SE449101B - 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar - Google Patents

1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar

Info

Publication number
SE449101B
SE449101B SE8200679A SE8200679A SE449101B SE 449101 B SE449101 B SE 449101B SE 8200679 A SE8200679 A SE 8200679A SE 8200679 A SE8200679 A SE 8200679A SE 449101 B SE449101 B SE 449101B
Authority
SE
Sweden
Prior art keywords
benzyl
group
formula
reaction
dioxopiperazine
Prior art date
Application number
SE8200679A
Other languages
English (en)
Swedish (sv)
Other versions
SE8200679L (sv
Inventor
T Hori
C Yoshida
Y Kiba
R Takeno
J Nakano
J Nitta
S Kishimoto
S Murakami
H Tsuda
I Saikawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of SE8200679L publication Critical patent/SE8200679L/xx
Publication of SE449101B publication Critical patent/SE449101B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE8200679A 1981-02-06 1982-02-05 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar SE449101B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56015837A JPS57140783A (en) 1981-02-06 1981-02-06 1-benzyl-4-(4-(2-pyrimidinylamino)benzyl)-2, 3-dioxopiperazine derivative and its salt, their preparation, and carcinostatic agent containing the same

Publications (2)

Publication Number Publication Date
SE8200679L SE8200679L (sv) 1982-09-22
SE449101B true SE449101B (sv) 1987-04-06

Family

ID=11899943

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8200679A SE449101B (sv) 1981-02-06 1982-02-05 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar

Country Status (12)

Country Link
JP (1) JPS57140783A (OSRAM)
KR (1) KR880001105B1 (OSRAM)
AU (1) AU537512B2 (OSRAM)
BE (1) BE892032A (OSRAM)
CH (1) CH651036A5 (OSRAM)
DE (1) DE3204074A1 (OSRAM)
ES (2) ES509391A0 (OSRAM)
FR (1) FR2499569A1 (OSRAM)
GB (1) GB2094296B (OSRAM)
IT (1) IT1154274B (OSRAM)
NL (1) NL8200451A (OSRAM)
SE (1) SE449101B (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998028257A1 (en) * 1996-12-24 1998-07-02 Chugai Seiyaku Kabushiki Kaisha Aromatic amine derivatives having nos inhibitory effect
EP3778559A4 (en) * 2018-04-11 2021-05-12 Mitsubishi Gas Chemical Company, Inc. PROCESS FOR THE PRODUCTION OF DICYANOALKANE AND UP TO (AMINOMETHYL) ALKANE
WO2020195252A1 (ja) * 2019-03-27 2020-10-01 ダイキン工業株式会社 ハロゲン化シクロアルカン化合物の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5618969A (en) * 1979-07-24 1981-02-23 Toyama Chem Co Ltd Novel 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative, its acid addition salt, and their preparation

Also Published As

Publication number Publication date
GB2094296B (en) 1985-02-13
NL8200451A (nl) 1982-09-01
JPS6366319B2 (OSRAM) 1988-12-20
FR2499569A1 (fr) 1982-08-13
IT1154274B (it) 1987-01-21
KR830009090A (ko) 1983-12-17
GB2094296A (en) 1982-09-15
AU537512B2 (en) 1984-06-28
IT8247729A0 (it) 1982-02-05
AU8024082A (en) 1982-08-12
BE892032A (fr) 1982-08-05
CH651036A5 (de) 1985-08-30
SE8200679L (sv) 1982-09-22
ES8304970A1 (es) 1983-03-16
ES509391A0 (es) 1983-03-16
FR2499569B1 (OSRAM) 1985-02-22
ES8402285A1 (es) 1984-01-16
DE3204074C2 (OSRAM) 1987-12-23
JPS57140783A (en) 1982-08-31
ES518304A0 (es) 1984-01-16
KR880001105B1 (ko) 1988-06-29
DE3204074A1 (de) 1982-10-28
IT8247729A1 (it) 1983-08-05

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