SE447700B - Stabilisering av meningokockpolysackarid, vaccin innehallande polysackariden och stabilisator(er) samt anvendningen av sackaros, raffinos eller glutaminat och eventuellt laktos som stabilisator - Google Patents

Stabilisering av meningokockpolysackarid, vaccin innehallande polysackariden och stabilisator(er) samt anvendningen av sackaros, raffinos eller glutaminat och eventuellt laktos som stabilisator

Info

Publication number
SE447700B
SE447700B SE7811083A SE7811083A SE447700B SE 447700 B SE447700 B SE 447700B SE 7811083 A SE7811083 A SE 7811083A SE 7811083 A SE7811083 A SE 7811083A SE 447700 B SE447700 B SE 447700B
Authority
SE
Sweden
Prior art keywords
stabilizer
lactose
polysaccaride
glutaminate
sucrose
Prior art date
Application number
SE7811083A
Other languages
English (en)
Swedish (sv)
Other versions
SE7811083L (sv
Inventor
G Guthohrlein
T B Helting
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of SE7811083L publication Critical patent/SE7811083L/xx
Publication of SE447700B publication Critical patent/SE447700B/sv

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
SE7811083A 1977-10-27 1978-10-25 Stabilisering av meningokockpolysackarid, vaccin innehallande polysackariden och stabilisator(er) samt anvendningen av sackaros, raffinos eller glutaminat och eventuellt laktos som stabilisator SE447700B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772748132 DE2748132A1 (de) 1977-10-27 1977-10-27 Stabilisator fuer polysaccharid

Publications (2)

Publication Number Publication Date
SE7811083L SE7811083L (sv) 1979-04-28
SE447700B true SE447700B (sv) 1986-12-08

Family

ID=6022367

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7811083A SE447700B (sv) 1977-10-27 1978-10-25 Stabilisering av meningokockpolysackarid, vaccin innehallande polysackariden och stabilisator(er) samt anvendningen av sackaros, raffinos eller glutaminat och eventuellt laktos som stabilisator

Country Status (11)

Country Link
US (1) US4206200A (ja)
JP (1) JPS5470422A (ja)
BE (1) BE871612A (ja)
CA (1) CA1113861A (ja)
DE (1) DE2748132A1 (ja)
DK (1) DK158006C (ja)
ES (1) ES474412A1 (ja)
FI (1) FI61807B (ja)
FR (1) FR2406999A1 (ja)
GB (1) GB2009198B (ja)
SE (1) SE447700B (ja)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4451446A (en) * 1982-03-04 1984-05-29 Smithkline-Rit Process for the preparation of polysaccharide-protein complexes from bacterial capsules, obtained products and immunogenic compositions containing them
GB2187191B (en) * 1984-01-30 1989-11-01 Quadrant Bioresources Ltd Protection of proteins and the like
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
DE229810T1 (de) * 1985-07-09 1987-11-05 Quadrant Bioresources Ltd., Soulbury, Leighton Buzzard, Bedfordshire Beschuetzung von proteinen und aehnlichem.
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4678812A (en) * 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US5102788A (en) * 1988-11-21 1992-04-07 Hygeia Sciences, Inc. Immunoassay including lyophilized reactant mixture
JPH03208485A (ja) * 1990-01-11 1991-09-11 Matsushita Electric Ind Co Ltd 文字放送受信装置
US5200399A (en) * 1990-09-14 1993-04-06 Boyce Thompson Institute For Plant Research, Inc. Method of protecting biological materials from destructive reactions in the dry state
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
PL179443B1 (pl) * 1994-03-07 2000-09-29 Inhale Therapeutic Syst Kompozycja insuliny, sposób wytwarzania kompozycji insuliny i sposób wytwarzania dawki insuliny w postaci aerozolu PL PL PL PL
WO1995033488A1 (en) 1994-06-02 1995-12-14 Quadrant Holdings Cambridge Limited Method of preventing aggregation of various substances upon rehydration or thawing and compositions obtained thereby
GB9508691D0 (en) 1995-04-28 1995-06-14 Pafra Ltd Stable compositions
US5876992A (en) 1996-07-03 1999-03-02 Molecular Biology Resources, Inc. Method and formulation for stabilization of enzymes
US6306404B1 (en) 1998-07-14 2001-10-23 American Cyanamid Company Adjuvant and vaccine compositions containing monophosphoryl lipid A
FR2791895B1 (fr) * 1999-03-23 2001-06-15 Pasteur Merieux Serums Vacc Utilisation de trehalose pour stabiliser un vaccin liquide
US6635261B2 (en) 1999-07-13 2003-10-21 Wyeth Holdings Corporation Adjuvant and vaccine compositions containing monophosphoryl lipid A
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
WO2003035673A1 (en) 2001-10-22 2003-05-01 Dompe S.P.A. Supercritical fluids processing: preparation of protein microparticles and their stabilisation
EP1777236B8 (en) * 2002-03-26 2017-02-22 GlaxoSmithKline Biologicals SA Modified saccharides having improved stability in water for use as a medicament
US20030124139A1 (en) * 2002-11-20 2003-07-03 Irina Esikova Compositions and methods for stabilizing biological molecules upon lyophilization
KR101354093B1 (ko) 2005-03-14 2014-01-24 와이어쓰 엘엘씨 티게사이클린 조성물 및 이의 제조방법
KR20130122810A (ko) * 2005-06-27 2013-11-08 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신 제조 방법
GB0612854D0 (en) * 2006-06-28 2006-08-09 Novartis Ag Saccharide analysis
JP5721704B2 (ja) 2009-06-12 2015-05-20 マイクロニクス, インコーポレイテッド マイクロ流体デバイス内のtaqポリメラーゼを乾燥保存するための再水和可能なマトリックス
CN102803507B (zh) 2009-06-12 2016-05-25 精密公司 用于微流体装置中在板反应剂的脱水储存的组合物及方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2908614A (en) * 1954-08-10 1959-10-13 Glaxo Lab Ltd Use of dextran in freeze-drying process
US3135663A (en) * 1960-06-28 1964-06-02 Glaxo Group Ltd Vaccines
GB995362A (en) * 1962-05-11 1965-06-16 Smith Kline French Lab Improvements in or relating to freeze-drying biological material
DE1183629B (de) * 1962-12-21 1964-12-17 Behringwerke Ag Verfahren zur Stabilisierung biologisch aktiven Materials
US3567585A (en) * 1963-07-12 1971-03-02 Ciba Geigy Corp Process for obtaining bcg-cultures
DE1617350C3 (de) * 1967-06-22 1979-09-06 Behringwerke Ag, 3550 Marburg Verfahren zur Inaktivierung von biologischem Material
US3532790A (en) * 1968-02-23 1970-10-06 Canadian Patents Dev Somatic antigen vaccines from lysed inactivated bacteria and process for producing them
FR7461M (ja) * 1968-06-19 1970-01-05
GB1218277A (en) * 1968-08-20 1971-01-06 Miles Lab Dry water-dispersible aluminium hydroxide gels
US3577527A (en) * 1969-01-27 1971-05-04 Us Navy Neisseria meningitidis antigen
US3599150A (en) * 1969-08-01 1971-08-10 Miles Lab Stabilized aluminum hydroxide suspensions
US3636192A (en) * 1970-01-13 1972-01-18 Us Army Meningococcal polysaccharide vaccines
US3859434A (en) * 1973-01-08 1975-01-07 Canadian Patents Dev Meningococcal antigens

Also Published As

Publication number Publication date
GB2009198B (en) 1982-10-27
BE871612A (fr) 1979-04-27
FR2406999B1 (ja) 1982-11-12
DE2748132C2 (ja) 1989-04-06
SE7811083L (sv) 1979-04-28
DK158006C (da) 1990-08-06
JPS5470422A (en) 1979-06-06
GB2009198A (en) 1979-06-13
DK158006B (da) 1990-03-12
DE2748132A1 (de) 1979-05-03
JPS6310686B2 (ja) 1988-03-08
CA1113861A (en) 1981-12-08
DK477278A (da) 1979-04-28
FI783250A (fi) 1979-04-28
FR2406999A1 (fr) 1979-05-25
ES474412A1 (es) 1979-04-16
US4206200A (en) 1980-06-03
FI61807B (fi) 1982-06-30

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