpA filed Critical Laboratorio Guidotti SpA
Priority to GB18575/60A priority Critical patent/GB905903A/en
Publication of GB905903A publication Critical patent/GB905903A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

The invention comprises coronary-dilating compounds of the general formula:- <FORM:0905903/IV (b)/1> in which R represents methyl, b -phenylethyl or a -phenylpropyl, one of the letters a or c stands for the group -OCH2CH2X and the remaining letters stand for hydrogen, and X represents a dimethylamino or diethylamino group or a hydrogen halide of the same, or stands for a quaternary nitrogen atom so associated with methyl or ethyl groups that the derivative associated with a halogen is a tri-methyl or triethyl quaternary amine, together with processes for their preparation by reacting the appropriate o- or p-hydroxy substituted ketone or an alkali metal derivative thereof with the appropriate b -dialkylaminoethyl halide or its hydrochloride in the presence of a condensation agent which causes the condensation of the two reactants with the removal of hydrogen halide or an alkali metal halide. Detailed examples illustrate the invention.
GB18575/60A 1960-05-25 1960-05-25 Dialkylaminoethoxyketones having a coronary-dilating action and methods of preparingthem Expired GB905903A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB18575/60A GB905903A (en) 1960-05-25 1960-05-25 Dialkylaminoethoxyketones having a coronary-dilating action and methods of preparingthem

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB18575/60A GB905903A (en) 1960-05-25 1960-05-25 Dialkylaminoethoxyketones having a coronary-dilating action and methods of preparingthem

Publications (1)

Publication Number Publication Date
GB905903A true GB905903A (en) 1962-09-12

Family

ID=10114803

Family Applications (1)

Application Number Title Priority Date Filing Date
GB18575/60A Expired GB905903A (en) 1960-05-25 1960-05-25 Dialkylaminoethoxyketones having a coronary-dilating action and methods of preparingthem

Country Status (1)

Country Link
GB (1) GB905903A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2154587A (en) * 1981-12-24 1985-09-11 Delalande Sa Aminoalkoxy-substituted aromatic ketones
US20200392073A1 (en) * 2016-05-24 2020-12-17 Temple University-Of The Commonwealth System Of Higher Education Novel functionalized n,n-dialkylamino phenyl ethers and their method of use

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2154587A (en) * 1981-12-24 1985-09-11 Delalande Sa Aminoalkoxy-substituted aromatic ketones
US20200392073A1 (en) * 2016-05-24 2020-12-17 Temple University-Of The Commonwealth System Of Higher Education Novel functionalized n,n-dialkylamino phenyl ethers and their method of use
US11873267B2 (en) * 2016-05-24 2024-01-16 Temple University-Of The Commonwealth System Of Higher Education Functionalized N,N-dialkylamino phenyl ethers and their method of use

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