SE447254B - Nya derivat av trimetoxi-3,4,5-cinnamoyl-piperazin och deras salter, deras framstellningssett samt lekemedel - Google Patents

Nya derivat av trimetoxi-3,4,5-cinnamoyl-piperazin och deras salter, deras framstellningssett samt lekemedel

Info

Publication number
SE447254B
SE447254B SE8100291A SE8100291A SE447254B SE 447254 B SE447254 B SE 447254B SE 8100291 A SE8100291 A SE 8100291A SE 8100291 A SE8100291 A SE 8100291A SE 447254 B SE447254 B SE 447254B
Authority
SE
Sweden
Prior art keywords
formula
compounds
compound
radical
group
Prior art date
Application number
SE8100291A
Other languages
English (en)
Swedish (sv)
Inventor
J-F Ancher
A Lacour
G Moinet
J Tisne-Versailles
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8001242A external-priority patent/FR2474031A1/fr
Priority claimed from FR8100178A external-priority patent/FR2497512A2/fr
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of SE447254B publication Critical patent/SE447254B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8100291A 1980-01-21 1981-01-20 Nya derivat av trimetoxi-3,4,5-cinnamoyl-piperazin och deras salter, deras framstellningssett samt lekemedel SE447254B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8001242A FR2474031A1 (fr) 1980-01-21 1980-01-21 Nouveaux derives de la trimethoxy-3,4,5 cinnamoyle piperazine, leurs sels, leur procede de preparation et leur application en therapeutique
FR8100178A FR2497512A2 (fr) 1981-01-07 1981-01-07 Nouveaux derives de la trimethoxy-3,4,5 cinnamoyl piperazine, leurs sels, leur procede de preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
SE447254B true SE447254B (sv) 1986-11-03

Family

ID=26221561

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8100291D SE8100291L (sv) 1980-01-21 1981-01-20 Nya derivat av trimetoxi-3,4,5 cinnamoyl piperazin, deras salter, deras framstellningssett och deras terapeutiska anvendning
SE8100291A SE447254B (sv) 1980-01-21 1981-01-20 Nya derivat av trimetoxi-3,4,5-cinnamoyl-piperazin och deras salter, deras framstellningssett samt lekemedel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE8100291D SE8100291L (sv) 1980-01-21 1981-01-20 Nya derivat av trimetoxi-3,4,5 cinnamoyl piperazin, deras salter, deras framstellningssett och deras terapeutiska anvendning

Country Status (12)

Country Link
US (1) US4368199A (ru)
AU (1) AU541527B2 (ru)
CA (1) CA1151649A (ru)
CH (1) CH647516A5 (ru)
DE (1) DE3101798A1 (ru)
ES (1) ES8204732A1 (ru)
GB (1) GB2067562B (ru)
GR (1) GR71991B (ru)
IT (1) IT1135111B (ru)
LU (1) LU83070A1 (ru)
NL (1) NL8100291A (ru)
SE (2) SE8100291L (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5888370A (ja) * 1981-11-19 1983-05-26 Hokuriku Seiyaku Co Ltd 1−(3,4,5−トリメトキシシンナモイル)−4−アミノカルボニルエチル置換ピペラジン及びホモピペラジン誘導体、及びその製造方法
US4499100A (en) * 1983-05-18 1985-02-12 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade
US4558129A (en) * 1983-05-18 1985-12-10 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
IT1207990B (it) * 1983-11-15 1989-06-01 Euroresearch Srl Attivita' analgesica, processo per derivati metil-piperazinici edla loro preparazione e composizioni terapeutiche che li contengono.
US5179095A (en) * 1986-02-26 1993-01-12 Eisai Co., Ltd. Piperidine derivative and pharmaceutical composition containing the same
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
US5026707A (en) * 1988-05-23 1991-06-25 Eli Lilly And Company Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
CA1335591C (en) * 1988-05-23 1995-05-16 James Arthur Nixon Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
US5177089A (en) * 1988-06-01 1993-01-05 Eisai Co., Ltd. Butenoic or propenoic acid derivative
FI892362A (fi) * 1988-06-01 1989-12-02 Eisai Co Ltd Buten- eller propensyraderivat.
SE0400440D0 (sv) * 2004-02-25 2004-02-25 Active Biotech Ab Novel Cinnamic Amides
CN101979386A (zh) * 2009-12-17 2011-02-23 海南康虹医药科技开发有限公司 制备桂哌齐特游离碱的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT200149B (de) 1956-04-20 1958-10-25 Lab Pharmaceutica Dr C Janssen Verfahren zur Herstellung von neuen Piperazinderivaten
GB1168108A (en) * 1967-09-29 1969-10-22 Delalande Sa Amide Derivatives of 1-Piperazine Acetic Acid and Process for their Preparation
GB1218591A (en) * 1968-04-03 1971-01-06 Delalande Sa Derivatives of n-(3,4,5-trimethoxy cennamoyl) piperazine and their process of preparation
US3753984A (en) * 1971-05-26 1973-08-21 Delalande Sa Amides derived from the esters of 1-piperazine propionic acid, their method of preparation and their application to therapeutics
CH583713A5 (ru) * 1973-06-29 1977-01-14 Cermol Sa
FR2278340A1 (fr) * 1974-07-17 1976-02-13 Delalande Sa Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique
GB1473262A (en) * 1974-11-20 1977-05-11 Delalande Sa Derivatives of n-3,4,5-trimethoxy cinnamoyl-piperazine their process of preparation and their therapeutic application
FR2387971A1 (fr) * 1977-04-19 1978-11-17 Delalande Sa Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
ES499299A0 (es) 1982-06-01
IT1135111B (it) 1986-08-20
US4368199A (en) 1983-01-11
CA1151649A (en) 1983-08-09
LU83070A1 (fr) 1982-09-10
NL8100291A (nl) 1981-08-17
AU541527B2 (en) 1985-01-10
AU6634881A (en) 1981-07-30
GR71991B (ru) 1983-08-26
ES8204732A1 (es) 1982-08-01
IT8119242A0 (it) 1981-01-21
DE3101798C2 (ru) 1990-10-04
GB2067562A (en) 1981-07-30
SE8100291L (sv) 1981-07-22
DE3101798A1 (de) 1982-02-18
CH647516A5 (fr) 1985-01-31
GB2067562B (en) 1983-06-22

Similar Documents

Publication Publication Date Title
SE447254B (sv) Nya derivat av trimetoxi-3,4,5-cinnamoyl-piperazin och deras salter, deras framstellningssett samt lekemedel
US3631055A (en) Thiazolyl and pyridyl aminoalcohols
US3775422A (en) Unsymmetrical 1,4-dihydro-4-aryl-nicotinate esters
US3474101A (en) Thebaine and oripavine derivatives
SE460788B (sv) Piperazinderivat, foerfarande foer framstaellning av dessa och farmaceutisk komposition med stimulerande, skyddande och/eller korrigerande verkan paa hjaernfunktionerna
GB1585978A (en) Dihydropyridine compounds their production and their medicinal use
US3862161A (en) 4-pyridyl substituted 1,4-dihydropyridines
US5144037A (en) 1,5-dideoxy-1,5-imino-d-glucitol derivatives
Uyeo et al. Lycoris Alkaloids. XXIV.: Isolation and Characterization of Lycoremine.
CH631448A5 (de) Verfahren zur herstellung neuer piperazinderivate.
CA2080536A1 (en) Nicotinic activity of a series of arecolones and isoarecolones
US3330831A (en) Aminoalkoxy-diphenyl amines, ethers and thioethers
US3943140A (en) 2,3,5,6-Tetracarboxy-1,4-dihydropyridine derivatives
US2830008A (en) Amines
EP0657455A1 (en) Epi-epibatidine derivatives, a process and intermediates for preparing them and epi-epibatidine and medicaments containing the epi-epibatidine derivatives and/or epi-epibatidine and the use of them
TW200300346A (en) Aryl fused azapolycyclic compounds
EP0002066B1 (en) 2-adamantyl hydrazines and pharmaceutical compositions containing them
JPS6055505B2 (ja) 新規オキシムエ−テル化合物及びその製造方法
US2977359A (en) Amides and hydrazones of podophyllic acid and picropodophyllic acid
WO1982002045A1 (en) Pyridine derivatives
US3184452A (en) New aminoalkoxy compounds and process for theik manufacture
FR2518089A1 (fr) Ethers d'oximes de pyridyl-1 pentanone-3, leur procede de preparation et leur utilisation comme medicament
US3405139A (en) Phenyl-cyclohexylalkylamine compounds
US3971796A (en) 1,4-Dihydropyridine esters
CS249503B2 (en) Method of new 1-(3-/3,4,5-trimethoxyphenoxy/-2-hydroxypropyl-4-aryl-piperazine derivatives production

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8100291-7

Effective date: 19940810