SE449101B - 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar - Google Patents
1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingarInfo
- Publication number
- SE449101B SE449101B SE8200679A SE8200679A SE449101B SE 449101 B SE449101 B SE 449101B SE 8200679 A SE8200679 A SE 8200679A SE 8200679 A SE8200679 A SE 8200679A SE 449101 B SE449101 B SE 449101B
- Authority
- SE
- Sweden
- Prior art keywords
- benzyl
- group
- formula
- reaction
- dioxopiperazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56015837A JPS57140783A (en) | 1981-02-06 | 1981-02-06 | 1-benzyl-4-(4-(2-pyrimidinylamino)benzyl)-2, 3-dioxopiperazine derivative and its salt, their preparation, and carcinostatic agent containing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8200679L SE8200679L (sv) | 1982-09-22 |
| SE449101B true SE449101B (sv) | 1987-04-06 |
Family
ID=11899943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8200679A SE449101B (sv) | 1981-02-06 | 1982-02-05 | 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS57140783A (ro) |
| KR (1) | KR880001105B1 (ro) |
| AU (1) | AU537512B2 (ro) |
| BE (1) | BE892032A (ro) |
| CH (1) | CH651036A5 (ro) |
| DE (1) | DE3204074A1 (ro) |
| ES (2) | ES8304970A1 (ro) |
| FR (1) | FR2499569A1 (ro) |
| GB (1) | GB2094296B (ro) |
| IT (1) | IT1154274B (ro) |
| NL (1) | NL8200451A (ro) |
| SE (1) | SE449101B (ro) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU742388B2 (en) * | 1996-12-24 | 2002-01-03 | Chugai Seiyaku Kabushiki Kaisha | Aromatic amine derivatives having nos inhibiting action |
| US11542222B2 (en) * | 2018-04-11 | 2023-01-03 | Mitsubishi Gas Chemical Company, Inc. | Method for preparing dicyanoalkane and bis(aminomethyl) alkane |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5618969A (en) * | 1979-07-24 | 1981-02-23 | Toyama Chem Co Ltd | Novel 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative, its acid addition salt, and their preparation |
-
1981
- 1981-02-06 JP JP56015837A patent/JPS57140783A/ja active Granted
-
1982
- 1982-02-04 CH CH674/82A patent/CH651036A5/de not_active IP Right Cessation
- 1982-02-05 NL NL8200451A patent/NL8200451A/nl not_active Application Discontinuation
- 1982-02-05 FR FR8201925A patent/FR2499569A1/fr active Granted
- 1982-02-05 AU AU80240/82A patent/AU537512B2/en not_active Ceased
- 1982-02-05 IT IT8247729A patent/IT1154274B/it active
- 1982-02-05 BE BE0/207239A patent/BE892032A/fr not_active IP Right Cessation
- 1982-02-05 ES ES509391A patent/ES8304970A1/es not_active Expired
- 1982-02-05 GB GB8203333A patent/GB2094296B/en not_active Expired
- 1982-02-05 SE SE8200679A patent/SE449101B/sv unknown
- 1982-02-06 KR KR8200513A patent/KR880001105B1/ko active
- 1982-02-06 DE DE19823204074 patent/DE3204074A1/de active Granted
- 1982-12-16 ES ES518304A patent/ES518304A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| CH651036A5 (de) | 1985-08-30 |
| BE892032A (fr) | 1982-08-05 |
| GB2094296A (en) | 1982-09-15 |
| FR2499569A1 (fr) | 1982-08-13 |
| IT8247729A0 (it) | 1982-02-05 |
| JPS57140783A (en) | 1982-08-31 |
| GB2094296B (en) | 1985-02-13 |
| SE8200679L (sv) | 1982-09-22 |
| FR2499569B1 (ro) | 1985-02-22 |
| AU537512B2 (en) | 1984-06-28 |
| JPS6366319B2 (ro) | 1988-12-20 |
| KR830009090A (ko) | 1983-12-17 |
| IT1154274B (it) | 1987-01-21 |
| NL8200451A (nl) | 1982-09-01 |
| ES8402285A1 (es) | 1984-01-16 |
| ES509391A0 (es) | 1983-03-16 |
| ES518304A0 (es) | 1984-01-16 |
| AU8024082A (en) | 1982-08-12 |
| ES8304970A1 (es) | 1983-03-16 |
| DE3204074C2 (ro) | 1987-12-23 |
| DE3204074A1 (de) | 1982-10-28 |
| KR880001105B1 (ko) | 1988-06-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4323570A (en) | Substituted aminopyrimidines | |
| SU1535379A3 (ru) | Способ получени 5-замещенных 2,4-диаминопиримидинов или их кислотно-аддитивных солей | |
| EP0371139B1 (en) | 6-substituted acyclicpyrimidine nucleoside derivatives and antiviral agents containing same as active ingredients | |
| DK160492B (da) | Pyrimidinderivater, fremgangsmaader til fremstilling heraf samt farmaceutiske praeparater indeholdende disse derivater | |
| NO126322B (ro) | ||
| US5461060A (en) | Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof | |
| KR100238562B1 (ko) | 피페리딘 유도체 화합물 | |
| HU205917B (en) | Process for producing 6-substituted pyrimidine derivatives and antiviral pharmaceutical compositions containing them as active components | |
| US3962443A (en) | Antibacterial pharmaceutical compositions and processes for preparation thereof | |
| US3463850A (en) | Arabinofuranosyl 2-thiopyrimidines and pharmaceutical compositions thereof | |
| US5318972A (en) | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | |
| HU187673B (en) | Process for preparing 2-piperazino-pyrimidine derivatives | |
| SE449101B (sv) | 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar | |
| HU223477B1 (hu) | Új azetidin-intermedier | |
| US3839569A (en) | Certain s-triazolo (4,3-a)quinolines as agents for control of plant pathogens | |
| JPH0417957B2 (ro) | ||
| DE69025084T2 (de) | Hexitolderivate | |
| EP0425669A1 (en) | 1-amino-5-halogenouracils, process for their preparation, and central nervous system depressants containing same as active ingredient | |
| US3729477A (en) | Certain 4-(3-amino-2-hydroxypropoxy)-1,2,5-thiadiazole-3-carboxamides | |
| JPH0696572B2 (ja) | ピリドンカルボン酸誘導体、そのエステルおよびその塩 | |
| US4738960A (en) | 1,3,4-Thiadiazole derivatives and pharmaceutical preparations useful as inhibitors for histamine-H2 receptors | |
| JPH0635458B2 (ja) | ピリドンカルボン酸誘導体、そのエステルおよびその塩 | |
| CA2040885A1 (en) | Substituted benzhydryl 2-hydroxypropyl piperazine derivatives | |
| WO1994003450A1 (en) | Furylthiazole and their use as h2-receptor antagonists and antimicrobial agents | |
| JPS6340190B2 (ro) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
Ref document number: 8200679-2 Format of ref document f/p: F |