FI61807B - Foerfarande foer stabilisering av meningokockpolysackarid - Google Patents

Foerfarande foer stabilisering av meningokockpolysackarid Download PDF

Info

Publication number
FI61807B
FI61807B FI783250A FI783250A FI61807B FI 61807 B FI61807 B FI 61807B FI 783250 A FI783250 A FI 783250A FI 783250 A FI783250 A FI 783250A FI 61807 B FI61807 B FI 61807B
Authority
FI
Finland
Prior art keywords
meningococcal
polysaccharide
meningokockpolysackarid
lactose
foerfarande foer
Prior art date
Application number
FI783250A
Other languages
English (en)
Finnish (fi)
Other versions
FI783250A (fi
Inventor
Gerhard Guthoehrlein
Torsten Bertil Helting
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of FI783250A publication Critical patent/FI783250A/fi
Application granted granted Critical
Publication of FI61807B publication Critical patent/FI61807B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
FI783250A 1977-10-27 1978-10-25 Foerfarande foer stabilisering av meningokockpolysackarid FI61807B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2748132 1977-10-27
DE19772748132 DE2748132A1 (de) 1977-10-27 1977-10-27 Stabilisator fuer polysaccharid

Publications (2)

Publication Number Publication Date
FI783250A FI783250A (fi) 1979-04-28
FI61807B true FI61807B (fi) 1982-06-30

Family

ID=6022367

Family Applications (1)

Application Number Title Priority Date Filing Date
FI783250A FI61807B (fi) 1977-10-27 1978-10-25 Foerfarande foer stabilisering av meningokockpolysackarid

Country Status (11)

Country Link
US (1) US4206200A (ja)
JP (1) JPS5470422A (ja)
BE (1) BE871612A (ja)
CA (1) CA1113861A (ja)
DE (1) DE2748132A1 (ja)
DK (1) DK158006C (ja)
ES (1) ES474412A1 (ja)
FI (1) FI61807B (ja)
FR (1) FR2406999A1 (ja)
GB (1) GB2009198B (ja)
SE (1) SE447700B (ja)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4451446A (en) * 1982-03-04 1984-05-29 Smithkline-Rit Process for the preparation of polysaccharide-protein complexes from bacterial capsules, obtained products and immunogenic compositions containing them
GB2187191B (en) * 1984-01-30 1989-11-01 Quadrant Bioresources Ltd Protection of proteins and the like
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
US4891319A (en) * 1985-07-09 1990-01-02 Quadrant Bioresources Limited Protection of proteins and the like
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
US4678812A (en) * 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US5102788A (en) * 1988-11-21 1992-04-07 Hygeia Sciences, Inc. Immunoassay including lyophilized reactant mixture
JPH03208485A (ja) * 1990-01-11 1991-09-11 Matsushita Electric Ind Co Ltd 文字放送受信装置
US5200399A (en) * 1990-09-14 1993-04-06 Boyce Thompson Institute For Plant Research, Inc. Method of protecting biological materials from destructive reactions in the dry state
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
KR100419037B1 (ko) * 1994-03-07 2004-06-12 넥타르 테라퓨틱스 폐를통한인슐린의전달방법및그조성물
CN1188171C (zh) 1994-06-02 2005-02-09 廓德伦特控股剑桥有限公司 防止各种特质在再水化或熔化时聚集的方法以及由此获得的组合物
GB9508691D0 (en) 1995-04-28 1995-06-14 Pafra Ltd Stable compositions
US5876992A (en) * 1996-07-03 1999-03-02 Molecular Biology Resources, Inc. Method and formulation for stabilization of enzymes
US6306404B1 (en) 1998-07-14 2001-10-23 American Cyanamid Company Adjuvant and vaccine compositions containing monophosphoryl lipid A
FR2791895B1 (fr) * 1999-03-23 2001-06-15 Pasteur Merieux Serums Vacc Utilisation de trehalose pour stabiliser un vaccin liquide
US6635261B2 (en) 1999-07-13 2003-10-21 Wyeth Holdings Corporation Adjuvant and vaccine compositions containing monophosphoryl lipid A
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
RU2309160C2 (ru) 2001-10-22 2007-10-27 Домпе фа. р. ма с.п.а. Способ получения микрочастиц белка или полипептида и продукт
PT1490409E (pt) * 2002-03-26 2009-04-03 Novartis Vaccines & Diagnostic Sacáridos modificados possuindo uma estabilidade melhorada em água
US20030124139A1 (en) * 2002-11-20 2003-07-03 Irina Esikova Compositions and methods for stabilizing biological molecules upon lyophilization
PL1858488T5 (pl) 2005-03-14 2024-01-03 Wyeth Llc Kompozycje tygecykliny i sposoby wytwarzania
PT2351578T (pt) * 2005-06-27 2017-04-07 Glaxosmithkline Biologicals Sa Processo para o fabrico de vacinas
GB0612854D0 (en) * 2006-06-28 2006-08-09 Novartis Ag Saccharide analysis
WO2010144682A1 (en) 2009-06-12 2010-12-16 Micronics, Inc. Rehydratable matrices for dry storage of taq polymerase in a microfluidic device
JP5953229B2 (ja) 2009-06-12 2016-07-20 マイクロニクス， インコーポレイテッド マイクロ流体デバイス内でオンボード試薬を脱水保存する組成物および方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2908614A (en) * 1954-08-10 1959-10-13 Glaxo Lab Ltd Use of dextran in freeze-drying process
US3135663A (en) * 1960-06-28 1964-06-02 Glaxo Group Ltd Vaccines
GB995362A (en) * 1962-05-11 1965-06-16 Smith Kline French Lab Improvements in or relating to freeze-drying biological material
DE1183629B (de) * 1962-12-21 1964-12-17 Behringwerke Ag Verfahren zur Stabilisierung biologisch aktiven Materials
US3567585A (en) * 1963-07-12 1971-03-02 Ciba Geigy Corp Process for obtaining bcg-cultures
DE1617350C3 (de) * 1967-06-22 1979-09-06 Behringwerke Ag, 3550 Marburg Verfahren zur Inaktivierung von biologischem Material
US3532790A (en) * 1968-02-23 1970-10-06 Canadian Patents Dev Somatic antigen vaccines from lysed inactivated bacteria and process for producing them
FR7461M (ja) * 1968-06-19 1970-01-05
GB1218277A (en) * 1968-08-20 1971-01-06 Miles Lab Dry water-dispersible aluminium hydroxide gels
US3577527A (en) * 1969-01-27 1971-05-04 Us Navy Neisseria meningitidis antigen
US3599150A (en) * 1969-08-01 1971-08-10 Miles Lab Stabilized aluminum hydroxide suspensions
US3636192A (en) * 1970-01-13 1972-01-18 Us Army Meningococcal polysaccharide vaccines
US3859434A (en) * 1973-01-08 1975-01-07 Canadian Patents Dev Meningococcal antigens

Also Published As

Publication number Publication date
DK158006B (da) 1990-03-12
US4206200A (en) 1980-06-03
JPS6310686B2 (ja) 1988-03-08
DK158006C (da) 1990-08-06
DK477278A (da) 1979-04-28
BE871612A (fr) 1979-04-27
DE2748132A1 (de) 1979-05-03
ES474412A1 (es) 1979-04-16
GB2009198B (en) 1982-10-27
JPS5470422A (en) 1979-06-06
CA1113861A (en) 1981-12-08
DE2748132C2 (ja) 1989-04-06
SE447700B (sv) 1986-12-08
FR2406999B1 (ja) 1982-11-12
FI783250A (fi) 1979-04-28
GB2009198A (en) 1979-06-13
FR2406999A1 (fr) 1979-05-25
SE7811083L (sv) 1979-04-28

Similar Documents

Publication Publication Date Title
FI61807B (fi) Foerfarande foer stabilisering av meningokockpolysackarid
FI79024C (fi) Foerfarande foer framstaellning av haemophilus influenzae b-polysackaridexotoxoidkonjugatvaccin.
EP0130619B1 (en) Hepatitis b vaccine and method for its preparation
KR930010623B1 (ko) 백금계 항암화합물의 안정한 동결건조물의 제조방법
US4460575A (en) Vaccinal complex containing a specific antigen and vaccine containing it
de Belder Dextran
DE69620271T2 (de) Polyribosylribitol-phosphat enthaltende Haemophilus-influenzae-Typ-b-Impfstoffzubereitung und Verfahren zur deren Herstellung
JPH11503719A (ja) 乾燥組成物
KR20090007588A (ko) 니코틴-담체 백신 제제
US20070031447A1 (en) Method of isolating biologically active fraction containing clinically acceptable native S-lipopolysaccharides obtained from bacteria producing endotoxic lipopolysaccharides
US5424287A (en) Extract of bacterial macromolecules, a process for its preparation and a pharmaceutical composition containing the same
US4134214A (en) Freeze-drying process for the preparation of meningococcus vaccine without degradation of potency
JPH0236236B2 (ja)
DD299213A7 (de) Verfahren zur stabilisierung eines lebendvirusimpfstoffes gegen temperatureinwirkung
JPH07157431A (ja) 安定なプロスタグランジンｅ製剤
EP0702960A1 (en) Liquid globulin composition for intravenous injection, process for producing the same, and method of inhibiting globulin dimer increase in said composition
IL30448A (en) Protein metal chelate composition stabilized with saccharide,and preparation thereof
DE3601922A1 (de) Stabilisiertes virus-antigen, verfahren zu seiner herstellung und seine verwendung
US4954522A (en) Lyophilized preparation of platinum compound
JPH08509374A (ja) 生存可能な細菌
JPS5959625A (ja) ガン壊死因子を安定化する方法
EP0036514B1 (de) Verwendung eines aus Blutserum gewonnenen Wirkstoffes zur Stabilisierung von Prostaglandinen
EP0230556B1 (en) Fraction obtained from listeria monocytogenes having therapeutical activity, process for its preparation and pharmaceutical compositions containing it
JPS624369B2 (ja)
CN117018177A (zh) 冻干用狂犬病疫苗组合物及其制备方法和应用

Legal Events

Date Code Title Description
FC Application refused

Owner name: BEHRINGWERKE AKTIENGESELLSCHAFT